Title: The Best 5 Star Hotels in Prenestino-Centocelle from $207 | Expedia.com [Prenestino-Centocelle Travel Guide](https://expedia.com/Rome-Prenestino-Centocelle.dx179103)[Vacation Rentals in Rome](https://expedia.com/Rome-Vacation-Rentals.d179899.Travel-Guide-VacationRentals)[Flights to Rome](https://expedia.com/Cheap-Flights-To-Rome.d179899.Travel-Guide-Flights)[Things to do in Rome](https://expedia.com/Things-To-Do-In-Rome.d179899.Travel-Guide-Activities)[Car Rentals in Prenestino-Centocelle](https://expedia.com/Car-Rentals-In-Prenestino-Centocelle.d179103.Car-Rental-Guide)[Prenestino-Centocelle Vacations](https://expedia.com/Prenestino-Centocelle.d179103.Destination-Travel-Guides) ![Vista aerea dell'acquedotto romano che attraversa una stada parallela alla via Casilina a Roma, in Italia. Le ville dei privati e alberi si sono sviluppati vicino i resti dell'antica Roma.](https://images.trvl-media.com/place/179103/9a7211ef-8663-419e-ae69-54208e3d8465.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/179103/9a7211ef-8663-419e-ae69-54208e3d8465.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Prenestino-Centocelle 5 Star Hotels Tonight [Mar 29 - Mar 30](https://www.expedia.com/Hotel-Search?regionId=179103&startDate=2026-03-29&endDate=2026-03-30&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 30 - Mar 31](https://www.expedia.com/Hotel-Search?regionId=179103&startDate=2026-03-30&endDate=2026-03-31&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=179103&startDate=2026-04-03&endDate=2026-04-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=179103&startDate=2026-04-10&endDate=2026-04-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Prenestino-Centocelle 5-star hotels ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/351e1592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/372ab6f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/7604df28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Navona) | Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/d3afe355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Raphaël – Relais & Châteaux [](https://www.expedia.com/Rome-Hotels-Bio-Hotel-Raphael-Relais-Chateaux.h3654.Hotel-Information) Rome City Centre 9.2/10 Wonderful (1,000 reviews) "Excellent staff and service. Property is in a great location. Walking distance to many of the famous sites and landmarks, street restaurants,etc. would stay there again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary $293 nightly $345 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Bio-Hotel-Raphael-Relais-Chateaux.h3654.Hotel-Information) ![Daily buffet breakfast for a fee](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/08478e2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/ae094d19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/e9e1e7d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast for a fee](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/2e3cd109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NH Collection Roma Palazzo Cinquecento [](https://www.expedia.com/Rome-Hotels-NH-Collection-Roma-Palazzo-Cinquecento.h12741260.Hotel-Information) Rome City Centre 9.0/10 Wonderful (1,005 reviews) "Great location and breakfast superb " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Stephen $374 nightly $434 total Apr 2 - Apr 3 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-NH-Collection-Roma-Palazzo-Cinquecento.h12741260.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/a3ebc34d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/57d1084d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed, Balcony | View from room](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/aadd1bed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/d2975d19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### W Rome [](https://www.expedia.com/Rome-Hotels-W-Rome.h69386994.Hotel-Information) Rome City Centre 9.6/10 Exceptional (212 reviews) "Amazing hotel, wonderful staff, convenience " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Anna $544 nightly $621 total Apr 28 - Apr 29 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-W-Rome.h69386994.Hotel-Information) ![Mellini Suite | Premium bedding, memory foam beds, free minibar, in-room safe](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/1510dcb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/da28f9f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/5a8f0c07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/6e4e2007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Six Senses Rome [](https://www.expedia.com/Rome-Hotels-Six-Senses-Rome.h83216106.Hotel-Information) Rome City Centre 9.6/10 Exceptional (65 reviews) "Beautiful hotel in a perfect location. The interior design is stunning, the staff wonderful and the little touches such as the infinite complimentary drinks and healthy snacks makes the stay a true pleasure." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Benjamin $1,330 nightly $1,486 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Six-Senses-Rome.h83216106.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/1444f82e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/w4148h2768x0y3-b519eb71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/428251da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/f2e5cacc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InterContinental Rome Ambasciatori Palace by IHG [](https://www.expedia.com/Rome-Hotels-InterContinental-Rome-Ambasciatori-Palace.h14529.Hotel-Information) Rome City Centre 9.6/10 Exceptional (177 reviews) "Great stay!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul $502 nightly $575 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-InterContinental-Rome-Ambasciatori-Palace.h14529.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/f57ce992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony view](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/220db8f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/56010301.