Title: Isla Caja de Muertos Vacation Packages 2026 from $522 | Expedia.com

[Isla Caja de Muertos Travel Guide](https://expedia.com/Isla-Caja-De-Muertos.dx6360657)[Hotels in Isla Caja de Muertos](https://expedia.com/Isla-Caja-De-Muertos-Hotels.d6360657.Travel-Guide-Hotels)[Vacation Rentals in Isla Caja de Muertos](https://expedia.com/Isla-Caja-De-Muertos-Vacation-Rentals.d6360657.Travel-Guide-VacationRentals)[Flights to Isla Caja de Muertos](https://expedia.com/Cheap-Flights-To-Isla-Caja-De-Muertos.d6360657.Travel-Guide-Flights)[Car Rentals in Isla Caja de Muertos](https://expedia.com/Car-Rentals-In-Isla-Caja-De-Muertos.d6360657.Car-Rental-Guide)

![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=300&q=medium)

# Isla Caja de Muertos Vacations from $522

## Book a Hotel + Flight or Car together to unlock savings

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## The Latest Isla Caja de Muertos vacation packages

Price found within the past 48 hours. Click for updated prices.

![La Calma Poshtel](https://images.trvl-media.com/lodging/92000000/91850000/91842300/91842215/f0b6eaf0_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### La Calma Poshtel

Santurce

$522

per person

May 8 - May 15

found 1 day ago

Roundtrip flight included

Boston (BOS) to San Juan (SJU)

7.2/10 Good! (700 reviews)

Every thing was great I would definitely stay again

Reviewed on Mar 29, 2026

![Hotel Puerto Valdes](https://images.trvl-media.com/lodging/70000000/69380000/69371400/69371387/95ad4f15_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel Puerto Valdes

San Juan Antiguo

Save 100% on your flight

$706

per person

Jun 18 - Jun 22

found 2 days ago

Roundtrip flight included

Boston (BOS) to San Juan (SJU)

8.8/10 Excellent! (594 reviews)

Hotel is very clean and Hector very friendly and helpful.thank you

Reviewed on Mar 28, 2026

![Ola Boutique Hotel](https://images.trvl-media.com/lodging/105000000/104220000/104217200/104217135/7963308f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Ola Boutique Hotel

Condado

Save 100% on your flight

$865

per person

Jun 18 - Jun 22

found 2 days ago

Roundtrip flight included

Boston (BOS) to San Juan (SJU)

9/10 Wonderful! (741 reviews)

Breakfast was good and fresh

Reviewed on Mar 27, 2026

![Aire de O:live](https://images.trvl-media.com/lodging/1000000/530000/527600/527599/8d4c39ed_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Aire de O:live

Isla Verde

Save 100% on your flight

$861

per person

Jun 18 - Jun 22

found 2 days ago

Roundtrip flight included

Boston (BOS) to San Juan (SJU)

9.2/10 Wonderful! (469 reviews)

Great beach place. Walk right out to beach. Waited service on beach. Staff opens the door for you. Foods good. What else do you need?…

Reviewed on Mar 22, 2026

![Lazy Parrot Inn](https://images.trvl-media.com/lodging/1000000/910000/900400/900306/d84e57b2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Lazy Parrot Inn

$700

per person

Jun 23 - Jun 28

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to San Juan (SJU)

9.2/10 Wonderful! (1,007 reviews)

Beautiful, quiet and comfortable! Gabriella and her staff are among the finest I’ve ever come across. Will be back!

Reviewed on Mar 30, 2026

Don't see what you're looking for?

See all available trips from Columbus to Isla Caja de Muertos

[View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-30/2026-05-07/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=SJU&NumRoom=1&NumAdult=2&NumChild=0&paandie=true)

### Discover the most popular places to visit in Isla Caja de Muertos

![La Guancha](https://images.trvl-media.com/place/6081945/06459c47-098b-4975-a3dc-4e0918d2a0a5.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### La Guancha

Take a stroll down Ponce’s waterfront boardwalk and experience its lively dining scene, local music, playgrounds, boat rides and views out to Isla Caja de Muertos.

