Mayo River Vacations from $417

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The Latest Mayo River vacation packages

Price found within the past 48 hours. Click for updated prices.
OYO Inn Kernersville

OYO Inn Kernersville

2.5 out of 5
Price was $510, price is now $417 per person
$417
per person
May 28 - Jun 1
found 24 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Greensboro (GSO)
7/10 Good! (378 reviews)
Room was fine for price the price they asked at hotel was too high but water was very hot and was great for shower...book online for a decent rate

Reviewed on Jan 6, 2026

Hampton Inn Greensboro-Airport

Hampton Inn Greensboro-Airport

3 out of 5
Price was $908, price is now $648 per person
$648
per person
May 28 - Jun 1
found 24 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Greensboro (GSO)
8.8/10 Excellent! (780 reviews)
Friendly staff. Good breakfast and coffee available all day and night.

Reviewed on Apr 2, 2026

Arcade Kid Friendly Firepit Grill HotTub

Arcade Kid Friendly Firepit Grill HotTub

3.5 out of 5
Save 100% on your flight
Price was $2,051, price is now $1,524 per person
$1,524
per person
May 28 - May 31
found 2 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Greensboro (GSO)
No reviews
Proximity Hotel

Proximity Hotel

4 out of 5
Price was $1,062, price is now $805 per person
$805
per person
May 28 - Jun 1
found 24 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Greensboro (GSO)
9.8/10 Exceptional! (975 reviews)
This establishment is the best in the city. Me and my family enjoy it so much, it’s our third time staying there. I hope to soon do a honeymoon weekend that they offer.

Reviewed on Apr 5, 2026

O.Henry Hotel

O.Henry Hotel

4 out of 5
Price was $1,099, price is now $843 per person
$843
per person
May 28 - Jun 1
found 24 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Greensboro (GSO)
9.8/10 Exceptional! (776 reviews)
Our favorite hotel - always wonderful and always consistent - the friendliest, most accommodating staff and lots of places to relax

Reviewed on Apr 5, 2026

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Discover the most popular places to visit in Mayo River

Reynolds Homestead

Reynolds Homestead

You can study the exhibits at Reynolds Homestead, a museum with a story of its own, during your travels to Patrick Springs. Amble around the area's forest or visit its spas.

Reynolds Homestead

Mayo River Hotel Deals

The Lodge at Primland, Auberge Collection

The Lodge at Primland, Auberge Collection

5 out of 5
2000 Busted Rock Rd Meadows Of Dan VA
$753 nightly
The price is $846 total per night from Apr 22 to Apr 23
$846 total
Apr 22 - Apr 23
Total with taxes and fees
9/10 Wonderful! (31 reviews)
Star gazing & wine tasting was amazing! Staff extremely helpful. Excellent food. Check into the activities available for each day of your stay BEFORE you get there. Book early since the number of people for each activity can be limited. Some activities only available certain days.

Reviewed on Mar 21, 2026

The Lodge at Primland, Auberge Collection
Comfort Inn Martinsville

Comfort Inn Martinsville

3 out of 5
378 Commonwealth Blvd W Martinsville VA
Fully refundable
$118 nightly
The price is $132 total per night from May 10 to May 11
$132 total
May 10 - May 11
Total with taxes and fees
6.8/10 (642 reviews)
Ok

Reviewed on Apr 12, 2026

Comfort Inn Martinsville
Hotel Floyd

Hotel Floyd

2 out of 5
300 Rick Lewis Way Floyd VA
Fully refundableReserve now, pay when you stay
$121 nightly
The price is $133 total per night from Apr 14 to Apr 15
$133 total
Apr 14 - Apr 15
Total with taxes and fees
9.6/10 Exceptional! (504 reviews)
The room was clean, eclectic, had some older features, like mattress, bathroom fixtures, but it had a homey feel with interesting furniture pieces. Very comfortable.

Reviewed on Apr 4, 2026

Hotel Floyd
See all 271 properties in Mayo River
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mayo River Vacation Packages

Mayo River Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Piedmont Triad Intl. Airport (GSO)

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Frequently asked questions

How much does a Mayo River vacation package cost?
You'll find cheap prices from $417 on Expedia for your Mayo River getaway. However, a range of factors like the season, choice of hotel and length of stay will determine how much your vacation to Mayo River costs.
What are the cheapest months to go to Mayo River?
March, August and December are the best times to look for cheap Mayo River vacation packages. Choosing to travel in quieter periods means you'll typically find lower prices on flights and hotels.
How many days is enough for Mayo River?
Typically, a handful of days is enough to explore the top sights during your Mayo River vacation. However, if you prefer to have more time to chill out or go on day tours, consider extending your itinerary.
How to find the best Mayo River package deals?
Bagging a cheap Mayo River package deal is easy with Expedia. After you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, add some filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to discover the most wallet-friendly Mayo River package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are generally lower.
Is it cheaper to book a Mayo River vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your car rental, flight and hotel into one great-value price and enjoy significant savings. You'll generally land a better deal than booking each component separately. And you'll still get the freedom to create a customized Mayo River vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Mayo River?
Secure incredible bargains by reserving your flights ahead of time with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment Mayo River adventure.
How to plan a trip to Mayo River?

  1. Choose when to travel: Check your schedule and pack your bags. Your favorite time of year and the type of activities available will also help you decide when to visit Mayo River.
  2. Calculate your budget: Ensure you have enough money to cover everything from transportation and meals to experiences and flights. Your accommodations will likely be the biggest expense during your trip to Mayo River.
  3. Use our trip planning tool to discover Mayo River: Research every part of your trip to Mayo River with this handy planner. Invite your family and friends to collaborate on a group trip, search for hotels or things to do and make bookings.
  4. Set the duration of your trip: Start by listing all the attractions you'd like to experience in Mayo River. Then, estimate how long you'll need at each, as well as any travel time.
  5. Bundle your bookings: With your travel dates in order, you can combine your hotels, car rental, flights and more into a customized Mayo River vacation package.
  6. Add on excursions and experiences: Have a look at our dedicated travel guide to find some exciting things to do in Mayo River. Book tickets or make reservations as soon as you can to save time and skip the hassle of looking for activities once you arrive.

Does Expedia offer Book Now, Pay Later Mayo River vacation packages?
Set off on your dream escape to Mayo River with our Book Now, Pay Later vacations. No need to save like crazy or wait until the next payday — we've teamed up with online lender Affirm to give you more financial flexibility. Our vacation packages with payment plans allow you to spread the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, you can easily stay on budget and snap up travel deals while they last.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.