Find 5 Star Hotels in Big Pine Key, FL from $203
Upfront pricingOur total price for your stay includes taxes and fees
Treat yourselfSave 10% or more on over 100,000 hotels worldwide with Member PricesLearn about One Key
Be pickySearch almost a million properties worldwide
Check availability on Big Pine Key 5 Star Hotels
Our top choices for Big Pine Key 5-star hotels
2. Sea Glass Cove
Sea Glass Cove
Explore similar 4-star hotels
Tranquility Bay Beachfront Hotel and Resort
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
Grassy Flats Resort & Beach Club
Learn more about Big Pine Key
Snorkel crystal-clear waters teeming with colorful fish, then spot adorable Key deer at the National Key Deer Refuge. Unwind on pristine beaches like Calusa or Sandspur, where soft sand meets turquoise waves.
See all hotels in Big Pine Key
Top Big Pine Key Hotel Reviews
Find out more about Big Pine Key
Pamper your every desire on your upcoming sabbatical. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Big Pine Key so popular in the last year. There's no reason to delay a getaway to Big Pine Key any longer. Furthermore, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. Book one of Expedia's luxurious 5-star hotels in Big Pine Key and get ready to enjoy the getaway of a lifetime. Don't wait any longer!
Get a Great Deal on 5-Star Hotels in Big Pine Key
Don't be afraid to request the best service from your hotel, along with the best conditions. Exceptional service, delicious meals, and attentive guest service are all ready for you. You're sure to find exactly the accommodation you need. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What creature comforts do you want in your lodging? 24-hour room service, so you can order that chocolate soufflé© in the wee hours of the morning? A reflexology treatment that will leave you feeling refreshed and alive? Butler services? No matter what you want on a perfect getaway, you're bound to find it here. Want to see for yourself? Plenty of visitors recommend this location.
But you aren't going to spend your entire vacation in your room, of course. We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Big Pine Key are waiting for you to relax after a busy day.
Make Your Escape
The results are in, and Big Pine Key 5-star hotels are the place to be when you book your next vacation. These beautiful hotels are highly rated by the guests who stay in them, and you're about to join their ranks. Expedia can help you land a great deal on accommodation. Don't put off your dream vacation any longer. Choose one of Expedia's Big Pine Key 5-star hotels today and relax in the lap of luxury tomorrow.
Frequently asked questions
How much does it cost to stay in a 5-star hotel in Big Pine Key?
- Search for the lowest price per night from $203
What makes a hotel 5 stars in Big Pine Key?
Are there any 5-star all-inclusive resorts in Big Pine Key?
Explore a world of travel with Expedia
- Noble House Hotels in Big Coppitt Key
- Budget in Big Pine Key
- 5 Star Hotels in Marathon
- Pet Friendly in Big Pine Key
- Romantic in Big Pine Key
- Hyatt Hotels in Key West Historic District
- Hotels in No Name Key
- Spa in Big Pine Key
- Hotels in Key West
- Wyndham Hotels in Marathon
- Independent Hotels in Little Torch Key
- All-Inclusive in Big Pine Key
- Pool in Big Pine Key
- Beach in Big Pine Key
- 4 Star Hotels in Big Pine Key
- Family Friendly in Big Pine Key
- Remington Hotels in Sugarloaf Key
- Luxury in Little Torch Key
- Hotels in Big Pine Key
- 5 Star Hotels in Cudjoe Key
- 4 Star Hotels in Ramrod Key
- 3 Star Hotels in Big Pine Key
- Hotels near Calusa Beach
- 5 Star Hotels in Whispering Pines
- 5 Star Hotels in Bahia Honda Key
- Adults Only in Big Pine Key
- Motels in Big Pine Key
- Hotels in Summerland Key
- Resorts in Big Pine Key
- 3 Star Hotels in Summerland Key
- 5 Star Hotels in Ramrod Key
- 2 Star Hotels in Big Pine Key
- 4 Star Hotels in Bahia Honda Key
- Hotels in Conch Key
- 5 Star Hotels in Summerland Key
- 5 Star Hotels in Little Torch Key
- Hilton Hotels in Big Pine Key
- Marriott Hotels & Resorts Hotels in Marathon
- Hotels in Key Colony Beach
- Fishing in Big Pine Key
- Bluegreen Resorts Hotels in Marathon
- 5 Star Hotels in No Name Key
- Kimpton Hotels in Lower Florida Keys
- Key West Historic District Hotels
- Benchmark Hotels in Grassy Key
- Equity Lifestyle Hotels in Ramrod Key
- Hersha Hospitality Hotels in Key West
- Wedding in Big Pine Key
- Hotels in Long Key
- Highgate Independent Hotels in Lower Florida Keys
- Ocean View in Big Pine Key
- Hotels in Marathon
- 2 Star Hotels in Melody Key
- LGBT Friendly in Big Pine Key
- Hotels in Cow Key
- Best Western Hotels in Marathon
- 2 Star Hotels in Bahia Honda Key
- Flights from Miami (MIA) to Marathon (MTH)
- Flights to Little Torch Key
- Flights to Bahia Honda Key
- Flights from Fort Lauderdale (FLL) to Marathon (MTH)
- JetBlue Airways Boston (BOS) to Key West (EYW) flights
- Flights to Summerland Key
- Flights to Big Pine Key
- Flights to Marathon
- Delta Air Lines Atlanta (ATL) to Key West (EYW) flights
- Flights to Cudjoe Key