Title: The Best 4 Star Hotels in St Mary, MO  | Expedia.com

[St Mary Travel Guide](https://expedia.com/St-Mary.dx3000445480)[Hotels in St Mary](https://expedia.com/St-Mary-Hotels.d3000445480.Travel-Guide-Hotels)[Vacation Rentals in St Mary](https://expedia.com/St-Mary-Vacation-Rentals.d3000445480.Travel-Guide-VacationRentals)[Flights to St Mary](https://expedia.com/Cheap-Flights-To-St-Mary.d3000445480.Travel-Guide-Flights)[Car Rentals in St Mary](https://expedia.com/Car-Rentals-In-St-Mary.d3000445480.Car-Rental-Guide)[St Mary Vacation Packages](https://expedia.com/St-Mary.d3000445480.Destination-Travel-Guides)

![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg)  
###  
Upfront pricing  
Our total price for your stay includes taxes and fees
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)  
###  
Treat yourself  
Save 10% or more on over 100,000 hotels worldwide with Member Prices  
[Learn about One Key](https://www.expedia.com/welcome-one-key)
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg)  
###  
Be picky  
Search almost a million properties worldwide

## Check availability on St Mary 4 Star Hotels

Tonight

[Mar 19 - Mar 20](https://www.expedia.com/Hotel-Search?regionId=3000445480&startDate=2026-03-19&endDate=2026-03-20&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 20 - Mar 21](https://www.expedia.com/Hotel-Search?regionId=3000445480&startDate=2026-03-20&endDate=2026-03-21&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=3000445480&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=3000445480&startDate=2026-03-27&endDate=2026-03-29&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for St Mary 4-star hotels

![Street view](https://images.trvl-media.com/lodging/40000000/39930000/39926100/39926011/1b66adae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![City view from property](https://images.trvl-media.com/lodging/40000000/39930000/39926100/39926011/4840d660.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, streaming services](https://images.trvl-media.com/lodging/40000000/39930000/39926100/39926011/eeb333c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/40000000/39930000/39926100/39926011/198bc377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Urban Lofts

[](https://www.expedia.com/Perryville-Hotels-Urban-Lofts.h39926011.Hotel-Information)

Perryville

[](https://www.expedia.com/Perryville-Hotels-Urban-Lofts.h39926011.Hotel-Information)

![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg)

Save an average of 15% on thousands of hotels when you're signed in

[Sign in

](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-St-Mary-Hotels.s40-0-d3000445480.Travel-Guide-Filter-Hotels)[

Sign up, it's free

](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-St-Mary-Hotels.s40-0-d3000445480.Travel-Guide-Filter-Hotels)

## Top St Mary Hotel Reviews

## Find out more about St Mary

## St Mary Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in St Mary, Missouri are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the St Mary 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in St Mary. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in St Mary, Missouri, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star St Mary hotels offer everything your heart desires.

