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Find 5 Star Hotels in San Francisco from $87

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Compare San Francisco 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Outdoor pool, sun loungers
Hotel Riu Plaza Panama
5.0 star property
9.0 out of 10, Wonderful, (2434)
"This hotel was very clean. There are three restaurants in it. The food was excellent. I had to call the housekeeping staff several times to get a laundry bag. I had to call Reception to get the hand soap and shower gel replaced when both obviously needed a refill. "
The price is $115
$127 total
includes taxes & fees
May 29 - May 30
Hotel Riu Plaza Panama
4 outdoor pools, cabanas (surcharge), pool umbrellas
JW Marriott Panama
5.0 star property
8.8 out of 10, Excellent, (1001)
"Nice place to stay in Panama"
The price is $183
$202 total
includes taxes & fees
Jun 16 - Jun 17
JW Marriott Panama
Marvelous Suite, Suite, 1 King Bed, City View | In-room safe, blackout drapes, iron/ironing board
W Panama
5.0 star property
8.8 out of 10, Excellent, (988)
"Nice place to stay in Panama"
The price is $169
$186 total
includes taxes & fees
Jun 7 - Jun 8
W Panama
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Outdoor pool, pool umbrellas, sun loungers
Waldorf Astoria Panama
5.0 star property
9.0 out of 10, Wonderful, (940)
"Overall nice staff and property but could use some upgrades"
The price is $183
$202 total
includes taxes & fees
Jun 7 - Jun 8
Waldorf Astoria Panama
Exterior
Sofitel Legend Casco Viejo, Panama City
5.0 star property
9.8 out of 10, Exceptional, (220)
"Lo máximo !!"
The price is $293
$322 total
includes taxes & fees
Jun 2 - Jun 3
Sofitel Legend Casco Viejo, Panama City
Outdoor pool
Hilton Panama
5.0 star property
8.8 out of 10, Excellent, (1000)
"The property and trips were excellent. But the transportation to and from airport was exceedingly poor. We paid extra for the premier car but the first car to the hotel was decrepit, and the second car to the airport turned up late and had other passengers.- it was supposed to be a private transfer. We were not pleased considerign we paid for the premium service"
The price is $191
$210 total
includes taxes & fees
Jun 15 - Jun 16
Hilton Panama
3 outdoor pools, pool umbrellas, sun loungers
The Westin Playa Bonita Panama
5.0 star property
8.0 out of 10, Very Good, (906)
"I love that the property is very luxurious and service is perfect. Only problem I have is misinformation on all inclusive package. I expected all inclusive to be part of my itinerary. I wanted to have everything included along with my stay. Abd nobody mentioned us about excursions either. "
The price is $152
$167 total
includes taxes & fees
Jun 14 - Jun 15
The Westin Playa Bonita Panama
Outdoor pool, free cabanas, pool umbrellas
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
9.6 out of 10, Exceptional, (471)
"Na"
The price is $220
$242 total
includes taxes & fees
Jun 15 - Jun 16
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Couples treatment rooms, steam room, Turkish bath, body treatments
Bristol Panama, a Registry Collection Hotel
5.0 star property
9.2 out of 10, Wonderful, (1000)
"The best parts were cleanliness, and one of the best restaurants he 5th floor. The food was outstanding. "
The price is $199
$219 total
includes taxes & fees
May 25 - May 26
Bristol Panama, a Registry Collection Hotel
Porch
Villa Palma Boutique Hotel
5.0 star property
9.4 out of 10, Exceptional, (276)
"An excellent choice when staying in old town, Panama City, Panama. The staff was exceedingly friendly, taking the time and effort to know you personally, as well as ready to offer advice and assistance. They genuinely wanted guests to enjoy their vacation. Perfect location near the bay, within walking distance of many fine restaurants and local plazas, it was the former home of one of Panama's Vice Presidents. The Villa Palma Boutique Hotel offered simple elegance and a warm atmosphere,...
Villa Palma Boutique Hotel

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in San Francisco.
Crowne Plaza Panama Airport, an IHG Hotel

Crowne Plaza Panama Airport, an IHG Hotel

Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
The price is $107 per night from Jun 2 to Jun 3
$107
$118 total
includes taxes & fees
Jun 2 - Jun 3
8.2/10 Very Good! (1,861 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 5-star hotels in San Francisco?
JW Marriott Panama is among the most popular picks around the Panama City neighborhood of San Francisco based on Expedia customer reviews. The Bahia Grand Hotel and Bristol Panama, a Registry Collection Hotel are other 5-star hotels in this area that rank highest with guests.
How much does it cost to stay in a 5-star hotel in San Francisco?
There are a variety of pricing options for 5-star hotels in San Francisco on Expedia. How much you’ll pay will depend on when you travel, length of stay and other factors. Compare all of the available accommodations for your chosen dates and use our pricing and other filters to score the ideal upscale stay.

  • Search for the lowest price per night from $87

What makes a hotel 5 stars in San Francisco?
Faultless guest service is the foundation of every 5-star hotel in San Francisco. From the minute you step through the door, staff ensure your every need is met, whether recommending activities or providing in-room massage treatments. Additionally, hotels have to feature upscale amenities to be considered for a 5-star rating. These can include luxury toiletries, saunas or spas, pools, gourmet kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in San Francisco?
Expedia’s filter tool is the easiest way to find exactly what you want. Check the “All inclusive” and “5-star” boxes to show the most luxurious hotels in San Francisco where your accommodations, meals, activities and entertainment are included in the upfront price. At these getaways, your vacation is pure relaxation and indulgence from the moment you arrive.
What are the top 5-star spa hotels in San Francisco?
Enjoy a wide range of spa treatments, therapies and amenities at Bristol Panama, a Registry Collection Hotel. Alternatively, prioritize your health and well-being and focus on self-care at The Bahia Grand Hotel or JW Marriott Panama. These premium 5-star spa properties are located in or near San Francisco.
Are there any 5-star vacation rentals in San Francisco?
Although there aren’t any 5-star vacation rentals in San Francisco on our site, we have a range of escapes that promise a fabulous getaway. Find one that matches your needs by checking out our vacation rentals in San Francisco.

Recent reviews of San Francisco hotels
Expedia verified reviews

JW Marriott Panama

JW Marriott Panama

5/5 Excellent
"Nice place to stay in Panama"
A verified traveler stayed at JW Marriott Panama
Posted 1 day ago
JW Marriott Panama