Title: Top Ayres Collection in La Mesa, CA - Expedia.com [La Mesa Travel Guide](https://expedia.com/La-Mesa.dx8484)[Hotels in La Mesa](https://expedia.com/La-Mesa-Hotels.d8484.Travel-Guide-Hotels)[Vacation Rentals in La Mesa](https://expedia.com/La-Mesa-Vacation-Rentals.d8484.Travel-Guide-VacationRentals)[Flights to La Mesa](https://expedia.com/Cheap-Flights-To-La-Mesa.d8484.Travel-Guide-Flights)[Things to do in La Mesa](https://expedia.com/Things-To-Do-In-La-Mesa.d8484.Travel-Guide-Activities)[Car Rentals in La Mesa](https://expedia.com/Car-Rentals-In-La-Mesa.d8484.Car-Rental-Guide)[La Mesa Vacation Packages](https://expedia.com/La-Mesa.d8484.Destination-Travel-Guides) ![View from Mount Helix, in La Mesa, near San Diego, California](https://images.trvl-media.com/place/8484/0fa3bc38-9bbb-4533-9232-a1a6e7720bc2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/8484/0fa3bc38-9bbb-4533-9232-a1a6e7720bc2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ## Check prices for these dates Tonight [Feb 22 - Feb 23](https://www.expedia.com/Hotel-Search?regionId=8484&startDate=2026-02-22&endDate=2026-02-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 23 - Feb 24](https://www.expedia.com/Hotel-Search?regionId=8484&startDate=2026-02-23&endDate=2026-02-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=8484&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=8484&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Hotels-Ayres-Collection.0-0-d8484--bAyresCollection.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Hotels-Ayres-Collection.0-0-d8484--bAyresCollection.Travel-Guide-Filter-Hotels) ## Top La Mesa Hotel Reviews ![Wyndham San Diego Bayside](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Lovely room, location, location, location, they have the best location. Staff was awesome." [](https://expedia.com/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![DoubleTree by Hilton San Diego - Del Mar](https://images.trvl-media.com/lodging/1000000/20000/15300/15236/5afe6cec_y.jpg) ### DoubleTree by Hilton San Diego - Del Mar 10/10 Excellent "Clean room and breakfast was okay. The water in the shower was not hot but I managed to adapt." [](https://expedia.com/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Del-Mar.h15236.Hotel-Information) ![Lafayette Hotel & Club](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/91a184a3_y.jpg) ### Lafayette Hotel & Club 10/10 Excellent "A totally unique and wonderful experience!" [](https://expedia.com/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) ![The Dana on Mission Bay](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "Great pool area by the bay and restaurant. " [](https://expedia.com/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![The DEXTRO Little Italy, BW Premier Collection](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/6fe441dd_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "Clean, nicely decorated and friendly staff" [](https://expedia.com/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Sheraton San Diego Resort](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "Your parking sucks 55 a night and we have to pay an additional 10\. To park across the street " [](https://expedia.com/San-Diego-Hotels-Sheraton-San-Diego-Resort.h11109.Hotel-Information) ![The Sofia Hotel](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84_y.jpg) ### The Sofia Hotel 10/10 Excellent "The hotel is hainte" [](https://expedia.com/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) ![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Very clean, staff was great, great value for the room and location " [](https://expedia.com/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![San Diego Mission Bay Resort](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/bbcdbd6d_y.jpg) ### San Diego Mission Bay Resort 10/10 Excellent "Yes room was clean, service was superb; we will stay here again for certain..!" 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