A city skyline with a prominent arch bridge at sunset.

Popular airlines from Tucson International Airport (TUS) to St. Louis Lambert Intl. Airport (STL)

Be in the know
Get alerts if flight prices drop or rise*
Book smarter
Save up to 30% on select hotels after you book a flight*
Earn twice
Earn your airline miles on top of our OneKeyCash
Learn about One Key

Cheap Flights from Tucson to St. Louis (TUS-STL)

Prices were available within the past 7 days and start at $199 for one-way flights and $367 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

All deals

One way

Roundtrip

Wed, Nov 18 - Tue, Dec 1

TUS

Tucson

STL

St. Louis

$367

Roundtrip

found 2 days ago

Wed, Nov 18 - Tue, Dec 1

TUS

Tucson

STL

St. Louis

$368

Roundtrip

found 2 days ago

Wed, Nov 18 - Tue, Dec 1

TUS

Tucson

STL

St. Louis

$381

Roundtrip

found 2 days ago

Tue, Nov 17 - Fri, Nov 27

TUS

Tucson

STL

St. Louis

$394

Roundtrip

found 2 days ago

Tue, Oct 20 - Tue, Oct 27

TUS

Tucson

STL

St. Louis

$397

Roundtrip

just found

Tue, Oct 27 - Tue, Dec 8

TUS

Tucson

STL

St. Louis

$399

Roundtrip

found 1 day ago

Wed, Nov 25 - Tue, Dec 1

TUS

Tucson

STL

St. Louis

$400

Roundtrip

found 12 hours ago

Wed, Oct 14 - Wed, Oct 21

TUS

Tucson

STL

St. Louis

$401

Roundtrip

just found

Wed, Oct 14 - Wed, Oct 21

TUS

Tucson

STL

St. Louis

$417

Roundtrip

just found

Tue, Oct 20 - Tue, Oct 27

TUS

Tucson

STL

St. Louis

$635

Roundtrip

just found

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

STL

Lambert-St. Louis Intl.

Cheapest

20 min

Flights from $517

What you need to know for your flight from Tucson Intl. to Lambert-St. Louis Intl.

Tucson (TUS) to St. Louis (STL) at a glance

Explore a range of airlines providing services from Tucson (TUS) to St. Louis (STL) on this domestic short-haul journey. Whether you prefer full-service airlines or budget carriers, you can compare options to discover the itinerary that best suits your budget, schedule, and travel plans while you enjoy the iconic attractions and neighborhoods of St. Louis. Get all the essential information for flights from Tucson International Airport (TUS) to Lambert-St. Louis International Airport (STL).

Fastest (typical) flight duration: around 4 hours in-flight, plus roughly 1 hour layover with one stop
Route distance: roughly 1,200 miles (1,930 km)
Flights per week: around 11 departures on average
Typical fares (one-way): economy tickets often range from $125–$430, depending on seasonality and how far ahead you book

Flights from Tucson International Airport (TUS) to Lambert-St. Louis International Airport (STL)

According to recent traveler bookings, the top airlines for flights from Tucson to St. Louis primarily feature one-stop and multi-stop options. Popular layover cities include Dallas-Fort Worth International Airport (DFW) with an approximate 1 hour and 15-minute layover, Denver International Airport (DEN) with about a 1-hour layover, and Sky Harbor International Airport (PHX), also around 1 hour. This variety allows you to tailor your journey by considering factors like price, total travel time, and cabin class to discover the ideal itinerary.

American Airlines: This full-service airline provides one-stop flights, with one-way ticket prices generally falling between $130 and $485. It operates about 53% of flights on this route, featuring an in-flight duration of 4 hours and a total travel time of around 5 hours and 15 minutes, including layover time.
Southwest Airlines: Known for its budget-friendly options, this low-cost carrier offers one-stop service with one-way fares typically ranging from $125 to $420. Southwest accounts for around 21% of departures on this route, with a flying time of 4 hours and a total journey time of approximately 5 hours and 15 minutes, factoring in layovers.
United: This full-service airline provides both one-stop and multi-stop flights, with one-way fares usually between $135 and $400. United makes up about 17% of the departures on this route, with a standard in-flight duration of 4 hours and a total journey time close to 5 hours and 15 minutes.
Delta: As a full-service airline, Delta offers one-stop service, with one-way fares typically ranging from $130 to $340. It represents about 8% of departures on this route, featuring an in-flight time of 4 hours and a total journey time of around 5 hours and 15 minutes, including layovers.
Frontier Airlines: This low-cost carrier offers one-stop flights, with one-way ticket prices generally between $125 and $245. Frontier accounts for roughly 1% of departures on this route, with a flight time of 4 hours and a total travel time of about 5 hours and 15 minutes, including layover.

