A large bridge spanning a body of water with a city skyline in the background.

$191 Cheap Flights from Fort Myers (RSW) to San Diego (SAN)

View $191 flight on Wed, Oct 7, 2026Opens in a new window

Popular airlines from Southwest Florida Intl. Airport (RSW) to San Diego Intl. Airport (SAN)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 30% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Fort Myers to San Diego (RSW-SAN)

Prices were available within the past 7 days and start at $191 for one-way flights and $374 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Bargain Flight
Sat, Jan 9 - Wed, Jan 20
RSW
Fort Myers
SAN
San Diego
$374 Roundtrip, found 2 days ago
$374
Roundtrip
found 2 days ago
Select Bargain Flight flight, departing Sat, Jan 9 from Fort Myers to San Diego, returning Wed, Jan 20, priced at $374 found 2 days ago
Southwest Airlines
Tue, Nov 3 - Fri, Nov 6
RSW
Fort Myers
SAN
San Diego
$375 Roundtrip, found 3 days ago
$375
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Tue, Nov 3 from Fort Myers to San Diego, returning Fri, Nov 6, priced at $375 found 3 days ago
American Airlines
Wed, Mar 31 - Sat, Apr 3
RSW
Fort Myers
SAN
San Diego
$376 Roundtrip, found 2 days ago
$376
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Mar 31 from Fort Myers to San Diego, returning Sat, Apr 3, priced at $376 found 2 days ago
American Airlines
Wed, Oct 7 - Tue, Oct 13
RSW
Fort Myers
SAN
San Diego
$381 Roundtrip, just found
$381
Roundtrip
just found
Select American Airlines flight, departing Wed, Oct 7 from Fort Myers to San Diego, returning Tue, Oct 13, priced at $381 just found
JetBlue Airways
Tue, Mar 30 - Tue, Apr 6
RSW
Fort Myers
SAN
San Diego
$386 Roundtrip, found 3 hours ago
$386
Roundtrip
found 3 hours ago
Select JetBlue Airways flight, departing Tue, Mar 30 from Fort Myers to San Diego, returning Tue, Apr 6, priced at $386 found 3 hours ago
Southwest Airlines
Tue, Mar 30 - Tue, Apr 6
RSW
Fort Myers
SAN
San Diego
$386 Roundtrip, found 3 hours ago
$386
Roundtrip
found 3 hours ago
Select Southwest Airlines flight, departing Tue, Mar 30 from Fort Myers to San Diego, returning Tue, Apr 6, priced at $386 found 3 hours ago
Southwest Airlines
Tue, Nov 3 - Fri, Nov 6
RSW
Fort Myers
SAN
San Diego
$389 Roundtrip, found 3 days ago
$389
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Tue, Nov 3 from Fort Myers to San Diego, returning Fri, Nov 6, priced at $389 found 3 days ago
Frontier Airlines
Sat, Nov 21 - Wed, Nov 25
RSW
Fort Myers
SAN
San Diego
$390 Roundtrip, found 21 hours ago
$390
Roundtrip
found 21 hours ago
Select Frontier Airlines flight, departing Sat, Nov 21 from Fort Myers to San Diego, returning Wed, Nov 25, priced at $390 found 21 hours ago
JetBlue Airways
Fri, Jan 8 - Tue, Jan 26
RSW
Fort Myers
SAN
San Diego
$391 Roundtrip, found 5 hours ago
$391
Roundtrip
found 5 hours ago
Select JetBlue Airways flight, departing Fri, Jan 8 from Fort Myers to San Diego, returning Tue, Jan 26, priced at $391 found 5 hours ago
Southwest Airlines
Tue, Feb 2 - Tue, Feb 9
RSW
Fort Myers
SAN
San Diego
$391 Roundtrip, found 1 day ago
$391
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Tue, Feb 2 from Fort Myers to San Diego, returning Tue, Feb 9, priced at $391 found 1 day ago

Alternative airports near San Diego

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to San Diego Intl. SAN. Cheapest and Closest option available. Average driving time to city center is 5 minutes. Flights from $523
SAN
San Diego Intl.
CheapestClosest
Average driving time to city center5 min
Flights from $523

What you need to know for your flight from Southwest Florida Intl. to San Diego Intl.

