Title: The Best 5 Star Hotels in Rome Historic Centre from $226 | Expedia.com

[Rome Historic Centre Travel Guide](https://expedia.com/Rome-Rome-Historic-Centre.dx6200441)[Vacation Rentals in Rome](https://expedia.com/Rome-Vacation-Rentals.d179899.Travel-Guide-VacationRentals)[Flights to Rome](https://expedia.com/Cheap-Flights-To-Rome.d179899.Travel-Guide-Flights)[Things to do in Rome](https://expedia.com/Things-To-Do-In-Rome.d179899.Travel-Guide-Activities)[Car Rentals in Rome Historic Centre](https://expedia.com/Car-Rentals-In-Rome-Historic-Centre.d6200441.Car-Rental-Guide)[Rome Historic Centre Vacations](https://expedia.com/Rome-Historic-Centre.d6200441.Destination-Travel-Guides)

![Rome Historic Centre showing a statue or sculpture, a fountain and a square or plaza](https://images.trvl-media.com/place/6200441/57c34773-acbf-4b05-b5e7-9b3e692babe1.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6200441/57c34773-acbf-4b05-b5e7-9b3e692babe1.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Rome Historic Centre 5 Star Hotels

Tonight

[Mar 25 - Mar 26](https://www.expedia.com/Hotel-Search?regionId=6200441&startDate=2026-03-25&endDate=2026-03-26&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 26 - Mar 27](https://www.expedia.com/Hotel-Search?regionId=6200441&startDate=2026-03-26&endDate=2026-03-27&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=6200441&startDate=2026-03-27&endDate=2026-03-29&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6200441&startDate=2026-04-03&endDate=2026-04-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Rome Historic Centre 5-star hotels

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/351e1592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/7604df28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/c16a8c43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite (Navona) | Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/d3afe355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Raphaël – Relais & Châteaux

[](https://www.expedia.com/Rome-Hotels-Bio-Hotel-Raphael-Relais-Chateaux.h3654.Hotel-Information)

Rome City Centre

9.2/10

Wonderful

(1,002 reviews)

"Excellent staff and service. Property is in a great location. Walking distance to many of the famous sites and landmarks, street restaurants,etc. would stay there again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gary

$338 nightly

$395 total

Mar 26 - Mar 27

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Bio-Hotel-Raphael-Relais-Chateaux.h3654.Hotel-Information)

![Daily buffet breakfast for a fee](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/08478e2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/7c35417f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/ae094d19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily buffet breakfast for a fee](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/2e3cd109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### NH Collection Roma Palazzo Cinquecento

[](https://www.expedia.com/Rome-Hotels-NH-Collection-Roma-Palazzo-Cinquecento.h12741260.Hotel-Information)

Rome City Centre

9.0/10

Wonderful

(1,000 reviews)

"Great location and breakfast superb "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Stephen

$365 nightly

$425 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-NH-Collection-Roma-Palazzo-Cinquecento.h12741260.Hotel-Information)

![Meeting facility](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/a3ebc34d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio, 1 King Bed, Balcony | View from room](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/aadd1bed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/d2975d19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/57d1084d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### W Rome

[](https://www.expedia.com/Rome-Hotels-W-Rome.h69386994.Hotel-Information)

Rome City Centre

9.6/10

Exceptional

(211 reviews)

"Amazing hotel, wonderful staff, convenience "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Anna

$591 nightly

$674 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-W-Rome.h69386994.Hotel-Information)

![Mellini Suite | Premium bedding, memory foam beds, free minibar, in-room safe](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/1510dcb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/da28f9f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/6e4e2007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Mellini Suite | Premium bedding, memory foam beds, free minibar, in-room safe](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/w2330h3494x4y3-f53172b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Six Senses Rome

[](https://www.expedia.com/Rome-Hotels-Six-Senses-Rome.h83216106.Hotel-Information)

Rome City Centre

9.6/10

Exceptional

(65 reviews)

"Beautiful hotel in a perfect location. The interior design is stunning, the staff wonderful and the little touches such as the infinite complimentary drinks and healthy snacks makes the stay a true pleasure."

