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$178 Cheap Flights from Rochester (ROC) to St. Louis (STL)

View $178 flight on Fri, Oct 30, 2026Opens in a new window

Popular airlines from Greater Rochester Intl. Airport (ROC) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Rochester to St. Louis (ROC-STL)

Prices were available within the past 7 days and start at $178 for one-way flights and $340 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Thu, Nov 12 - Tue, Nov 17
ROC
Rochester
STL
St. Louis
$340 Roundtrip, found 4 days ago
$340
Roundtrip
found 4 days ago
Select United flight, departing Thu, Nov 12 from Rochester to St. Louis, returning Tue, Nov 17, priced at $340 found 4 days ago
United
Thu, Oct 1 - Mon, Oct 5
ROC
Rochester
STL
St. Louis
$344 Roundtrip, found 4 days ago
$344
Roundtrip
found 4 days ago
Select United flight, departing Thu, Oct 1 from Rochester to St. Louis, returning Mon, Oct 5, priced at $344 found 4 days ago
American Airlines
Thu, Oct 1 - Mon, Oct 5
ROC
Rochester
STL
St. Louis
$351 Roundtrip, found 4 days ago
$351
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Oct 1 from Rochester to St. Louis, returning Mon, Oct 5, priced at $351 found 4 days ago
United
Mon, Nov 23 - Fri, Nov 27
ROC
Rochester
STL
St. Louis
$362 Roundtrip, found 4 days ago
$362
Roundtrip
found 4 days ago
Select United flight, departing Mon, Nov 23 from Rochester to St. Louis, returning Fri, Nov 27, priced at $362 found 4 days ago
American Airlines
Thu, Oct 1 - Mon, Oct 5
ROC
Rochester
STL
St. Louis
$369 Roundtrip, found 4 days ago
$369
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Oct 1 from Rochester to St. Louis, returning Mon, Oct 5, priced at $369 found 4 days ago
Southwest Airlines
Wed, Nov 4 - Fri, Nov 6
ROC
Rochester
STL
St. Louis
$381 Roundtrip, found 1 day ago
$381
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, Nov 4 from Rochester to St. Louis, returning Fri, Nov 6, priced at $381 found 1 day ago
United
Sat, Nov 7 - Sun, Nov 8
ROC
Rochester
STL
St. Louis
$384 Roundtrip, found 1 day ago
$384
Roundtrip
found 1 day ago
Select United flight, departing Sat, Nov 7 from Rochester to St. Louis, returning Sun, Nov 8, priced at $384 found 1 day ago
United
Thu, Nov 5 - Mon, Nov 9
ROC
Rochester
STL
St. Louis
$386 Roundtrip, found 2 hours ago
$386
Roundtrip
found 2 hours ago
Select United flight, departing Thu, Nov 5 from Rochester to St. Louis, returning Mon, Nov 9, priced at $386 found 2 hours ago
Southwest Airlines
Tue, Oct 6 - Wed, Oct 7
ROC
Rochester
STL
St. Louis
$391 Roundtrip, found 2 hours ago
$391
Roundtrip
found 2 hours ago
Select Southwest Airlines flight, departing Tue, Oct 6 from Rochester to St. Louis, returning Wed, Oct 7, priced at $391 found 2 hours ago
Delta
Thu, Nov 5 - Mon, Nov 9
ROC
Rochester
STL
St. Louis
$394 Roundtrip, found 2 hours ago
$394
Roundtrip
found 2 hours ago
Select Delta flight, departing Thu, Nov 5 from Rochester to St. Louis, returning Mon, Nov 9, priced at $394 found 2 hours ago

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $477
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $477

What you need to know for your flight from Greater Rochester Intl. to Lambert-St. Louis Intl.

Rochester (ROC) to St. Louis (STL) at a glance

Travel from Rochester (ROC) to St. Louis (STL) with a choice of airlines on this domestic short-haul route. Whether you prefer full-service or budget-friendly carriers, you can easily compare options to find the itinerary that aligns with your budget, schedule, and travel plans while discovering the iconic sights and neighborhoods of St. Louis. Get ready to explore key details for flights from Greater Rochester International Airport (ROC) to Lambert-St. Louis International Airport (STL).