Fort Myers (RSW) to San Diego (SAN) at a glance

Embark on your journey from Fort Myers (RSW) to San Diego (SAN) with a selection of airlines offering this domestic long-haul route. Whether you prefer full-service carriers or budget options, you can easily compare choices to discover the flight that aligns with your budget, schedule, and travel plans. As you prepare to explore San Diego's renowned attractions and vibrant neighborhoods, gather the essential details for flights departing from Southwest Florida International Airport (RSW) to San Diego International Airport (SAN).

  • Fastest flight duration: around 8 hours non-stop
  • Route distance: roughly 2,200 miles (3,540 km)
  • Flights per week: around 15+ flights with multiple daily departures on average
  • Typical fares (one-way): economy tickets often range from $140–$535, depending on seasonality and how far ahead you book

Flights from Southwest Florida International Airport (RSW) to San Diego International Airport (SAN)

According to recent traveler bookings, the top airlines for flights from Fort Myers to San Diego are popular for both non-stop and one-stop options. Common layover points include Dallas-Fort Worth International Airport (DFW) with a layover of about 1 hour and 15 minutes, Hartsfield-Jackson Atlanta International Airport (ATL) with a roughly 1-hour layover, and George Bush Intercontinental Airport (IAH) also with about a 1 hour and 15 minutes layover. This variety allows you to balance price, total travel time, and cabin class to find the ideal itinerary.

  • American Airlines: This comprehensive carrier provides one-stop options, with one-way fares generally falling between $145 and $695. It represents about 34% of departures on this route, featuring an in-flight duration of 6 hours and 30 minutes, leading to a total travel time of approximately 8 hours, including layovers.
  • United: As a full-service airline, United offers both non-stop and one-stop flights. Their one-way fares typically range from $160 to $665, accounting for around 26% of departures on this route. Expect an in-flight time of 6 hours and 30 minutes, resulting in a total journey time near 8 hours.
  • Delta: Delta is another full-service airline that provides one-stop flights, with one-way prices generally between $140 and $535. They handle approximately 23% of departures on this route, with an in-flight duration of 6 hours and 30 minutes and an overall journey time of about 8 hours, including layovers.
  • Southwest Airlines: This budget-friendly carrier offers one-stop service, with one-way fares usually ranging from $140 to $535. It covers around 11% of departures on this route and features an in-flight time of 6 hours and 30 minutes, leading to a total journey time of roughly 8 hours, including layovers.
  • Frontier Airlines: As a low-cost option, Frontier provides one-stop service with one-way fares typically between $140 and $340. They represent about 2% of departures on this route, with an in-flight time of 6 hours and 30 minutes, resulting in a total travel time of around 8 hours, including layovers.

Travelers flying from Fort Myers to San Diego have the option to upgrade their flight. American Airlines and United both offer first class, while Delta provides choices in both first class and premium economy class for a more comfortable journey.

Best time to fly from Fort Myers (RSW) to San Diego (SAN)

The most popular months for travelers flying from Fort Myers to San Diego are February, March, and April, when peak temperatures in San Diego reach up to 60.6°F in April. If you prefer quieter travel, consider August, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 72.3°F. For better deals, October usually offers the lowest average one-way fare around $243. Flight availability peaks in June, with approximately 18 flights per week, making it easier to find convenient departure times.

  • Cheapest time to fly: October usually offers good deals with average one-way fare around $243, roughly 16% cheaper than the yearly average.
  • Another budget-friendly time to fly: August typically offers an average one-way fare of around $245.
  • Most flight options: June has the highest number of flights from Fort Myers to San Diego, with approximately 18 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January57.4°F (14.1°C)Average14$315
February56.8°F (13.8°C)Moderately High15$268
March58.1°F (14.5°C)Moderately High15$325
April60.6°F (15.9°C)Moderately High16$322
May62.6°F (17.0°C)Average14$293
June66.4°F (19.1°C)Average18$293
July70.5°F (21.4°C)Moderately Low14$307
August72.3°F (22.4°C)Moderately Low14$245
September72.0°F (22.2°C)Moderately Low14$284
October68.2°F (20.1°C)Average16$243
November62.6°F (17.0°C)Average16$312
December57.4°F (14.1°C)Average15$288

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from Fort Myers (RSW) to San Diego (SAN)

  • Fort Myers to San Diego (RSW-MYF): Montgomery Field Airport (MYF) lies approximately 6 miles from San Diego International Airport (SAN).
  • Fort Myers to San Diego (FMY-SAN): Page Field Airport (FMY) is located about 8 miles from Southwest Florida International Airport (RSW).
  • Fort Myers to Carlsbad (RSW-CLD): McClellan-Palomar Airport (CLD) is roughly 28 miles away from San Diego International Airport (SAN).

