A beach with palm trees, people relaxing on chairs, and colorful kayaks.

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Check availability on Florida Keys 4 Star Hotels

Tonight
Aug 29 - Aug 30
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Aug 30 - Aug 31
Next weekend
Sep 4 - Sep 6
In two weeks
Sep 11 - Sep 13

Our top choices for Florida Keys 4-star hotels

A pool area with lounge chairs and umbrellas, surrounded by palm trees.
A spacious lobby with high ceilings, large windows, and a central coffee table surrounded by sofas and chairs.
An aerial view of a coastal resort with multiple white buildings, a clear turquoise sea, and lush greenery.
A pathway leading to a pool area with palm trees and a sunset view.

1. Hawks Cay Resort

Hawks Cay Resort
Marathon
United States
Craig
$252 nightly
$282 total
Sep 21 - Sep 22
Total with taxes and fees
Hawks Cay Resort
A hammock on a sandy beach with a view of the sea and a tree overhead.
A table with a glass pitcher, a glass with a slice of lime, and a plate with raspberries and a sprig of rosemary.
A spacious dining area with high ceilings, wicker furniture, and large windows.
A spacious interior with a high ceiling, large windows, and a central chandelier.

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
United States
Vianney
$286 nightly
$322 total
Sep 28 - Sep 29
Total with taxes and fees
Baker's Cay Resort Key Largo, Curio Collection by Hilton
A wooden deck with two lounge chairs, a table with two glasses of champagne and red roses, and a view of the beach and ocean.
A beach with palm trees, a dock, and lounge chairs.
A hotel room with a bed, a sofa, a coffee table, a desk with a lamp, and a view of the ocean.
An aerial view of a resort with a swimming pool, palm trees, and a dock.

3. Amara Cay Resort

Amara Cay Resort
Matecumbe
United States
David A
$206 nightly
$231 total
Sep 3 - Sep 4
Total with taxes and fees
Amara Cay Resort
A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
A beach with thatched umbrellas, palm trees, and blue lounge chairs.
A poolside area with blue chairs and a thatched-roof structure.
A spacious bar area with high ceilings and large windows, offering views of the ocean.

4. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
United States
Matt
$259 nightly
$286 total
Aug 30 - Aug 31
Total with taxes and fees
Reefhouse Resort & Marina
An aerial view of a resort with two swimming pools surrounded by palm trees and sun loungers.
A paved pathway leading to a beach with palm trees and a view of the ocean.
A bar area with a wooden counter, bar stools, and potted plants.
A beachside patio with wooden furniture, a thatched roof, and a view of the ocean.

5. Islander Resort

Islander Resort
Matecumbe
United States
Sonia
$287 nightly
$323 total
Sep 22 - Sep 23
Total with taxes and fees
Islander Resort
An aerial view of a resort with a large pool, palm trees, and a beach.
A restaurant with wooden tables and chairs, a bar area, and a view of the sea.
A beach with clear water, a wooden pier, and lounge chairs under a tree.
A pool area with lounge chairs and umbrellas, a clear sky, and palm trees.

6. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
United States
Rachel
$296 nightly
$333 total
Sep 24 - Sep 25
Total with taxes and fees
Playa Largo Resort & Spa, Autograph Collection
A balcony with wicker chairs, a small table with drinks, and a view of the beach and ocean.
A resort with a pool, beach, and ocean view.
An outdoor dining area with round tables and chairs, a thatched roof, and a view of the sea.
A coastal resort with a beach, a swimming pool, and multiple buildings.

7. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
United States
Dareen
$240 nightly
$270 total
Sep 7 - Sep 8
Total with taxes and fees
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
A swimming pool surrounded by palm trees and lounge chairs.
A beach scene with a wooden deck, palm trees, and a gazebo-like structure.
A wooden deck with blue chairs overlooking a beach with palm trees and the ocean.
An aerial view of a resort with a central swimming pool, surrounded by lush greenery and palm trees, with a view of the ocean.

8. Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
Marathon
United Kingdom
Stuart
$244 nightly
$275 total
Sep 21 - Sep 22
Total with taxes and fees
Tranquility Bay Beachfront Hotel and Resort
A marina with boats docked, a lighthouse, and a resort with outdoor seating.
An outdoor dining area with tables and chairs, a pool, and a view of the sea and boats.
A room with two sofas, a round coffee table, and a small side table with a vase.
A bar area with a long counter, multiple bar stools, and a view of the marina with boats and palm trees.

9. Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
Marathon
Canada
Patricia
$180 nightly
$203 total
Sep 7 - Sep 8
Total with taxes and fees
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
A row of beachside cottages with colorful exteriors, each with a beach chair and umbrella.
A row of colorful beach huts with palm trees in the background.
A beach resort with palm trees, a thatched hut, and a purple building with a window.
A resort with a pool surrounded by palm trees and a view of the ocean.

10. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
United States
Brianne
$214 nightly
$241 total
Aug 31 - Sep 1
Total with taxes and fees
La Siesta Resort & Villas
A resort pool with palm trees and lounge chairs, surrounded by a beachfront.
A modern kitchen with white cabinetry, a stainless steel oven, and a large island with a bowl of fruit.
An aerial view of a resort island with a large building, a swimming pool, and a boat docked nearby.
A resort with a large pool surrounded by lounge chairs, a beach area, and a building with multiple floors.

11. Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
Marathon
United States
Don
Villas At Hawks Cay Resort
A wooden deck with a pool and chairs overlooking a beach with palm trees.
A beach with a wooden walkway leading to the water, palm trees, and a clear sky.
A hotel room with a sofa, a desk, a chair, a TV, and a balcony with curtains.
A bar area with stools, a counter, and hanging lanterns.

12. Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club
Marathon
United States
Tiffany
$205 nightly
$230 total
Sep 28 - Sep 29
Total with taxes and fees
Grassy Flats Resort & Beach Club
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A beachside patio with a thatched roof, two lounge chairs, and a view of the ocean.
A resort with multiple white buildings, each featuring balconies and surrounded by lush greenery and palm trees.
A pool area with clear blue water, white lounge chairs, and palm trees.

13. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
United States
Christian
$383 nightly
$430 total
Sep 29 - Sep 30
Total with taxes and fees
The Islands of Islamorada
A large hotel with a pool, multiple balconies, and palm trees.
A modern living room with a beige sectional sofa, large windows with wooden blinds, and a view of a marina and beach.
A beachside wedding setup with wicker chairs and a white canopy, palm trees, and a sunset view.
A large, two-story hotel with a swimming pool in front.

14. Marlin Bay Resort & Marina

Marlin Bay Resort & Marina
Marathon
United States
Chardell
Marlin Bay Resort & Marina
A covered outdoor area with a wooden deck, white railings, and a view of the ocean.
A swimming pool with lounge chairs and palm trees.
A spacious dining area with a long table, wicker chairs, and hanging wicker lamps.
A resort with multiple buildings, a large central pool, and a view of the ocean.

15. Waterfront Luxury Villa

Waterfront Luxury Villa
Marathon Shores
Waterfront Luxury Villa
A modern kitchen with white cabinetry, a built-in oven, and a large island with stools.
A modern kitchen with white cabinets, a microwave, and a dishwasher. There are three bar stools and a large window overlooking the ocean.
A modern kitchen with a central island, bar stools, and a ceiling fan.

16. Florida Keys Getaway w/ Stunning Ocean Views

Florida Keys Getaway w/ Stunning Ocean Views
Long Key
Florida Keys Getaway w/ Stunning Ocean Views
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Florida Keys.
Cheeca Lodge & Spa

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82 Islamorada FL
$214 nightly
$241 total
Sep 7 - Sep 8
Total with taxes and fees
9.2/10 Wonderful! (1,408 reviews)
Cheeca Lodge & Spa
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

1 Knights Key Boulevard Marathon FL
$263 nightly
$296 total
Aug 31 - Sep 1
Total with taxes and fees
9.2/10 Wonderful! (1,252 reviews)
Isla Bella Beach Resort & Spa
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colorful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

See all hotels in Florida Keys
A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Top Florida Keys Hotel Reviews

Islander Resort

Islander Resort

10/10 Excellent
"It’s a beautiful property right on the water with very nice pool area and right near everything in Islamorada"
Steven 1-night trip
Posted 15 hours ago
Islander Resort
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

10/10 Excellent
"I’d recommend getting breakfast locally instead of the resort’s breakfast. Very friendly and helpful staff."
Dareen 3-night trip
Posted 6 days ago
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Find out more about Florida Keys

You'll see that you are in fine company with a visit to Florida Keys. Vacationers similar to you have made it one of our top most visited locals the past two years. However, "location, location, location" applies to more than just your vacation destination. When you want to make your next vacation extra special, it's all about where you start each new day.

Properties as Gorgeous as Florida Keys

Florida Keys saw thousands of tourists in 2016, and Expedia's comment section boast comments that highlight how fabulous these properties are. When you book a 4-star hotel you can breathe easy knowing that these properties aim to exceed your needs. You'll never have to search for to sustain your exercise routine, an energizing swim, or nice dinner during your stay, thanks to all that these hotels provide. They aim to make their facilities and grounds pleasing from the instant you step onto the property and with every step across their floors. Florida Keys has dozens of wonderful lodgings that make for the ideal holiday.

Rooms have been fashioned to keep you as comfortable as possible, with amenities like premium bedding, designer bathroom products, and in-room tea or coffee. So, sit back and decompress. Moreover, if you find that you're need of something else, you can trust the staff will do their best to ensure you continue to be pleased during your stay there. These accommodations are so lovely that you'll regret the day you have to return home.

Book a 4-Star Hotel in Florida Keys Today!

A trip to Florida Keys should be one that you'll recollect for years to come, and booking a 4-star hotel can help create memories that are fabulous. Book a 4-star hotel in Florida Keys soon, because several other people are too.

Frequently asked questions

What are the best 4-star hotels in Florida Keys?
If your Florida Keys adventure is in Key Largo, stay at Playa Largo Resort & Spa, Autograph Collection. With lots of amenities such as a firepit and a pillowtop mattress, it earns top marks from many Expedia travelers. Another sought-after option here is Bakers Cay Resort Key Largo, Curio Collection by Hilton. It's also rated 4 stars and features a steam room and a swimming pool.
How much does it cost to stay in a 4-star hotel in Florida Keys?
With Expedia's filter tool, scoring a terrific deal on a 4-star hotel in Florida Keys just got easier. Start by keying in your chosen travel dates and length of your stay. Then list the results by price and pick a property that best matches your style and budget.
  • Search for the lowest price from $241
What's the difference between 5-star and 4-star hotels in Florida Keys?
If you choose to stay at a 4-star hotel in Florida Keys, you'll typically find plenty of amenities to keep you relaxed, such as a restaurant, pool and gym. You can enjoy top-quality service and upmarket surroundings. Opt for a 5-star hotel and you'll have access to a few more perks — think concierge assistance, on-site spas and indulgent turndown services. You're likely to get more amenities and exclusive services at a 5-star getaway, but both are terrific options for luxury guests.

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