Photo by Eddie Melendez

Santa Isabel Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out
  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals
  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings
  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
In two months
In three months
In four months

Vacation Rentals in Santa Isabel

Seaside Serenity – Oceanfront Villa with Infinity Pool & Garden Sanctuary

Santa Isabel
10.0 out of 10, Exceptional, (1)
"Such an amazing place. Views are spectacular. The outside family area was our favorite part. The pool was perfect too. My family and I were very comfortable here. Definitely look forward to coming back!"
United States
Selena R.
Seaside Serenity – Oceanfront Villa with Infinity Pool & Garden Sanctuary

Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

Santa Isabel
10.0 out of 10, Exceptional, (1)
"Our stay at Mimi’s VRBO was unforgettable, and we’re already planning our return! After searching for the ideal family rental, we chose Mimi’s listing and it was a game-changer. Her warmth and quick responses made everything seamless. When our flight was delayed, Mimi arranged a car to get us to the property and coordinated a rental car delivery the next morning.The house is a gem in a safe, friendly neighborhood, steps from Walmart and close to dining options. Packed with kid-friendly amenities...
United States
Henry S.
$486 nightly
The price is $516
Nov 11 - Nov 12
Total with taxes and fees
Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Santa Isabel
8.8 out of 10, Excellent, (44)
"Everything was nice nice breeze"
United States
Maria S.
$332 nightly
The price is $353
Nov 16 - Nov 17
Total with taxes and fees
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Coming and enjoy panoramic views to mountains and sea in Santa Isabel

Santa Isabel
$320 nightly
The price is $340
Nov 16 - Nov 17
Total with taxes and fees
Coming and enjoy panoramic views to mountains and sea in Santa Isabel

La Gozadera Park

1.0 star property
Salinas
$126 nightly
The price is $137
Nov 11 - Nov 12
Total with taxes and fees
La Gozadera Park

The Place at the Sea

2.0 star property
Ponce
9.2 out of 10, Wonderful, (190)
"Great customer service and clean rooms. will stay there again if given the chance."
United States
CHRISTOPHER A
$75 nightly
The price is $82
Nov 19 - Nov 20
Total with taxes and fees
The Place at the Sea

Aibonito Hotel 210

2.5 star property
Aibonito
7.0 out of 10, Good, (14)
"El cuarto estaba limpio y como siempre facil aser el check in"
United States
Jose
$125 nightly
The price is $134
Nov 11 - Nov 12
Total with taxes and fees
Aibonito Hotel 210

Playa Apartments

2.5 star property
Salinas
7.6 out of 10, Good, (35)
"Waterfront view"
United States
Dana
$167 nightly
The price is $177
Nov 11 - Nov 12
Total with taxes and fees
Playa Apartments

Points Apartments

Guayama
10.0 out of 10, Exceptional, (2)
"Great property great people"
United States
Julian
$198 nightly
The price is $210
Nov 17 - Nov 18
Total with taxes and fees
Points Apartments

Cozy studio with private Pool and Bar modern amentities perfect for relaxation.

Cidra
10.0 out of 10, Exceptional, (3)
"We have a wonderful time! The pool and bar were perfect!"
United States
Anna D.
$240 nightly
The price is $254
Nov 11 - Nov 12
Total with taxes and fees
Cozy studio with private Pool and Bar modern amentities perfect for relaxation.

LA CASITA DEL LAGO

Cidra
10.0 out of 10, Exceptional, (2)
"Private, stunning view from the back porch, and the installations further down the hill (El Colmadito del Abuelo y La Casita del Abuelo) have amazing historical contents on the land and people. Glenda and Laura were incredible and the communication was easy. Would highly recommend for an intimate stay, one that permits exploration of the land and history, and one where you get a taste of the real deal Puerto Rico"
United States
Sonia R.
$179 nightly
The price is $190
Nov 11 - Nov 12
Total with taxes and fees
LA CASITA DEL LAGO

HW Tiny Home Cidra

Cidra
10.0 out of 10, Exceptional, (2)
"Beautiful area, great AC, clean hot tub, lovely acces to lake with paddleboat!"
United States
Elizabeth C.
$177 nightly
The price is $188
Nov 12 - Nov 13
Total with taxes and fees
HW Tiny Home Cidra

Grandpa's lake house lake private access mountain view museum 1950's experience

Cidra
9.4 out of 10, Exceptional, (6)
"The property is gorgeous amidst the beautiful mountains of Cidra. A true communion with nature. Topped by an excellent and accomodating host eager to impart her vast knowledge of culture and history of the region and making us feel most welcome! Thanks so much Laura!"
United States
Michael F.
$105 nightly
The price is $111
Nov 11 - Nov 12
Total with taxes and fees
Grandpa's lake house lake private access mountain view museum 1950's experience