## Frequently asked questions

### How much does it cost to stay in a 4-star hotel in St Mary?

> - Search for the lowest price

### What's the difference between 5-star and 4-star hotels in St Mary?

### Does St Mary have any 4-star all-inclusive resorts?

## Explore a world of travel with Expedia

- Lodging
- Flights
- Packages
- Cars
- Vacation Rentals

- [Ozora Hotels ](https://www.expedia.com/Ozora-Hotels.d553248635975852499.Travel-Guide-Hotels)
- [3 Star Hotels in Ste Genevieve ](https://www.expedia.com/3Star-Ste-Genevieve-Hotels.s30-0-d183502.Travel-Guide-Filter-Hotels)
- [5 Star Hotels in Ste Genevieve ](https://www.expedia.com/5Star-Ste-Genevieve-Hotels.s50-0-d183502.Travel-Guide-Filter-Hotels)
- [4 Star Hotels in Ste Genevieve ](https://www.expedia.com/4Star-Ste-Genevieve-Hotels.s40-0-d183502.Travel-Guide-Filter-Hotels)
- [Ste Genevieve Hotels ](https://www.expedia.com/Ste-Genevieve-Hotels.d183502.Travel-Guide-Hotels)
- [B&B in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Bed-And-Breakfast.d183502-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Cabin Rentals in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Cabins.d183502-aaCabins.Travel-Guide-Accommodation)
- [Hotels near Felix Valle House State Historic Site ](https://www.expedia.com/Felix-Valle-House-State-Historic-Site-Hotels.0-l553248621532648573-0.Travel-Guide-Filter-Hotels)
- [Winery Hotels in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Hotels-Winery-Hotel.0-0-d183502-tWineryHotel.Travel-Guide-Filter-Hotels)
- [Hotels near Sainte Genevieve Winery ](https://www.expedia.com/Sainte-Genevieve-Winery-Hotels.0-l553248621532648574-0.Travel-Guide-Filter-Hotels)
- [Romantic Hotels in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Hotels-Romantic-Hotel.0-0-d183502-tRomanticHotel.Travel-Guide-Filter-Hotels)
- [Pet-Friendly Hotels in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Hotels-Pet-Friendly-Hotel.0-0-d183502-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
- [Historic Hotels in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Hotels-Historic-Hotel.0-0-d183502-tHistoricHotel.Travel-Guide-Filter-Hotels)
- [Hotels with a Pool in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Hotels-Hotel-With-Pool.0-0-d183502-tHotelwithPool.Travel-Guide-Filter-Hotels)
- [Motels in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Motels.d183502-aaMotels.Travel-Guide-Accommodation)
- [Farmstay in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Agritourism.d183502-aaAgritourism.Travel-Guide-Accommodation)
- [Hotels with Hot Tubs in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Hotels-Hotels-With-Hot-Tubs.0-0-d183502-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels)
- [Hotels with an Outdoor Pool in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Hotels-Hotels-With-Outdoor-Pool.0-0-d183502-tHotelswithOutdoorPool.Travel-Guide-Filter-Hotels)
- [Cottages in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Cottages.d183502-aaCottages.Travel-Guide-Accommodation)
- [Hilton Hotels in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Hotels-Hilton-Hotels.0-0-d183502--bHiltonHotels.Travel-Guide-Filter-Hotels)
- [Villas in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Villas.d183502-aaVillas.Travel-Guide-Accommodation)
- [Hotels with Restaurants in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Hotels-Hotels-With-Restaurants.0-0-d183502-tHotelswithRestaurants.Travel-Guide-Filter-Hotels)
- [Apartments in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Apartments.d183502-aaApartments.Travel-Guide-Accommodation)
- [Luxury Hotels in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Hotels-Luxury-Hotel.0-0-d183502-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Condo Rentals in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Condos.d183502-aaCondos.Travel-Guide-Accommodation)
- [Family Hotels in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Hotels-Family-Hotel.0-0-d183502-tFamilyHotel.Travel-Guide-Filter-Hotels)
- [Business Hotels in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Hotels-Business-Hotel.0-0-d183502-tBusinessHotel.Travel-Guide-Filter-Hotels)
- [Hotels with Bars in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Hotels-Bar-Hotel.0-0-d183502-tBarHotel.Travel-Guide-Filter-Hotels)
- [Vacation Homes in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Private-Vacation-Homes.d183502-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Hotels with Free Parking in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Hotels-Hotels-With-Free-Parking.0-0-d183502-tHotelswithFreeParking.Travel-Guide-Filter-Hotels)
- [Castles in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Castles.d183502-aaCastles.Travel-Guide-Accommodation)
