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Find 5 Star Hotels in Uptown, OH from $124

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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Uptown.
Hilton Cincinnati Netherland Plaza

Hilton Cincinnati Netherland Plaza

35 W 5th St Cincinnati OH
$104 nightly
$124 total
Sep 27 - Sep 28
Total with taxes and fees
8/10 Very Good! (1,734 reviews)
Hilton Cincinnati Netherland Plaza
21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati

609 Walnut St Cincinnati OH
$156 nightly
$187 total
Sep 27 - Sep 28
Total with taxes and fees
21c Museum Hotel Cincinnati
The Westin Cincinnati

The Westin Cincinnati

21 E 5th St Cincinnati OH
$174 nightly
$207 total
Sep 27 - Sep 28
Total with taxes and fees
The Westin Cincinnati
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Uptown

A zoo, a college vibe, and sights from Cincinnati Zoo and Botanical Garden to Fifth Third Arena—discover it all in Uptown.

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The entrance to the Cincinnati Zoo & Botanical Garden with a sign above the gate and a flower bed in the foreground.

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Uptown Five Star Hotel Information

If you’re searching for the celebrity treatment, the 5 star hotels in Uptown are your dreams come true. From sprawling resorts to fancy hot spots, theseUptown 5 star hotels immerse each traveler in the most elite experience money can buy. Want to unwind with a VIP-worthy spa treatment? These hotels have the leisure you're looking for.

Interested in sampling world-class cuisine? The on-site restaurants at the 5 stars hotels in Uptown, Cincinnati, let you do just that. You’ll even be able to book a room (or perhaps a penthouse?) at first-rate hotels near the region’s can’t-miss sights and most bustling shopping centers. Plus, many globe-trotters who visit Uptown five star hotels find incredible rates and deep discounts thanks to Expedia, so you can score a deal without sacrificing an ounce of quality.

Everything you could possibly want (and a few things you didn’t know you needed): That’s what you’ll receive when you stay at Uptown 5 star hotels.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Uptown?
The amount you pay for a 5-star hotel in Uptown depends on things such as when you plan to go and the length of your trip. An insider tip for landing the best deal? Use our pricing filters to compare all of the available accommodations for your chosen dates.
  • Search for the lowest price per night from $124
What makes a hotel 5 stars in Uptown?
From high-end dining venues and 24/7 fitness centers to pools and premium bedding, the 5-star experience in Uptown is all about luxury and comfort. But it takes more than just upscale perks to get a 5-star rating. Stays must also deliver extraordinary guest-focused services like beauty treatments, laundry and dry cleaning and 24-hour concierge services.
Are there any 5-star all-inclusive resorts in Uptown?
Find an indulgent stay that includes your lodging, meals, drinks and entertainment in Uptown with Expedia's filters. Search for properties with a 5-star rating and click on the "All inclusive" filter. Make sure you check what's included in the purchase price. That way, you'll be ready to maximize the premium perks on offer from the moment you step into the lobby.

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