Default HTG hotel image

Find 4 Star Hotels in Santa Fe, TX from $110

Check availability on Santa Fe 4 Star Hotels

Tonight
Sep 23 - Sep 24
Tomorrow
Sep 24 - Sep 25
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Our top choices for Santa Fe 4-star hotels

The exterior of the Moody Gardens Hotel with a large entrance, a signboard, and a well-maintained garden area.
A golf course with a water body, sand bunkers, and a distant building.
A restaurant with round tables, wooden chairs, and a central tree with pink flowers.
A spacious lobby with a reception desk, seating area, and large windows.

1. Moody Gardens Hotel, Spa and Convention Center

Moody Gardens Hotel, Spa and Convention Center
Near West End
United States
Yrene
$127 nightly
$145 total
Sep 28 - Sep 29
Total with taxes and fees
Moody Gardens Hotel, Spa and Convention Center
A swimming pool with lounge chairs and palm trees.
A grand hallway with a checkered floor, ornate chandeliers, and seating areas.
A luxurious lobby with a brown leather sofa, a round table, and a chandelier.
A large, multi-story hotel with a symmetrical facade, a central courtyard with a covered seating area, and palm trees surrounding the property.

2. Grand Galvez Resort, Autograph Collection

Grand Galvez Resort, Autograph Collection
San Jacinto
United States
Caty
$206 nightly
$237 total
Oct 11 - Oct 12
Total with taxes and fees
Grand Galvez Resort, Autograph Collection
A pool area with lounge chairs and palm trees, surrounded by a building with balconies.
An outdoor lounge area with seating, a fire pit, and a bar.
A spacious lobby with a grand chandelier, elegant furniture, and large windows offering views of palm trees and a building.
A spacious lobby with a large window offering a view of palm trees and a body of water. There are several seating areas with modern furniture and a glass coffee table.

3. The San Luis Resort, Spa & Conference Center

The San Luis Resort, Spa & Conference Center
Midtown
$220 nightly
$253 total
Sep 30 - Oct 1
Total with taxes and fees
The San Luis Resort, Spa & Conference Center
An indoor dining area with tables and chairs, a central fountain, and a stone wall with a lion sculpture.
A dining area with multiple tables and chairs, a stone fireplace, and a large window.
A lobby with a large window, a stone wall, a circular seating area, and a patterned floor.
A spacious hotel lobby with a large chandelier, a reception desk, and a view of the outdoors through large windows.

4. Doubletree by Hilton Houston Hobby Airport

Doubletree by Hilton Houston Hobby Airport
Southeast Houston
United States
Todd
$94 nightly
$110 total
Oct 1 - Oct 2
Total with taxes and fees
Doubletree by Hilton Houston Hobby Airport
A cozy living room with a large window overlooking the sea, a comfortable seating area, and a dining table with chairs.
A hotel patio with wooden furniture, umbrellas, and a sign reading "Hotel Lucine."
A spacious living area with a sofa set, a coffee table, and a bookshelf.
A spacious room with large windows, a wooden desk, and a potted plant.

5. Hotel Lucine

Hotel Lucine
San Jacinto
United States
Felicia
$157 nightly
$181 total
Oct 4 - Oct 5
Total with taxes and fees
Hotel Lucine
A pool area with lounge chairs, a thatched-roof structure, palm trees, and a sign for 'Longboard Pool Bar'.
A modern restaurant with wooden tables and chairs, large windows with a view, and a decorative wall art piece.
A hotel lobby with a circular ceiling light, seating area, reception desk, and a view into the dining area.
A modern hotel lobby with a reception desk, seating area, and a large circular chandelier.

6. DoubleTree by Hilton Hotel Galveston Beach

DoubleTree by Hilton Hotel Galveston Beach
San Jacinto
United States
Monica
$106 nightly
$122 total
Oct 5 - Oct 6
Total with taxes and fees
DoubleTree by Hilton Hotel Galveston Beach
A grand building with ornate columns and a balcony adorned with lights.
A two-story building with a balcony, flags, and outdoor seating.
A bedroom with a large bed, bedside tables, a chair, and a fireplace.
A room with hardwood flooring, a ceiling fan, a door with a window, a small table with a vase, and a gray armchair.

7. The George Manor

The George Manor
East End
United States
Kerri
$200 nightly
$230 total
Sep 27 - Sep 28
Total with taxes and fees
The George Manor
A two-story house with a front porch, a staircase, and a white picket fence.
A spacious living room with a large arched doorway, a blue armchair, a sofa, a coffee table, and a chandelier.
A well-lit living room with leather chairs, a round coffee table, and a fireplace.
A cozy room with a fireplace, wooden furniture, and large windows.

