$167 Cheap Flights from Tucson (TUS) to Knoxville (TYS)

View $167 flight on Sun, Dec 7, 2025Opens in a new window

Popular airlines from Tucson International Airport (TUS) to McGhee Tyson Airport (TYS)

Cheap Flights from Tucson to Knoxville (TUS-TYS)

Prices were available within the past 7 days and start at $167 for one-way flights and $256 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Sun, Dec 7 - Thu, Dec 11
TUS
Tucson
TYS
Knoxville
$256 Roundtrip, found 3 days ago
$256
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sun, Dec 7 from Tucson to Knoxville, returning Thu, Dec 11, priced at $256 found 3 days ago
Frontier Airlines
Fri, Nov 21 - Thu, Dec 11
TUS
Tucson
TYS
Knoxville
$276 Roundtrip, found 4 days ago
$276
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Fri, Nov 21 from Tucson to Knoxville, returning Thu, Dec 11, priced at $276 found 4 days ago
Frontier Airlines
Sun, Dec 7 - Sun, Dec 21
TUS
Tucson
TYS
Knoxville
$298 Roundtrip, found 6 days ago
$298
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Sun, Dec 7 from Tucson to Knoxville, returning Sun, Dec 21, priced at $298 found 6 days ago
Frontier Airlines
Fri, Nov 21 - Thu, Dec 4
TUS
Tucson
TYS
Knoxville
$302 Roundtrip, found 4 days ago
$302
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Fri, Nov 21 from Tucson to Knoxville, returning Thu, Dec 4, priced at $302 found 4 days ago
Frontier Airlines
Mon, Nov 24 - Thu, Dec 11
TUS
Tucson
TYS
Knoxville
$306 Roundtrip, found 4 days ago
$306
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Mon, Nov 24 from Tucson to Knoxville, returning Thu, Dec 11, priced at $306 found 4 days ago
American Airlines
Tue, Dec 2 - Thu, Dec 4
TUS
Tucson
TYS
Knoxville
$309 Roundtrip, found 6 days ago
$309
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Dec 2 from Tucson to Knoxville, returning Thu, Dec 4, priced at $309 found 6 days ago
Frontier Airlines
Mon, Dec 29 - Sun, Jan 18
TUS
Tucson
TYS
Knoxville
$312 Roundtrip, found 6 days ago
$312
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Mon, Dec 29 from Tucson to Knoxville, returning Sun, Jan 18, priced at $312 found 6 days ago
Delta
Tue, Dec 2 - Thu, Dec 4
TUS
Tucson
TYS
Knoxville
$339 Roundtrip, found 6 days ago
$339
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Dec 2 from Tucson to Knoxville, returning Thu, Dec 4, priced at $339 found 6 days ago
United
Tue, Dec 9 - Tue, Dec 16
TUS
Tucson
TYS
Knoxville
$389 Roundtrip, found 8 hours ago
$389
Roundtrip
found 8 hours ago
Select United flight, departing Tue, Dec 9 from Tucson to Knoxville, returning Tue, Dec 16, priced at $389 found 8 hours ago
Southwest Airlines
Wed, Apr 15 - Wed, Apr 22
TUS
Tucson
TYS
Knoxville
$399 Roundtrip, found 1 day ago
$399
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, Apr 15 from Tucson to Knoxville, returning Wed, Apr 22, priced at $399 found 1 day ago

Find the cheapest month to fly from Tucson (TUS) to Knoxville (TYS)

April is typically the cheapest month to fly

From $228 - $608 per traveler.

Alternative airports near Knoxville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to McGhee Tyson TYS. Cheapest and Closest option available. Average driving time to city center is 22 minutes. Flights from $557
TYS
McGhee Tyson
CheapestClosest
Average driving time to city center22 min
Flights from $557

Frequently asked questions

How much does a flight from Tucson Intl. Airport (TUS) to McGhee Tyson Airport (TYS) cost?
Snag a cheap one-way flight from $167 or cheap return flight from $256 from Tucson Intl. Airport (TUS) to McGhee Tyson Airport (TYS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Tucson Intl. Airport (TUS) to McGhee Tyson Airport (TYS)?
The cheapest month to fly from TUS to TYS is December, when demand is low. Off-peak months are typically when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Tucson Intl. Airport (TUS) to McGhee Tyson Airport (TYS)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest TUS to TYS flight.
How many flights per day from Tucson Intl. Airport (TUS) to McGhee Tyson Airport (TYS)?
You'll have to hop on a flight with a layover when traveling from Tucson Intl. Airport (TUS) to McGhee Tyson Airport (TYS). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from TUS to TYS?
Usually you'll find the greatest selection of flight options on a Friday. Tuesdays are often the quietest.* However, this can change depending on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tucson Intl. Airport (TUS) to McGhee Tyson Airport (TYS)?
To land at McGhee Tyson Airport (TYS) on schedule, book a flight that takes off from Tucson Intl. Airport (TUS) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Tucson Intl. Airport (TUS) to McGhee Tyson Airport (TYS) last-minute?
Last-minute fares from TUS to TYS are generally more expensive. To secure the lowest rates, start looking for flights early. That said, if you can play around with your travel dates, you may find a cheap fare right before you leave.
Is it cheaper to book a TUS to TYS flight and hotel package?
Securing a TUS to TYS flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Pick from our wide range of accommodations and then add car rentals, flights and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Tucson Intl. Airport (TUS) to McGhee Tyson Airport (TYS)?
Generally, it's possible to cancel or reschedule your TUS to TYS flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Tucson Intl.
Destination airport
McGhee Tyson
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$256
Distance
1559 mi

Book with confidence

Tucson to Knoxville Flights

The cheapest times to fly from Tucson to Knoxville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Tucson to Knoxville are during the month of December. You can find some of the cheapest flights from Tucson to Knoxville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Tucson to Knoxville

Sunday is one of the best days to book for cheap flights from Tucson to Knoxville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Tucson to Knoxville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Tucson to Knoxville in 2025. You can also book with separate airlines for your outbound and return journeys, from $167 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Tucson to Knoxville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Tucson to Knoxville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Tucson to Knoxville Flights

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*Available to One Key members.