[](https://expedia.com/La-Guancha-Ponce.d6081945.Vacation-Attraction)

![Parque de Bombas](https://images.trvl-media.com/place/6081925/8376ab9b-c23c-449c-a01b-7897d11ab068.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Parque de Bombas

This small, wooden fire station in the heart of Ponce is a historical and architectural monument.

[](https://expedia.com/Parque-De-Bombas-Ponce-Centro.d6081925.Vacation-Attraction)

![El Museo Castillo Serralles](https://images.trvl-media.com/place/6081931/3a62586e-5a9d-4cc8-8557-1cb4103e3cf2.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### El Museo Castillo Serralles

Discover an empire built on sugar and rum as you explore the intriguing galleries and luxurious refurbished rooms in this 1930s Spanish Revival mansion.

[](https://expedia.com/El-Museo-Castillo-Serralles-Ponce.d6081931.Vacation-Attraction)

### What to do in Isla Caja de Muertos

![Mystic Waters A Bioluminescent Night Tour](https://mediaim.expedia.com/localexpert/50872055/8433175a-10ff-4c58-bd8a-c56dafbf0231.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Mystic Waters A Bioluminescent Night Tour

$65

per adult

**100%** of travellers recommend

[](https://expedia.com/things-to-do/mystic-waters-a-bioluminescent-night-tour.a50872055.activity-details)

![Half-Day Center of Puerto Rico Cultural Tour](https://mediaim.expedia.com/localexpert/1133049/5e330c79-a5ad-4f71-a6b7-1c0c3d5d2a72.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Half-Day Center of Puerto Rico Cultural Tour

$80

per adult

**100%** of travellers recommend

[](https://expedia.com/things-to-do/half-day-center-of-puerto-rico-cultural-tour.a1133049.activity-details)

![Utuado Canyon, River & Waterfall Adventure in Puerto Rico](https://mediaim.expedia.com/localexpert/2666681/7427190c-5d48-43cc-8d04-d599e05b2354.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Utuado Canyon, River & Waterfall Adventure in Puerto Rico

$165

per adult

[](https://expedia.com/things-to-do/utuado-canyon.a2666681.activity-details)

[See all activities in Isla Caja de Muertos](https://expedia.com/things-to-do/search?rid=6360657)

## Isla Caja de Muertos Hotel Deals

![Hilton Ponce Golf & Casino Resort](https://images.trvl-media.com/lodging/1000000/10000/6400/6322/46c68573_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hilton Ponce Golf & Casino Resort

1150 Caribe Avenue Ponce 

$202 nightly

$224 total

Apr 5 - Apr 6

Total with taxes and fees

8.8/10 Excellent! (1,005 reviews)

Great

Reviewed on Mar 26, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=6322&PinnedHotelID=6322&HadPinnedHotel=true&regionId=6360657)

![Aloft Ponce Hotel & Casino](https://images.trvl-media.com/lodging/58000000/57920000/57918000/57917934/8c7e7d6c_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Aloft Ponce Hotel & Casino

Street No 2 KM 228.9 Ponce 

$179 nightly

$199 total

Apr 1 - Apr 2

Total with taxes and fees

8.8/10 Excellent! (1,164 reviews)

Great stay!!

Reviewed on Mar 30, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F1%2F2026&endDate=4%2F2%2F2026&selected=57917934&PinnedHotelID=57917934&HadPinnedHotel=true&regionId=6360657)

![Ponce Plaza Hotel & Casino](https://images.trvl-media.com/lodging/3000000/2840000/2836400/2836309/fabf48f6_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Ponce Plaza Hotel & Casino

Reina Street Ponce 

Fully refundableReserve now, pay when you stay

$175 nightly

$192 total

Apr 5 - Apr 6

Total with taxes and fees

9.2/10 Wonderful! (1,009 reviews)

Room by the street. Very loud music from passing cars at all hours of the night.