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/eeec3cd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baglioni Hotel Regina - The Leading Hotels of the World [](https://www.expedia.com/Rome-Hotels-Baglioni-Hotel-Regina-The-Leading-Hotels-Of-The-World.h445130.Hotel-Information) Rome City Centre 9.0/10 Wonderful (523 reviews) "Rooms are clean, breakfast good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) cem $518 nightly $593 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Baglioni-Hotel-Regina-The-Leading-Hotels-Of-The-World.h445130.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/e3a42652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, cocktail bar, rooftop bar, lobby lounge](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/1dbc0992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Terrace (Prestige) | Terrace/patio](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/16daf83b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/d35a8401.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aleph Rome Hotel Curio Collection by Hilton [](https://www.expedia.com/Rome-Hotels-Aleph-Rome-Hotel-Curio-Collection-By-Hilton.h905949.Hotel-Information) Rome City Centre 9.4/10 Exceptional (478 reviews) "Spacious room, helpful staff with tour websites for guests. Hotel was in a very quiet area but extremely convenient location to walk to all of the historical sites and shopping. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erika $525 nightly $600 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Aleph-Rome-Hotel-Curio-Collection-By-Hilton.h905949.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/3d3ff7e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/3b6a96a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/d661ec21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/6d049010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel Rome Villa Borghese [](https://www.expedia.com/Rome-Hotels-Sofitel-Rome-Villa-Borghese.h9234.Hotel-Information) Rome City Centre 9.2/10 Wonderful (980 reviews) "Professional staff, luxurious surroundings, excellent location, very nice accommodations - all in all a great experience. " ![Sweden](https://a.travel-assets.com/egds/marks/flags/se.svg) Daniel $466 nightly $535 total Apr 29 - Apr 30 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Sofitel-Rome-Villa-Borghese.h9234.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/ea2f10b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/4253247e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, Italian cuisine](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/c8d17c77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/dcca70cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World [](https://www.expedia.com/Rome-Hotels-Anantara-Palazzo-Naiadi-Rome-Hotel-A-Leading-Hotel-Of-The-World.h907346.Hotel-Information) Rome City Centre 9.2/10 Wonderful (1,001 reviews) "incredible, no hotel compares to it. everything was perfect " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sana $673 nightly $763 total Apr 29 - Apr 30 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Anantara-Palazzo-Naiadi-Rome-Hotel-A-Leading-Hotel-Of-The-World.h907346.Hotel-Information) ![2 bars/lounges](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/2fccf7b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 38 per person)](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/6495ea6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/4bce46fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/c19872da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Collection Hotel, Roma Antica [](https://www.expedia.com/Rome-Hotels-Radisson-Collection-Hotel.h101129112.Hotel-Information) Rome City Centre 9.6/10 Exceptional (165 reviews) "Everything about the staff, location and food was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marco $382 nightly $443 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Radisson-Collection-Hotel.h101129112.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/w4000h2664x0y0-5e09c355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/c63db19c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/82baf38c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, cocktail bar, cocktail bar](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/62da7cbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Rome EDITION [](https://www.expedia.com/Rome-Hotels-The-Rome-Edition.h91518086.Hotel-Information) Rome City Centre 8.6/10 Excellent (39 reviews) "10/10 stay absolutely gorgeous hotel, great staff and handy location. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Katherine Haidee $768 nightly $868 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-The-Rome-Edition.h91518086.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/62c3e526.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/b96175a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 33 per person)](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/w2997h1997x0y0-e38173bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/ff430e96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hotel Palace Rome [](https://www.expedia.com/Rome-Hotels-Grand-Hotel-Palace.h663050.Hotel-Information) Rome City Centre 9.0/10 Wonderful (1,004 reviews) "Enjoyed our stay. Loved the outdoor patio in our room. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patti $233 nightly $279 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Grand-Hotel-Palace.h663050.Hotel-Information) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/cd0177d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, steam room, Turkish bath, body treatments, aromatherapy](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/18ffa144.