A person in a red jacket and black boots standing on a sandy beach, a dog walking beside them, and another person paddling a kayak in calm water.

Find 4 Star Hotels in Salem, SC from $165

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Salem 4 Star Hotels

Tonight
Sep 30 - Oct 1
Tomorrow
Oct 1 - Oct 2
This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

Our top choices for Salem 4-star hotels

A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.
A bar area with a counter, multiple chairs, and a display of bottles and glasses.
A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.
A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.

1. The Abernathy of Clemson

The Abernathy of Clemson
Clemson
United States
Robert
$149 nightly
$165 total
Oct 18 - Oct 19
Total with taxes and fees
The Abernathy of Clemson
A forested area with a fire pit and wooden chairs.
A spacious living room with a large window, a stone fireplace, and a bookshelf.
A spacious living area with a large window, a wooden dining table, and a cozy seating arrangement.
A room with a desk, two chairs, a small table with a vase of flowers, and a view of greenery outside.

2. Trailborn Highlands, Outdoor Collection by Marriott Bonvoy

Trailborn Highlands, Outdoor Collection by Marriott Bonvoy
Highlands
United States
David
$219 nightly
$240 total
Oct 28 - Oct 29
Total with taxes and fees
Trailborn Highlands, Outdoor Collection by Marriott Bonvoy
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.
A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.
An outdoor patio with wicker furniture, a round table, and a fountain.
A spacious living area with a sofa, ottoman, and chairs, a dining area with a table, and a kitchen in the background.

3. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson
United States
Laurrie
$186 nightly
$206 total
Oct 12 - Oct 13
Total with taxes and fees
The Shepherd Hotel Downtown Clemson
A white, two-story house with a front porch, surrounded by trees and shrubs.
A two-story building with a white exterior, a front door, and a balcony.
A dining area with round tables, black chairs, and white tablecloths.
A hallway with a wooden bench, a chair, a cabinet, and a painting on the wall.

4. Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
Pendleton
United States
Christine
$172 nightly
$191 total
Oct 30 - Oct 31
Total with taxes and fees
Liberty Hall Bed and Breakfast
A wooden deck with benches and a table, large windows, and a stone pillar.
A cozy living room with a stone fireplace, a ceiling fan, and a large window.
A two-story house with a stone entryway, surrounded by autumn foliage and a clear sky.
A kitchen with wooden cabinets, a granite countertop, a built-in stove, and a refrigerator.

5. Condo w/ Pool & Beach Access in Bear Lake Reserve!

Condo w/ Pool & Beach Access in Bear Lake Reserve!
Bear Lake Reserve
United States
.
Condo w/ Pool & Beach Access in Bear Lake Reserve!
A wooden interior with a hot tub and a pool.
A cozy balcony with wicker furniture, a green lantern, and a sign that says "EXPLORE".
A modern living room with a blue sofa, a wooden side table with a lamp, a ceiling fan, a fireplace, and a large window with blinds.
A bedroom with a wooden bed, a ceiling fan, a nightstand, and a view through a sliding glass door to an outdoor area.

6. Sapphire Valley Condo w/ Pool & Lake Beach Access!

Sapphire Valley Condo w/ Pool & Lake Beach Access!
Cashiers
Sapphire Valley Condo w/ Pool & Lake Beach Access!
A stone building with a pitched roof and wooden beams, surrounded by a well-maintained lawn and potted plants.
A covered patio with a glass table and chairs, a stone pathway, and a view of a green field and hills.
A spacious kitchen with a central island, wooden cabinets, and a large window providing natural light.
A spacious living room with a stone fireplace, leather sofas, and a dining area with a kitchen in the background.

7. Newly Renovated Sky Valley Condo w/ Mtn Views

Newly Renovated Sky Valley Condo w/ Mtn Views
Dillard
United States
winston
Newly Renovated Sky Valley Condo w/ Mtn Views
A wooden gazebo with a roof, surrounded by trees, overlooking a lake.
A modern kitchen with stainless steel appliances, a granite countertop, and large windows offering a view of the outdoors.
A spacious living area with a high ceiling, wooden beams, a grey sofa, a brown leather chair, and a dining table with a plant.
A marina with boats docked, a lifeguard station, and a dock with lounge chairs.