8. Carr Mansion

Carr Mansion
Midtown
United States
Prisilla
$268 nightly
$309 total
Oct 12 - Oct 13
Total with taxes and fees
Carr Mansion
A living room with two sofas, a coffee table, and a painting of a boat on the wall.
A dining area with a wooden table, black chairs, and a hanging light fixture.
A living room with a grey sofa, a black ottoman, a wooden chair, and a small table with a lamp.
A neatly made bed with a grey quilt, white pillows, and a fluffy white throw.

9. Pleasure Pier Retreat Manor by Ryson Vacation Rentals

Pleasure Pier Retreat Manor by Ryson Vacation Rentals
Kempner Park
United States
Dolores
Pleasure Pier Retreat Manor by Ryson Vacation Rentals
A swimming pool with tiled edges, surrounded by lounge chairs and umbrellas, with a building in the background.
A spacious indoor area with a pool table, ping pong table, and bar stools. There are large windows providing natural light and a television mounted on a wall.
A spacious living room with a large flat-screen TV, a sofa set, a coffee table, and a pool table.
A modern kitchen with a granite countertop, stainless steel appliances, and a bar area with stools.

10. Landing Houston Space Center

Landing Houston Space Center
Nassau Bay
United States
Tonia
Landing Houston Space Center
A modern kitchen with stainless steel appliances, wooden ceiling, and pendant lighting.
A water park with multiple slides and pools.
A spacious living area with a wooden ceiling, a dining table with a unique wooden top, and a kitchen in the background.
An outdoor patio with a stone wall, a fire pit, and a covered seating area.

11. Gulf Siesta Vacation Lofts

Gulf Siesta Vacation Lofts
Midtown
United States
Liana
$117 nightly
$134 total
Sep 28 - Sep 29
Total with taxes and fees
Gulf Siesta Vacation Lofts
A wooden boardwalk leading to a beach with a clear sky and ocean view.
A living room with a sofa, a red chair, a coffee table, and two paintings on the wall.
A wooden boardwalk leading to a beach with a metal gate and palm tree design.
A small building with a sign that reads "Seascape Resort Rental Condominiums."

12. Abundant Relaxation by Ryson Vacation Rentals

Abundant Relaxation by Ryson Vacation Rentals
Near West End
United States
Robert H
Abundant Relaxation by Ryson Vacation Rentals
A modern kitchen with a large island, stainless steel sink, and a dining area with a table and chairs.
A modern living room with a sofa, two armchairs, a coffee table, and a ceiling fan.
A modern kitchen with white cabinetry, a central island, and a dining area with a view of the living room.
A spacious living area with a wooden dining table, a TV mounted on the wall, and a balcony with a view.

13. Ocean-view Balcony: Family Gem on Seawall Blvd!

Ocean-view Balcony: Family Gem on Seawall Blvd!
Near West End
United States
Michael
Ocean-view Balcony: Family Gem on Seawall Blvd!
A spacious indoor area with a pool table, dining tables, and chairs. There are ceiling fans, recessed lighting, and a stone accent wall.
A covered outdoor patio with a table and chairs, a railing, and a view of the landscape.
A spacious kitchen with a large island, wooden dining table, and chairs.
A two-story house with a covered porch, a garage, and a parking lot with marked spaces.

14. Harborwalk Lodge

Harborwalk Lodge
Hitchcock
United States
David
Harborwalk Lodge
A swimming pool area with multiple pools, lounge chairs, and palm trees.
A pool area with palm trees, outdoor seating, and a view of the ocean.
A bedroom with a bed, bedside table, lamp, and a view of the outside through a window.
A modern kitchen with dark wood cabinets, a granite countertop, stainless steel appliances, and a 'Laundry' sign on the wall.

15. Beach Daze by Ryson Vacation Rentals

Beach Daze by Ryson Vacation Rentals
Near West End
United States
Patricia
Beach Daze by Ryson Vacation Rentals
A spacious indoor area with large windows, wicker furniture, and a view of the outdoors.
A spacious lobby with a high ceiling, a central seating area, and large windows allowing natural light.
A conference room with a round table, wicker chairs, and a large window with a city view.
An outdoor pool area with a barbecue and a view of the ocean.