  • Fastest flight duration: around 3h 30m in-flight, plus roughly 1h 15m layover with one stop
  • Route distance: roughly 700 miles (1,130 km)
  • Flights per week: around 10 departures on average
  • Typical fares (one-way): economy tickets often range from $120–$370, depending on seasonality and how far ahead you book

Flights from Greater Rochester International Airport (ROC) to Lambert-St. Louis International Airport (STL)

Recent traveler bookings reveal the top airlines favored for flights from Rochester to St. Louis, primarily for their one-stop service. Common layover points include Detroit Metropolitan Wayne County Airport (DTW) with an approximately 1-hour layover, O'Hare International Airport (ORD) at about 1 hour and 30 minutes, and Ronald Reagan Washington National Airport (DCA), also around 1 hour and 30 minutes. This variety allows you to mix and match options based on price, overall travel duration, and cabin class to create the ideal itinerary.

  • American Airlines: This full-service airline provides one-stop flights, with one-way ticket prices generally between $125 and $380. It facilitates about 40% of departures along this route, featuring an in-flight duration of 3 hours and 30 minutes and a total travel time of around 5 hours, including layover.
  • Delta: Another full-service option, Delta offers one-stop journeys with one-way fares usually ranging from $145 to $385. They account for approximately 37% of the departures on this route, with in-flight times of 3 hours and 30 minutes and a total estimated travel time of 5 hours, factoring in layovers.
  • United: This full-service airline features one-stop services with one-way fares typically priced between $120 and $375. United represents about 12% of departures on this route, boasting an in-flight duration of 3 hours and 30 minutes, with a total journey time nearing 5 hours, including any layover.
  • Southwest Airlines: As a low-cost carrier, Southwest offers one-stop service with one-way fares usually between $120 and $370. It also accounts for around 12% of the departures on this route, providing an in-flight time of 3 hours and 30 minutes along with a total travel duration of approximately 5 hours, including layover.

Travelers flying from Rochester to St. Louis can enhance their journey by upgrading to Delta's first class or premium economy service on this route for a more comfortable experience.

Best time to fly from Rochester (ROC) to St. Louis (STL)

The most popular months for travelers flying from Rochester to St. Louis are February, April, and October, when peak temperatures in St. Louis reach up to 58.6°F in October. If you prefer quieter travel, consider September, the least busy time to visit with temperatures around 70.9°F and typically the lowest average one-way fare (around $198). Flight availability peaks in November and December, with approximately 12 flights per week, making it easier to find convenient departure times. January has the fewest flights, with approximately 8 flights per week.

  • Cheapest time to fly: September usually offers good deals with average one-way fare around $198, roughly 14% cheaper than the yearly average.
  • More budget-friendly months to fly: October, May, and March typically offer average one-way fares roughly ranging from $205 to $216.
  • Most flight options: November and December have the highest number of flights from Rochester to St. Louis, with approximately 12 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January31.6°F (-0.2°C)Average8$283
February34.9°F (1.6°C)Slightly High9$238
March46.4°F (8.0°C)Slightly Low9$216
April56.1°F (13.4°C)Slightly High9$239
May66.6°F (19.2°C)Slightly Low11$210
June76.1°F (24.5°C)Average11$225
July78.6°F (25.9°C)Average9$246
August77.0°F (25.0°C)Average11$253
September70.9°F (21.6°C)Slightly Low9$198
October58.6°F (14.8°C)Slightly High11$205
November46.2°F (7.9°C)Average12$228
December37.8°F (3.2°C)Average12$225

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative route from Rochester (ROC) to St. Louis (STL)

  • Buffalo to St. Louis (BUF-STL): Located approximately 56 miles from Greater Rochester International Airport (ROC), Buffalo Niagara International Airport (BUF) serves as a convenient departure point. One-way economy fares for this journey generally fall between $110 and $390, influenced by the season and how far in advance you book. Travelers can choose from both non-stop and one-stop flights, with common layover spots being O'Hare International Airport (ORD) and Detroit Metropolitan Wayne County Airport (DTW). Major airlines operating on this route include American Airlines and Delta, with options for business and first-class service available as well.