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Benjamin

$1,343 nightly

$1,500 total

Apr 1 - Apr 2

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Six-Senses-Rome.h83216106.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/1444f82e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/w6377h4246x0y5-6e366eaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/f2e5cacc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/428251da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### InterContinental Rome Ambasciatori Palace by IHG

[](https://www.expedia.com/Rome-Hotels-InterContinental-Rome-Ambasciatori-Palace.h14529.Hotel-Information)

Rome City Centre

9.6/10

Exceptional

(177 reviews)

"Great stay!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Paul

$507 nightly

$581 total

Apr 6 - Apr 7

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-InterContinental-Rome-Ambasciatori-Palace.h14529.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/f57ce992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/3cf992c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/eeec3cd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/56010301.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baglioni Hotel Regina - The Leading Hotels of the World

[](https://www.expedia.com/Rome-Hotels-Baglioni-Hotel-Regina-The-Leading-Hotels-Of-The-World.h445130.Hotel-Information)

Rome City Centre

9.0/10

Wonderful

(522 reviews)

"Rooms are clean, breakfast good"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

cem

$570 nightly

$650 total

Apr 7 - Apr 8

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Baglioni-Hotel-Regina-The-Leading-Hotels-Of-The-World.h445130.Hotel-Information)

![Interior entrance](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/e3a42652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Terrace (Prestige) | Terrace/patio](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/16daf83b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/d35a8401.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, cocktail bar, rooftop bar, lobby lounge](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/1dbc0992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aleph Rome Hotel Curio Collection by Hilton

[](https://www.expedia.com/Rome-Hotels-Aleph-Rome-Hotel-Curio-Collection-By-Hilton.h905949.Hotel-Information)

Rome City Centre

9.4/10

Exceptional

(478 reviews)

"Spacious room, helpful staff with tour websites for guests. Hotel was in a very quiet area but extremely convenient location to walk to all of the historical sites and shopping. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Erika

$486 nightly

$557 total

Mar 27 - Mar 28

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Aleph-Rome-Hotel-Curio-Collection-By-Hilton.h905949.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/3d3ff7e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/518d9d6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, minibar, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/6d049010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/3b6a96a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sofitel Rome Villa Borghese

[](https://www.expedia.com/Rome-Hotels-Sofitel-Rome-Villa-Borghese.h9234.Hotel-Information)

Rome City Centre

9.2/10

Wonderful

(979 reviews)

"Professional staff, luxurious surroundings, excellent location, very nice accommodations - all in all a great experience. "

![Sweden](https://a.travel-assets.com/egds/marks/flags/se.svg)

Daniel

$486 nightly

$557 total

Mar 26 - Mar 27

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Sofitel-Rome-Villa-Borghese.h9234.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/ea2f10b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/3ece677b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/dcca70cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/4253247e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

[](https://www.expedia.com/Rome-Hotels-Anantara-Palazzo-Naiadi-Rome-Hotel-A-Leading-Hotel-Of-The-World.h907346.Hotel-Information)

Rome City Centre

9.2/10

Wonderful

(1,000 reviews)

"incredible, no hotel compares to it. everything was perfect "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sana

$741 nightly

$838 total

Apr 6 - Apr 7

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Anantara-Palazzo-Naiadi-Rome-Hotel-A-Leading-Hotel-Of-The-World.h907346.Hotel-Information)

![2 bars/lounges](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/2fccf7b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/4bce46fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, Terrace, City View | Minibar, in-room safe, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/w3840h2557x0y0-11e439f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/c19872da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Radisson Collection Hotel, Roma Antica

[](https://www.expedia.com/Rome-Hotels-Radisson-Collection-Hotel.h101129112.Hotel-Information)

Rome City Centre

9.6/10

Exceptional

(165 reviews)

"Great staff clean rooms "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anthony

