--- title: "Syracuse to Florence cheap flights from $247 (SYR to FLO) - Expedia" description: "Book cheap Flights from Syracuse (SYR) to Florence (FLO) start at $247 for one-way and $481 for round trip. Earn your airline miles on top of our rewards!" canonical: "https://www.expedia.com/lp/flights/syr/flo/syracuse-to-florence" language: en-US market: US currency: USD prices_as_of: 2026-11-13T09:19:10Z --- # $247 Cheap Flights from Syracuse (SYR) to Florence (FLO) ![A shopping mall with a Magnolia Mall sign and a Burlington store across the street.](https://images.trvl-media.com/place/6165602/4392990f-7038-4d9a-a654-83ae3a3dcd0f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) [View $247 flight on Tue, Mar 30, 2027](https://www.expedia.com/Flights-Search?leg1=from:SYR,to:FLO,departure:3/30/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:246.20&airProductToken=AQpoCjIIwYIBEgM0OTgYko4BIOKaASiJjKkDMIqNqQM4QkAAWAFqBUJBU0lDcghPV0FYS05CWgoyCMGCARIENTk4NBjimgEg5XIov42pAzD-jakDOEJAAVgBagVCQVNJQ3IIT1dBWEtOQloSDAgBEAEYASoCQUEyABgBIgQIARABKAIoAygEMAs) ## Popular airlines from Hancock Intl. Airport (SYR) to Florence, SC (FLO-Florence Regional) [American Airlines](https://www.expedia.com/Flights-Search?leg1=from:SYR,to:FLO,departure:11/27/2026TANYT&leg2=from:FLO,to:SYR,departure:12/4/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) ### Be in the know Get alerts if flight prices drop or rise\* ### Book smarter Save up to 30% on select hotels after you book a flight\* ### Earn twice Earn your airline miles on top of our OneKeyCash [Learn about One Key](https://www.expedia.com/welcome-one-key) ## Cheap Flights from Syracuse to Florence (SYR-FLO) Prices were available within the past 7 days and start at $247 for one-way flights and $481 for roundtrip, for the period specified. Prices and availability are subject to change. All deals One way Roundtrip [Select American Airlines flight, departing Fri, Jan 22 from Syracuse to Florence, returning Sun, Jan 24, priced at $481 Found 10 hours ago](https://www.expedia.com/Flights-Search?leg1=from:SYR,to:FLO,departure:1/22/2027TANYT&leg2=from:FLO,to:SYR,departure:1/24/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:480.40&airProductToken=AQpnCjIIwYIBEgQyNzM3GJKOASDimgEopp2jAzC2nqMDOE9AAFgBagRNQUlOcghPV0ZXWlNNMwoxCMGCARIENTg5MxjimgEg5XIo75-jAzCvoKMDOE9AAVgBagRNQUlOcghPV0ZXWlNNMwpnCjEIwYIBEgQ1ODM4GOVyIOKaASiKr6MDMNSvowM4T0AAWAFqBE1BSU5yCE9XRldaU00zCjIIwYIBEgQyNTk4GOKaASCSjgEoh7GjAzDzsaMDOE9AAVgBagRNQUlOcghPV0ZXWlNNMxIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAE) Fri, Jan 22 - Sun, Jan 24 · SYR · FLO · Roundtrip [Select American Airlines flight, departing Fri, Jan 22 from Syracuse to Florence, returning Sun, Jan 24, priced at $549 Found 10 hours ago](https://www.expedia.com/Flights-Search?leg1=from:SYR,to:FLO,departure:1/22/2027TANYT&leg2=from:FLO,to:SYR,departure:1/24/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:548.40&airProductToken=AQprCjQIwYIBEgQyNzM3GJKOASDimgEopp2jAzC2nqMDOE9AAFgBagZNQUlORkxyCE9XRldaUlYzCjMIwYIBEgQ1ODkzGOKaASDlcijvn6MDMK-gowM4T0ABWAFqBk1BSU5GTHIIT1dGV1pSVjMKawozCMGCARIENTgzOBjlciDimgEoiq-jAzDUr6MDOE9AAFgBagZNQUlORkxyCE9XRldaUlYzCjQIwYIBEgQyNTk4GOKaASCSjgEoh7GjAzDzsaMDOE9AAVgBagZNQUlORkxyCE9XRldaUlYzEgoIARABGAEqAkFBGAEiBAgBEAEoAigEKAYwAQ) Fri, Jan 22 - Sun, Jan 24 · SYR · FLO · Roundtrip [Select American Airlines flight, departing Sun, Nov 22 from Syracuse to Florence, returning Tue, Dec 1, priced at $557 