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$239 Cheap Flights from Santo Domingo (SDQ) to Buffalo (BUF)

View $239 flight on Thu, Nov 5, 2026Opens in a new window

Popular airlines from Las Americas Intl. Airport (SDQ) to Buffalo Niagara Intl. Airport (BUF)

Cheap Flights from Santo Domingo to Buffalo (SDQ-BUF)

Prices were available within the past 7 days and start at $239 for one-way flights and $379 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Mon, Oct 19 - Wed, Nov 4
SDQ
Santo Domingo
BUF
Buffalo
$379 Roundtrip, found 1 day ago
$379
Roundtrip
found 1 day ago
Select United flight, departing Mon, Oct 19 from Santo Domingo to Buffalo, returning Wed, Nov 4, priced at $379 found 1 day ago
United
Thu, Oct 29 - Thu, Nov 5
SDQ
Santo Domingo
BUF
Buffalo
$385 Roundtrip, found 1 day ago
$385
Roundtrip
found 1 day ago
Select United flight, departing Thu, Oct 29 from Santo Domingo to Buffalo, returning Thu, Nov 5, priced at $385 found 1 day ago
United
Mon, Oct 19 - Wed, Nov 4
SDQ
Santo Domingo
BUF
Buffalo
$389 Roundtrip, found 1 day ago
$389
Roundtrip
found 1 day ago
Select United flight, departing Mon, Oct 19 from Santo Domingo to Buffalo, returning Wed, Nov 4, priced at $389 found 1 day ago
United
Mon, Oct 19 - Wed, Nov 4
SDQ
Santo Domingo
BUF
Buffalo
$395 Roundtrip, found 1 day ago
$395
Roundtrip
found 1 day ago
Select United flight, departing Mon, Oct 19 from Santo Domingo to Buffalo, returning Wed, Nov 4, priced at $395 found 1 day ago
United
Fri, Nov 20 - Mon, Nov 23
SDQ
Santo Domingo
BUF
Buffalo
$397 Roundtrip, found 17 hours ago
$397
Roundtrip
found 17 hours ago
Select United flight, departing Fri, Nov 20 from Santo Domingo to Buffalo, returning Mon, Nov 23, priced at $397 found 17 hours ago
United
Fri, Nov 20 - Mon, Nov 23
SDQ
Santo Domingo
BUF
Buffalo
$401 Roundtrip, found 17 hours ago
$401
Roundtrip
found 17 hours ago
Select United flight, departing Fri, Nov 20 from Santo Domingo to Buffalo, returning Mon, Nov 23, priced at $401 found 17 hours ago
American Airlines
Thu, Oct 29 - Thu, Nov 5
SDQ
Santo Domingo
BUF
Buffalo
$443 Roundtrip, found 1 day ago
$443
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Oct 29 from Santo Domingo to Buffalo, returning Thu, Nov 5, priced at $443 found 1 day ago
Delta
Thu, Oct 29 - Thu, Nov 5
SDQ
Santo Domingo
BUF
Buffalo
$445 Roundtrip, found 1 day ago
$445
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Oct 29 from Santo Domingo to Buffalo, returning Thu, Nov 5, priced at $445 found 1 day ago
JetBlue Airways
Fri, Oct 2 - Tue, Oct 6
SDQ
Santo Domingo
BUF
Buffalo
$487 Roundtrip, found 1 day ago
$487
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Fri, Oct 2 from Santo Domingo to Buffalo, returning Tue, Oct 6, priced at $487 found 1 day ago
Frontier Airlines
Fri, Dec 25 - Sun, Jan 3
SDQ
Santo Domingo
BUF
Buffalo
$1,224 Roundtrip, found 4 days ago
$1,224
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Fri, Dec 25 from Santo Domingo to Buffalo, returning Sun, Jan 3, priced at $1,224 found 4 days ago

What you need to know for your flight from Las Americas Intl. to Buffalo Niagara Intl.

Santo Domingo (SDQ) to Buffalo (BUF) at a glance

Embark on an international long-haul journey from Santo Domingo (SDQ) to Buffalo (BUF) with a selection of airlines catering to your needs. Whether you prefer full-service or budget-friendly options, you can compare various itineraries to find the perfect fit for your budget, schedule, and travel aspirations while discovering Buffalo's renowned attractions and neighborhoods. Discover essential flight information from Las Americas International Airport (SDQ) to Buffalo Niagara International Airport (BUF).

  • Fastest flight duration: around 5h 30m in-flight, plus roughly 3 hours layover with one stop
  • Route distance: roughly 1,800 miles (2,900 km)
  • Flights per week: around 8 departures on average
  • Typical fares (one-way): economy tickets often range from $185–$545, depending on seasonality and how far ahead you book

Flights from Las Americas International Airport (SDQ) to Buffalo Niagara International Airport (BUF)

Based on recent traveler bookings, here are the top airlines favored for flights from Santo Domingo to Buffalo, especially for one-stop and multi-stop journeys. Common layover points include John F. Kennedy International Airport (JFK) with an approximate 3-hour layover, Fort Lauderdale - Hollywood International Airport (FLL) with around 2 hours and 45 minutes, and Hartsfield-Jackson Atlanta International Airport (ATL) with about 3 hours and 30 minutes. These options allow you to balance price, total travel time, and cabin class to create your ideal travel itinerary.

