Mayo River Vacations from $535
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The Latest Mayo River vacation packages
Price found within the past 48 hours. Click for updated prices.
O.Henry Hotel
$768
per person
Nov 8 - Nov 11
found 4 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Greensboro (GSO)
9.8/10 Exceptional! (854 reviews)
Beautifully appointed hotel in keeping with the fine tradition of Southern hospitality. Every staff member we encountered was gracious, friendly and helpful. Our king room was spacious and inviting. Even the bathroom was sublime. The hotel bar was buzzing with good cheer on a Friday night. Our evening dinner and service at the on-site Green Valley Grill were excellent. Thanks goes to those who resurrected this newer O.Henry in the spirit and style of the original 1919 downtown landmark. Highly recommend.
Reviewed on Sep 22, 2026
Stay near popular Mayo River attractions
Reynolds Homestead
You can study the exhibits at Reynolds Homestead, a museum with a story of its own, during your travels to Patrick Springs. Amble around the area's forest or visit its spas.
Mayo River Hotel Deals
The Lodge at Primland, Auberge Collection
2000 Busted Rock Rd Meadows Of Dan VA
$1,394 nightly
$1,565 total
Oct 11 - Oct 12
Total with taxes and fees
9/10 Wonderful! (34 reviews)
"Expedia y la propiedad no aclararon los cargos y tuve que esperar casi 1 hora a que acreditaron el total del dinero que ya había pagado por adelantado. Reserven directamente"
Reviewed on Aug 28, 2026
Comfort Inn Martinsville
378 Commonwealth Blvd W Martinsville VA
Fully refundable
$100 nightly
$112 total
Oct 18 - Oct 19
Total with taxes and fees
6.8/10 (697 reviews)
"Poorly maintained building."
Reviewed on Sep 21, 2026
Hotel Floyd
300 Rick Lewis Way Floyd VA
Fully refundableReserve now, pay when you stay
$132 nightly
$146 total
Sep 27 - Sep 28
Total with taxes and fees
9.8/10 Exceptional! (541 reviews)
"Outstanding value- excellent facility"
Reviewed on Sep 20, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Mayo River Vacation Packages
Mayo River Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Piedmont Triad Intl. Airport (GSO) |
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Frequently asked questions
How much does a Mayo River vacation package cost?
You'll find cheap prices from $535 on Expedia for your Mayo River getaway. However, a range of factors like the season, choice of hotel and length of stay will determine how much your vacation to Mayo River costs.
What are the cheapest months to go to Mayo River?
March, August and December are the best times to look for cheap Mayo River vacation packages. Choosing to travel in quieter periods means you'll typically find lower prices on flights and hotels.
How many days is enough for Mayo River?
Typically, a handful of days is enough to explore the top sights during your Mayo River vacation. However, if you prefer to have more time to chill out or go on day tours, consider extending your itinerary.
How to find the best Mayo River package deals?
Bagging a cheap Mayo River package deal is easy with Expedia. After you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, add some filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to discover the most wallet-friendly Mayo River package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are generally lower.
Is it cheaper to book a Mayo River vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your car rental, flight and hotel into one great-value price and enjoy significant savings. You'll generally land a better deal than booking each component separately. And you'll still get the freedom to create a customized Mayo River vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Mayo River?
Secure incredible bargains by reserving your flights ahead of time with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment Mayo River adventure.
How to plan a trip to Mayo River?
- Choose when to travel: Check your schedule and pack your bags. Your favorite time of year and the type of activities available will also help you decide when to visit Mayo River.
- Calculate your budget: Ensure you have enough money to cover everything from transportation and meals to experiences and flights. Your accommodations will likely be the biggest expense during your trip to Mayo River.
- Use our trip planning tool to discover Mayo River: Research every part of your trip to Mayo River with this handy planner. Invite your family and friends to collaborate on a group trip, search for hotels or things to do and make bookings.
- Set the duration of your trip: Start by listing all the attractions you'd like to experience in Mayo River. Then, estimate how long you'll need at each, as well as any travel time.
- Bundle your bookings: With your travel dates in order, you can combine your hotels, car rental, flights and more into a customized Mayo River vacation package.
- Add on excursions and experiences: Have a look at our dedicated travel guide to find some exciting things to do in Mayo River. Book tickets or make reservations as soon as you can to save time and skip the hassle of looking for activities once you arrive.
Does Expedia offer Book Now, Pay Later Mayo River vacation packages?
Set off on your dream escape to Mayo River with our Book Now, Pay Later vacations. No need to save like crazy or wait until the next payday — we've teamed up with online lender Affirm to give you more financial flexibility. Our vacation packages with payment plans allow you to spread the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, you can easily stay on budget and snap up travel deals while they last.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