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; alfresco dining](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/d359ea77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch LCD TV with satellite channels, TV](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/c33634b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Excelsior, Rome [](https://www.expedia.com/Rome-Hotels-The-Westin-Excelsior.h8002.Hotel-Information) Rome City Centre 8.2/10 Very Good (753 reviews) "Very clean, staff was very nice and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) len $509 nightly $583 total Apr 11 - Apr 12 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-The-Westin-Excelsior.h8002.Hotel-Information) ![Signature Suite, 1 King Bed (Planetarium Suite, Spa/Lounge Access) | Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/6912f8ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Suite, 1 King Bed (Planetarium Suite, Spa/Lounge Access) | Living area | 42-inch LED TV with satellite channels, TV, DVD player](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/9f549232.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, 3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/a94e4883.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/c1194e8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rome Cavalieri, A Waldorf Astoria Hotel [](https://www.expedia.com/Rome-Hotels-Rome-Cavalieri.h14941.Hotel-Information) Trionfale 9.2/10 Wonderful (1,000 reviews) "Amazing stay, incredible staff , awesome spa" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kory $376 nightly $436 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Rome-Cavalieri.h14941.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/8d6ed6e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/4dd2cbea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Suite, 2 Bedrooms, Sauna, City View | Premium bedding, minibar, in-room safe, soundproofing](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/0093daf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Open Suite | Premium bedding, minibar, in-room safe, soundproofing](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/43fc0905.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### U-Visionary Roma Hotel [](https://www.expedia.com/Rome-Hotels-U-Visionary-Roma-Hotel.h45167180.Hotel-Information) Rome City Centre 9.6/10 Exceptional (442 reviews) "Lovely staff, beautiful hotel, nice rooms and a great breakfast buffet. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Jessica $321 nightly $371 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-U-Visionary-Roma-Hotel.h45167180.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/d6369f38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite | Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/33904d48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/0c943386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite | Living area | 50-inch flat-screen TV with satellite channels](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/389a42b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Roma - The Leading Hotels of the World [](https://www.expedia.com/Rome-Hotels-Palazzo-Roma.h96484843.Hotel-Information) Rome City Centre 10/10 Exceptional (121 reviews) "Super nice hotel, great location and very friendly staff and manager. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ewing $466 nightly $536 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Palazzo-Roma.h96484843.Hotel-Information) ![Breakfast, lunch, dinner served; local and international cuisine ](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/7d6d9ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, bathrobes, slippers](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/f163216b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Suite, 1 King Bed, Ground Floor (Colosseum View) | View from room](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/4d277572.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/16472e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Manfredi – Small Luxury Hotels of the World [](https://www.expedia.com/Rome-Hotels-Palazzo-Manfredi-Small-Luxury-Hotels-Of-The-World.h1065602.Hotel-Information) Rome City Centre 9.0/10 Wonderful (652 reviews) "Absolutely loved this property. The location was perfect, room was spacious and comfortable. We loved ending our evenings in the court with a view of the Colosseum. Staff were friendly and helpful. Loved that it is a smaller property and felt cozy and like home. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brittney $383 nightly $445 total Apr 9 - Apr 10 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Palazzo-Manfredi-Small-Luxury-Hotels-Of-The-World.h1065602.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/7de39039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/fe27d45d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/0e5dc5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Room (Suite) | Premium bedding, down comforters, Select Comfort beds, minibar](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/w2997h1925x0y0-3b291246.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Ripetta [](https://www.expedia.com/Rome-Hotels-Residenza-Di-Ripetta.h2912498.Hotel-Information) Rome City Centre 9.8/10 Exceptional (118 reviews) "Nice property, great staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Natale $663 nightly $752 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Residenza-Di-Ripetta.h2912498.Hotel-Information) ![Lunch, dinner served; local and international cuisine, alfresco dining ](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/263507da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/94dbae85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/21d44ad0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 38.50 per person)](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/e71f6258.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Splendide Royal - The Leading Hotels of the World [](https://www.expedia.com/Rome-Hotels-Hotel-Splendide-Royal-The-Leading-Hotels-Of-The-World.h581053.Hotel-Information) Rome City Centre 9.4/10 Exceptional (1,000 reviews) "Great location. Beautiful space. Super friendly staff. A true Roman experience!