$414 nightly

$479 total

Apr 6 - Apr 7

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Radisson-Collection-Hotel.h101129112.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/w4000h2664x0y0-5e09c355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bars/lounges, cocktail bar, cocktail bar](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/62da7cbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/82baf38c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/w4000h2664x0y0-eea1b5ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Rome EDITION

[](https://www.expedia.com/Rome-Hotels-The-Rome-Edition.h91518086.Hotel-Information)

Rome City Centre

8.6/10

Excellent

(39 reviews)

"10/10 stay absolutely gorgeous hotel, great staff and handy location. "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Katherine Haidee

$821 nightly

$926 total

Apr 7 - Apr 8

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-The-Rome-Edition.h91518086.Hotel-Information)

![Property entrance](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/62c3e526.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Room | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/ff430e96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily buffet breakfast (EUR 33 per person)](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/w2997h1997x0y0-e38173bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite | View from room](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/w2996h1998x0y0-c61cbfe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grand Hotel Palace Rome

[](https://www.expedia.com/Rome-Hotels-Grand-Hotel-Palace.h663050.Hotel-Information)

Rome City Centre

9.0/10

Wonderful

(1,004 reviews)

"Enjoyed our stay. Loved the outdoor patio in our room. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Patti

$262 nightly

$311 total

Mar 26 - Mar 27

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Grand-Hotel-Palace.h663050.Hotel-Information)

![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/cd0177d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sauna, steam room, Turkish bath, body treatments, aromatherapy](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/18ffa144.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch LCD TV with satellite channels, TV](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/c33634b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; alfresco dining](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/d359ea77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Westin Excelsior, Rome

[](https://www.expedia.com/Rome-Hotels-The-Westin-Excelsior.h8002.Hotel-Information)

Rome City Centre

8.2/10

Very Good

(753 reviews)

"Very clean, staff was very nice and helpful."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

len

$523 nightly

$598 total

Mar 27 - Mar 28

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-The-Westin-Excelsior.h8002.Hotel-Information)

![Rooftop terrace](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/8d6ed6e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/4dd2cbea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Signature Suite, 2 Bedrooms, Sauna, City View | Premium bedding, minibar, in-room safe, soundproofing](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/0093daf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/b0d9d12e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### U-Visionary Roma Hotel

[](https://www.expedia.com/Rome-Hotels-U-Visionary-Roma-Hotel.h45167180.Hotel-Information)

Rome City Centre

9.6/10

Exceptional

(441 reviews)

"Lovely staff, beautiful hotel, nice rooms and a great breakfast buffet. "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Jessica

$254 nightly

$297 total

Mar 26 - Mar 27

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-U-Visionary-Roma-Hotel.h45167180.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/d6369f38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Suite | Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/33904d48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/835db15d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Staircase](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/0c943386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Palazzo Roma - The Leading Hotels of the World

[](https://www.expedia.com/Rome-Hotels-Palazzo-Roma.h96484843.Hotel-Information)

Rome City Centre

10/10

Exceptional

(120 reviews)

"Super nice hotel, great location and very friendly staff and manager. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ewing

$470 nightly

$541 total

Apr 12 - Apr 13

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Palazzo-Roma.h96484843.Hotel-Information)

![Breakfast, lunch, dinner served; local and international cuisine ](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/7d6d9ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free toiletries, hair dryer, bathrobes, slippers](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/f163216b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; local and international cuisine ](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/358cbffb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Panoramic Suite, 1 King Bed, Ground Floor (Colosseum View) | View from room](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/4d277572.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Palazzo Manfredi – Small Luxury Hotels of the World

[](https://www.expedia.com/Rome-Hotels-Palazzo-Manfredi-Small-Luxury-Hotels-Of-The-World.h1065602.Hotel-Information)

Rome City Centre

9.0/10

Wonderful

(652 reviews)

"Absolutely loved this property. The location was perfect, room was spacious and comfortable. We loved ending our evenings in the court with a view of the Colosseum. Staff were friendly and helpful. Loved that it is a smaller property and felt cozy and like home. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brittney

