$294 Cheap Flights from Knoxville (TYS) to Mazatlan (MZT)

View $294 flight on Tue, Dec 30, 2025Opens in a new window

Popular airlines from McGhee Tyson Airport (TYS) to General Rafael Buelna Intl. Airport (MZT)

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Cheap Flights from Knoxville to Mazatlan (TYS-MZT)

Prices were available within the past 7 days and start at $294 for one-way flights and $582 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Oct 8 - Thu, Oct 16
TYS
Knoxville
MZT
Mazatlán
$582 Roundtrip, found 4 hours ago
$582
Roundtrip
found 4 hours ago
Select Delta flight, departing Wed, Oct 8 from Knoxville to Mazatlán, returning Thu, Oct 16, priced at $582 found 4 hours ago
Delta
Wed, Oct 8 - Tue, Oct 14
TYS
Knoxville
MZT
Mazatlán
$582 Roundtrip, found 4 hours ago
$582
Roundtrip
found 4 hours ago
Select Delta flight, departing Wed, Oct 8 from Knoxville to Mazatlán, returning Tue, Oct 14, priced at $582 found 4 hours ago
American Airlines
Tue, Dec 30 - Tue, Jan 6
TYS
Knoxville
MZT
Mazatlán
$587 Roundtrip, found 1 day ago
$587
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Dec 30 from Knoxville to Mazatlán, returning Tue, Jan 6, priced at $587 found 1 day ago
American Airlines
Sat, Feb 14 - Fri, Feb 20
TYS
Knoxville
MZT
Mazatlán
$594 Roundtrip, found 18 hours ago
$594
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Sat, Feb 14 from Knoxville to Mazatlán, returning Fri, Feb 20, priced at $594 found 18 hours ago
American Airlines
Tue, Dec 30 - Tue, Jan 6
TYS
Knoxville
MZT
Mazatlán
$596 Roundtrip, found 1 day ago
$596
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Dec 30 from Knoxville to Mazatlán, returning Tue, Jan 6, priced at $596 found 1 day ago
Delta
Mon, Jan 19 - Thu, Jan 22
TYS
Knoxville
MZT
Mazatlán
$597 Roundtrip, found 9 hours ago
$597
Roundtrip
found 9 hours ago
Select Delta flight, departing Mon, Jan 19 from Knoxville to Mazatlán, returning Thu, Jan 22, priced at $597 found 9 hours ago
American Airlines
Sat, Feb 14 - Fri, Feb 20
TYS
Knoxville
MZT
Mazatlán
$604 Roundtrip, found 18 hours ago
$604
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Sat, Feb 14 from Knoxville to Mazatlán, returning Fri, Feb 20, priced at $604 found 18 hours ago
American Airlines
Sat, Feb 14 - Fri, Feb 20
TYS
Knoxville
MZT
Mazatlán
$605 Roundtrip, found 18 hours ago
$605
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Sat, Feb 14 from Knoxville to Mazatlán, returning Fri, Feb 20, priced at $605 found 18 hours ago
Aeromexico
Sat, Jan 17 - Thu, Jan 22
TYS
Knoxville
MZT
Mazatlán
$612 Roundtrip, found 9 hours ago
$612
Roundtrip
found 9 hours ago
Select Aeromexico flight, departing Sat, Jan 17 from Knoxville to Mazatlán, returning Thu, Jan 22, priced at $612 found 9 hours ago
United
Fri, Jan 16 - Sat, Jan 24
TYS
Knoxville
MZT
Mazatlán
$727 Roundtrip, found 9 hours ago
$727
Roundtrip
found 9 hours ago
Select United flight, departing Fri, Jan 16 from Knoxville to Mazatlán, returning Sat, Jan 24, priced at $727 found 9 hours ago
Flights from Knoxville (TYS) to Mazatlan (MZT)
Origin airport
McGhee Tyson
Destination airport
General Rafael Buelna Intl.
Airlines serving
Aeromexico, American Airlines, Delta, United
Roundtrip price
$582
Distance
1593 mi

Knoxville to Mazatlan Flights

The cheapest times to fly from Knoxville to Mazatlan

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Mazatlan are during the month of October. You can find some of the cheapest flights from Knoxville to Mazatlan with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Knoxville to Mazatlan

Sunday is one of the best days to book for cheap flights from Knoxville to Mazatlan: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Knoxville to Mazatlan

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Mazatlan in 2025. You can also book with separate airlines for your outbound and return journeys, from $294 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Mazatlan flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Mazatlan airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from McGhee Tyson Airport (TYS) to General Rafael Buelna Intl. Airport (MZT) cost?
Secure a cheap one-way flight from $294 or cheap return flight from $582 from McGhee Tyson Airport (TYS) to General Rafael Buelna Intl. Airport (MZT) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from McGhee Tyson Airport (TYS) to General Rafael Buelna Intl. Airport (MZT)?
Planning your trip for October may help you find better deals, as it's the cheapest month for flights between TYS and MZT. You'll typically find the lowest prices during the off-season.
What is the cheapest airline that flies from McGhee Tyson Airport (TYS) to General Rafael Buelna Intl. Airport (MZT)?
To find the cheapest airline that'll fly you from TYS to MZT, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from McGhee Tyson Airport (TYS) to General Rafael Buelna Intl. Airport (MZT)?
There aren't any daily direct flights available from McGhee Tyson Airport (TYS) to General Rafael Buelna Intl. Airport (MZT). But you can choose flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be cruising above the clouds before you know it.
What day of the week has the most flights from TYS to MZT?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from McGhee Tyson Airport (TYS) to General Rafael Buelna Intl. Airport (MZT)?
To land at General Rafael Buelna Intl. Airport (MZT) on time, select a flight that leaves McGhee Tyson Airport (TYS) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from McGhee Tyson Airport (TYS) to General Rafael Buelna Intl. Airport (MZT) last-minute?
Last-minute fares from TYS to MZT are generally more expensive. For the best rates, start searching for flights well in advance. That being said, if you're flexible with your travel plans, you may score a cheap ticket right before your trip.
Is it cheaper to book a TYS to MZT flight and hotel package?
You'll typically save money by securing a TYS to MZT flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. After choosing your preferred flights and accommodations, consider adding extras like car rentals, activities and tours.
Can I cancel or change the date of my flight from McGhee Tyson Airport (TYS) to General Rafael Buelna Intl. Airport (MZT)?
Generally, it's possible to cancel or reschedule your TYS to MZT flight. However, if it's been more than 24 hours since booking, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find further details on our Customer Service portal.

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*Available to One Key members.