- [Non-Smoking Hotels in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Hotels-Smoke-Free-Hotels.0-0-d183502-tSmokeFreeHotels.Travel-Guide-Filter-Hotels)
- [Condo Resorts in Ste Genevieve ](https://www.expedia.com/Ste-Genevieve-Condominium-Resort.d183502-aaCondominiumResort.Travel-Guide-Accommodation)
- [Hotels near Cave Vineyard ](https://www.expedia.com/Cave-Vineyard-Hotels.0-l553248621532648478-0.Travel-Guide-Filter-Hotels)
- [Hotels near Missouri's National Veterans Memorial ](https://www.expedia.com/Missouris-National-Veterans-Memorial-Hotels.0-l620724250067501056-0.Travel-Guide-Filter-Hotels)
- [Hotels near National Shrine of Our Lady of the Miraculous Medal ](https://www.expedia.com/National-Shrine-Of-Our-Lady-Of-The-Miraculous-Medal-Hotels.0-l553248621561876731-0.Travel-Guide-Filter-Hotels)
- [Perryville Hotels ](https://www.expedia.com/Perryville-Hotels.d6134448.Travel-Guide-Hotels)
- [Cabin Rentals in Perryville ](https://www.expedia.com/Perryville-Cabins.d6134448-aaCabins.Travel-Guide-Accommodation)
- [Motels in Perryville ](https://www.expedia.com/Perryville-Motels.d6134448-aaMotels.Travel-Guide-Accommodation)
- [Historic Hotels in Perryville ](https://www.expedia.com/Perryville-Hotels-Historic-Hotel.0-0-d6134448-tHistoricHotel.Travel-Guide-Filter-Hotels)
- [Pet-Friendly Hotels in Perryville ](https://www.expedia.com/Perryville-Hotels-Pet-Friendly-Hotel.0-0-d6134448-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
- [Apartments in Perryville ](https://www.expedia.com/Perryville-Apartments.d6134448-aaApartments.Travel-Guide-Accommodation)
- [Hotels with Hot Tubs in Perryville ](https://www.expedia.com/Perryville-Hotels-Hotels-With-Hot-Tubs.0-0-d6134448-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels)
- [Cheap Hotels in Perryville ](https://www.expedia.com/Perryville-Hotels-Cheap-Hotels.0-0-d6134448-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Winery Hotels in Perryville ](https://www.expedia.com/Perryville-Hotels-Winery-Hotel.0-0-d6134448-tWineryHotel.Travel-Guide-Filter-Hotels)
- [Resorts & Hotels with Spas in Perryville ](https://www.expedia.com/Perryville-Hotels-Spa-Hotel.0-0-d6134448-tSpaHotel.Travel-Guide-Filter-Hotels)
- [Hotel Wedding Venues Hotels in Perryville ](https://www.expedia.com/Perryville-Hotels-Wedding-Hotels.0-0-d6134448-tWeddingHotels.Travel-Guide-Filter-Hotels)
- [Hotels with an Indoor Pool in Perryville ](https://www.expedia.com/Perryville-Hotels-Hotels-With-Indoor-Pool.0-0-d6134448-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels)
- [Hotels with an Outdoor Pool in Perryville ](https://www.expedia.com/Perryville-Hotels-Hotels-With-Outdoor-Pool.0-0-d6134448-tHotelswithOutdoorPool.Travel-Guide-Filter-Hotels)
- [Golf Hotels in Perryville ](https://www.expedia.com/Perryville-Hotels-Golf-Hotel.0-0-d6134448-tGolfHotel.Travel-Guide-Filter-Hotels)
- [Hotels with Bars in Perryville ](https://www.expedia.com/Perryville-Hotels-Bar-Hotel.0-0-d6134448-tBarHotel.Travel-Guide-Filter-Hotels)
- [Hotels with a Pool in Perryville ](https://www.expedia.com/Perryville-Hotels-Hotel-With-Pool.0-0-d6134448-tHotelwithPool.Travel-Guide-Filter-Hotels)
- [Non-Smoking Hotels in Perryville ](https://www.expedia.com/Perryville-Hotels-Smoke-Free-Hotels.0-0-d6134448-tSmokeFreeHotels.Travel-Guide-Filter-Hotels)
- [Hotels with Connecting Rooms in Perryville ](https://www.expedia.com/Perryville-Hotels-Hotels-With-Adjoining-Rooms.0-0-d6134448-tHotelswithAdjoiningRooms.Travel-Guide-Filter-Hotels)
- [Hotels with Laundry Facilities in Perryville ](https://www.expedia.com/Perryville-Hotels-Hotels-With-Laundry-Facilities.0-0-d6134448-tHotelswithLaundryFacilities.Travel-Guide-Filter-Hotels)
- [Hotels near Perryville Country Club ](https://www.expedia.com/Perryville-Country-Club-Hotels.0-l553248621564822920-0.Travel-Guide-Filter-Hotels)
- [New Offenburg Hotels ](https://www.expedia.com/New-Offenburg-Hotels.d3000349478.Travel-Guide-Hotels)
- [Cottages in New Offenburg ](https://www.expedia.com/New-Offenburg-Cottages.d3000349478-aaCottages.Travel-Guide-Accommodation)
- [Hotels near Crown Valley Winery ](https://www.expedia.com/Crown-Valley-Winery-Hotels.0-l553248621532648473-0.Travel-Guide-Filter-Hotels)
- [Weingarten Hotels ](https://www.expedia.com/Weingarten-Hotels.d553248635975847364.Travel-Guide-Hotels)
- [Hotels near Weingarten Vineyard ](https://www.expedia.com/Weingarten-Vineyard-Hotels.0-l553248621532648476-0.Travel-Guide-Filter-Hotels)
- [Hotels near Hawn State Park ](https://www.expedia.com/Hawn-State-Park-Hotels.0-l553248621532648475-0.Travel-Guide-Filter-Hotels)
- [3 Star Hotels in Bloomsdale ](https://www.expedia.com/3Star-Bloomsdale-Hotels.s30-0-d3000444549.Travel-Guide-Filter-Hotels)

