Otay Mesa Vacations from $248
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The Latest Otay Mesa Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Best Western Carlsbad by the Sea
South Beach
Price was $473, price is now $248 per person
$248
per person
Jan 22 - Jan 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8/10 Very Good! (1,010 reviews)
Nice hotel. Easy access to everything. I have stayed here a few times. A little noisy in certain rooms, make sure to ask for a room facing the pool or Avenida street. Breakfast from 6-9 am. Fitness center is good, pool is clean. I will stay here again.
Reviewed on Nov 30, 2025
La Jolla Beach and Tennis Club
La Jolla Shores
Price was $2,896, price is now $1,355 per person
$1,355
per person
Feb 16 - Feb 20
found 1 day ago
Roundtrip flight included
Chicago (CHI) to San Diego (SAN)
8.8/10 Excellent! (485 reviews)
Fabulous place. Marine Room dining exquisite.
Breakfast at the restaurant was only a “C”.
Reviewed on Nov 23, 2025
The Sofia Hotel
Downtown San Diego
Save 100% on your flight
Price was $719, price is now $358 per person
$358
per person
Feb 16 - Feb 20
found 1 day ago
Roundtrip flight included
Chicago (CHI) to San Diego (SAN)
8.4/10 Very Good! (1,627 reviews)
Rooms felt clean, staff was pretty friendly, and the bike rental was a plus (1hr limit). Convenient location as well - was very walkable to all points in the area and there were a few bus stops nearby. Only downside was the light that came through the windows. There were blackout curtains but with the way the hutch with TV on it was positioned, you couldn't pull the curtains closed behind it. Enjoyed the history of the building and the quirkiness of the staircases (they didn't all go down to ground floor). Decent hotel gym as well and I enjoyed the yoga area to stretch out post run.
Reviewed on Dec 4, 2025
Quiet Mind Mountain Lodge, Retreat and Spa
Price was $633, price is now $317 per person
$317
per person
Jan 22 - Jan 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9.2/10 Wonderful! (558 reviews)
The room has a nice calm and peaceful vibe. Overall, liked the stay.
Reviewed on Nov 25, 2025
La Jolla Shores Hotel
La Jolla Shores
Save 100% on your flight
Price was $1,521, price is now $848 per person
$848
per person
Jan 9 - Jan 15
found 1 day ago
Roundtrip flight included
Chicago (CHI) to San Diego (SAN)
8.8/10 Excellent! (1,370 reviews)
It gets you on the water but not 4 or 5 star resort. Would have been cool if they let you know the facility was under major construction. We made the best of it.
Restaurant and bar are spot on. We had a couple of drinks the first night in the bar and breakfast down stairs on our way out. Location is great away from the big crowds but everything is walking distance. Booked it as we were driving down south for a couple of days. We would stay again once construction is done.
Reviewed on Dec 2, 2025
Where to stay in Otay Mesa
Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa
Downtown San Diego
3 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
Otay Mesa Hotel Deals
Hotel del Coronado, Curio Collection by Hilton
1500 Orange Ave Coronado CA
Fully refundableReserve now, pay when you stay
$389 nightly
The price is $432 total per night from Jan 4 to Jan 5
$432 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
8.4/10 Very Good! (1,020 reviews)
Beautiful rooms, great activities, wonderful staff
Reviewed on Nov 29, 2025
Legacy Resort Hotel & Spa
875 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $175 total per night from Dec 7 to Dec 8
$175 total
Dec 7 - Dec 8
Total with taxes and fees
9/10 Wonderful! (2,983 reviews)
Friendly, staff was very helpful, great size rooms, and over all was an amazing stay
Reviewed on Dec 1, 2025
Hampton Inn & Suites by Hilton San Diego SeaWorld
3888 Greenwood St San Diego CA
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $140 total per night from Dec 11 to Dec 12
$140 total
Dec 11 - Dec 12
Total with taxes and fees
9/10 Wonderful! (375 reviews)
Very clean!
Reviewed on Dec 2, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Otay Mesa
San Diego Zoo
4.5/5(3,565 reviews)
See nature up-close and personal at one of the country’s largest and most educational zoos.
San Diego Convention Center
4.5/5(1,297 reviews)
Whether you come for Comic-Con or a medical convention, this huge gathering place in the Marina District of San Diego will more than satisfy your needs.
Mission Bay
4.5/5(2,386 reviews)
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Things to do
From Tijuana: Valle de Guadalupe Private Winery Tour
$136
per adult
Tijuana Mexico Coffee Shop Hop from San Diego
$93
per adult
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.