Title: The Best 5 Star Hotels in Florence, AL  | Expedia.com

[Florence Travel Guide](https://expedia.com/Florence.dx6057726)[Hotels in Florence](https://expedia.com/Florence-Hotels.d6057726.Travel-Guide-Hotels)[Vacation Rentals in Florence](https://expedia.com/Florence-Vacation-Rentals.d6057726.Travel-Guide-VacationRentals)[Flights to Florence](https://expedia.com/Cheap-Flights-To-Florence.d6057726.Travel-Guide-Flights)[Things to do in Florence](https://expedia.com/Things-To-Do-In-Florence.d6057726.Travel-Guide-Activities)[Car Rentals in Florence](https://expedia.com/Car-Rentals-In-Florence.d6057726.Car-Rental-Guide)[Florence Vacation Packages](https://expedia.com/Florence.d6057726.Destination-Travel-Guides)

![Florence showing a fountain and a square or plaza](https://images.trvl-media.com/place/6057726/facc2605-80f4-4ff3-85e6-f32b5617d28b.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Florence 5 Star Hotels

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## Florence and related destinations

- Florence
- Greenville
- Albany
- Meridian
- Richmond

Birthplace of W.C. Handy, the 'Father of the Blues,' offers a vibrant music scene and fascinating museum downtown. Stroll along the Tennessee River at McFarland Park, then explore Frank Lloyd Wright's Rosenbaum House with its striking mid-century design.

[See all hotels in Florence](https://www.expedia.com/Hotel-Search?startDate=2026-02-19&endDate=2026-02-20&adults=2&regionId=6057726)

![Florence showing a fountain and a square or plaza](https://images.trvl-media.com/place/6057726/facc2605-80f4-4ff3-85e6-f32b5617d28b.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high)

## Top Florence Hotel Reviews

## Find out more about Florence

Treat yourself on your next getaway. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Florence so popular in the last year. There's no reason to delay a getaway to Florence any longer. Furthermore, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. Book one of Expedia's luxurious 5-star hotels in Florence and get ready to enjoy the getaway of a lifetime. You deserve the great vacation you're dreaming about.

### 5-Star Hotels in Florence

Don't be afraid to request the best service from your hotel, along with the best conditions. Top-notch customer care, luxurious bedding, and deeply relaxing spa offerings are all on offer. You're sure to find exactly the accommodation you need. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to lay your head at night. What creature comforts do you want in your lodging? 24-hour room service, so you can order that chocolate soufflé© in the wee hours of the morning? A mud wrap treatment that will leave you feeling like a million bucks? Butler services? Whatever it is your heart desires, you're bound to find it here. 

Ready for experiences outside your hotel room? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Florence are the perfect place to relax after a busy day. Ready to learn more? Read the review section and see what previous visitors have said. You're sure to find exactly what you're looking for! 

### Make Your Escape

The results are in, and Florence 5-star hotels are the place to be when you book your next vacation. These beautiful hotels are highly rated by the guests who stay in them, and you're about to join their ranks. Expedia can help you land a great deal on accommodation. Don't put off your dream vacation any longer. Select one of Expedia's Florence 5-star hotels today and relax in total tranquility tomorrow.

## Frequently asked questions

### How much does it cost to stay in a 5-star hotel in Florence?

> - Search for the lowest price per night

### What makes a hotel 5 stars in Florence?

### Are there any 5-star all-inclusive resorts in Florence?

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