How to find the best prices for flights from Fort Myers (RSW) to San Diego (SAN)

Getting some of the best deals on flights from Fort Myers to San Diego is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking 2-8 weeks in advance, which aligns with when most travelers make their reservations. Afternoon departures (12pm-6pm) often offer lower prices, while morning flights (5am-12pm) are the most popular. Additionally, flying on Monday typically provides cheaper prices, although Thursday remains the most favored travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find San Diego hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at San Diego International Airport from Southwest Florida International Airport

San Diego welcomes travelers from Fort Myers with a range of transport options based on price, convenience, and proximity. Here's how to reach San Diego efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in San Diego, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from San Diego International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at San Diego International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From San Diego International Airport, Seaport, a seaport, is located about 0.1 miles away on foot, while Middletown Station, a metro station, is approximately 2.3 miles from the airport and typically reached by car. Additionally, B Street Cruise Ship Terminal, a cruise terminal, is situated about 3 miles away by car, providing convenient access to various transportation options.

Frequently asked questions

How much does a flight from Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.) cost?
You can find cheap one-way flights from $191 and cheap return flights from $374 Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.) with Expedia. One-way flights generally range between $174 and $895, and roundtrip flights usually range from $379 to $2426. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.)?
August is the cheapest month to fly from Fort Myers (RSW) to San Diego (SAN), with average return fares around $342. This is about 16% lower than the average price throughout the year, as August often has lower travel demand. Other economical months to fly from Fort Myers to San Diego include February and May.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.)?
Enter RSW to SAN and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.)?
Sun Country Airlines is one of the cheapest airlines offering connecting flights from Fort Myers (RSW) to San Diego (SAN), with return tickets starting from around $501. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.)?
To find a cheap flight from Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.)?
For flights from Fort Myers, FL (RSW) to San Diego, CA (SAN), August and May are the best months to consider. Return flights during these months average around $342, providing a good balance of price and availability. August is particularly appealing due to the warm weather in San Diego, perfect for outdoor activities.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.)?
The earliest flight from Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.) typically departs at around 5:00 AM, operated by WN. This seasonal service is available in March, allowing you to start your day early in sunny San Diego. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.)?
The most popular departure times for flights from Fort Myers, FL (RSW) to San Diego, CA (SAN) are in the early morning, from 6am to 9am. This time window accounts for around 38% of total traffic. Major airlines, including American Airlines, United Airlines, and Southwest Airlines, operate flights during this time, making it a great choice for early travelers.
How long does it take to fly from Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.)?
Flights from RSW to SAN with one stop typically take around 9 hours 30 minutes, covering approximately 2,161 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.)?
First class seats are offered on the RSW to SAN route. First class cabins are available on:

  • American Airlines
  • Delta Air Lines
  • United Airlines

How do I earn miles on a Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.) flight with Expedia?
It's easy to earn miles on a Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for San Diego from Southwest Florida Intl. (RSW)?
From Southwest Florida Intl. (RSW), you can fly into San Diego Intl. (SAN) to reach San Diego. Some flights may connect through major hubs like George Bush Intercontinental (IAH), O'Hare Intl. (ORD), Midway Intl. (MDW) before reaching San Diego. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.) at the last minute?
Typically, booking a last minute flight from Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.) flight and hotel package?
Securing a Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.) San Diego Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.)?
If you booked your Fort Myers, FL (RSW-Southwest Florida Intl.) to San Diego, CA (SAN-San Diego Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Southwest Florida Intl.
Destination airport
San Diego Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Frontier Airlines, JetBlue Airways, Southwest Airlines, Sun Country Airlines, United
Roundtrip price
$374
Distance
2160 mi
Average flight time
11 hours 20 mins

Book with confidence

Fort Myers to San Diego Flights

The cheapest times to fly from Fort Myers to San Diego

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Fort Myers to San Diego are during the month of January. You can find some of the cheapest flights from Fort Myers to San Diego with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Fort Myers to San Diego

Sunday is one of the best days to book for cheap flights from Fort Myers to San Diego: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Fort Myers to San Diego

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Fort Myers to San Diego in 2026. You can also book with separate airlines for your outbound and return journeys, from $191 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Fort Myers to San Diego flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Fort Myers to San Diego airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Fort Myers to San Diego Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

Explore a world of travel with Expedia