South Carolina may have travel restrictions in place due to COVID-19.

Find out moreOpens in new tab or window

Search Guest Houses in Mount Pleasant

Search over 1 million properties and 550 airlines worldwide

Members save 10% more on select hotels, cars, activities and vacation rentals. Sign up.

Free cancellation on most hotels. Because flexibility matters.

Featured Guest Houses in Mount Pleasant

Newly Renovated Detached Garage Studio Apartment 5 Miles From Downtown!
Newly Renovated Detached Garage Studio Apartment 5 Miles From Downtown!
Mount Pleasant, SC
Get Rates

Situated in Mount Pleasant, this guesthouse is 2.1 mi (3.4 km) from Mount Pleasant Memorial Waterfront Park and 2.4 mi (3.8 km) from Shem Creek Park. Patriots ...…

5/5Exceptional! (7 reviews)
Home away from Home!

"Our cozy place was perfect! We stayed for one month and it was great! The neighborhood is easy for walking with beautiful trails and homes. Close to shopping and other attractions, we were able to zip into Charleston quickly, by just going over the Ravenel Bridge. Rental owners were wonderful, friendly ..."…"

Reviewed on Apr 1, 2020

Newly Renovated Detached Garage Studio Apartment 5 Miles From Downtown!
Cute & Cozy Guest House in a Great Location
Cute & Cozy Guest House in a Great Location
Mount Pleasant, SC
Get Rates

Located in Old Village, this guesthouse is 0.8 mi (1.2 km) from Mount Pleasant Sports Complex and within 3 mi (5 km) of Tolers Cove Marina and Shem Creek Park. ...…

5/5Exceptional! (2 reviews)
Short Getaway

"Internet connection for the smart was spotty at first but owner took care of that problem very quick and never had another issue. Guesthouse was very cozy and clean."…"

Reviewed on Feb 11, 2020

Cute & Cozy Guest House in a Great Location
Upscale Couple's Retreat Beach & Downtown CHS
Upscale Couple's Retreat Beach & Downtown CHS
Mount Pleasant, SC
The price is $166 per night

Located in Old Village, this guesthouse is 0.9 mi (1.5 km) from Mount Pleasant Sports Complex and within 3 mi (5 km) of Shem Creek Park and Tolers Cove Marina. ...…

5/5Exceptional! (3 reviews)
Wonderful property!

"The apartment was so clean and well equippied. In a excellent neighborhood. So close to the beach and attractions but yet sit in a private area. Owner was available for any need ! FIVE STARS ALL THE WAY !"…"

Reviewed on Jul 3, 2020

Upscale Couple's Retreat Beach & Downtown CHS
Don't see what you're looking for?
See all available properties in Mount Pleasant
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other property types in Mount Pleasant

Harborside at Charleston Harbor Resort and Marina
Harborside at Charleston Harbor Resort and Marina
4 out of 5
20 Patriots Point Rd, Mount Pleasant, SC
4/5Very Good! (1,341 reviews)

"The stay was nice and everything felt clean! The room was nice and beds were comfortable."…"

Reviewed on Aug 4, 2020

Harborside at Charleston Harbor Resort and Marina
Best Western Patriots Point
Best Western Patriots Point
2.5 out of 5
259 McGrath Darby Blvd, Mount Pleasant, SC
The price is $65 per night
3.8/5Good! (939 reviews)

"For the price is was good. A little dated but didn't pay like a new hotel. Staff very friendly. No issues."…"

Reviewed on Jul 27, 2020

Best Western Patriots Point
Cambria Hotel Mount Pleasant – Charleston
Cambria Hotel Mount Pleasant – Charleston
3 out of 5
1472 Highway 17 North, Mount Pleasant, SC
The price is $110 per night
4.7/5Exceptional! (337 reviews)

"The property was nice. I loved the look of the room."…"

Reviewed on Aug 4, 2020

Cambria Hotel Mount Pleasant – Charleston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More trip options