$453 nightly

$522 total

Mar 31 - Apr 1

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Palazzo-Manfredi-Small-Luxury-Hotels-Of-The-World.h1065602.Hotel-Information)

![Lobby lounge](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/7de39039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Room (Suite) | Premium bedding, down comforters, Select Comfort beds, minibar](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/w2997h1925x0y0-3b291246.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop terrace](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/fe27d45d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/0e5dc5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Palazzo Ripetta

[](https://www.expedia.com/Rome-Hotels-Residenza-Di-Ripetta.h2912498.Hotel-Information)

Rome City Centre

9.8/10

Exceptional

(116 reviews)

"Nice property, great staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Natale

$556 nightly

$635 total

Mar 31 - Apr 1

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Residenza-Di-Ripetta.h2912498.Hotel-Information)

![Lunch, dinner served; local and international cuisine, alfresco dining ](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/263507da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily buffet breakfast (EUR 38.50 per person)](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/e71f6258.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/93b850c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/94dbae85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Splendide Royal - The Leading Hotels of the World

[](https://www.expedia.com/Rome-Hotels-Hotel-Splendide-Royal-The-Leading-Hotels-Of-The-World.h581053.Hotel-Information)

Rome City Centre

9.4/10

Exceptional

(1,002 reviews)

"Great location. Beautiful space. Super friendly staff. A true Roman experience!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Elvis

$532 nightly

$609 total

Apr 14 - Apr 15

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Hotel-Splendide-Royal-The-Leading-Hotels-Of-The-World.h581053.Hotel-Information)

![Lunch and dinner served, international cuisine](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/9c429475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lunch and dinner served, international cuisine](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/c9448112.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/a8f2970f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/58d8f9b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sina Bernini Bristol, Autograph Collection

[](https://www.expedia.com/Rome-Hotels-Sina-Bernini-Bristol.h445235.Hotel-Information)

Rome City Centre

8.2/10

Very Good

(547 reviews)

"Amazing staff service and beautiful room "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Samantha

$493 nightly

$566 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Sina-Bernini-Bristol.h445235.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/2000000/1600000/1595400/1595380/71794438.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop bar](https://images.trvl-media.com/lodging/2000000/1600000/1595400/1595380/efc5c2f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite (Sakura) | Living room | LCD TV, pay movies](https://images.trvl-media.com/lodging/2000000/1600000/1595400/1595380/w2997h1998x0y0-cb012a9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop terrace](https://images.trvl-media.com/lodging/2000000/1600000/1595400/1595380/d0885d14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Nobu Hotel Roma

[](https://www.expedia.com/Rome-Hotels-Nobu-Hotel-Roma.h1595380.Hotel-Information)

Rome City Centre

9.0/10

Wonderful

(16 reviews)

"Great location. New construction and hotel"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kristian

$644 nightly

$732 total

Mar 25 - Mar 26

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Nobu-Hotel-Roma.h1595380.Hotel-Information)

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## Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Rome Historic Centre.

![Hotel Quirinale](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/1c2ed679_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hotel Quirinale

Via Nazionale 7 Rome RM

$190 nightly

$226 total

Apr 6 - Apr 7

Total with taxes and fees

8.6/10 Excellent! (1,933 reviews)

[](https://expedia.com/Rome-Hotels-Hotel-Quirinale.h1058.Hotel-Information)

![Gioberti Hotel](https://images.trvl-media.com/lodging/1000000/80000/70700/70681/432a0390_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Gioberti Hotel

Via Gioberti, 20 Rome RM

$190 nightly

$227 total

Mar 26 - Mar 27

Total with taxes and fees

8.4/10 Very Good! (1,526 reviews)

[](https://expedia.com/Rome-Hotels-Gioberti-Hotel.h70681.Hotel-Information)

![Hotel Artemide](https://images.trvl-media.com/lodging/1000000/50000/45900/45856/dccbfa6d_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hotel Artemide

Via Nazionale 22 Rome RM

$219 nightly

$258 total

Mar 29 - Mar 30

Total with taxes and fees

9.8/10 Exceptional! (1,006 reviews)

[](https://expedia.com/Rome-Hotels-Hotel-Artemide.h45856.Hotel-Information)

Still don't see what you're looking for?

