---
title: "20 Best B&B in Mayesville, SC - Bed and Breakfast from $139 | Expedia"
description: "Travel the World Better - with a Bed and Breakfast in Mayesville! Read reviews, search by map, and rent your dream B&B in Mayesville with Expedia."
canonical: "https://www.expedia.com/Mayesville-Bed-And-Breakfast.d3000456025-aaBedAndBreakfast.Travel-Guide-Accommodation"
language: en-US
market: US
currency: USD
prices_as_of: 2026-11-15T07:16:54Z
---

Plan your trip

- [Mayesville Travel Guide](https://www.expedia.com/Mayesville.dx3000456025)
- [Hotels in Mayesville](https://www.expedia.com/Mayesville-Hotels.d3000456025.Travel-Guide-Hotels)
- [Flights to Mayesville](https://www.expedia.com/Cheap-Flights-To-Mayesville.d3000456025.Travel-Guide-Flights)
- [Car Rentals in Mayesville](https://www.expedia.com/Car-Rentals-In-Mayesville.d3000456025.Car-Rental-Guide)
- [Mayesville Vacation Packages](https://www.expedia.com/Mayesville.d3000456025.Destination-Travel-Guides)
- [Vacation Rentals in Mayesville](https://www.expedia.com/Mayesville-Vacation-Rentals.d3000456025.Travel-Guide-VacationRentals)

![A sunflower in a field with a dirt path and trees in the background.](https://images.trvl-media.com/place/3000456025/6a3c56a6-b58b-4522-a79c-15e608af44bf.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Caroline Nunez

# Book Mayesville Bed & Breakfast

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### Upfront pricing
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## Check prices for these dates

[Check prices for these dates, December 15 – 16, 2026](https://www.expedia.com/Hotel-Search?regionId=3000456025&startDate=2026-12-15&endDate=2026-12-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&lodging=BED%5FAND%5FBREAKFAST)

[View in a map](https://www.expedia.com/Hotel-Search?regionId=3000456025&stayLength=1&daysInFuture=30&pwaOverlay=map)

## Our top choices for Mayesville bed & breakfast

### [1\. 1912 Bed and Breakfast](https://www.expedia.com/Sumter-Hotels-1912-Bed-And-Breakfast.h26733717.Hotel-Information)

![A two-story house with a wrap-around porch, brick exterior, and a front entrance with steps.](https://images.trvl-media.com/lodging/27000000/26740000/26733800/26733717/aa63167f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

- Location: Sumter
- Guest rating: 10/10 (Exceptional, 336 reviews)
- Price: $139 nightly, $139 total, Nov 19 - Nov 20, Total with taxes and fees, for Our top choices for Mayesville bed &amp; breakfast
- Review: Very friendly, I’d stay again, by Heather

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://www.expedia.com/Hotel-Search?startDate=2026-11-29&endDate=2026-11-30&regionId=3000456025&adults=2&lodging=BED%5FAND%5FBREAKFAST&sort=RECOMMENDED&openPlayBack=true)

## Learn more about Mayesville

Venture to Crystal Lakes Golf Course and Sumter Mall—just two of the sights around Mayesville.

[See all hotels in Mayesville](https://www.expedia.com/Hotel-Search?startDate=2026-11-29&endDate=2026-11-30&adults=2&regionId=3000456025)

![A sunflower in a field with a dirt path and trees in the background.](https://images.trvl-media.com/place/3000456025/6a3c56a6-b58b-4522-a79c-15e608af44bf.jpg?impolicy=fcrop&w=899&h=675&p=1&q=high)

Photo by Caroline Nunez

## Frequently Asked Questions

### What is the nightly rate for a Bed and Breakfast in Mayesville?

Prices for B&Bs in Mayesville often vary, but you can find a great deal from $139 with Expedia. All sorts of factors affect price, such as location and the time of year. It usually costs more to stay at Mayesville B&Bs over the weekend too. Travelers can find the best deals by being flexible with their dates, and by using our filters to sort prices from low to high.

### What is the difference between a Mayesville Bed & Breakfast and a hotel?

Every Mayesville B&B has its own unique feel. Whether it’s a cozy reading space or a sunlit breakfast nook to enjoy your morning cup of coffee, the quaint details are what make bed and breakfasts a home away from home. Travelers can look forward to personal touches, thoughtful amenities and of course a scrumptious breakfast at Mayesville B&Bs.

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