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elvis $485 nightly $557 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Hotel-Splendide-Royal-The-Leading-Hotels-Of-The-World.h581053.Hotel-Information) ![Lunch and dinner served, international cuisine](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/9c429475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/a8f2970f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/58d8f9b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, international cuisine](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/c9448112.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sina Bernini Bristol, Autograph Collection [](https://www.expedia.com/Rome-Hotels-Sina-Bernini-Bristol.h445235.Hotel-Information) Rome City Centre 8.2/10 Very Good (547 reviews) "Amazing staff service and beautiful room " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samantha $489 nightly $560 total Apr 2 - Apr 3 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Sina-Bernini-Bristol.h445235.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Prenestino-Centocelle-Rome-Hotels.s50-n179103-0.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Prenestino-Centocelle-Rome-Hotels.s50-n179103-0.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Prenestino-Centocelle. ![Hotel Quirinale](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/1c2ed679_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Quirinale Via Nazionale 7 Rome RM $197 nightly $234 total Mar 30 - Mar 31 Total with taxes and fees 8.6/10 Excellent! (1,938 reviews) [](https://expedia.com/Rome-Hotels-Hotel-Quirinale.h1058.Hotel-Information) ![Hilton Garden Inn Rome Airport](https://images.trvl-media.com/lodging/2000000/1590000/1587200/1587154/78454e47_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hilton Garden Inn Rome Airport Via Vittorio Bragadin 2 Fiumicino RM $178 nightly $207 total Apr 12 - Apr 13 Total with taxes and fees 8.2/10 Very Good! (3,745 reviews) [](https://expedia.com/Rome-Hotels-Hilton-Garden-Inn-Rome-Airport.h1587154.Hotel-Information) ![Hilton Rome Airport](https://images.trvl-media.com/lodging/1000000/570000/564200/564180/ec19f7f6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hilton Rome Airport Via Arturo Ferrarin 2 Fiumicino RM $249 nightly $286 total Apr 20 - Apr 21 Total with taxes and fees 8.2/10 Very Good! (3,217 reviews) [](https://expedia.com/Rome-Hotels-Hilton-Rome-Airport.h564180.Hotel-Information) Still don't see what you're looking for? [See all properties in Prenestino-Centocelle.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F30%2F2026&endDate=3%2F31%2F2026®ionId=179103&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F30%2F2026&endDate=3%2F31%2F2026®ionId=179103&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F30%2F2026&endDate=3%2F31%2F2026®ionId=179103&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F30%2F2026&endDate=3%2F31%2F2026®ionId=179103&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F30%2F2026&endDate=3%2F31%2F2026®ionId=179103&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F30%2F2026&endDate=3%2F31%2F2026®ionId=179103&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Prenestino-Centocelle Hotel Reviews ## Find out more about Prenestino-Centocelle Ready for an incredible adventure? Add even more luxury on your next trip to Prenestino-Centocelle by treating yourself to the best of the best when it comes to accommodation. It's an ideal combination. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Prenestino-Centocelle so popular in the last year. There's no reason to delay a getaway to Prenestino-Centocelle any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Book one of Expedia's luxurious 5-star hotels in Prenestino-Centocelle and get ready to be pampered like never before. What are you waiting for? ### 5-Star Hotels in Prenestino-Centocelle You'll have a fantastic time at one of these 5-star hotels. Spa treatments, delicious meals, and attentive guest service are all waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What creature comforts do you want in your lodging? A rejuvenating facial treatment to help your cares fall away? A concierge to help you suggest the next attraction to visit? Comfortable beds, lip-smacking main courses, and even spectacular views...these hotels will astonish you. Ready for experiences outside your hotel room? Don't worry. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Prenestino-Centocelle are the perfect place to relax after a busy day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs. ### Your Getaway Starts Today The results are in, and Prenestino-Centocelle 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Your great getaway is just a mouse-click away -- Expedia can help you land a great deal on accommodation. Decide on one of the 5-star hotels in Prenestino-Centocelle today and relax in the lap of luxury tomorrow. ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Prenestino-Centocelle? > - Search for the lowest price per night from $207 ### What makes a hotel 5 stars in Prenestino-Centocelle? ### Are there any 5-star all-inclusive resorts in Prenestino-Centocelle? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Rome Hotels ](https://www.expedia.com/Rome-Hotels.d179899.Travel-Guide-Hotels) - [Hotels near Alessandrino ](https://www.expedia.com/Alessandrino-Rome-Hotels.0-n553248635976382843-0.Travel-Guide-Filter-Hotels) - [Hotels near Jubilee Church ](https://www.expedia.com/Jubilee-Church-Hotels.0-l553248621532499715-0.Travel-Guide-Filter-Hotels) - [Hotels near Prenestino-Labicano ](https://www.expedia.com/Prenestino-Labicano-Rome-Hotels.0-n6145021-0.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Prenestino-Labicano ](https://www.expedia.com/Prenestino-Labicano-Rome-Hotels-Luxury-Hotel.0-n6145021-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - 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