Oasis Salinas

Salinas
7.8 out of 10, Good, (13)
"Excellent place to stay near everything in town "
United States
Mayra
$130 nightly
The price is $138
Nov 11 - Nov 12
Total with taxes and fees
Oasis Salinas

Cozy Apartment in town - City Dreams Guayama - Great Location

Guayama
8.6 out of 10, Excellent, (4)
"Everything was exactly as host had posted and the place was immaculate n cozy.the only problem would be the late nite drive bys w extra loud music but then again they do that everywhere inP.R. from our experience wen u stay in small towns I suppose LMFAO"
United States
Storm R.
$112 nightly
The price is $118
Nov 16 - Nov 17
Total with taxes and fees
Cozy Apartment in town - City Dreams Guayama - Great Location

Trinitarias Guest's House's pool/bar/karaoke/wifi

Salinas
10.0 out of 10, Exceptional, (2)
"Hecmar’s property was awesome!!! Near to restaurants, beaches etc..We felt comfortable at her home . I will definitely be back.."
United States
jackie r.
$160 nightly
The price is $170
Nov 18 - Nov 19
Total with taxes and fees
Trinitarias Guest's House's pool/bar/karaoke/wifi

Oasis in the South of the Island with Private Parking and Laundry. Pet friendly

Ponce
9.6 out of 10, Exceptional, (13)
"Nice updates and comfortable neighborhood, recommend Las Panas just down the street - great food! Second bedroom too small for 2-twin beds however."
United States
Kyle K.
$158 nightly
The price is $167
Nov 11 - Nov 12
Total with taxes and fees
Oasis in the South of the Island with Private Parking and Laundry. Pet friendly

Chandelier 301

3.0 star property
Ponce Centro
7.0 out of 10, Good, (8)
"Debido a que no hubo luz la nevera se desconjelo y se mojo todo el piso, tuvimos que secar con las toallas, sabemos que no es culpa del propietario.de todo lo demas fue exelwnte."
Mexico
Wilmarie
$150 nightly
The price is $161
Nov 11 - Nov 12
Total with taxes and fees
Chandelier 301

Nostra Casa Vagón

2.0 star property
Coamo
$126 nightly
The price is $132
Nov 11 - Nov 12
Total with taxes and fees
Nostra Casa Vagón

Cozy cabin with hot water jacuzzi and AC in the mountains of Guayama.

Guayama
10.0 out of 10, Exceptional, (2)
"Property was so beautiful didn’t have any complains. Everything you need in one spot you’d never want to leave."
United States
Jonathan
$177 nightly
The price is $188
Nov 11 - Nov 12
Total with taxes and fees
Cozy cabin with hot water jacuzzi and AC in the mountains of Guayama.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Isabel Hotel Reviews

Find out more about Santa Isabel

Everything you need to know about Santa Isabel vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Isabel vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Isabel vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Isabel vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Isabel. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Isabel in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $82 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Isabel rentals

At Expedia, we put the best Santa Isabel vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Isabel rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Isabel vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Isabel. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Santa Isabel?

Yes, there are vacation rentals close to the most popular attractions in Santa Isabel, or you can choose a secluded option if you're looking for relaxation. Santa Isabel is known for its shopping and restaurants. Make sure you have time to check out the beaches while you're in the area.

What's the top vacation rental that Santa Isabel has to offer?

Seaside Serenity – Oceanfront Villa with Infinity Pool & Garden Sanctuary: This highly rated vacation home rental in Santa Isabel is located by the ocean and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind. Other favorite homes for rent in Santa Isabel are Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL and Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep.

How many vacation rentals will I find in Santa Isabel?

Expedia has 7 vacation rentals for your stay in Santa Isabel.

What can I see and do in Santa Isabel?

Explore the area and family-friendly sights such as Museo de la Musica Puertorriquena, or get out into nature at a spot like Coamo Springs. Carribbean Cinemas Santa Isabel and Marina de Salinas are a couple of places you'll find in the larger area.

What are vacation rentals like in Santa Isabel?

Vacation rentals are privately owned properties you can reserve for a couple days or more in Santa Isabel. Vacation rentals offer extras like WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about cleanliness, vacation rentals can provide a sense of safety away from shared hotel elevators and busy lobbies while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a standard hotel, which makes a vacation rental a popular option for a family trip.