- [Flights to Ste Genevieve ](https://www.expedia.com/Cheap-Flights-To-Ste-Genevieve.d183502.Travel-Guide-Flights)
- [Flights from Ste Genevieve ](https://www.expedia.com/lp/flights/183502/flights-from-ste-genevieve)
- [Flights to Perryville ](https://www.expedia.com/Cheap-Flights-To-Perryville.d6134448.Travel-Guide-Flights)
- [Flights from Perryville ](https://www.expedia.com/lp/flights/6134448/flights-from-perryville)
- [Flights from New Offenburg ](https://www.expedia.com/lp/flights/3000349478/flights-from-new-offenburg)

- [Visit Ste Genevieve ](https://www.expedia.com/Ste-Genevieve.dx183502)
- [Felix Valle House State Historic Site ](https://www.expedia.com/Felix-Valle-House-State-Historic-Site-Ste-Genevieve.d553248621532648573.Vacation-Attraction)
- [Ste Genevieve Vacations ](https://www.expedia.com/Ste-Genevieve.d183502.Destination-Travel-Guides)
- [Cave Vineyard ](https://www.expedia.com/Cave-Vineyard-Ste-Genevieve.d553248621532648478.Vacation-Attraction)
- [Missouri's National Veterans Memorial ](https://www.expedia.com/Missouris-National-Veterans-Memorial-Perryville.d620724250067501056.Vacation-Attraction)
- [National Shrine of Our Lady of the Miraculous Medal ](https://www.expedia.com/National-Shrine-Of-Our-Lady-Of-The-Miraculous-Medal-Perryville.d553248621561876731.Vacation-Attraction)
- [Visit Perryville ](https://www.expedia.com/Perryville.dx6134448)
- [Perryville Vacations ](https://www.expedia.com/Perryville.d6134448.Destination-Travel-Guides)
- [Perryville Country Club ](https://www.expedia.com/Perryville-Country-Club-Perryville.d553248621564822920.Vacation-Attraction)
- [Visit New Offenburg ](https://www.expedia.com/New-Offenburg.dx3000349478)
- [Crown Valley Winery ](https://www.expedia.com/Crown-Valley-Winery-Ste-Genevieve.d553248621532648473.Vacation-Attraction)
- [Weingarten Vineyard ](https://www.expedia.com/Weingarten-Vineyard-Ste-Genevieve.d553248621532648476.Vacation-Attraction)
- [Hawn State Park ](https://www.expedia.com/Hawn-State-Park-Ste-Genevieve.d553248621532648475.Vacation-Attraction)