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:SYR,to:FLO,departure:11/22/2026TANYT&leg2=from:FLO,to:SYR,departure:12/1/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:556.40&airProductToken=AQpnCjIIwYIBEgQyNTk4GJKOASDimgEoje-dAzCc8J0DOFFAAFgBagRNQUlOcghRMEFYWk5OMQoxCMGCARIENTg5MxjimgEg5XIohvKdAzDG8p0DOFFAAVgBagRNQUlOcghRMEFYWk5OMRIMCAEQARgBKgJBQTIAGAEiBAgBEAEoAigDKAQwCw) Sun, Nov 22 - Tue, Dec 1 · SYR · FLO · Roundtrip [Select American Airlines flight, departing Sun, Nov 22 from Syracuse to Florence, returning Tue, Dec 1, priced at $565 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:SYR,to:FLO,departure:11/22/2026TANYT&leg2=from:FLO,to:SYR,departure:12/1/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:564.40&airProductToken=AQpnCjIIwYIBEgQyNTk4GJKOASDimgEoje-dAzCc8J0DOFFAAFgBagRNQUlOcghRMEZXWk5OMQoxCMGCARIENTg5MxjimgEg5XIohvKdAzDG8p0DOFFAAVgBagRNQUlOcghRMEZXWk5OMQpnCjEIwYIBEgQ1OTg0GOVyIOKaASi3054DMPrTngM4UUAAWAFqBE1BSU5yCFEwRldaTk4xCjIIwYIBEgQzMjc4GOKaASCSjgEovNSeAzCs1Z4DOFFAAVgBagRNQUlOcghRMEZXWk5OMRIMCAEQARgBKgJBQTIAGAEiBAgBEAEoAigDKAQwCw) Sun, Nov 22 - Tue, Dec 1 · SYR · FLO · Roundtrip [Select American Airlines flight, departing Sun, Nov 22 from Syracuse to Florence, returning Tue, Dec 1, priced at $570 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:SYR,to:FLO,departure:11/22/2026TANYT&leg2=from:FLO,to:SYR,departure:12/1/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:569.40&airProductToken=AQpnCjIIwYIBEgQyNTk4GJKOASDimgEoje-dAzCc8J0DOFFAAFgBagRNQUlOcghRMEZXWk5OMQoxCMGCARIENTg5MxjimgEg5XIohvKdAzDG8p0DOFFAAVgBagRNQUlOcghRMEZXWk5OMQpnCjEIwYIBEgQ1ODM4GOVyIOKaASiBz54DMMLPngM4TkAAWAFqBE1BSU5yCE4wQVhLTk4xCjIIwYIBEgQyMzM5GOKaASCSjgEo6NCeAzDV0Z4DOE5AAVgBagRNQUlOcghOMEFYS05OMRIMCAEQARgBKgJBQTIAGAEiBAgBEAEoAigDKAQwCw) Sun, Nov 22 - Tue, Dec 1 · SYR · FLO · Roundtrip [Select American Airlines flight, departing Sun, Nov 22 from Syracuse to Florence, returning Tue, Dec 1, priced at $575 Found 9 hours ago](https://www.expedia.com/Flights-Search?leg1=from:SYR,to:FLO,departure:11/22/2026TANYT&leg2=from:FLO,to:SYR,departure:12/1/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:574.40&airProductToken=AQpnCjIIwYIBEgQyNTk4GJKOASDimgEoje-dAzCc8J0DOFFAAFgBagRNQUlOcghRMEZXWk5OMQoxCMGCARIENTg5MxjimgEg5XIohvKdAzDG8p0DOFFAAVgBagRNQUlOcghRMEZXWk5OMQpnCjEIwYIBEgQ1OTg0GOVyIOKaASi3054DMPrTngM4UUAAWAFqBE1BSU5yCFEwRldaTk4xCjIIwYIBEgQzMjc4GOKaASCSjgEovNSeAzCs1Z4DOFFAAVgBagRNQUlOcghRMEZXWk5OMRIMCAEQARgBKgJBQTIAGAEiBAgBEAEoAigDKAQwAQ) Sun, Nov 22 - Tue, Dec 1 · SYR · FLO · Roundtrip [Select American Airlines flight, departing Sun, Nov 22 from Syracuse to Florence, returning Tue, Dec 1, priced at $586 Found 2 days ago](https://www.expedia.com/Flights-Search?leg1=from:SYR,to:FLO,departure:11/22/2026TANYT&leg2=from:FLO,to:SYR,departure:12/1/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:585.41&airProductToken=AQpnCjIIwYIBEgQyNTk4GJKOASDimgEoje-dAzCc8J0DOFFAAFgBagRNQUlOcghRMEZXWk5OMQoxCMGCARIENTg5MxjimgEg5XIohvKdAzDG8p0DOFFAAVgBagRNQUlOcghRMEZXWk5OMQpnCjEIwYIBEgQ1ODM4GOVyIOKaASiBz54DMMLPngM4R0AAWAFqBE1BSU5yCEcwRldVTk4xCjIIwYIBEgQyMzM5GOKaASCSjgEo6NCeAzDV0Z4DOEdAAVgBagRNQUlOcghHMEZXVU5OMRIMCAEQARgBKgJBQTIAGAEiBAgBEAEoAigDKAQwCw) Sun, Nov 22 - Tue, Dec 1 · SYR · FLO · Roundtrip [Select American Airlines flight, departing Sun, Nov 22 from Syracuse to Florence, returning Tue, Dec 1, priced at $596 Found 9 hours