16. Emerald 705 by Ryson Vacation Rentals

Emerald 705 by Ryson Vacation Rentals
Stewart Beach
United States
Cheri
Emerald 705 by Ryson Vacation Rentals
A resort with a swimming pool, palm trees, and a view of the ocean.
A living room with a black entertainment center, leather sofas, a glass coffee table, and a view of the outdoors through a sliding glass door.
A bedroom with a bed, a wooden wardrobe, a ceiling fan, and a door leading to another room.
A kitchen with a stainless steel stove, microwave, and refrigerator, granite countertops, wooden cabinets, and a dining area with a table and chairs.

17. At The Beach by Ryson Vacation Rentals

At The Beach by Ryson Vacation Rentals
Near West End
United States
Rodney
At The Beach by Ryson Vacation Rentals
A modern kitchen with a central island, stainless steel appliances, and a brick backsplash.
A modern kitchen with a dining area, large windows, and a ceiling fan.
A covered porch with a ceiling fan, wicker chairs, and a view of a blue house.
A two-story house with a pool, a covered patio, and a wooden deck.

18. Hidden Paradise

Hidden Paradise
San Jacinto
$1,042 nightly
$1,137 total
Sep 27 - Sep 28
Total with taxes and fees
Hidden Paradise
A swimming pool surrounded by multi-story buildings with balconies, palm trees, and a clear blue sky.
A living room with a sofa, coffee table, and a ceiling fan.
A gym with various exercise equipment, large windows, and a television mounted on the wall.
A bedroom with a bed, nightstand, desk, and a ceiling fan.

19. Oasis at the Dawn by Ryson Vacation Rentals

Oasis at the Dawn by Ryson Vacation Rentals
Near West End
United States
Kimberly
Oasis at the Dawn by Ryson Vacation Rentals
A dining area with a chandelier, a sofa, a dining table with chairs, and a refrigerator.
A balcony with wicker furniture, a patterned rug, and a view of a building and landscape.
A reception area with a counter, three bar stools, a potted plant, a whiteboard, and a wall-mounted decorative item.
A living room with a sofa, a wooden cabinet, a chandelier, and a patterned rug.

20. Harbor East Condominiums 414D by Ryson Vacation Rentals

Harbor East Condominiums 414D by Ryson Vacation Rentals
Fish Village
United States
John
Harbor East Condominiums 414D by Ryson Vacation Rentals
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Fe Hotel Reviews

Moody Gardens Hotel, Spa and Convention Center

Moody Gardens Hotel, Spa and Convention Center

10/10 Excellent
"Our stay at the Moody Gardens Hotel was excellent! It’s such a beautiful hotel, and our room was HUGE! I loved the super-high ceiling!"
Laura 1-night trip
Posted less than an hour ago
Moody Gardens Hotel, Spa and Convention Center
The San Luis Resort, Spa & Conference Center

The San Luis Resort, Spa & Conference Center

10/10 Excellent
"This was a great hotel to stay out prior to our cruise. It was very elegant, clean, and had different activities to do. The pool area was great for our family and every single one of the staff members was very helpful. We could not have asked for better service. We most definitely want to stay here again and try the steakhouse. If you want to splurge and have a great time at Galveston, do not hesitate to book this hotel because you will not regret it."
Jessica 1-night trip
Posted 1 hour ago
The San Luis Resort, Spa & Conference Center
Grand Galvez Resort, Autograph Collection

Grand Galvez Resort, Autograph Collection

10/10 Excellent
"Beautiful hotel! Enjoyed every moment."
Yolanda 2-night trip
Posted 23 hours ago
Grand Galvez Resort, Autograph Collection

Find out more about Santa Fe

Santa Fe Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Santa Fe, Texas are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Santa Fe 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Santa Fe. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Santa Fe, Texas, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Santa Fe hotels offer everything your heart desires.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Santa Fe?
We can help you easily find the perfect 4-star hotel for your getaway in Santa Fe. Use our handy filter tool to fine-tune your search by things like price, conveniences and property star rating and get access to awesome deals in a few clicks.
  • Search for the lowest price from $110
What's the difference between 5-star and 4-star hotels in Santa Fe?
Treat yourself to refined living during your Santa Fe vacation by staying at a 4-star hotel. As well as featuring upscale accommodations, these properties are usually packed with amenities, including large beds, bathrobes and more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and unforgettable one. 24-hour front desk, elegant décor and world-class dining are only the start of the exclusive conveniences and services you'll likely get access to.
Does Santa Fe have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to search for your next escape in Santa Fe where just about everything is taken care of, from your room to your meals, entertainment and activities. We can also help you find standard 4-star stays in and around this sought-after destination.

Explore a world of travel with Expedia