How to find the best prices for flights from Rochester (ROC) to St. Louis (STL)

Getting some of the best deals on flights from Rochester to St. Louis is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking 2-8 weeks in advance, which aligns with when most travelers make their reservations. Evening departures from 6 PM to 12 AM often offer lower prices, while morning flights from 5 AM to 12 PM are the most popular. Additionally, flying on Tuesday typically yields cheaper fares, although Wednesday is the most favored travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Lambert-St. Louis International Airport from Greater Rochester International Airport

St. Louis welcomes travelers from Rochester with a range of transport options based on price, convenience, and proximity. Here's how to reach St. Louis efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in St. Louis, with private rides that can be arranged in advance.
  • Car rental: Renting a car from Lambert-St. Louis International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Lambert-St. Louis International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Lambert-St. Louis International Airport, Lambert Main Terminal Station, a metro station, is located about 0.1 miles away on foot, providing easy access to public transport for travelers.

Frequently asked questions

How much does a flight from Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) cost?
You can find cheap one-way flights from $178 and cheap return flights from $340 Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) with Expedia. One-way flights usually range from $163 to $715, and return flights typically cost between $364 and $973. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
September is the cheapest month to fly from Rochester (ROC) to St. Louis (STL), with average round-trip fares around $326. This price is about 21% lower than the average throughout the year, as September typically sees a decrease in travel after the summer peak. Other cheap months to fly from Rochester to St. Louis include May and June.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Enter ROC to STL and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Southwest Airlines is one of the cheapest airlines offering connecting flights from Rochester (ROC) to St. Louis (STL), with round-trip tickets starting from around $206 with a layover in Baltimore Washington Intl. Thurgood Marshall (BWI). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
To find a cheap flight from Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The best times to fly from Rochester to St. Louis are September and May. You can expect to pay around $326 for a return flight during these months. September is ideal for pleasant weather, while May offers a great spring experience.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The earliest flight from Greater Rochester International Airport (ROC) to Lambert-St. Louis International Airport (STL) typically departs at around 5:00 AM, operated by American Airlines. This seasonal service is available in December, making it a good option for holiday travel. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The most popular departure times for flights from Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) are in the early morning, from 6am to 9am. About 32% of passengers prefer this time window. Many major carriers, including Delta, United and American Airlines, offer flights during this window. This timing works well because it allows you to start your day early and arrive in St. Louis with plenty of time to explore.
How long does it take to fly from Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
A flight from ROC to STL with a layover takes around 5 hours 20 minutes, with the route covering approximately 728 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
First class is available on flights from ROC to STL. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight with Expedia?
It's easy to earn miles on a Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for St. Louis from Greater Rochester Intl. (ROC)?
From Greater Rochester Intl. (ROC), you can fly into Lambert-St. Louis Intl. (STL) to reach St. Louis. Some flights may connect through major hubs like Baltimore Washington Intl. Thurgood Marshall (BWI), Washington Dulles Intl. (IAD), Midway Intl. (MDW) before reaching St. Louis. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) at the last minute?
Typically, booking a last minute flight from Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight and hotel package?
Securing a Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) St Louis Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
If you booked your Rochester, NY (ROC-Greater Rochester Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Greater Rochester Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$339
Distance
727 mi

Book with confidence

Rochester to St. Louis Flights

The cheapest times to fly from Rochester to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Rochester to St. Louis are during the month of November. You can find some of the cheapest flights from Rochester to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Rochester to St. Louis

Sunday is one of the best days to book for cheap flights from Rochester to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Rochester to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Rochester to St. Louis in 2026. You can also book with separate airlines for your outbound and return journeys, from $178 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Rochester to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Rochester to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Rochester to St. Louis Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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