Does Big Pine Key have any 4-star all-inclusive resorts?

Use our "All inclusive" filter to search for your next getaway in Big Pine Key where everything is taken care of, from your room to your meals, activities and entertainment. We can also help you find standard 4-star stays in and around this popular destination.

Are there any 4-star casino hotels in Big Pine Key?

To find your perfect getaway in Big Pine Key, use our handy filter to narrow down your search. Boasting resort-style amenities and a superb level of service, staying in a 4-star casino hotel is a sure bet for a good time.

The Best 4 Star Hotels in Big Pine Key, FL from $199

A calm river with boats, lush greenery, and a clear blue sky.

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Our top choices for Big Pine Key 4-star hotels

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Marathon

Frank

$177 nightly

Aug 9 - Aug 10

Total with taxes and fees

Tranquility Bay Beachfront Hotel and Resort

Marathon

Michael J

$237 nightly

Aug 16 - Aug 17

Total with taxes and fees

Grassy Flats Resort & Beach Club

Marathon

Katherine

$227 nightly

Jul 23 - Jul 24

Total with taxes and fees

The Reef at Marathon, Florida Keys

Marathon

Jennifer

Marlin Bay Resort & Marina

Marathon

Chardell

Luxury Villa, 3 Bedrooms, Balcony, Overwater | Terrace/patio

Waterfront Luxury Villa

Marathon Shores

Indigo Reef Marina Homes Close to Boat Slip by Pack and Relax

Marathon Shores

Indigo Reef Marina Homes by Pack and Relax

Marathon

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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Big Pine Key.

Isla Bella Beach Resort & Spa

1 Knights Key Boulevard Marathon FL

$285 nightly

$321 total

Aug 18 - Aug 19

Total with taxes and fees

9.2/10 Wonderful! (1,200 reviews)

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Big Pine Key

Snorkel crystal-clear waters teeming with colorful fish, then spot adorable Key deer at the National Key Deer Refuge. Unwind on pristine beaches like Calusa or Sandspur, where soft sand meets turquoise waves.

See all hotels in Big Pine Key

A beach with clear turquoise water, a red umbrella, and a bridge in the background.

Top Big Pine Key Hotel Reviews

Tranquility Bay Beachfront Hotel and Resort

10/10 Excellent

"Super clean room ,beitiful garden, and soo quiet, relax"

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

10/10 Excellent

"It was amazing stay for a family of 5! It was quiet and the pool experience by the lighthouse was truly magical. We look forward to a s’mores experience the next time we visit at outside campfire pits!"

Find out more about Big Pine Key

Big Pine Key Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Big Pine Key, Florida are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Big Pine Key 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Big Pine Key. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Big Pine Key, Florida, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Big Pine Key hotels offer everything your heart desires.

Frequently asked questions

What are the best 4-star hotels in Big Pine Key?

Make unforgettable vacation memories in Big Pine Key at Little Palm Island Resort & Spa - A Noble House Resort. Highly recommended by Expedia travelers, this 4-star hotel offers lots of amenities for a comfortable and relaxing stay.

How much does it cost to stay in a 4-star hotel in Big Pine Key?

To book a 4-star hotel in Big Pine Key that fits your budget, take advantage of Expedia's filters. Check out what's available during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the cheapest property first.

Search for the lowest price from $321

What's the difference between 5-star and 4-star hotels in Big Pine Key?

If you decide to vacation at a 4-star hotel in Big Pine Key, you'll usually find plenty of amenities to keep you relaxed, such as a pool, restaurant and gym. You can enjoy excellent service and upscale accommodations. Pick a 5-star hotel and you'll get a few extra perks — think on-site spas, concierge assistance and opulent turndown services. You're likely to get additional amenities and first-class services at a 5-star stay, but both are great options for luxury travelers.

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Our top choices for Big Pine Key 4-star hotels

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton