Title: The Best 5 Star Hotels in Prenestino-Centocelle from $193 | Expedia.com [Prenestino-Centocelle Travel Guide](https://expedia.com/Rome-Prenestino-Centocelle.dx179103)[Vacation Rentals in Rome](https://expedia.com/Rome-Vacation-Rentals.d179899.Travel-Guide-VacationRentals)[Flights to Rome](https://expedia.com/Cheap-Flights-To-Rome.d179899.Travel-Guide-Flights)[Things to do in Rome](https://expedia.com/Things-To-Do-In-Rome.d179899.Travel-Guide-Activities)[Car Rentals in Prenestino-Centocelle](https://expedia.com/Car-Rentals-In-Prenestino-Centocelle.d179103.Car-Rental-Guide)[Prenestino-Centocelle Vacations](https://expedia.com/Prenestino-Centocelle.d179103.Destination-Travel-Guides) ![Vista aerea dell'acquedotto romano che attraversa una stada parallela alla via Casilina a Roma, in Italia. Le ville dei privati e alberi si sono sviluppati vicino i resti dell'antica Roma.](https://images.trvl-media.com/place/179103/9a7211ef-8663-419e-ae69-54208e3d8465.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/179103/9a7211ef-8663-419e-ae69-54208e3d8465.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Prenestino-Centocelle 5 Star Hotels Tonight [Mar 23 - Mar 24](https://www.expedia.com/Hotel-Search?regionId=179103&startDate=2026-03-23&endDate=2026-03-24&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 24 - Mar 25](https://www.expedia.com/Hotel-Search?regionId=179103&startDate=2026-03-24&endDate=2026-03-25&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=179103&startDate=2026-03-27&endDate=2026-03-29&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=179103&startDate=2026-04-03&endDate=2026-04-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Prenestino-Centocelle 5-star hotels ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/351e1592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Navona) | Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/d3afe355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/7604df28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/c16a8c43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Raphaël – Relais & Châteaux [](https://www.expedia.com/Rome-Hotels-Bio-Hotel-Raphael-Relais-Chateaux.h3654.Hotel-Information) Rome City Centre 9.2/10 Wonderful (1,001 reviews) "Excellent staff and service. Property is in a great location. Walking distance to many of the famous sites and landmarks, street restaurants,etc. would stay there again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary $337 nightly $393 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Bio-Hotel-Raphael-Relais-Chateaux.h3654.Hotel-Information) ![Daily buffet breakfast for a fee](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/08478e2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/e9e1e7d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/7c35417f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/ae094d19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NH Collection Roma Palazzo Cinquecento [](https://www.expedia.com/Rome-Hotels-NH-Collection-Roma-Palazzo-Cinquecento.h12741260.Hotel-Information) Rome City Centre 9.0/10 Wonderful (1,002 reviews) "Great location and breakfast superb " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Stephen $358 nightly $417 total Apr 2 - Apr 3 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-NH-Collection-Roma-Palazzo-Cinquecento.h12741260.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/a3ebc34d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed, Balcony | View from room](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/aadd1bed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/e920a3f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/57d1084d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### W Rome [](https://www.expedia.com/Rome-Hotels-W-Rome.h69386994.Hotel-Information) Rome City Centre 9.6/10 Exceptional (210 reviews) "Amazing hotel, wonderful staff, convenience " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Anna $589 nightly $671 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-W-Rome.h69386994.Hotel-Information) ![Mellini Suite | Premium bedding, memory foam beds, free minibar, in-room safe](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/1510dcb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/6e4e2007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/5a8f0c07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mellini Suite | Premium bedding, memory foam beds, free minibar, in-room safe](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/w2330h3494x4y3-f53172b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Six Senses Rome [](https://www.expedia.com/Rome-Hotels-Six-Senses-Rome.h83216106.Hotel-Information) Rome City Centre 9.6/10 Exceptional (65 reviews) "Beautiful hotel in a perfect location. The interior design is stunning, the staff wonderful and the little touches such as the infinite complimentary drinks and healthy snacks makes the stay a true pleasure." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Benjamin $1,338 nightly $1,495 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Six-Senses-Rome.h83216106.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/1444f82e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/428251da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/w4148h2768x0y3-b519eb71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/f2e5cacc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InterContinental Rome Ambasciatori Palace by IHG [](https://www.expedia.com/Rome-Hotels-InterContinental-Rome-Ambasciatori-Palace.h14529.Hotel-Information) Rome City Centre 9.6/10 Exceptional (177 reviews) "Great stay!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul $505 nightly $579 total Apr 14 - Apr 15 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-InterContinental-Rome-Ambasciatori-Palace.h14529.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/f57ce992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/3cf992c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony view](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/220db8f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/56010301.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baglioni Hotel Regina - The Leading Hotels of the World [](https://www.expedia.com/Rome-Hotels-Baglioni-Hotel-Regina-The-Leading-Hotels-Of-The-World.h445130.Hotel-Information) Rome City Centre 9.0/10 Wonderful (522 reviews) "Rooms are clean, breakfast good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) cem $554 nightly $632 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Baglioni-Hotel-Regina-The-Leading-Hotels-Of-The-World.h445130.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/e3a42652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Terrace (Prestige) | Terrace/patio](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/16daf83b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/cbf73f06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/d35a8401.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aleph Rome Hotel Curio Collection by Hilton [](https://www.expedia.com/Rome-Hotels-Aleph-Rome-Hotel-Curio-Collection-By-Hilton.h905949.Hotel-Information) Rome City Centre 9.4/10 Exceptional (478 reviews) "Spacious room, helpful staff with tour websites for guests. Hotel was in a very quiet area but extremely convenient location to walk to all of the historical sites and shopping. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erika $465 nightly $535 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Aleph-Rome-Hotel-Curio-Collection-By-Hilton.h905949.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/3d3ff7e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/3b6a96a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/d661ec21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/518d9d6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel Rome Villa Borghese [](https://www.expedia.com/Rome-Hotels-Sofitel-Rome-Villa-Borghese.h9234.Hotel-Information) Rome City Centre 9.2/10 Wonderful (979 reviews) "Professional staff, luxurious surroundings, excellent location, very nice accommodations - all in all a great experience. " ![Sweden](https://a.travel-assets.com/egds/marks/flags/se.svg) Daniel $421 nightly $486 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Sofitel-Rome-Villa-Borghese.h9234.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/ea2f10b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, Italian cuisine](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/c8d17c77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/4253247e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/dcca70cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World [](https://www.expedia.com/Rome-Hotels-Anantara-Palazzo-Naiadi-Rome-Hotel-A-Leading-Hotel-Of-The-World.h907346.Hotel-Information) Rome City Centre 9.2/10 Wonderful (1,000 reviews) "incredible, no hotel compares to it. everything was perfect " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sana $738 nightly $835 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Anantara-Palazzo-Naiadi-Rome-Hotel-A-Leading-Hotel-Of-The-World.h907346.Hotel-Information) ![2 bars/lounges](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/2fccf7b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 38 per person)](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/6495ea6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/4bce46fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, Terrace, City View | Minibar, in-room safe, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/w3840h2557x0y0-11e439f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Collection Hotel, Roma Antica [](https://www.expedia.com/Rome-Hotels-Radisson-Collection-Hotel.h101129112.Hotel-Information) Rome City Centre 9.6/10 Exceptional (165 reviews) "Great staff clean rooms " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anthony $371 nightly $432 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Radisson-Collection-Hotel.h101129112.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/w4000h2664x0y0-5e09c355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/c63db19c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, cocktail bar, cocktail bar](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/62da7cbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/82baf38c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Rome EDITION [](https://www.expedia.com/Rome-Hotels-The-Rome-Edition.h91518086.Hotel-Information) Rome City Centre 8.6/10 Excellent (39 reviews) "10/10 stay absolutely gorgeous hotel, great staff and handy location. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Katherine Haidee $818 nightly $922 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-The-Rome-Edition.h91518086.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/62c3e526.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite | View from room](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/w2996h1998x0y0-c61cbfe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 33 per person)](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/w2997h1997x0y0-e38173bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/ff430e96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hotel Palace Rome [](https://www.expedia.com/Rome-Hotels-Grand-Hotel-Palace.h663050.Hotel-Information) Rome City Centre 9.0/10 Wonderful (1,003 reviews) "Enjoyed our stay. Loved the outdoor patio in our room. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patti $255 nightly $303 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Grand-Hotel-Palace.h663050.Hotel-Information) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/cd0177d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; alfresco dining](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/d359ea77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, steam room, Turkish bath, body treatments, aromatherapy](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/18ffa144.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/892ffcec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Excelsior, Rome [](https://www.expedia.com/Rome-Hotels-The-Westin-Excelsior.h8002.Hotel-Information) Rome City Centre 8.2/10 Very Good (753 reviews) "Very clean, staff was very nice and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) len $521 nightly $596 total Mar 27 - Mar 28 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-The-Westin-Excelsior.h8002.Hotel-Information) ![Signature Suite, 1 King Bed (Planetarium Suite, Spa/Lounge Access) | Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/6912f8ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Suite, 1 King Bed (Planetarium Suite, Spa/Lounge Access) | Living area | 42-inch LED TV with satellite channels, TV, DVD player](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/9f549232.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, 3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/a94e4883.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; international cuisine](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/086a304a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rome Cavalieri, A Waldorf Astoria Hotel [](https://www.expedia.com/Rome-Hotels-Rome-Cavalieri.h14941.Hotel-Information) Trionfale 9.2/10 Wonderful (1,001 reviews) "Amazing stay, incredible staff , awesome spa" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kory $355 nightly $413 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Rome-Cavalieri.h14941.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/8d6ed6e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Open Suite | Premium bedding, minibar, in-room safe, soundproofing](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/43fc0905.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/4dd2cbea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Suite, 2 Bedrooms, Sauna, City View | Premium bedding, minibar, in-room safe, soundproofing](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/0093daf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### U-Visionary Roma Hotel [](https://www.expedia.com/Rome-Hotels-U-Visionary-Roma-Hotel.h45167180.Hotel-Information) Rome City Centre 9.6/10 Exceptional (441 reviews) "Lovely staff, beautiful hotel, nice rooms and a great breakfast buffet. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Jessica $247 nightly $290 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-U-Visionary-Roma-Hotel.h45167180.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/d6369f38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/835db15d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/0c943386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite | Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/33904d48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Roma - The Leading Hotels of the World [](https://www.expedia.com/Rome-Hotels-Palazzo-Roma.h96484843.Hotel-Information) Rome City Centre 10/10 Exceptional (120 reviews) "Super nice hotel, great location and very friendly staff and manager. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ewing $469 nightly $539 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Palazzo-Roma.h96484843.Hotel-Information) ![Breakfast, lunch, dinner served; local and international cuisine ](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/7d6d9ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, bathrobes, slippers](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/f163216b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/16472e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; local and international cuisine ](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/358cbffb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Manfredi – Small Luxury Hotels of the World [](https://www.expedia.com/Rome-Hotels-Palazzo-Manfredi-Small-Luxury-Hotels-Of-The-World.h1065602.Hotel-Information) Rome City Centre 9.0/10 Wonderful (651 reviews) "Absolutely loved this property. The location was perfect, room was spacious and comfortable. We loved ending our evenings in the court with a view of the Colosseum. Staff were friendly and helpful. Loved that it is a smaller property and felt cozy and like home. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brittney $390 nightly $453 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Palazzo-Manfredi-Small-Luxury-Hotels-Of-The-World.h1065602.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/7de39039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Room (Suite) | Premium bedding, down comforters, Select Comfort beds, minibar](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/w2997h1925x0y0-3b291246.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/0e5dc5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/fe27d45d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Ripetta [](https://www.expedia.com/Rome-Hotels-Residenza-Di-Ripetta.h2912498.Hotel-Information) Rome City Centre 9.8/10 Exceptional (116 reviews) "Nice property, great staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Natale $554 nightly $633 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Residenza-Di-Ripetta.h2912498.Hotel-Information) ![Lunch, dinner served; local and international cuisine, alfresco dining ](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/263507da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/94dbae85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/21d44ad0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 38.50 per person)](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/e71f6258.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Splendide Royal - The Leading Hotels of the World [](https://www.expedia.com/Rome-Hotels-Hotel-Splendide-Royal-The-Leading-Hotels-Of-The-World.h581053.Hotel-Information) Rome City Centre 9.4/10 Exceptional (1,002 reviews) "Great location. Beautiful space. Super friendly staff. A true Roman experience!