ago](https://www.expedia.com/Flights-Search?leg1=from:SYR,to:FLO,departure:11/22/2026TANYT&leg2=from:FLO,to:SYR,departure:12/1/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:595.40&airProductToken=AQpnCjIIwYIBEgQzMjc4GJKOASDimgEovvCdAzDP8Z0DOFFAAFgBagRNQUlOcghRMEZXWk5OMQoxCMGCARIENTg5MxjimgEg5XIohvKdAzDG8p0DOFFAAVgBagRNQUlOcghRMEZXWk5OMQpnCjEIwYIBEgQ1ODM4GOVyIOKaASiBz54DMMLPngM4R0AAWAFqBE1BSU5yCEcwRldVTk4xCjIIwYIBEgQyMzM5GOKaASCSjgEo6NCeAzDV0Z4DOEdAAVgBagRNQUlOcghHMEZXVU5OMRIMCAEQARgBKgJBQTIAGAEiBAgBEAEoAigDKAQwAQ) Sun, Nov 22 - Tue, Dec 1 · SYR · FLO · Roundtrip [Select American Airlines flight, departing Sun, Nov 22 from Syracuse to Florence, returning Tue, Dec 1, priced at $611 Found 4 days ago](https://www.expedia.com/Flights-Search?leg1=from:SYR,to:FLO,departure:11/22/2026TANYT&leg2=from:FLO,to:SYR,departure:12/1/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:610.40&airProductToken=AQpnCjIIwYIBEgQzMjc4GJKOASDimgEovvCdAzDP8Z0DOFFAAFgBagRNQUlOcghRMEZXWk5OMQoxCMGCARIENTg5MxjimgEg5XIohvKdAzDG8p0DOFFAAVgBagRNQUlOcghRMEZXWk5OMQpnCjEIwYIBEgQ1ODM4GOVyIOKaASiBz54DMMLPngM4VkAAWAFqBE1BSU5yCFYwRldVTk4xCjIIwYIBEgQyMzM5GOKaASCSjgEo6NCeAzDV0Z4DOFZAAVgBagRNQUlOcghWMEZXVU5OMRIMCAEQARgBKgJBQTIAGAEiBAgBEAEoAigDKAQwCw) Sun, Nov 22 - Tue, Dec 1 · SYR · FLO · Roundtrip [Select American Airlines flight, departing Fri, Jan 22 from Syracuse to Florence, returning Sun, Jan 24, priced at $617 Found 10 hours ago](https://www.expedia.com/Flights-Search?leg1=from:SYR,to:FLO,departure:1/22/2027TANYT&leg2=from:FLO,to:SYR,departure:1/24/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:616.40&airProductToken=AQprCjQIwYIBEgQyNzM3GJKOASDimgEopp2jAzC2nqMDOE9AAFgBagZNQUlOUExyCE9XRldaU1QzCjMIwYIBEgQ1ODkzGOKaASDlcijvn6MDMK-gowM4T0ABWAFqBk1BSU5QTHIIT1dGV1pTVDMKawozCMGCARIENTgzOBjlciDimgEoiq-jAzDUr6MDOE9AAFgBagZNQUlOUExyCE9XRldaU1QzCjQIwYIBEgQyNTk4GOKaASCSjgEoh7GjAzDzsaMDOE9AAVgBagZNQUlOUExyCE9XRldaU1QzEgoIAhABGAIqAkFBGAEiBAgBEAEoAigDKAQwAQ) Fri, Jan 22 - Sun, Jan 24 · SYR · FLO · Roundtrip ## Book with confidence ### Syracuse to Florence Flights #### The cheapest times to fly from Syracuse to Florence On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Syracuse to Florence are during the month of January. You can find some of the cheapest flights from Syracuse to Florence with Expedia's search tool and vast selection of airlines. #### The best time to book a flight from Syracuse to Florence Sunday is one of the best days to book for cheap flights from Syracuse to Florence: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance. #### How to find cheap round-trip tickets from Syracuse to Florence Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Syracuse to Florence in 2026\. You can also book with separate airlines for your outbound and return journeys, from $247 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference\*. This is available for a small fee, and is free to One Key Gold and Platinum tier members. Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Syracuse to Florence flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps. You could also save big by booking one of Expedia's [vacation packages](https://www.expedia.com/package-deals). Bundling together your Syracuse to Florence airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures. *\*Terms apply.* *Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023\. The percentages you see are averages.