Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5
Start by selecting your hotel
Start by selecting your hotel
Start by selecting your hotel

Search over 1,000,000 properties worldwide and 550 airlines worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Murphysboro Vacation Packages

Save Time and Money with Murphysboro Vacation Packages

Get instant savings by booking a Murphysboro travel package. Just pick out your favorite options and let Expedia do the rest.

By securing a package deal on Expedia, you can save up to $583*.

Within a matter of minutes, you'll be able to organize everything you'll need for your next trip through our extensive database. And — with more than 550 partner airlines and 750,000 properties from across the world, you'll have the freedom to pick and choose!

Almost all reservations can be cancelled with no extra charge from us.

Places to Visit in Murphysboro

We've got all the hot sightseeing tips for your trip to Murphysboro. Grab your travel diary and get ready to start filling your itinerary.

Time spent in nature has been shown to enhance both your spiritual and physical well-being. Visit Lake Murphysboro State Park and experience the benefits of reconnecting with our natural environment. Still got time to spare? Leave the history journals! Witness the past jump to life at General John A. Logan Museum.

Nearest Airports to Murphysboro

From the very second you finally exit the plane at MidAmerica-St. Louis Airport (BLV), you'll know your unforgettable trip to Murphysboro has started at last! Well, the neighborhood center is still approximately 60 miles (97 km) away, but close enough.

*Savings based on all vacation package bookings with Flight + Hotel on Expedia.com from January through December 2017, as compared to price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages. For Free Flight or 100% Off Flight deals, package savings is greater than or equal to the current cost of one component, when both are priced separately.


Top Deals on Flights

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.