Mississippi may have travel restrictions in place due to COVID-19.

Find out moreOpens in new tab or window

Find Non-Smoking Hotels in Biloxi, MS from $69

Search over 1 million properties and 550 airlines worldwide

Members save 10% more on select hotels, cars, activities and vacation rentals. Sign up.

Free cancellation on most hotels. Because flexibility matters.

Top Biloxi Non-Smoking Hotels

Palace Casino Resort
4 out of 5
158 Howard Ave, Biloxi, MS
Free CancellationReserve now, pay when you stay
The price is $69 per night from Sep 27 to Sep 28
4.5/5Wonderful! (2,460 reviews)

"Everything was excellent, we enjoyed our stay and will definitely go back."…"

Reviewed on Sep 22, 2020

Palace Casino Resort
Beach Life 101. How Vacationing is Done!
5/5Exceptional! (14 reviews)
Loved this property!

"The property was exactly as shown in the pictures. It was nicely decorated and had all the amenities you would want. The pool was right outside the door and the beach was across the street. I would definitely stay there again!"…"

Reviewed on Jul 6, 2020

Beach Life 101. How Vacationing is Done!
New Home, 7 Min. Walk to the Beach, and No Stairs to Climb!
5/5Exceptional! (46 reviews)
Great house

"The house is great. Our third visit and Our favorite place to stay in the area. We’ll be back."…"

Reviewed on Sep 4, 2020

New Home, 7 Min. Walk to the Beach, and No Stairs to Climb!

You could be seeing lower prices

With member prices, you could save 10% or more right now on thousands of properties.
Amazing Water Front House in Golf Course Community. ???
4.9/5Exceptional! (31 reviews)
Beautiful and perfect location

"The house was absolutely beautiful and was far beyond anything we expected. It was perfect for our get away. Quiet and quaint with everything we wanted to do close by. We brought our kayaks and couldn’t have asked for a better place to enjoy the gulf. It really is a an amazing place to enjoy yourself ..."…"

Reviewed on Aug 24, 2020

Amazing Water Front House in Golf Course Community. ???
Azalea Cottage - Ocean Springs Perfect Location! 3 Blocks to Beach & Downtown!!!
The price is $80 per night from Oct 1 to Oct 2
4.9/5Exceptional! (78 reviews)

"Loved it! Highly recommended. Everything was was clean and perfect."…"

Reviewed on Sep 14, 2020

Azalea Cottage - Ocean Springs Perfect Location! 3 Blocks to Beach & Downtown!!!
Bay Town Inn
2.5 out of 5
208 N Beach Blvd, Bay St Louis, MS
Free Cancellation
The price is $159 per night from Oct 4 to Oct 5
4.8/5Exceptional! (22 reviews)

"Amazing personal touches. Homemade Cookies, muffins, handwritten note. Very clean Heart of a lovely home experience not a cold impersonal, Hotel atmosphere. Will certainly return."…"

Reviewed on Dec 20, 2019

Bay Town Inn
?blue Beach House - Swimming Pool, Casinos, Gated Complex Newly Renovated
4.8/5Exceptional! (46 reviews)
Great beach rental

"Stayed here over Labor Day weekend. It was the perfect getaway for our large family. Check in was easy. And the townhouse had everything we needed. Would definitely stay here again."…"

Reviewed on Sep 8, 2020

?blue Beach House - Swimming Pool, Casinos, Gated Complex Newly Renovated
100 Reasons TO GO TO THE Beach!
4.8/5Exceptional! (13 reviews)
Beautiful Condo

"Conveniently located and a quick walk to the beach. Everything was so nice and comfortable. I would definitely stay again."…"

Reviewed on Aug 31, 2020

100 Reasons TO GO TO THE Beach!
? Beach House - Swimming Pool, Casinos, Gated Complex Newly Renovated
4.8/5Exceptional! (40 reviews)
Great for a family!

