Mayo River Vacations from $299

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The Latest Mayo River vacation packages

Price found within the past 48 hours. Click for updated prices.
Dailey Renewal Retreat Bed & Breakfast

Dailey Renewal Retreat Bed & Breakfast

3 out of 5
Lindley Park
Price was $361, price is now $299 per person
$299
per person
Jan 9 - Jan 11
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Greensboro (GSO)
9/10 Wonderful! (204 reviews)
This place will always be near and dear to my heart. The breakfast was absolutely delicious, the atmosphere was so cozy and loving I did not want to leave. It was a pleasure to meet Miss Jean Dailey and I hope to come back some time soon. Plus, the house is surrounded by some VERY delicious options for food. If you’re looking for a home-away-from-home getaway, that actually isn’t in the middle of nowhere, I highly recommend!

Reviewed on Aug 5, 2025

Julian Price House

Julian Price House

3 out of 5
Fisher Park
Price was $983, price is now $325 per person
$325
per person
Jan 9 - Jan 11
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Greensboro (GSO)
10/10 Exceptional! (107 reviews)
From the start, I knew this was not a another mondain, casual experience. The historical charm, quaint decor and extremely manicured property became soothing and transcended us back in time. Just WOW! The online pictures are accurate but the experiencing the history and beauty of this mansion is amazing.

Reviewed on Sep 30, 2025

O.Henry Hotel

O.Henry Hotel

4 out of 5
Price was $547, price is now $408 per person
$408
per person
Jan 9 - Jan 11
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Greensboro (GSO)
9.8/10 Exceptional! (712 reviews)
Everything was perfect!!

Reviewed on Sep 30, 2025

Hawthorne Inn and Conference Center

Hawthorne Inn and Conference Center

3 out of 5
Price was $424, price is now $333 per person
$333
per person
Jan 22 - Jan 26
found 22 hours ago
Roundtrip flight included
New York (NYC) to Greensboro (GSO)
8.4/10 Very Good! (1,028 reviews)
Nice clean room, easy parking, friendly staff. Good hotel

Reviewed on Nov 2, 2025

Courtyard by Marriott Winston-Salem University

Courtyard by Marriott Winston-Salem University

3 out of 5
Price was $448, price is now $368 per person
$368
per person
Jan 22 - Jan 26
found 22 hours ago
Roundtrip flight included
New York (NYC) to Greensboro (GSO)
8.6/10 Excellent! (739 reviews)
Great customer service by Nikki

Reviewed on Oct 19, 2025

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Discover the most popular places to visit in Mayo River

The Reynolds Homestead, built in 1943 is in a beautiful foothill setting. Hardin Reynolds and his wife produced 16 children here, the most famous being RJ Reynolds who migrated to Winston Salem, NC to start the tobacco empire of the same name. The catalpa tree in the foreground still remains from the earliest days of the homestead.

Reynolds Homestead

You can study the exhibits at Reynolds Homestead, a museum with a story of its own, during your travels to Patrick Springs. Amble around the area's forest or visit its spas.

Reynolds Homestead

Mayo River Hotel Deals

The Lodge at Primland, Auberge Collection

The Lodge at Primland, Auberge Collection

5 out of 5
2000 Busted Rock Rd, Meadows Of Dan, VA
$587 nightly
The price is $654 total per night from Dec 3 to Dec 4
$654 total
Dec 3 - Dec 4
Total with taxes and fees
9/10 Wonderful! (24 reviews)
The Primland Resort is second to none.
Our first stay at Primland Resort was beautiful, peaceful, and fun. Our second honeymoon after 20 years was better than our first. The Service was wonderful, the food, impeccable, we had privacy, yet met many wonderful people. We will be back!

Reviewed on Mar 13, 2025

The Lodge at Primland, Auberge Collection
Baymont by Wyndham Eden

Baymont by Wyndham Eden

2.5 out of 5
716 Linden Dr, Eden, NC
Fully refundableReserve now, pay when you stay
$83 nightly
The price is $93 total per night from Nov 23 to Nov 24
$93 total
Nov 23 - Nov 24
Total with taxes and fees
8.4/10 Very Good! (540 reviews)
Very clean room and hotel. Friendly and professional staff. Good breakfast.

Reviewed on Oct 28, 2025

Baymont by Wyndham Eden
Hampton Inn Eden

Hampton Inn Eden

2.5 out of 5
724 S Van Buren Rd, Eden, NC
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $128 total per night from Nov 23 to Nov 24
$128 total
Nov 23 - Nov 24
Total with taxes and fees
8.6/10 Excellent! (430 reviews)
Staff was great!! Rooms were large and very clean!!

Reviewed on Oct 31, 2025

Hampton Inn Eden
See all 274 properties in Mayo River
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mayo River Vacation Packages

Mayo River Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Piedmont Triad Intl. Airport (GSO)

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Frequently asked questions

How much does a Mayo River vacation package cost?
You'll find cheap prices from $299 on Expedia for your Mayo River getaway. However, a range of factors like the season, choice of hotel and length of stay will determine how much your vacation to Mayo River costs.
What are the cheapest months to go to Mayo River?
March, August and December are the best times to look for cheap Mayo River vacation packages. Choosing to travel in quieter periods means you'll typically find lower prices on flights and hotels.
How many days is enough for Mayo River?
Typically, a handful of days is enough to explore the top sights during your Mayo River vacation. However, if you prefer to have more time to chill out or go on day tours, consider extending your itinerary.
How to find the best Mayo River package deals?
Bagging a cheap Mayo River package deal is easy with Expedia. After you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, add some filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to discover the most wallet-friendly Mayo River package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are generally lower.
Is it cheaper to book a Mayo River vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your car rental, flight and hotel into one great-value price and enjoy significant savings. You'll generally land a better deal than booking each component separately. And you'll still get the freedom to create a customized Mayo River vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Mayo River?
Secure incredible bargains by reserving your flights ahead of time with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment Mayo River adventure.
How to plan a trip to Mayo River?

  1. Choose when to travel: Check your schedule and pack your bags. Your favorite time of year and the type of activities available will also help you decide when to visit Mayo River.
  2. Calculate your budget: Ensure you have enough money to cover everything from transportation and meals to experiences and flights. Your accommodations will likely be the biggest expense during your trip to Mayo River.
  3. Use our trip planning tool to discover Mayo River: Research every part of your trip to Mayo River with this handy planner. Invite your family and friends to collaborate on a group trip, search for hotels or things to do and make bookings.
  4. Set the duration of your trip: Start by listing all the attractions you'd like to experience in Mayo River. Then, estimate how long you'll need at each, as well as any travel time.
  5. Bundle your bookings: With your travel dates in order, you can combine your hotels, car rental, flights and more into a customized Mayo River vacation package.
  6. Add on excursions and experiences: Have a look at our dedicated travel guide to find some exciting things to do in Mayo River. Book tickets or make reservations as soon as you can to save time and skip the hassle of looking for activities once you arrive.

Does Expedia offer Book Now, Pay Later Mayo River vacation packages?
Set off on your dream escape to Mayo River with our Book Now, Pay Later vacations. No need to save like crazy or wait until the next payday — we've teamed up with online lender Affirm to give you more financial flexibility. Our vacation packages with payment plans allow you to spread the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, you can easily stay on budget and snap up travel deals while they last.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.