* ## Frequently Asked Questions ### How much does a flight from Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional) cost? You can find cheap one-way flights from $247 and cheap return flights $481 Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional) with Expedia. One-way flights typically cost between $256 and $557, and return flights often range between $468 and $1163\. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional) ticket fares go up or down. *\*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.* ### What is the cheapest month to fly from Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional)? The cheapest month to fly from SYR to FLO is January when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route. ### Which airlines fly direct from Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional)? Enter SYR to FLO and your travel dates, then apply the 'Nonstop' filter to see only direct flights. ### What is the cheapest airline that flies from Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional)? American Airlines is one of the cheapest airlines offering connecting flights from Syracuse (SYR) to Florence (FLO) with a layover in Philadelphia Intl. (PHL), starting from around $468\. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget. *\*Prices based on flights available on Expedia in the last year.* ### How do I find cheap flights from Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional)? To find a cheap flight from Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up [Price Tracking](https://www.expedia.com/why/price-tracking) and receive alerts when fares go up or down. ### What is the best time to fly from Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional)? The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience. ### What is the earliest flight from Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional)? The earliest flight from Hancock Intl. (SYR) to Florence Regional (FLO) generally departs at around 5:10 AM, operated by American Airlines. This seasonal service is available in June, giving you an early start to explore Florence. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search. ### What are the most popular departure times for flights from Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional)? The most popular departure times for flights from Hancock Intl. (SYR) to Florence Regional (FLO) are from 6am to 9am. About 44% of passengers prefer this time window. Many major carriers, including American Airlines, offer flights during this window. This timing works well because it allows you to travel early and arrive in Florence with plenty of time to explore. ### How long does it take to fly from Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional)? A flight from SYR to FLO with a layover takes around 4 hours 20 minutes, with the route covering approximately 646 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic. ### Can you fly business or first class from Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional)? Select the "Business class" and "First class" filters when looking for SYR to FLO flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip. ### How do I earn miles on a Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional) flight with Expedia? It's easy to earn miles on a Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of [One Key™](https://www.expedia.com/welcome-one-key), you can also earn OneKeyCash™\* on top of your airline miles when you book with