8. Designer Retreat w/ Pool, Golf + Beach Access!

Designer Retreat w/ Pool, Golf + Beach Access!
Salem
United States
Anonymous traveler
Designer Retreat w/ Pool, Golf + Beach Access!
An indoor swimming pool with clear lanes, a covered roof, and a bench area.
Interior
A two-story yellow house with a front porch, a small garden, and a pathway leading to the entrance.
A two-story yellow house with a front porch, surrounded by greenery and a driveway.

9. Wooded Keowee Key Retreat Near Golf & Trails

Wooded Keowee Key Retreat Near Golf & Trails
Salem
Wooded Keowee Key Retreat Near Golf & Trails
A large indoor swimming pool with a wooden interior, surrounded by large windows offering views of the outdoors.
A building with a blue roof, wooden exterior, and a porch with a wooden railing.
A bedroom with a large bed, two bedside tables, a wooden headboard, and a sliding glass door leading to a balcony.
A cozy living room with a stone fireplace, a red armchair, a wooden coffee table, and a dining area with a table and chairs.

10. Sunny Sapphire Townhome w/ Resort Amenities!

Sunny Sapphire Townhome w/ Resort Amenities!
Sapphire
Sunny Sapphire Townhome w/ Resort Amenities!
A spacious dining area with a wooden table and chairs, a fireplace, and large windows offering a view of the outdoors.
A two-story house with a covered porch and a front yard.
A modern kitchen with white cabinets, a wooden island, stainless steel appliances, and a tiled floor.
A backyard with a fire pit, four Adirondack chairs, a wooden shed, and a small wooden structure with a smiley face.

11. Lake Hartwell Frank Howard Home Clemson

Lake Hartwell Frank Howard Home Clemson
Anderson
Lake Hartwell Frank Howard Home Clemson
A spacious living room with a large window, a grey sofa, a coffee table, and a dining area with chairs.
A spacious dining area with a wooden table and chairs, a chandelier, and large windows offering views of the outdoors.
A living room with a sectional sofa, a coffee table, and a rug. There are two windows with a view of trees.
A modern kitchen with white cabinets, a wooden dining table, and a chandelier.

12. Sapphire Home w/ Grill & Pool Access

Sapphire Home w/ Grill & Pool Access
Sapphire
United States
William
Sapphire Home w/ Grill & Pool Access
A swimming pool with a view of the lake and docked boats.
A modern living room with a large window, a flat-screen TV, a leather sofa, a coffee table, and a bookshelf.
A marina with boats docked, surrounded by greenery and trees.
A spacious living area with a high ceiling, a large window with a view of trees, a kitchen with a bar, and a comfortable seating area with a sofa and ottomans.

13. Keowee Key Condo w/ Lake Access & Community Pools!

Keowee Key Condo w/ Lake Access & Community Pools!
Salem
Keowee Key Condo w/ Lake Access & Community Pools!
Interior
A kitchen with white cabinets, a stainless steel refrigerator, a microwave, and a sink.
A hallway with a wooden bench, a chandelier, a door, and a wall with a sign.
A marina with boats docked, a wooden pier, and a clear sky.

14. Lake Keowee Condo w/ Balcony & Resort Amenities!

Lake Keowee Condo w/ Balcony & Resort Amenities!
Salem
Lake Keowee Condo w/ Balcony & Resort Amenities!
A wooden gazebo with a roof and a table and chairs inside, surrounded by trees and overlooking a lake.
A modern building with a prominent wooden entrance canopy, stone pillars, and a clear sky.
A modern kitchen with a stainless steel sink, pendant lighting, and a view to a living area with a sofa and a staircase.
A spacious hotel lobby with a bar area, seating arrangements, and large windows offering views.

15. Tee Times & Lake Days! Luxe Keowee Key Living

Tee Times & Lake Days! Luxe Keowee Key Living
Salem
Tee Times & Lake Days! Luxe Keowee Key Living
A marina with boats docked, a lifeguard station, and a dock with lounge chairs.
A multi-story hotel with a parking lot and a view of a lake.
A sandy beach with a calm lake surrounded by trees.
A spacious dining area with a wooden table, chairs, and a chandelier. A cozy seating area with a sofa and chairs is visible in the background.

