South Carolina may have travel restrictions in place due to COVID-19.

Find out moreOpens in new tab or window

Find 5 Star Hotels in Mount Pleasant, SC

Search over 1 million properties and 550 airlines worldwide

Members save 10% more on select hotels, cars, activities and vacation rentals. Sign up.

Free cancellation on most hotels. Because flexibility matters.

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mount Pleasant.

Still don't see what you're looking for?

See all properties in Mount Pleasant.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Treat yourself on your impending escape. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Mount Pleasant so popular in the last year. There's no reason to delay a getaway to Mount Pleasant any longer. We should also mention, the hotels in this area are known for customer service, so you know you'll want for nothing during your getaway. Book one of Expedia's luxurious 5-star hotels in Mount Pleasant and get ready to enjoy the getaway of a lifetime. You deserve the great vacation you're dreaming about.

5-Star Hotels in Mount Pleasant

Don't be afraid to be pampered during your trip, along with pristine rooms. Highly-rated eateries, top-notch customer care, and rejuvenating spa offerings are waiting for you. You're sure to find exactly the accommodation you need. We should also mention, the hotels in this area receive noteworthy marks for guest services, so you know you'll be looked after during your getaway. How do you want to relax? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A reflexology treatment that will leave you feeling outstanding? Butler services? Whatever it is your heart desires, you're bound to find it here. Want to see for yourself? Then explore the 793 reviews various guests have left on Expedia and get to know these places.

Yearning for experiences outside your hotel room? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Mount Pleasant are the perfect place to relax after an exciting day.

Your Getaway Starts Today

The results are in, and Mount Pleasant 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. It's time to indulge yourself -- Expedia can help you land a great deal on accommodation. Opt for one of Expedia's Mount Pleasant 5-star hotels today and dive into in total tranquility at your convenience.

More trip options

Recent reviews of Mount Pleasant hotels