Reviewed on Mar 30, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=2836309&PinnedHotelID=2836309&HadPinnedHotel=true&regionId=6360657)

[See all 239 properties in Isla Caja de Muertos](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=4%2F1%2F2026&endDate=4%2F2%2F2026&regionId=6360657)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Find the Best Isla Caja de Muertos Vacation Packages

## Isla Caja de Muertos Essential Information

| Language        | Spanish                              |
| --------------- | ------------------------------------ |
| Currency        | U.S dollars                          |
| Local Welcome   | ¡Hola!                               |
| Local Goodbye   | Adiós                                |
| Closest Airport | Luis Munoz Marin Intl. Airport (SJU) |

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- [Jetblue Airways Orlando (MCO) to Ponce (PSE) flights ](https://www.expedia.com/lp/flight-routes/jetblue-airways-from-orlando-intl-to-mercedita/b6/mco/pse)
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- [Flights from Pittsburgh (PIT) to Ponce (PSE) ](https://www.expedia.com/lp/flights/pit/pse/pittsburgh-to-ponce)
- [Flights from Kansas City (MCI) to Ponce (PSE) ](https://www.expedia.com/lp/flights/mci/pse/kansas-city-to-ponce)
- [Flights from West Palm Beach (PBI) to Ponce (PSE) ](https://www.expedia.com/lp/flights/pbi/pse/west-palm-beach-to-ponce)
- [Flights from Harrisburg (MDT) to Ponce (PSE) ](https://www.expedia.com/lp/flights/mdt/pse/harrisburg-to-ponce)
- [Flights from Allentown (ABE) to Ponce (PSE) ](https://www.expedia.com/lp/flights/abe/pse/allentown-to-ponce)
- [Flights from Washington (IAD) to Ponce (PSE) ](https://www.expedia.com/lp/flights/iad/pse/washington-to-ponce)
- [Flights from New York (NYC) to Ponce (PSE) ](https://www.expedia.com/lp/flights/nyc/pse/new-york-to-ponce)
- [Flights from St. Louis (STL) to Ponce (PSE) ](https://www.expedia.com/lp/flights/stl/pse/st-louis-to-ponce)
- [Flights from Richmond (RIC) to Ponce (PSE) ](https://www.expedia.com/lp/flights/ric/pse/richmond-to-ponce)
- [Flights from Salt Lake City (SLC) to Ponce (PSE) ](https://www.expedia.com/lp/flights/slc/pse/salt-lake-city-to-ponce)
- [Flights from Cincinnati (CVG) to Ponce (PSE) ](https://www.expedia.com/lp/flights/cvg/pse/cincinnati-to-ponce)
- [Flights from Las Vegas (LAS) to Ponce (PSE) ](https://www.expedia.com/lp/flights/las/pse/las-vegas-to-ponce)
- [Flights from Memphis (MEM) to Ponce (PSE) ](https://www.expedia.com/lp/flights/mem/pse/memphis-to-ponce)
- [Flights from New Haven (HVN) to Ponce (PSE) ](https://www.expedia.com/lp/flights/hvn/pse/new-haven-to-ponce)
- [Flights from Trenton (TTN) to Ponce (PSE) ](https://www.expedia.com/lp/flights/ttn/pse/trenton-to-ponce)
- [Flights from Charleston (CHS) to Ponce (PSE) ](https://www.expedia.com/lp/flights/chs/pse/charleston-to-ponce)
- [Flights from Santo Domingo (SDQ) to Ponce (PSE) ](https://www.expedia.com/lp/flights/sdq/pse/santo-domingo-to-ponce)
- [Flights from Savannah (SAV) to Ponce (PSE) ](https://www.expedia.com/lp/flights/sav/pse/savannah-to-ponce)
- [Flights from El Paso (ELP) to Ponce (PSE) ](https://www.expedia.com/lp/flights/elp/pse/el-paso-to-ponce)
- [Flights from Pensacola (PNS) to Ponce (PSE) ](https://www.expedia.com/lp/flights/pns/pse/pensacola-to-ponce)
- [Flights from Louisville (SDF) to Ponce (PSE) ](https://www.expedia.com/lp/flights/sdf/pse/louisville-to-ponce)
- [Flights from Mayagüez (MAZ) to Ponce (PSE) ](https://www.expedia.com/lp/flights/maz/pse/mayaguez-to-ponce)
- [Flights from Knoxville (TYS) to Ponce (PSE) ](https://www.expedia.com/lp/flights/tys/pse/knoxville-to-ponce)
- [Flights from Omaha (OMA) to Ponce (PSE) ](https://www.expedia.com/lp/flights/oma/pse/omaha-to-ponce)
- [Flights from Fajardo (FAJ) to Ponce (PSE) ](https://www.expedia.com/lp/flights/faj/pse/fajardo-to-ponce)
- [Flights from Chicago (MDW) to Ponce (PSE) ](https://www.expedia.com/lp/flights/mdw/pse/chicago-to-ponce)
- [Flights from Greenville (GSP) to Ponce (PSE) ](https://www.expedia.com/lp/flights/gsp/pse/greenville-to-ponce)
- [Flights from Oklahoma City (OKC) to Ponce (PSE) ](https://www.expedia.com/lp/flights/okc/pse/oklahoma-city-to-ponce)
- [Flights from Islip (ISP) to Ponce (PSE) ](https://www.expedia.com/lp/flights/isp/pse/islip-to-ponce)
- [Flights from Sacramento (SMF) to Ponce (PSE) ](https://www.expedia.com/lp/flights/smf/pse/sacramento-to-ponce)
- [Flights from Sarasota (SRQ) to Ponce (PSE) ](https://www.expedia.com/lp/flights/srq/pse/sarasota-to-ponce)
- [Flights from Greensboro (GSO) to Ponce (PSE) ](https://www.expedia.com/lp/flights/gso/pse/greensboro-to-ponce)
- [Flights from Des Moines (DSM) to Ponce (PSE) ](https://www.expedia.com/lp/flights/dsm/pse/des-moines-to-ponce)
- [Flights from Grand Rapids (GRR) to Ponce (PSE) ](https://www.expedia.com/lp/flights/grr/pse/grand-rapids-to-ponce)
- [Flights from White Plains (HPN) to Ponce (PSE) ](https://www.expedia.com/lp/flights/hpn/pse/white-plains-to-ponce)