"We loved having 3 bathrooms ... a game changer! The train is loud when it comes by. And the pool is right next door, which is convenient but can be loud, too. Put a sound machine app on your phone for sure. The host was a great communicator. We drove to the beach every day, and there is a really ..."…"

Reviewed on Aug 5, 2020

? Beach House - Swimming Pool, Casinos, Gated Complex Newly Renovated
Carroll House Cottages
3 out of 5
304 Carroll Avenue, Bay St Louis, MS
The price is $150 per night from Oct 1 to Oct 2
4.7/5Exceptional! (71 reviews)

"Had a fun weekend!"…"

Reviewed on Feb 12, 2020

Carroll House Cottages
Beau Rivage
4 out of 5
875 Beach Blvd, Biloxi, MS
The price is $89 per night from Sep 28 to Sep 29
4.5/5Wonderful! (1,972 reviews)

"Room was nice and check in lady was really nice and considerate"…"

Reviewed on Sep 3, 2020

Beau Rivage
South Beach Biloxi Hotel & Suites
3.5 out of 5
1735 Beach Blvd., Biloxi, MS
Free CancellationReserve now, pay when you stay
The price is $129 per night from Oct 20 to Oct 21
4.3/5Excellent! (985 reviews)

"I love the boardwalk & balcony. Very clean hotel and friendly staff"…"

Reviewed on Aug 31, 2020

South Beach Biloxi Hotel & Suites
Hard Rock Hotel Casino Biloxi
777 Beach Blvd., Biloxi, MS
Get Rates
4.3/5Excellent! (388 reviews)
Nice

"Nice , convenient , clean , come on , I don't want to Write book"…"

Reviewed on May 1, 2017

Hard Rock Hotel Casino Biloxi
Margaritaville Resort Biloxi
3.5 out of 5
195 Beach Blvd, Biloxi, MS
Free CancellationReserve now, pay when you stay
The price is $113 per night from Sep 27 to Sep 28
4.2/5Very Good! (3,404 reviews)

"I loved the view of the water from the balcony. The customer service was great. Parking was convenient."…"

Reviewed on Sep 23, 2020

Margaritaville Resort Biloxi
IP Casino Resort Spa-Biloxi
4 out of 5
850 Bayview Ave, Biloxi, MS
Free CancellationReserve now, pay when you stay
The price is $76 per night from Oct 1 to Oct 2
4.1/5Very Good! (3,266 reviews)

"Stayed here for the cheap deals at the time. Going in did not expect much but In the end I was very pleased with the property and room. The casino was great and the food from the restaurant downstairs was fantastic. I really enjoyed my stay here would recommend it 8/10!"…"

Reviewed on Sep 9, 2020

IP Casino Resort Spa-Biloxi
Country Inn & Suites by Radisson, Biloxi-Ocean Springs, MS
2.5 out of 5
13900 Wilfred Seymour Rd, Ocean Springs, MS
Free CancellationReserve now, pay when you stay
The price is $76 per night from Sep 27 to Sep 28
4.1/5Very Good! (966 reviews)

"I like it that the room I booked was not available"…"

Reviewed on Sep 11, 2020

Country Inn & Suites by Radisson, Biloxi-Ocean Springs, MS
Best Western Plus Cypress Creek
2.5 out of 5
7921 Lamar Pool, Biloxi, MS
Free CancellationReserve now, pay when you stay
The price is $76 per night from Oct 1 to Oct 2
4/5Very Good! (992 reviews)

"The warm breakfast promised was a brown paper lunch bag with an apple, bottled water, and mini muffin."…"

Reviewed on Aug 17, 2020

Best Western Plus Cypress Creek
Regency Inn & Suites Biloxi
2 out of 5
11969 Bobby Eleuterus Blvd, D'Iberville, MS
Free CancellationReserve now, pay when you stay
The price is $74 per night from Sep 27 to Sep 28
3.9/5Good! (960 reviews)
So So

"It was fine until people arrived at 1:30am making to much noise next door"…"

Reviewed on Mar 19, 2020

Regency Inn & Suites Biloxi
Don't see what you're looking for?
We've got more Non-Smoking Hotels. Find the right one for you.
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Pocket Guide: Non-Smoking Hotels in Biloxi

Search for hotels in Biloxi on Expedia. You can easily find your hotels in Biloxi using one of the methods below:

  • View our selection of featured hotels in Biloxi
  • Use the map to find hotels in the Biloxi neighborhood you prefer
  • Use the filters to see hotels in a specific area of Biloxi, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Biloxi
  • Enter your travel dates to view the best deals on hotels in Biloxi - while they last

More trip options