A boat tour on a canal with a bridge in the background.

Downtown San Antonio Vacations from $452

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Downtown San Antonio Vacation

Lock in a vacation package to Downtown San Antonio and experience everything this riverside neighborhood has to offer. Noted for its shopping, walking and dining, your next great adventure can be found right here. When it's time to explore the sights, you'll find lots of top attractions nearby including Alamo, Alamodome and Shops at Rivercenter. Tick off one or all during your trip to Downtown San Antonio. Expedia can help you turn your ideal Downtown San Antonio vacation into reality, whatever your budget or travel plans.

The Latest Downtown San Antonio Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Feb 5 - Feb 8

    Hilton Garden Inn San Antonio Airport South + Flight

    Uptown Central
    3 nights
    3.0 star property
    8.4/10 - Very good (1,001 reviews)
    "Great stay!"
    Reviewed November 11, 2026
    Roundtrip • Boston (BOS) - San Antonio (SAT)
    BOS - SAT • 1 stop SAT - BOS • 1 stop
    $532
    $452
    per traveler
    found 16 hours ago
    Hilton Garden Inn San Antonio Airport South
  • Feb 5 - Feb 8

    Hyatt Regency Hill Country Resort and Villas + Flight

    Far West Side
    3 nights
    4.0 star property
    8.8/10 - Excellent (1,000 reviews)
    "It’s alright - expensive for what your money buys"
    Reviewed November 4, 2026
    Roundtrip • Boston (BOS) - San Antonio (SAT)
    BOS - SAT • 1 stop SAT - BOS • 1 stop
    $1,132
    $859
    per traveler
    found 16 hours ago
    Hyatt Regency Hill Country Resort and Villas
  • Feb 5 - Feb 8

    Mokara Hotel & Spa San Antonio + Flight

    Downtown San Antonio
    3 nights
    4.5 star property
    9.6/10 - Exceptional (1,002 reviews)
    Roundtrip • Boston (BOS) - San Antonio (SAT)
    BOS - SAT • 1 stop SAT - BOS • 1 stop
    $1,000
    $824
    per traveler
    found 16 hours ago
    Mokara Hotel & Spa San Antonio
  • Feb 5 - Feb 8

    Hotel Contessa + Flight

    Downtown San Antonio
    3 nights
    4.0 star property
    9.0/10 - Wonderful (4,060 reviews)
    Roundtrip • Boston (BOS) - San Antonio (SAT)
    BOS - SAT • 1 stop SAT - BOS • 1 stop
    $767
    $645
    per traveler
    found 16 hours ago
    Hotel Contessa
  • Feb 5 - Feb 7

    Sítio El Tropicano + Flight

    Downtown San Antonio
    2 nights
    4.5 star property
    Roundtrip • Boston (BOS) - San Antonio (SAT)
    BOS - SAT • Nonstop SAT - BOS • Nonstop
    $753
    $635
    per traveler
    found 23 hours ago
    Sítio El Tropicano

Where to stay in Downtown San Antonio

Find the best Downtown San Antonio areas and neighborhoods for the activities you enjoy most. Learn more about Downtown San Antonio
Learn more about Downtown San Antonio

Uptown Central

While visiting Uptown Central, you might make a stop by sights like Marion Koogler McNay Art Museum and Alamo Quarry Market.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Medical Center District

While Medical Center District isn't home to many top sights, Wonderland of the Americas Mall and Huebner Oaks are some notable places to visit nearby.

Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Crystal Ice Palace.

Stone Oak

Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.

Discover the most popular places to visit in Downtown San Antonio

What to do near Downtown San Antonio

Downtown San Antonio Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.