$522 Cheap Flights from Quito (UIO) to Panama City (ECP)

View $522 flight on Mon, Oct 13, 2025Opens in a new window

Popular airlines from Mariscal Sucre Intl. Airport (UIO) to Northwest Florida Beaches Intl. Airport (ECP)

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Cheap Flights from Quito to Panama City (UIO-ECP)

Prices were available within the past 7 days and start at $522 for one-way flights and $898 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Fri, Mar 6 - Fri, Mar 13
UIO
Quito
ECP
Panama City
$898 Roundtrip, found 2 days ago
$898
Roundtrip
found 2 days ago
Select United flight, departing Fri, Mar 6 from Quito to Panama City, returning Fri, Mar 13, priced at $898 found 2 days ago
United
Fri, Mar 6 - Fri, Mar 13
UIO
Quito
ECP
Panama City
$908 Roundtrip, found 2 days ago
$908
Roundtrip
found 2 days ago
Select United flight, departing Fri, Mar 6 from Quito to Panama City, returning Fri, Mar 13, priced at $908 found 2 days ago
United
Fri, Mar 6 - Fri, Mar 13
UIO
Quito
ECP
Panama City
$936 Roundtrip, found 2 days ago
$936
Roundtrip
found 2 days ago
Select United flight, departing Fri, Mar 6 from Quito to Panama City, returning Fri, Mar 13, priced at $936 found 2 days ago
American Airlines
Fri, Mar 6 - Fri, Mar 13
UIO
Quito
ECP
Panama City
$938 Roundtrip, found 2 days ago
$938
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Mar 6 from Quito to Panama City, returning Fri, Mar 13, priced at $938 found 2 days ago
LATAM Airlines Group
Fri, Mar 6 - Fri, Mar 13
UIO
Quito
ECP
Panama City
$946 Roundtrip, found 2 days ago
$946
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Fri, Mar 6 from Quito to Panama City, returning Fri, Mar 13, priced at $946 found 2 days ago
American Airlines
Fri, Mar 6 - Fri, Mar 13
UIO
Quito
ECP
Panama City
$947 Roundtrip, found 2 days ago
$947
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Mar 6 from Quito to Panama City, returning Fri, Mar 13, priced at $947 found 2 days ago
LATAM Airlines Group
Fri, Mar 6 - Fri, Mar 13
UIO
Quito
ECP
Panama City
$954 Roundtrip, found 2 days ago
$954
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Fri, Mar 6 from Quito to Panama City, returning Fri, Mar 13, priced at $954 found 2 days ago
LATAM Airlines Group
Fri, Mar 6 - Fri, Mar 13
UIO
Quito
ECP
Panama City
$960 Roundtrip, found 2 days ago
$960
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Fri, Mar 6 from Quito to Panama City, returning Fri, Mar 13, priced at $960 found 2 days ago
avianca
Fri, Mar 6 - Fri, Mar 13
UIO
Quito
ECP
Panama City
$1,025 Roundtrip, found 2 days ago
$1,025
Roundtrip
found 2 days ago
Select avianca flight, departing Fri, Mar 6 from Quito to Panama City, returning Fri, Mar 13, priced at $1,025 found 2 days ago
Delta
Fri, Mar 6 - Fri, Mar 13
UIO
Quito
ECP
Panama City
$1,054 Roundtrip, found 2 days ago
$1,054
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Mar 6 from Quito to Panama City, returning Fri, Mar 13, priced at $1,054 found 2 days ago
Flights from Quito (UIO) to Panama City (ECP)
Origin airport
Mariscal Sucre Intl.
Destination airport
Northwest Florida Beaches Intl.
Roundtrip price
$897
Distance
2161 mi

Quito to Panama City Flights

The cheapest times to fly from Quito to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Quito to Panama City are during the month of March. You can find some of the cheapest flights from Quito to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Quito to Panama City

Sunday is one of the best days to book for cheap flights from Quito to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Quito to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Quito to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $522 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Quito to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Quito to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Mariscal Sucre Intl. Airport (UIO) to Northwest Florida Beaches Intl. Airport (ECP) cost?
Grab a cheap one-way flight from $522 or cheap return flight from $898 from Mariscal Sucre Intl. Airport (UIO) to Northwest Florida Beaches Intl. Airport (ECP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Mariscal Sucre Intl. Airport (UIO) to Northwest Florida Beaches Intl. Airport (ECP)?
Planning your trip for March is a good way to save, as it's the cheapest month for flights between UIO and ECP. You'll typically find the lowest prices during the off-season.
What is the cheapest airline that flies from Mariscal Sucre Intl. Airport (UIO) to Northwest Florida Beaches Intl. Airport (ECP)?
To find the cheapest airline that'll fly you from UIO to ECP, use Expedia's filter tool. Customize your search based on what matters most to you, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Mariscal Sucre Intl. Airport (UIO) to Northwest Florida Beaches Intl. Airport (ECP)?
Nonstop flights from Mariscal Sucre Intl. Airport (UIO) to Northwest Florida Beaches Intl. Airport (ECP) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from UIO to ECP?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Mariscal Sucre Intl. Airport (UIO) to Northwest Florida Beaches Intl. Airport (ECP)?
Book a flight from Mariscal Sucre Intl. Airport (UIO) to Northwest Florida Beaches Intl. Airport (ECP) that leaves before 3 PM to reduce the risk of cancellations. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Mariscal Sucre Intl. Airport (UIO) to Northwest Florida Beaches Intl. Airport (ECP) last-minute?
Holding off until just before your departure to book your flight from UIO to ECP generally means paying more. Although you may find some last-minute discounts, they aren't always guaranteed. Be flexible with your itinerary to maximize your chances of scoring a bargain.
Is it cheaper to book an UIO to ECP flight and hotel package?
Compared with arranging hotels and flights separately, booking an UIO to ECP flight and hotel package with Expedia could result in significant savings. Better still, having everything in one place will take the stress out of planning your trip. Just secure your flights and choose from our extensive range of hotels, then customize your trip with other add-ons like activities and car rentals.
Can I cancel or change the date of my flight from Mariscal Sucre Intl. Airport (UIO) to Northwest Florida Beaches Intl. Airport (ECP)?
In most cases, you can modify or cancel your UIO to ECP flight. However, there may be additional fees, especially if you booked over 24 hours ago. Check your itinerary for the airline's fees and rules on flight changes, or if you need further information, go to our Customer Service portal.

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*Available to One Key members.