  • JetBlue Airways: This budget-friendly airline provides one-stop service, with one-way ticket prices generally falling between $220 and $490. JetBlue handles about 44% of departures on this route, offering an in-flight duration of 5 hours and 30 minutes, leading to a total travel time of approximately 8 hours and 45 minutes when including the layover.
  • Delta: Known for its full-service offerings, Delta provides one-stop flights with one-way fares usually ranging from $185 to $630. It represents about 34% of departures on this route, with the flight time also being 5 hours and 30 minutes, resulting in a total journey time of around 8 hours and 45 minutes, accounting for the layover.
  • American Airlines: Offering a multi-stop service, this full-service airline typically charges between $190 and $400 for one-way tickets. American Airlines makes up roughly 16% of the departures on this route, featuring a flight duration of 6 hours and 45 minutes and a total travel time of about 10 hours, including layovers.
  • United: This full-service airline provides one-stop flights with one-way fares generally ranging from $230 to $330. United accounts for roughly 6% of departures on this route, with a flight time of 5 hours and 30 minutes and an overall journey time of approximately 8 hours and 45 minutes, including layover time.

Alternative routes from Santo Domingo (SDQ) to Buffalo (BUF)

  • Santo Domingo to Rochester (SDQ-ROC): Greater Rochester International Airport (ROC) is located approximately 56 miles from Buffalo Niagara International Airport (BUF). One-way economy fares for this journey generally fall between $200 and $475, influenced by the season and timing of your booking. Flights on this route often include both one-stop and multi-stop options, with common layover points at John F. Kennedy International Airport (JFK) and Newark Liberty International Airport (EWR). Major airlines operating on this route are JetBlue Airways (a budget carrier) and United.
  • Punta Cana to Buffalo (PUJ-BUF): Punta Cana International Airport (PUJ) is roughly 87 miles from Las Americas International Airport (SDQ). One-way economy prices on this route usually range from $170 to $605, varying based on the season and booking timing. This route offers both one-stop and multi-stop services, with popular layover locations being Charlotte-Douglas International Airport (CLT) and John F. Kennedy International Airport (JFK). Leading airlines on this route include American Airlines and JetBlue Airways (a low-cost option).

How to find the best prices for flights from Santo Domingo (SDQ) to Buffalo (BUF)

Getting some of the best deals on flights from Santo Domingo to Buffalo is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually found when booking 2-8 weeks in advance, coinciding with when most travelers make their reservations. Morning departures from 5 am to 12 pm tend to offer lower prices and are also the most popular flight times, while flying on Tuesday not only provides cheaper rates but is also the favored travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Buffalo Niagara International Airport from Las Americas International Airport

Buffalo welcomes travelers from Santo Domingo with a range of transport options based on price, convenience, and proximity. For departures, Las Americas International Airport is roughly a 25-minute drive (covering about 18 miles) from central Santo Domingo. Here's how to reach Buffalo efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Buffalo, with private rides that can be arranged in advance.
  • Car rental: Renting a car from Buffalo Niagara International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Buffalo Niagara International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Buffalo Niagara International Airport, Buffalo-Depew Station, a train station, is located about 2.6 miles away by car, while University Station, a metro station, is situated approximately 6.5 miles away by car, providing convenient options for onward travel.

Frequently asked questions

How much does a flight from Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) cost?
You can find cheap one-way flights from $239 and cheap return flights from $379 Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) with Expedia. One-way flights usually range from $240 to $896, and return flights typically cost between $483 and $1287. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The cheapest month to fly from SDQ to BUF is October when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Enter SDQ to BUF and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Frontier Airlines is one of the cheapest airlines offering connecting flights from Santo Domingo (SDQ) to Buffalo (BUF), with round-trip tickets starting from around $718. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
To find a cheap flight from Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The earliest flight from Las Americas International Airport (SDQ) to Buffalo Niagara International Airport (BUF) usually departs at around 12:55 AM, operated by JetBlue Airways. An early departure like this allows you to arrive in Buffalo with plenty of time to spare. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The most popular departure times for flights from Santo Domingo (SDQ) to Buffalo (BUF) are in the early morning, from 6am to 9am. About 38% of passengers prefer this time window. Many major carriers, including American Airlines, Delta, and JetBlue, offer flights during this window. This timing works well because it lets you start your day early and maximize your time in Buffalo.
How long does it take to fly from Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Flights from SDQ to BUF with one stop typically take around 9 hours 20 minutes, covering approximately 1,774 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Business class seats are offered on the SDQ to BUF route with Copa.
How do I earn miles on a Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight with Expedia?
It's easy to earn miles on a Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Buffalo from Las Americas Intl. (SDQ)?
From Las Americas Intl. (SDQ), you can fly into Buffalo Niagara Intl. (BUF) to reach Buffalo. Some flights may connect through major hubs like Miami Intl. (MIA), Liberty Intl. (EWR), Tocumen Intl. (PTY) before reaching Buffalo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) at the last minute?
Typically, booking a last minute flight from Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package?
Securing a Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) Buffalo Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
If you booked your Santo Domingo (SDQ-Las Americas Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Las Americas Intl.
Destination airport
Buffalo Niagara Intl.
Airlines serving
American Airlines, Delta, JetBlue Airways, United
Roundtrip price
$378
Distance
1773 mi

Book with confidence

Santo Domingo to Buffalo Flights

The cheapest times to fly from Santo Domingo to Buffalo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santo Domingo to Buffalo are during the month of October. You can find some of the cheapest flights from Santo Domingo to Buffalo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santo Domingo to Buffalo

Sunday is one of the best days to book for cheap flights from Santo Domingo to Buffalo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santo Domingo to Buffalo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santo Domingo to Buffalo in 2026. You can also book with separate airlines for your outbound and return journeys, from $239 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santo Domingo to Buffalo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santo Domingo to Buffalo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santo Domingo to Buffalo Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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