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[Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F25%2F2026&endDate=3%2F26%2F2026&regionId=6200441&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F25%2F2026&endDate=3%2F26%2F2026&regionId=6200441&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F25%2F2026&endDate=3%2F26%2F2026&regionId=6200441&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F25%2F2026&endDate=3%2F26%2F2026&regionId=6200441&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F25%2F2026&endDate=3%2F26%2F2026&regionId=6200441&star=50&star=50&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Learn more about Rome Historic Centre

Visit the center of Italy’s capital and enjoy traditional Italian food. Relax in old bars and see some of the city’s famous historic sites.

[See all hotels in Rome Historic Centre](https://www.expedia.com/Hotel-Search?startDate=2026-04-07&endDate=2026-04-08&adults=2&regionId=6200441)

![Rome Historic Centre showing a statue or sculpture, a fountain and a square or plaza](https://images.trvl-media.com/place/6200441/57c34773-acbf-4b05-b5e7-9b3e692babe1.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high)

## Top Rome Historic Centre Hotel Reviews

## Find out more about Rome Historic Centre

You enjoy the finer things in life, both at home and on vacation. Add an extra layer of enjoyment on your next trip to Rome Historic Centre by treating yourself to the best of the best when it comes to accommodation. It's an ideal fusion. There's no reason to delay a getaway to Rome Historic Centre any longer. You'll join the multitudes of vacationers who have made Rome Historic Centre so fashionable in the last year. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Our 5-star hotels in Rome Historic Centre are the perfect places to relax in when you really need to escape.

### Book the Best Rome Historic Centre 5-Star Hotels

You'll have a fantastic time at one of these 5-star hotels. Exceptional service, delicious meals, and one-on-one attention are all at your fingertips. You're sure to find exactly the accommodation you need. You'll also enjoy a high standard of care and meticulous guest relations, so get ready to kick back and indulge. What creature comforts do you want in your lodging? 24-hour room service, so you can order that Turkish coffee in the wee hours of the morning? A reflexology treatment that will leave you feeling great? Butler services? Whatever it is your heart desires, you're bound to find it here. 

You won't sleep and order room service the entire time, though. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Rome Historic Centre are waiting for you to rest up after a busy day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs. 

### Your Getaway Starts Today

The results are in, and Rome Historic Centre 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. This is a great time to find 5-star hotel deals in @region! It's time to indulge yourself. Decide on one of our Rome Historic Centre 5-star hotels today and decompress in total tranquility tomorrow.

