$583 Cheap Flights from Santo Domingo (SDQ) to Lyon (LYS)

View $583 flight on Mon, Oct 20, 2025Opens in a new window

Popular airlines from Las Americas Intl. Airport (SDQ) to Saint-Exupery Airport (LYS)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • one key icon

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Santo Domingo to Lyon (SDQ-LYS)

Prices were available within the past 7 days and start at $583 for one-way flights and $966 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Iberia
Tue, Nov 4 - Sun, Nov 23
SDQ
Santo Domingo
LYS
Lyon
$966 Roundtrip, found 3 days ago
$966
Roundtrip
found 3 days ago
Select Iberia flight, departing Tue, Nov 4 from Santo Domingo to Lyon, returning Sun, Nov 23, priced at $966 found 3 days ago
Iberia
Tue, Nov 4 - Sun, Nov 23
SDQ
Santo Domingo
LYS
Lyon
$974 Roundtrip, found 3 days ago
$974
Roundtrip
found 3 days ago
Select Iberia flight, departing Tue, Nov 4 from Santo Domingo to Lyon, returning Sun, Nov 23, priced at $974 found 3 days ago
Iberia
Tue, Nov 4 - Sun, Nov 23
SDQ
Santo Domingo
LYS
Lyon
$976 Roundtrip, found 3 days ago
$976
Roundtrip
found 3 days ago
Select Iberia flight, departing Tue, Nov 4 from Santo Domingo to Lyon, returning Sun, Nov 23, priced at $976 found 3 days ago
Iberia
Tue, Nov 4 - Sun, Nov 23
SDQ
Santo Domingo
LYS
Lyon
$985 Roundtrip, found 3 days ago
$985
Roundtrip
found 3 days ago
Select Iberia flight, departing Tue, Nov 4 from Santo Domingo to Lyon, returning Sun, Nov 23, priced at $985 found 3 days ago
Iberia
Fri, Nov 7 - Sun, Nov 23
SDQ
Santo Domingo
LYS
Lyon
$999 Roundtrip, found 3 days ago
$999
Roundtrip
found 3 days ago
Select Iberia flight, departing Fri, Nov 7 from Santo Domingo to Lyon, returning Sun, Nov 23, priced at $999 found 3 days ago
Iberia
Sun, Oct 12 - Sun, Nov 2
SDQ
Santo Domingo
LYS
Lyon
$1,001 Roundtrip, found 6 days ago
$1,001
Roundtrip
found 6 days ago
Select Iberia flight, departing Sun, Oct 12 from Santo Domingo to Lyon, returning Sun, Nov 2, priced at $1,001 found 6 days ago
United
Fri, Nov 14 - Sun, Nov 16
SDQ
Santo Domingo
LYS
Lyon
$1,105 Roundtrip, found 2 days ago
$1,105
Roundtrip
found 2 days ago
Select United flight, departing Fri, Nov 14 from Santo Domingo to Lyon, returning Sun, Nov 16, priced at $1,105 found 2 days ago
KLM
Thu, Oct 23 - Thu, Nov 6
SDQ
Santo Domingo
LYS
Lyon
$1,542 Roundtrip, found 4 days ago
$1,542
Roundtrip
found 4 days ago
Select KLM flight, departing Thu, Oct 23 from Santo Domingo to Lyon, returning Thu, Nov 6, priced at $1,542 found 4 days ago
Air France
Tue, Nov 4 - Sun, Nov 23
SDQ
Santo Domingo
LYS
Lyon
$1,709 Roundtrip, found 3 days ago
$1,709
Roundtrip
found 3 days ago
Select Air France flight, departing Tue, Nov 4 from Santo Domingo to Lyon, returning Sun, Nov 23, priced at $1,709 found 3 days ago
Turkish Airlines
Sun, Dec 21 - Sat, Jan 3
SDQ
Santo Domingo
LYS
Lyon
$2,009 Roundtrip, found 20 hours ago
$2,009
Roundtrip
found 20 hours ago
Select Turkish Airlines flight, departing Sun, Dec 21 from Santo Domingo to Lyon, returning Sat, Jan 3, priced at $2,009 found 20 hours ago

Frequently asked questions

How much does a flight from Las Americas Intl. Airport (SDQ) to Saint-Exupery Airport (LYS) cost?
Get a cheap one-way flight from $583 or cheap return flight from $966 from Las Americas Intl. Airport (SDQ) to Saint-Exupery Airport (LYS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Las Americas Intl. Airport (SDQ) to Saint-Exupery Airport (LYS)?
November is the cheapest month to fly from SDQ to LYS. Avoiding peak travel times is often the key to scoring lower fares.
What is the cheapest airline that flies from Las Americas Intl. Airport (SDQ) to Saint-Exupery Airport (LYS)?
Use the filter tool on Expedia to compare airlines and find the most affordable carrier that'll fly you from SDQ to LYS. Then, sort your results by "Price (lowest to highest)" to snag a good deal.
How many flights per day from Las Americas Intl. Airport (SDQ) to Saint-Exupery Airport (LYS)?
You'll have to hop on a flight with a layover if you're traveling from Las Americas Intl. Airport (SDQ) to Saint-Exupery Airport (LYS). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to discover an option that works for you.
What day of the week has the most flights from SDQ to LYS?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Las Americas Intl. Airport (SDQ) to Saint-Exupery Airport (LYS)?
Opt for a flight from Las Americas Intl. Airport (SDQ) to Saint-Exupery Airport (LYS) that leaves before 3 PM to reduce the risk of cancellations and delays. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Las Americas Intl. Airport (SDQ) to Saint-Exupery Airport (LYS) last-minute?
Holding off until right before your break to book a flight from SDQ to LYS generally means paying more. While it's possible to find some last-minute discounts, they're not always guaranteed. Be flexible with your itinerary to maximize your chances of snagging a bargain.
Is it cheaper to book a SDQ to LYS flight and hotel package?
You'll generally save money by booking a SDQ to LYS flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one place. After selecting your ideal flights and accommodations, consider adding extras including activities, tours and car rentals.
Can I cancel or change the date of my flight from Las Americas Intl. Airport (SDQ) to Saint-Exupery Airport (LYS)?
Generally, it's possible to reschedule or cancel your SDQ to LYS flight. However, if it's been more than 24 hours since booking, additional fees may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Travel information

Origin airport
Las Americas Intl.
Destination airport
Saint-Exupery
Airlines serving
Aeromexico, Air France, American Airlines, Delta, Iberia, KLM, Turkish Airlines, United
Roundtrip price
$965
Distance
4586 mi

Book with confidence

Book with confidence

Santo Domingo to Lyon Flights

The cheapest times to fly from Santo Domingo to Lyon

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santo Domingo to Lyon are during the month of November. You can find some of the cheapest flights from Santo Domingo to Lyon with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santo Domingo to Lyon

Sunday is one of the best days to book for cheap flights from Santo Domingo to Lyon: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santo Domingo to Lyon

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santo Domingo to Lyon in 2025. You can also book with separate airlines for your outbound and return journeys, from $583 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santo Domingo to Lyon flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santo Domingo to Lyon airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santo Domingo to Lyon Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.