Mayo River Vacations from $507

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The Latest Mayo River vacation packages

Price found within the past 48 hours. Click for updated prices.
Studio 6 Extended Stay - Greensboro, NC - I-40

Studio 6 Extended Stay - Greensboro, NC - I-40

$507
per person
Sep 15 - Sep 18
found 21 hours ago
Roundtrip non-stop flight included
Tampa (TPA) to Greensboro (GSO)
5.8/10 (483 reviews)
Love the elevator that gets you to the third floor. Love the attitude of the manager….

Reviewed on Aug 5, 2026

The Shaffner Inn

The Shaffner Inn

$688
per person
Sep 15 - Sep 18
found 1 day ago
Roundtrip non-stop flight included
Tampa (TPA) to Greensboro (GSO)
9.2/10 Wonderful! (230 reviews)
We loved our room (the Piedmont room) at The Shaffner Inn! It was spacious, beautiful, historic and comfortable. The staff were accommodating to all of our needs and the hospitality was outstanding. This was a great place to stay and we thoroughly enjoyed our time there.

Reviewed on Aug 10, 2026

Julian Price House

Julian Price House

Fisher Park
$616
per person
Sep 11 - Sep 14
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Greensboro (GSO)
10/10 Exceptional! (152 reviews)
It was such a beautiful structure. It felt like the suite was designed for comfort and beauty. The gardens were fantastic. There could have been easier access to the electrical outlets. We would stay there again. Interactions with the owner Michael were helpful and pleasant.

Reviewed on Aug 2, 2026

Motel 6 Greensboro, NC - I-40

Motel 6 Greensboro, NC - I-40

$507
per person
Sep 15 - Sep 18
found 1 day ago
Roundtrip non-stop flight included
Tampa (TPA) to Greensboro (GSO)
5.2/10 (609 reviews)
No pude realizar la reservacion por que no tenían las abitación qué yo había elegido ellos cancelaron la reservacion y tuve que reservar en otro hotel muy mal hotel

Reviewed on Aug 11, 2026

MainStay Suites Greensboro

MainStay Suites Greensboro

$562
per person
Sep 15 - Sep 18
found 14 hours ago
Roundtrip non-stop flight included
Tampa (TPA) to Greensboro (GSO)
7.8/10 Good! (1,000 reviews)
The staff was very helpful much better job with the cleaning

Reviewed on Jul 18, 2026

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Stay near popular Mayo River attractions

Reynolds Homestead

You can study the exhibits at Reynolds Homestead, a museum with a story of its own, during your travels to Patrick Springs. Amble around the area's forest or visit its spas.
See properties

Mayo River Hotel Deals

The Lodge at Primland, Auberge Collection

The Lodge at Primland, Auberge Collection

2000 Busted Rock Rd Meadows Of Dan VA
$1,130 nightly
$1,269 total
Sep 3 - Sep 4
Total with taxes and fees
The Lodge at Primland, Auberge Collection
Hampton Inn Eden

Hampton Inn Eden

724 S Van Buren Rd Eden NC
$106 nightly
$118 total
Aug 30 - Aug 31
Total with taxes and fees
8.8/10 Excellent! (476 reviews)
"clean room"

Reviewed on Aug 7, 2026

Hampton Inn Eden
Hotel Floyd

Hotel Floyd

300 Rick Lewis Way Floyd VA
$132 nightly
$146 total
Aug 16 - Aug 17
Total with taxes and fees
Hotel Floyd
See all 277 properties in Mayo River
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mayo River Vacation Packages

Mayo River Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Piedmont Triad Intl. Airport (GSO)

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Frequently asked questions

How much does a Mayo River vacation package cost?
You'll find cheap prices from $507 on Expedia for your Mayo River getaway. However, a range of factors like the season, choice of hotel and length of stay will determine how much your vacation to Mayo River costs.
What are the cheapest months to go to Mayo River?
March, August and December are the best times to look for cheap Mayo River vacation packages. Choosing to travel in quieter periods means you'll typically find lower prices on flights and hotels.
How many days is enough for Mayo River?
Typically, a handful of days is enough to explore the top sights during your Mayo River vacation. However, if you prefer to have more time to chill out or go on day tours, consider extending your itinerary.
How to find the best Mayo River package deals?
Bagging a cheap Mayo River package deal is easy with Expedia. After you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, add some filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to discover the most wallet-friendly Mayo River package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are generally lower.
Is it cheaper to book a Mayo River vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your car rental, flight and hotel into one great-value price and enjoy significant savings. You'll generally land a better deal than booking each component separately. And you'll still get the freedom to create a customized Mayo River vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Mayo River?
Secure incredible bargains by reserving your flights ahead of time with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment Mayo River adventure.
How to plan a trip to Mayo River?
  1. Choose when to travel: Check your schedule and pack your bags. Your favorite time of year and the type of activities available will also help you decide when to visit Mayo River.
  2. Calculate your budget: Ensure you have enough money to cover everything from transportation and meals to experiences and flights. Your accommodations will likely be the biggest expense during your trip to Mayo River.
  3. Use our trip planning tool to discover Mayo River: Research every part of your trip to Mayo River with this handy planner. Invite your family and friends to collaborate on a group trip, search for hotels or things to do and make bookings.
  4. Set the duration of your trip: Start by listing all the attractions you'd like to experience in Mayo River. Then, estimate how long you'll need at each, as well as any travel time.
  5. Bundle your bookings: With your travel dates in order, you can combine your hotels, car rental, flights and more into a customized Mayo River vacation package.
  6. Add on excursions and experiences: Have a look at our dedicated travel guide to find some exciting things to do in Mayo River. Book tickets or make reservations as soon as you can to save time and skip the hassle of looking for activities once you arrive.
Does Expedia offer Book Now, Pay Later Mayo River vacation packages?
Set off on your dream escape to Mayo River with our Book Now, Pay Later vacations. No need to save like crazy or wait until the next payday — we've teamed up with online lender Affirm to give you more financial flexibility. Our vacation packages with payment plans allow you to spread the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, you can easily stay on budget and snap up travel deals while they last.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.