Travelers have the option to enhance their journey from Tucson to St. Louis with an upgrade. American Airlines provides first-class service on this route.

Best time to fly from Tucson (TUS) to St. Louis (STL)

The most popular months for travelers flying from Tucson to St. Louis are March, April, and October, when peak temperatures in St. Louis reach up to 58.6°F in October. If you prefer quieter travel, consider August, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 77°F. For better deals, October usually offers the lowest average one-way fare around $202. Flight availability peaks in June, with approximately 13 flights per week, making it easier to find convenient departure times. May has the fewest flights, with approximately 9 flights per week.

Cheapest time to fly: October usually offers good deals with average one-way fare around $202, roughly 15% cheaper than the yearly average.
Another budget-friendly time to fly: August typically offers an average one-way fare of around $219.
Most flight options: June has the highest number of flights from Tucson to St. Louis, with approximately 13 flights per week, giving you more flexibility in scheduling your trip.

Month	Temperature	Demand	Weekly Flights	Average one-way Fare
January	31.6°F (-0.2°C)	Average	10	$256
February	34.9°F (1.6°C)	Average	10	$233
March	46.4°F (8.0°C)	Moderately High	11	$276
April	56.1°F (13.4°C)	Moderately High	10	$248
May	66.6°F (19.2°C)	Moderately Low	9	$224
June	76.1°F (24.5°C)	Average	13	$240
July	78.6°F (25.9°C)	Average	10	$250
August	77.0°F (25.0°C)	Moderately Low	10	$219
September	70.9°F (21.6°C)	Moderately Low	11	$258
October	58.6°F (14.8°C)	Moderately High	12	$202
November	46.2°F (7.9°C)	Average	10	$254
December	37.8°F (3.2°C)	Average	11	$224

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from Tucson (TUS) to St. Louis (STL)

Sierra Vista to St. Louis (FHU-STL): Sierra Vista Municipal Airport (FHU) lies approximately 51 miles from Tucson International Airport (TUS), making it a convenient departure point for travelers heading to St. Louis.
Tucson to Springfield (TUS-SPI): Abraham Lincoln Capital Airport (SPI) is located about 85 miles from Lambert-St. Louis International Airport (STL), offering an alternative route for those flying from Tucson.
Mesa to St. Louis (AZA-STL): Phoenix - Mesa Gateway Airport (AZA) is roughly 92 miles distant from Tucson International Airport (TUS), providing another option for flights to St. Louis.

How to find the best prices for flights from Tucson (TUS) to St. Louis (STL)

Getting some of the best deals on flights from Tucson to St. Louis is all about timing and flexibility. Here are some key tips to help you save:

Best times to book and fly: cheaper fares are generally found when booking 2-8 weeks in advance, which aligns with when most travelers make their reservations. Afternoon departures (12pm-6pm) often offer lower prices, although morning flights (5am-12pm) are more popular. Additionally, flying on Monday tends to be cheaper, while Thursday is the most favored travel day.
Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Lambert-St. Louis International Airport from Tucson International Airport

St. Louis welcomes travelers from Tucson with a range of transport options based on price, convenience, and proximity. Here's how to reach St. Louis efficiently:

Hotel transfer: Transfers offer a convenient way to reach your hotel in St. Louis, with private rides that can be arranged in advance.
Car rental: Renting a car from Lambert-St. Louis International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Lambert-St. Louis International Airport on Expedia.
Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
Public transportation: From Lambert-St. Louis International Airport, Lambert Main Terminal Station, a metro station, is conveniently located just 0.1 miles away on foot, providing easy access to public transport options.

Frequently asked questions

How much does a flight from Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) cost?

You can find cheap one-way flights from $199 and cheap return flights from $367 Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) with Expedia. One-way flights usually range from $146 to $769, and return flights typically cost between $344 and $1094. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.