Expedia. \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands. ### What airports do you fly into for Florence from Hancock Intl. (SYR)? From Hancock Intl. (SYR), you can fly into Florence Regional (FLO) and Peretola (FLR) in Florence. Some flights may connect through major hubs like Philadelphia Intl. (PHL), Ronald Reagan Washington National (DCA), O'Hare Intl. (ORD) before reaching Florence. Compare routes and airports on Expedia to find the best flight options for your travel plans. ### Is it cheaper to buy a plane ticket from Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional) at the last minute? Typically, booking a last minute flight from Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare. ### Is it cheaper to book a Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional) flight and hotel package? Securing a Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars. ### Can I cancel or change the date of my flight from Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional)? If you booked your Syracuse, NY (SYR-Hancock Intl.) to Florence, SC (FLO-Florence Regional) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in [your itinerary](https://www.expedia.com/trips) or confirmation email. Or, head to our [Customer Service portal](https://www.expedia.com/helpcenter/) if you'd like more information. ## Travel information | Origin airport | Hancock Intl. Airport | | ------------------- | --------------------- | | Destination airport | Florence, SC | | Distance | 646 miles away | | Airlines serving | American Airlines | | Popular airline | American Airlines | | Roundtrip price | $481 | ## Explore a world of travel with Expedia - [Flights](?equalTargetTab=tab-0) - [Flights from Sacramento (SMF) to Florence (FLO)](https://www.expedia.com/lp/flights/smf/flo/sacramento-to-florence) - [Flights from Lexington (LEX) to Florence (FLO)](https://www.expedia.com/lp/flights/lex/flo/lexington-to-florence) - [Flights from Evansville (EVV) to Florence (FLO)](https://www.expedia.com/lp/flights/evv/flo/evansville-to-florence) - [Flights from Hartford (BDL) to Florence (FLO)](https://www.expedia.com/lp/flights/bdl/flo/hartford-to-florence) - [Flights from Boston (BOS) to Myrtle Beach (MYR)](https://www.expedia.com/lp/flights/bos/myr/boston-to-myrtle-beach) - [Flights from Appleton (ATW) to Florence (FLO)](https://www.expedia.com/lp/flights/atw/flo/appleton-to-florence) - [Flights from Myrtle Beach (MYR) to Florence (FLO)](https://www.expedia.com/lp/flights/myr/flo/myrtle-beach-to-florence) - [Flights from Little Rock (LIT) to Florence (FLO)](https://www.expedia.com/lp/flights/lit/flo/little-rock-to-florence) - [Flights from New Orleans (MSY) to Florence (FLO)](https://www.expedia.com/lp/flights/msy/flo/new-orleans-to-florence) - [Flights from Gainesville (GNV) to Florence (FLO)](https://www.expedia.com/lp/flights/gnv/flo/gainesville-to-florence) - [Flights from San Francisco (SFO) to Florence (FLO)](https://www.expedia.com/lp/flights/sfo/flo/san-francisco-to-florence) - [Flights from Indianapolis (IND) to Florence (FLO)](https://www.expedia.com/lp/flights/ind/flo/indianapolis-to-florence) - [Flights from Jacksonville (JAX) to Florence (FLO)](https://www.expedia.com/lp/flights/jax/flo/jacksonville-to-florence) - [Flights from Tucson (TUS) to Florence (FLO)](https://www.expedia.com/lp/flights/tus/flo/tucson-to-florence) - [Flights from Seattle (SEA) to Florence (FLO)](https://www.expedia.com/lp/flights/sea/flo/seattle-to-florence) - [Flights from Greensboro (GSO) to Florence (FLO)](https://www.expedia.com/lp/flights/gso/flo/greensboro-to-florence) - [Flights from Miami (MIA) to Florence (FLO)](https://www.expedia.com/lp/flights/mia/flo/miami-to-florence) - [Flights from Allentown (ABE) to Florence (FLO)](https://www.expedia.com/lp/flights/abe/flo/allentown-to-florence) - [Flights from Eugene (EUG) to Florence (FLO)](https://www.expedia.com/lp/flights/eug/flo/eugene-to-florence) - [Flights from Kansas City (MCI) to Florence (FLO)](https://www.expedia.com/lp/flights/mci/flo/kansas-city-to-florence) - [Flights from Columbus (CMH) to Florence (FLO)](https://www.expedia.com/lp/flights/cmh/flo/columbus-to-florence) - [Flights from Denver (DEN) to Florence (FLO)](https://www.expedia.com/lp/flights/den/flo/denver-to-florence) - [Flights from Salt Lake City (SLC) to Florence (FLO)](https://www.expedia.com/lp/flights/slc/flo/salt-lake-city-to-florence) - [Flights from Sarasota (SRQ) to Florence (FLO)](https://www.expedia.com/lp/flights/srq/flo/sarasota-to-florence) - [Flights from Fort Myers (RSW) to Florence (FLO)](https://www.expedia.com/lp/flights/rsw/flo/fort-myers-to-florence) - [Flights from Latrobe (LBE) to Florence (FLO)](https://www.expedia.com/lp/flights/lbe/flo/latrobe-to-florence) - [Flights from Wilmington (ILM) to Florence (FLO)](https://www.expedia.com/lp/flights/ilm/flo/wilmington-to-florence) - [Flights from San Diego (SAN) to Florence (FLO)](https://www.expedia.com/lp/flights/san/flo/san-diego-to-florence) - [Flights from Rochester (ROC) to Florence (FLO)](https://www.expedia.com/lp/flights/roc/flo/rochester-to-florence) - [Flights from Oklahoma City (OKC) to Florence (FLO)](https://www.expedia.com/lp/flights/okc/flo/oklahoma-city-to-florence) - [Flights from Birmingham (BHM) to Florence (FLO)](https://www.expedia.com/lp/flights/bhm/flo/birmingham-to-florence) - [Flights from Minneapolis (MSP) to Florence (FLO)](https://www.expedia.com/lp/flights/msp/flo/minneapolis-to-florence) - [Flights from Asheville (AVL) to Florence (FLO)](https://www.expedia.com/lp/flights/avl/flo/asheville-to-florence) - [Flights from Augusta (AGS) to Florence (FLO)](https://www.expedia.com/lp/flights/ags/flo/augusta-to-florence) - [Flights from Albany (ALB) to Florence (FLO)](https://www.expedia.com/lp/flights/alb/flo/albany-to-florence) - [Flights from Orlando (MCO) to Florence (FLO)](https://www.expedia.com/lp/flights/mco/flo/orlando-to-florence) - [Flights from Mobile (MOB) to Florence (FLO)](https://www.expedia.com/lp/flights/mob/flo/mobile-to-florence) - [Flights from Phoenix (PHX) to Florence (FLO)](https://www.expedia.com/lp/flights/phx/flo/phoenix-to-florence) - [Flights from New York (LGA) to Florence (FLO)](https://www.expedia.com/lp/flights/lga/flo/new-york-to-florence) - [Flights from Huntsville (HSV) to Florence (FLO)](https://www.expedia.com/lp/flights/hsv/flo/huntsville-to-florence) - [Flights from Newark Liberty Intl. Airport (EWR) to Florence (FLO)](https://www.expedia.com/lp/flights/ewr/flo/newark-liberty-intl-airport-to-florence) - [Flights from Dayton (DAY) to Florence (FLO)](https://www.expedia.com/lp/flights/day/flo/dayton-to-florence) - [Flights from Milwaukee (MKE) to Florence (FLO)](https://www.expedia.com/lp/flights/mke/flo/milwaukee-to-florence) - [Flights from Fayetteville (XNA) to Florence (FLO)](https://www.expedia.com/lp/flights/xna/flo/fayetteville-to-florence) - [Flights