## Frequently asked questions

### What are the best 5-star hotels in Rome Historic Centre?

### How much does it cost to stay in a 5-star hotel in Rome Historic Centre?

> - Search for the lowest price per night from $226

### What makes a hotel 5 stars in Rome Historic Centre?

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- [Lapis Niger ](https://www.expedia.com/Lapis-Niger-Rome-City-Centre.d553248621533001929.Vacation-Attraction)
- [Visit Campitelli ](https://www.expedia.com/Rome-Campitelli.dx6185350)
- [Church of Santa Maria Antiqua ](https://www.expedia.com/Church-Of-Santa-Maria-Antiqua-Rome-City-Centre.d553248621532500852.Vacation-Attraction)
- [Colonna di Foca ](https://www.expedia.com/Colonna-Di-Foca-Rome-City-Centre.d553248621533001945.Vacation-Attraction)
- [Arch of Titus ](https://www.expedia.com/Arch-Of-Titus-Rome-City-Centre.d6073984.Vacation-Attraction)
- [Mamertine Prison ](https://www.expedia.com/Mamertine-Prison-Rome-City-Centre.d6074046.Vacation-Attraction)
- [Arch of Septimius Severus ](https://www.expedia.com/Arch-Of-Septimius-Severus-Rome-City-Centre.d6073982.Vacation-Attraction)
- [Basilica Giulia ](https://www.expedia.com/Basilica-Giulia-Rome-City-Centre.d553248621532501646.Vacation-Attraction)
- [Farnese Gardens ](https://www.expedia.com/Farnese-Gardens-Rome-City-Centre.d6074012.Vacation-Attraction)
- [Temple of Saturn ](https://www.expedia.com/Temple-Of-Saturn-Rome-City-Centre.d6074152.Vacation-Attraction)
- [Porticus Deorum Consentium ](https://www.expedia.com/Porticus-Deorum-Consentium-Rome-City-Centre.d553248621533001932.Vacation-Attraction)
- [Palazzo Senatorio ](https://www.expedia.com/Palazzo-Senatorio-Rome-City-Centre.d553248621533001936.Vacation-Attraction)
- [Church of Santa Maria dei Monti ](https://www.expedia.com/Church-Of-Santa-Maria-Dei-Monti-Rome-City-Centre.d6175847.Vacation-Attraction)
- [Trajan's Forum ](https://www.expedia.com/Trajans-Forum-Rome-City-Centre.d6074020.Vacation-Attraction)
- [Palatine Hill ](https://www.expedia.com/Palatine-Hill-Rome-City-Centre.d6147056.Vacation-Attraction)
- [Il Ninfeo degli Annibaldi ](https://www.expedia.com/Il-Ninfeo-Degli-Annibaldi-Rome-City-Centre.d553248621532501678.Vacation-Attraction)
- [Piazza del Campidoglio ](https://www.expedia.com/Piazza-Del-Campidoglio-Rome-City-Centre.d6074096.Vacation-Attraction)
- [Visit Lazio ](https://www.expedia.com/Lazio.dx6048637)
- [Torre delle Milizie ](https://www.expedia.com/Torre-Delle-Milizie-Rome-City-Centre.d6074156.Vacation-Attraction)
- [Palazzo Nuovo ](https://www.expedia.com/Palazzo-Nuovo-Rome-City-Centre.d553248621532501648.Vacation-Attraction)
- [Complesso del Vittoriano ](https://www.expedia.com/Complesso-Del-Vittoriano-Rome-City-Centre.d553248621533001933.Vacation-Attraction)
- [Province of Rome Vacations ](https://www.expedia.com/Province-Of-Rome.d6051850.Destination-Travel-Guides)
- [Arch of Constantine ](https://www.expedia.com/Arch-Of-Constantine-Rome-City-Centre.d6073980.Vacation-Attraction)
- [Lazio Vacations ](https://www.expedia.com/Lazio.d6048637.Destination-Travel-Guides)
- [Visit Province of Rome ](https://www.expedia.com/Province-Of-Rome.dx6051850)

- [Car rentals near Curia Julia ](https://www.expedia.com/Car-Rentals-In-Curia-Julia.d553248621532500824.Car-Rental-Guide)
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- [Car rentals near Rome ](https://www.expedia.com/Car-Rentals-In-Rome.d179899.Car-Rental-Guide)
- [Car rentals near Province of Rome ](https://www.expedia.com/Destinations-In-Province-Of-Rome.d6051850.Car-Rental-Destinations)
- [Car rentals near Lazio ](https://www.expedia.com/Destinations-In-Lazio.d6048637.Car-Rental-Destinations)

- [Province of Rome Vacation Rentals ](https://www.expedia.com/Destinations-In-Province-Of-Rome.d6051850.Vacation-Rental-Destinations)

- [Things to do in Lazio ](https://www.expedia.com/Things-To-Do-In-Lazio.d6048637.Travel-Guide-Activities)
- [Things to do in Province of Rome ](https://www.expedia.com/Things-To-Do-In-Province-Of-Rome.d6051850.Travel-Guide-Activities)

- [Book Hotels in Rome Historic Centre on Expedia.it ](https://www.expedia.it/5Stelle-Centro-Storico-Di-Roma-Roma-Hotel.s50-n6200441-0.Guida-Viaggi-Filtro-Hotel)