Find 4 Star Hotels in San Francisco, CA from $122

Indulge in a finer side of San Francisco during your vacation.

• Browse a variety of accommodations with all the glitz and glamour you desire
• Use the mobile booking options and reserve a room whenever is convenient for you
• Book the best rates to spend more on pampering yourself and less on reservations

You’ve worked hard to save up for your trip to San Francisco, so now it’s time to pamper yourself and take a walk on the luxurious side.

When you book your stay at one of the 4-star hotels in San Francisco, you’re in for a real treat. During your jaunt in town, marvel at cultural wonders like the de Young Museum, attend a performance at the San Francisco Symphony, and yield to a little chocolate therapy at Ghirardelli Square. After you return from an exciting day of sightseeing, dine at your hotel’s decadent restaurant, get pumped up at the fitness center, and experience the royal treatment from the friendly concierge staff. No matter what your itinerary includes, there is something in the City by the Bay to entice every luxury traveler.

Even though you’re indulging in Northern California, it doesn’t mean your wallet has to suffer. Relax and enjoy all the city has to offer when you book your stay at one of the four-star hotels in San Francisco right here on Expedia. Whether you want to surprise your honey with a romantic hotel or spoil yourself to a boutique accommodation, we’ll lead you to the luxury. Find all the best deals on San Francisco 4-star hotels, so you can get back to planning your day in Chinatown and lounging in Dolores Park.