from Atlanta (ATL) to Florence (FLO)](https://www.expedia.com/lp/flights/atl/flo/atlanta-to-florence) - [Flights from Missoula (MSO) to Florence (FLO)](https://www.expedia.com/lp/flights/mso/flo/missoula-to-florence) - [Flights from South Bend (SBN) to Florence (FLO)](https://www.expedia.com/lp/flights/sbn/flo/south-bend-to-florence) - [Flights from Nairobi (NBO) to Florence (FLO)](https://www.expedia.com/lp/flights/nbo/flo/nairobi-to-florence) - [Flights from Boston (BOS) to Florence (FLO)](https://www.expedia.com/lp/flights/bos/flo/boston-to-florence) - [Flights from Charlotte (CLT) to Florence (FLO)](https://www.expedia.com/lp/flights/clt/flo/charlotte-to-florence) - [Flights from Washington (DCA) to Florence (FLO)](https://www.expedia.com/lp/flights/dca/flo/washington-to-florence) - [Flights from Los Angeles (LAX) to Florence (FLO)](https://www.expedia.com/lp/flights/lax/flo/los-angeles-to-florence) - [Flights from Cleveland (CLE) to Florence (FLO)](https://www.expedia.com/lp/flights/cle/flo/cleveland-to-florence) - [Flights from San Antonio (SAT) to Florence (FLO)](https://www.expedia.com/lp/flights/sat/flo/san-antonio-to-florence) - [Flights from Washington (IAD) to Florence (FLO)](https://www.expedia.com/lp/flights/iad/flo/washington-to-florence) - [Flights from West Palm Beach (PBI) to Florence (FLO)](https://www.expedia.com/lp/flights/pbi/flo/west-palm-beach-to-florence) - [Flights from Pittsburgh (PIT) to Florence (FLO)](https://www.expedia.com/lp/flights/pit/flo/pittsburgh-to-florence) - [Flights from Louisville (SDF) to Florence (FLO)](https://www.expedia.com/lp/flights/sdf/flo/louisville-to-florence) - [Flights from Knoxville (TYS) to Florence (FLO)](https://www.expedia.com/lp/flights/tys/flo/knoxville-to-florence) - [Flights from St. Louis (STL) to Florence (FLO)](https://www.expedia.com/lp/flights/stl/flo/st-louis-to-florence) - [Flights from Chattanooga (CHA) to Florence (FLO)](https://www.expedia.com/lp/flights/cha/flo/chattanooga-to-florence) - [Flights from Baltimore (BWI) to Florence (FLO)](https://www.expedia.com/lp/flights/bwi/flo/baltimore-to-florence) - [Flights from Colorado Springs (COS) to Florence (FLO)](https://www.expedia.com/lp/flights/cos/flo/colorado-springs-to-florence) - [Flights from New York (NYC) to Florence (FLO)](https://www.expedia.com/lp/flights/nyc/flo/new-york-to-florence) - [Flights from Savannah (SAV) to Florence (FLO)](https://www.expedia.com/lp/flights/sav/flo/savannah-to-florence) - [Flights from Tulsa (TUL) to Florence (FLO)](https://www.expedia.com/lp/flights/tul/flo/tulsa-to-florence) - [Flights from New York (JFK) to Florence (FLO)](https://www.expedia.com/lp/flights/jfk/flo/new-york-to-florence) - [Flights from Norfolk (ORF) to Florence (FLO)](https://www.expedia.com/lp/flights/orf/flo/norfolk-to-florence) - [Flights from Buffalo (BUF) to Florence (FLO)](https://www.expedia.com/lp/flights/buf/flo/buffalo-to-florence) - [Flights from Richmond (RIC) to Florence (FLO)](https://www.expedia.com/lp/flights/ric/flo/richmond-to-florence) - [Flights from Columbia (CAE) to Florence (FLO)](https://www.expedia.com/lp/flights/cae/flo/columbia-to-florence) - [Flights from Fort Lauderdale (FLL) to Florence (FLO)](https://www.expedia.com/lp/flights/fll/flo/fort-lauderdale-to-florence) - [Flights from Greenville (GSP) to Florence (FLO)](https://www.expedia.com/lp/flights/gsp/flo/greenville-to-florence) - [Flights from Memphis (MEM) to Florence (FLO)](https://www.expedia.com/lp/flights/mem/flo/memphis-to-florence) - [Flights from Detroit (DTW) to Florence (FLO)](https://www.expedia.com/lp/flights/dtw/flo/detroit-to-florence) - [Flights from Austin (AUS) to Florence (FLO)](https://www.expedia.com/lp/flights/aus/flo/austin-to-florence) - [Flights from Rzeszow (RZE) to Florence (FLO)](https://www.expedia.com/lp/flights/rze/flo/rzeszow-to-florence) - [Flights from Tampa (TPA) to Florence (FLO)](https://www.expedia.com/lp/flights/tpa/flo/tampa-to-florence) - [Flights from Cincinnati (CVG) to Florence (FLO)](https://www.expedia.com/lp/flights/cvg/flo/cincinnati-to-florence) - [Flights from Dothan (DHN) to Florence (FLO)](https://www.expedia.com/lp/flights/dhn/flo/dothan-to-florence) - [Flights from San Luis Obispo (SBP) to Florence (FLO)](https://www.expedia.com/lp/flights/sbp/flo/san-luis-obispo-to-florence) - [Flights from Houston (IAH) to Florence (FLO)](https://www.expedia.com/lp/flights/iah/flo/houston-to-florence) - [Flights from Providence (PVD) to Florence (FLO)](https://www.expedia.com/lp/flights/pvd/flo/providence-to-florence) - [Flights from Pensacola (PNS) to Florence (FLO)](https://www.expedia.com/lp/flights/pns/flo/pensacola-to-florence) - [Flights from Nashville (BNA) to Florence (FLO)](https://www.expedia.com/lp/flights/bna/flo/nashville-to-florence) - [Flights from Charleston (CHS) to Florence (FLO)](https://www.expedia.com/lp/flights/chs/flo/charleston-to-florence) - [Flights from Fort Walton Beach (VPS) to Florence (FLO)](https://www.expedia.com/lp/flights/vps/flo/fort-walton-beach-to-florence) - [Flights from Dallas (DFW) to Florence (FLO)](https://www.expedia.com/lp/flights/dfw/flo/dallas-to-florence) - [Flights from Anchorage (ANC) to Florence (FLO)](https://www.expedia.com/lp/flights/anc/flo/anchorage-to-florence) - [Flights from Philadelphia (PHL) to Florence (FLO)](https://www.expedia.com/lp/flights/phl/flo/philadelphia-to-florence) - [Flights from Las Vegas (LAS) to Florence (FLO)](https://www.expedia.com/lp/flights/las/flo/las-vegas-to-florence) - [Flights from New Haven (HVN) to Florence (FLO)](https://www.expedia.com/lp/flights/hvn/flo/new-haven-to-florence) - [Flights from Portland (PDX) to Florence (FLO)](https://www.expedia.com/lp/flights/pdx/flo/portland-to-florence) - [Flights from El Paso (ELP) to Florence (FLO)](https://www.expedia.com/lp/flights/elp/flo/el-paso-to-florence) - [Flights from Newburgh (SWF) to Florence (FLO)](https://www.expedia.com/lp/flights/swf/flo/newburgh-to-florence) - [Flights from Lancaster (LNS) to Florence (FLO)](https://www.expedia.com/lp/flights/lns/flo/lancaster-to-florence) - [Flights from Fresno (FAT) to Florence (FLO)](https://www.expedia.com/lp/flights/fat/flo/fresno-to-florence) - [Flights from Tallahassee (TLH) to Florence (FLO)](https://www.expedia.com/lp/flights/tlh/flo/tallahassee-to-florence) - [Flights from London (LHR) to Florence (FLO)](https://www.expedia.com/lp/flights/lhr/flo/london-to-florence) - [Flights from Chicago (ORD) to Florence (FLO)](https://www.expedia.com/lp/flights/ord/flo/chicago-to-florence) \*Available to One Key members. ## Other language versions ```yaml hreflang: x-default: https://www.expedia.com/lp/flights/syr/flo/syracuse-to-florence es: https://www.expedia.com/es/lp/vuelos/syr/flo/siracusa-a-florence ar: https://www.expedia.sa/lp/flights/syr/flo/syracuse-to-florence en-US: https://www.expedia.com/lp/flights/syr/flo/syracuse-to-florence ```