16. Lake Keowee Condo: Resort Pools & Lake Access!

Lake Keowee Condo: Resort Pools & Lake Access!
Salem
Lake Keowee Condo: Resort Pools & Lake Access!
A gazebo with a wooden roof and open sides, surrounded by trees and overlooking a body of water.
A marina with boats docked, surrounded by greenery and trees.
A dining area with a wooden table and chairs, a kitchen with white cabinets, and a staircase with a white railing.
A spacious living room with a fireplace, a television, and a staircase leading to an upper level.

17. Salem Vacation Rental w/ Lake Keowee Access!

Salem Vacation Rental w/ Lake Keowee Access!
Salem
Salem Vacation Rental w/ Lake Keowee Access!
A gazebo with a wooden roof and open sides, surrounded by trees and overlooking a body of water.
An aerial view of a residential area with houses, a golf course, and a lake in the background.
A sandy beach with a calm lake surrounded by trees.
A large indoor swimming pool with clear lanes, a covered roof, and seating areas along the sides.

18. Views, Pools & Marina: Lake Keowee Condo!

Views, Pools & Marina: Lake Keowee Condo!
Salem
Views, Pools & Marina: Lake Keowee Condo!
A lodge with a large swimming pool, a guesthouse, and a view of a lake.
A wooden deck with a round table and chairs, benches, and a view of a forested area.
Interior
A kitchen with wooden cabinets, stainless steel appliances, a granite countertop, and bar stools.

19. Lake & Pool Access at Bear Lake Reserve Condo!

Lake & Pool Access at Bear Lake Reserve Condo!
Bear Lake Reserve
Lake & Pool Access at Bear Lake Reserve Condo!
A spacious living room with a wooden ceiling, large windows, a dining table with chairs, a sofa, and a flat-screen TV.
A marina with boats docked, a wooden pier, and a sign warning against feeding the waterfowl.
A bedroom with a sloped ceiling, a bed with a floral bedspread, a dresser, a television, and a window with a view of trees.
A cozy living room with a sofa, coffee table, and a view of the kitchen.

20. Keowee Keys Home w/ Mountains View & Lake Access!

Keowee Keys Home w/ Mountains View & Lake Access!
Salem
United States
KURT
Keowee Keys Home w/ Mountains View & Lake Access!
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Salem

Nestled along Lake Keowee, this small town offers peaceful fishing spots and scenic hiking trails in Devils Fork State Park. Rent a pontoon boat to explore the lake's hidden coves or visit nearby Oconee State Park for waterfall views.

See all hotels in Salem
A kayak on calm water with a forested shoreline and distant mountains.
Photo by Deidree DeHart

Top Salem Hotel Reviews

The Abernathy of Clemson

The Abernathy of Clemson

8/10 Good
"It was a great place to stay, fantastic location, they could do with upgrading the cafe/bar area, it isn’t in keeping with g with the rest of the hotel from a look and food perspective"
Terry 1-night trip
Posted 3 days ago
The Abernathy of Clemson

Find out more about Salem

Salem Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Salem, South Carolina are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Salem 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Salem. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Salem, South Carolina, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Salem hotels offer everything your heart desires.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Salem?
To lock in a 4-star hotel in Salem that matches your budget, take advantage of Expedia's sort and search filters. Take a look at the available options during your chosen dates and use our pricing filter to set your maximum rate. You can also sort your results by the most affordable retreat first.
  • Search for the lowest price from $165
What's the difference between 5-star and 4-star hotels in Salem?
Offering a welcoming traveler experience and upmarket surroundings, 4-star hotels are a wonderful option for your Salem trip. These kinds of accommodations generally feature lots of useful amenities that make it simple to kick back and relax — think complimentary bathrobes, pools and gyms. Or live the high life at a 5-star hotel designed to spoil you with exclusive perks and amenities. Round-the-clock concierge service, oversized bathrooms and world-class dining are typically included at these plush properties.
Does Salem have any 4-star all-inclusive resorts?
Enjoy a stress-free vacation experience where just about everything is included in the one rate by using our "All inclusive" filter. Sticking to your budget is simple when your room, food, activities and entertainment are already taken care of. After something different? Browse the amazing deals on our standard 4-star stays in and around Salem too.

Explore a world of travel with Expedia