- [Discount Car Rentals Rental Cars in Lithium ](https://www.expedia.com/Discount-Car-Rentals-Car-Rentals-In-Lithium.d553248634983113033-c11.Car-Rental-Guide-Suppliers)
- [Car rentals near Lithium ](https://www.expedia.com/Car-Rentals-In-Lithium.d553248634983113033.Car-Rental-Guide)
- [Car rentals near Ozora ](https://www.expedia.com/Car-Rentals-In-Ozora.d553248635975852499.Car-Rental-Guide)
- [Car rentals near Ste Genevieve ](https://www.expedia.com/Car-Rentals-In-Ste-Genevieve.d183502.Car-Rental-Guide)
- [Hertz Rental Cars in Ste Genevieve ](https://www.expedia.com/Hertz-Car-Rentals-In-Ste-Genevieve.d183502-c40.Car-Rental-Guide-Suppliers)
- [Van Car Rentals in Ste Genevieve ](https://www.expedia.com/Van-Car-Rentals-In-Ste-Genevieve.d183502-tVan.Car-Rental-Guide-Class)
- [Budget Rental Cars in Ste Genevieve ](https://www.expedia.com/Budget-Car-Rentals-In-Ste-Genevieve.d183502-c39.Car-Rental-Guide-Suppliers)
- [Enterprise Rental Cars in Ste Genevieve ](https://www.expedia.com/Enterprise-Car-Rentals-In-Ste-Genevieve.d183502-c15.Car-Rental-Guide-Suppliers)
- [Avis Rental Cars in Ste Genevieve ](https://www.expedia.com/Avis-Car-Rentals-In-Ste-Genevieve.d183502-c41.Car-Rental-Guide-Suppliers)
- [Car rentals near Belgique ](https://www.expedia.com/Car-Rentals-In-Belgique.d553248635975859150.Car-Rental-Guide)
- [Car rentals near Perryville ](https://www.expedia.com/Car-Rentals-In-Perryville.d6134448.Car-Rental-Guide)
- [Hertz Rental Cars in Perryville ](https://www.expedia.com/Hertz-Car-Rentals-In-Perryville.d6134448-c40.Car-Rental-Guide-Suppliers)
- [Car rentals near Clearwater ](https://www.expedia.com/Car-Rentals-In-Clearwater.d553248635975868303.Car-Rental-Guide)
- [Car rentals near New Offenburg ](https://www.expedia.com/Car-Rentals-In-New-Offenburg.d3000349478.Car-Rental-Guide)
- [Car rentals near Crown Valley Winery ](https://www.expedia.com/Car-Rentals-In-Crown-Valley-Winery.d553248621532648473.Car-Rental-Guide)
- [Car rentals near Weingarten ](https://www.expedia.com/Car-Rentals-In-Weingarten.d553248635975847364.Car-Rental-Guide)

- [Ste Genevieve Vacation Rentals ](https://www.expedia.com/Ste-Genevieve-Vacation-Rentals.d183502.Travel-Guide-VacationRentals)
- [Perryville Vacation Rentals ](https://www.expedia.com/Perryville-Vacation-Rentals.d6134448.Travel-Guide-VacationRentals)
- [New Offenburg Vacation Rentals ](https://www.expedia.com/New-Offenburg-Vacation-Rentals.d3000349478.Travel-Guide-VacationRentals)