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elvis $520 nightly $595 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Hotel-Splendide-Royal-The-Leading-Hotels-Of-The-World.h581053.Hotel-Information) ![Lunch and dinner served, international cuisine](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/9c429475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/58d8f9b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/eacf5f04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, international cuisine](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/c9448112.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sina Bernini Bristol, Autograph Collection [](https://www.expedia.com/Rome-Hotels-Sina-Bernini-Bristol.h445235.Hotel-Information) Rome City Centre 8.2/10 Very Good (547 reviews) "Amazing staff service and beautiful room " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samantha $491 nightly $564 total Apr 2 - Apr 3 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Sina-Bernini-Bristol.h445235.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Prenestino-Centocelle-Rome-Hotels.s50-n179103-0.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Prenestino-Centocelle-Rome-Hotels.s50-n179103-0.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Prenestino-Centocelle. ![Hotel Quirinale](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/1c2ed679_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Quirinale Via Nazionale 7 Rome RM $199 nightly $236 total Apr 6 - Apr 7 Total with taxes and fees 8.6/10 Excellent! (1,943 reviews) [](https://expedia.com/Rome-Hotels-Hotel-Quirinale.h1058.Hotel-Information) ![Hilton Garden Inn Rome Airport](https://images.trvl-media.com/lodging/2000000/1590000/1587200/1587154/78454e47_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hilton Garden Inn Rome Airport Via Vittorio Bragadin 2 Fiumicino RM $165 nightly $193 total Mar 30 - Mar 31 Total with taxes and fees 8.2/10 Very Good! (3,743 reviews) [](https://expedia.com/Rome-Hotels-Hilton-Garden-Inn-Rome-Airport.h1587154.Hotel-Information) ![Hilton Rome Airport](https://images.trvl-media.com/lodging/1000000/570000/564200/564180/ec19f7f6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hilton Rome Airport Via Arturo Ferrarin 2 Fiumicino RM $261 nightly $298 total Apr 6 - Apr 7 Total with taxes and fees 8.2/10 Very Good! (3,223 reviews) [](https://expedia.com/Rome-Hotels-Hilton-Rome-Airport.h564180.Hotel-Information) Still don't see what you're looking for? [See all properties in Prenestino-Centocelle.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F24%2F2026&endDate=3%2F25%2F2026®ionId=179103&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F24%2F2026&endDate=3%2F25%2F2026®ionId=179103&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F24%2F2026&endDate=3%2F25%2F2026®ionId=179103&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F24%2F2026&endDate=3%2F25%2F2026®ionId=179103&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F24%2F2026&endDate=3%2F25%2F2026®ionId=179103&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F24%2F2026&endDate=3%2F25%2F2026®ionId=179103&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Prenestino-Centocelle Hotel Reviews ## Find out more about Prenestino-Centocelle Ready for an incredible adventure? Add even more luxury on your next trip to Prenestino-Centocelle by treating yourself to the best of the best when it comes to accommodation. It's an ideal combination. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Prenestino-Centocelle so popular in the last year. There's no reason to delay a getaway to Prenestino-Centocelle any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Book one of Expedia's luxurious 5-star hotels in Prenestino-Centocelle and get ready to be pampered like never before. What are you waiting for? ### 5-Star Hotels in Prenestino-Centocelle You'll have a fantastic time at one of these 5-star hotels. Spa treatments, delicious meals, and attentive guest service are all waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What creature comforts do you want in your lodging? A rejuvenating facial treatment to help your cares fall away? A concierge to help you suggest the next attraction to visit? Comfortable beds, lip-smacking main courses, and even spectacular views...these hotels will astonish you. Ready for experiences outside your hotel room? Don't worry. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Prenestino-Centocelle are the perfect place to relax after a busy day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs. ### Your Getaway Starts Today The results are in, and Prenestino-Centocelle 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Your great getaway is just a mouse-click away -- Expedia can help you land a great deal on accommodation. Decide on one of the 5-star hotels in Prenestino-Centocelle today and relax in the lap of luxury tomorrow. ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Prenestino-Centocelle? > - Search for the lowest price per night from $193 ### What makes a hotel 5 stars in Prenestino-Centocelle? ### Are there any 5-star all-inclusive resorts in Prenestino-Centocelle? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Rome Hotels ](https://www.expedia.com/Rome-Hotels.d179899.Travel-Guide-Hotels) - [Hotels near Alessandrino ](https://www.expedia.com/Alessandrino-Rome-Hotels.0-n553248635976382843-0.Travel-Guide-Filter-Hotels) - [Hotels near Jubilee Church ](https://www.expedia.com/Jubilee-Church-Hotels.0-l553248621532499715-0.Travel-Guide-Filter-Hotels) - [Hotels near Prenestino-Labicano ](https://www.expedia.com/Prenestino-Labicano-Rome-Hotels.0-n6145021-0.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Prenestino-Labicano ](https://www.expedia.com/Prenestino-Labicano-Rome-Hotels-Luxury-Hotel.0-n6145021-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - 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