- [Puerto Rico Island Vacations ](https://www.expedia.com/Puerto-Rico-Island.d180021.Destination-Travel-Guides)
- [La Guancha ](https://www.expedia.com/La-Guancha-Ponce.d6081945.Vacation-Attraction)
- [Playa Vacations ](https://www.expedia.com/Playa.d553248635976173760.Destination-Travel-Guides)
- [Santa Isabel Vacations ](https://www.expedia.com/Santa-Isabel.d6035096.Destination-Travel-Guides)

- [Car rentals near La Guancha ](https://www.expedia.com/Car-Rentals-In-La-Guancha.d6081945.Car-Rental-Guide)
- [Car rental Ponce Airport (PSE) ](https://www.expedia.com/Car-Rentals-In-Mercedita.d6031272.Car-Rental-Guide)
- [Thrifty Car Rental Rental Cars in Mercedita ](https://www.expedia.com/Thrifty-Car-Rental-Car-Rentals-In-Mercedita.d6031272-c45.Car-Rental-Guide-Suppliers)
- [Hertz Rental Cars in Mercedita ](https://www.expedia.com/Hertz-Car-Rentals-In-Mercedita.d6031272-c40.Car-Rental-Guide-Suppliers)
- [Avis Rental Cars in Mercedita ](https://www.expedia.com/Avis-Car-Rentals-In-Mercedita.d6031272-c41.Car-Rental-Guide-Suppliers)
- [Budget Rental Cars in Mercedita ](https://www.expedia.com/Budget-Car-Rentals-In-Mercedita.d6031272-c39.Car-Rental-Guide-Suppliers)
- [Alamo Rent A Car Rental Cars in Mercedita ](https://www.expedia.com/Alamo-Rent-A-Car-Car-Rentals-In-Mercedita.d6031272-c6.Car-Rental-Guide-Suppliers)
- [Minivan Car Rentals near Mercedita ](https://www.expedia.com/Minivan-Car-Rentals-In-Mercedita.d6031272-tMinivan.Car-Rental-Guide-Class)

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.

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