What is the cheapest month to fly from Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?

January is typically the cheapest month to fly from Tucson, AZ (TUS) to St. Louis, MO (STL), with average round-trip fares around $266. This price is about 33% lower than the average throughout the year, as January often sees reduced travel demand after the holiday season. Other budget-friendly months for this route include August and October.*Averages based on flights available on Expedia in the last year.

Which airlines fly direct from Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?

Enter TUS to STL and your travel dates, then apply the 'Nonstop' filter to see only direct flights.

How do I find cheap flights from Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?

To find a cheap flight from Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.

What is the best time to fly from Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?

For flights from Tucson, AZ (TUS) to St. Louis, MO (STL), January and August are the best months to consider. January is particularly affordable, with return flights averaging around $266, while August is popular, providing a good selection of flights.*Prices based on flights available on Expedia in the last year.

What is the earliest flight from Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?

Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from TUS to STL. To compare more early flights, use the "Early Morning" and "Morning" filters in your search.

What are the most popular departure times for flights from Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?

The most popular departure times for flights from Tucson (TUS) to St. Louis (STL) are in the early morning, from 6am to 9am. About 34% of passengers prefer this time window. Many major carriers, including American Airlines, United Airlines, and Southwest Airlines, offer flights during this window. This timing is popular because it allows travelers to start their day early and make the most of their time in St. Louis.

How long does it take to fly from Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?

Flying from TUS to STL with a connection usually takes about 6 hours, traveling roughly 1,242 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.

Can you fly business or first class from Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?

First class is available on flights from TUS to STL. First class cabins are available on:

United Airlines
Delta Air Lines
American Airlines

How do I earn miles on a Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight with Expedia?

It's easy to earn miles on a Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

What airports do you fly into for St. Louis from Tucson Intl. (TUS)?

From Tucson Intl. (TUS), you can fly into Lambert-St. Louis Intl. (STL) to reach St. Louis. Some flights may connect through major hubs like Denver Intl. (DEN), Harry Reid Intl. (LAS), San Diego Intl. (SAN) before reaching St. Louis. Compare routes and airports on Expedia to find the best flight options for your travel plans.

Is it cheaper to buy a plane ticket from Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) at the last minute?

Typically, booking a last minute flight from Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.

Is it cheaper to book a Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight and hotel package?

Securing a Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) St Louis Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.

Can I cancel or change the date of my flight from Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?

If you booked your Tucson, AZ (TUS-Tucson Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport	Tucson Intl.
Destination airport	Lambert-St. Louis Intl.
Airlines serving	Alaska Airlines, American Airlines, Delta, Southwest Airlines, United
Roundtrip price	$367
Distance	1241 mi
Average flight time	6 hours 40 mins

Book with confidence

Tucson to St. Louis Flights

The cheapest times to fly from Tucson to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Tucson to St. Louis are during the month of November. You can find some of the cheapest flights from Tucson to St. Louis with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Tucson to St. Louis

Sunday is one of the best days to book for cheap flights from Tucson to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Tucson to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Tucson to St. Louis in 2026. You can also book with separate airlines for your outbound and return journeys, from $199 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Tucson to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Tucson to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

*Flight schedules are subject to change.

*Available to One Key members.

Explore a world of travel with Expedia

Flights

$199 Cheap Flights from Tucson (TUS) to St. Louis (STL)

Popular airlines from Tucson International Airport (TUS) to St. Louis Lambert Intl. Airport (STL)

Be in the know

Book smarter

Earn twice

Cheap Flights from Tucson to St. Louis (TUS-STL)

Alternative airports near St. Louis

What you need to know for your flight from Tucson Intl. to Lambert-St. Louis Intl.

Tucson (TUS) to St. Louis (STL) at a glance

Flights from Tucson International Airport (TUS) to Lambert-St. Louis International Airport (STL)

Best time to fly from Tucson (TUS) to St. Louis (STL)

Alternative routes from Tucson (TUS) to St. Louis (STL)

How to find the best prices for flights from Tucson (TUS) to St. Louis (STL)

Arriving at Lambert-St. Louis International Airport from Tucson International Airport

Frequently asked questions

Travel information

Book with confidence

Tucson to St. Louis Flights

Explore a world of travel with Expedia