Find all hotels by Independent in Panama City from $38

The best area to stay in Panama City for most travelers is El Cangrejo, known for its central location and wide array of dining and entertainment options.

El Cangrejo is a popular district characterized by its tree-lined streets, art deco architecture, and numerous restaurants, bars, and cafes. It's centrally located, providing easy access to other parts of the city. Via Argentina is the main thoroughfare, bustling with activity and offering a diverse culinary scene.

This neighborhood is particularly well-suited for solo travelers looking for convenience and a lively option. You'll find many independent cafes superb for working or relaxing, and the area's many restaurants and bars offer ample opportunities to experience local life without venturing far.

For travelers who prefer a more residential feel with high-end amenities, Punta Paitilla is an excellent choice. This waterfront neighborhood features modern high-rise buildings, many with ocean views, and offers a selection of upscale shopping centers and dining.

Two of the best hotels in Panama City that receive consistently high recommendations from travelers are The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City and the American Trade Hotel.

The 5-star The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City, with an impressive 9.6 rating, offers a luxurious experience with amenities like rainfall showerheads, deep soaking bathtubs, and premium bedding. Guests frequently praise the great food, amazing staff, and exceptional customer service. It is also conveniently located less than a mile from Atrio Mall and features an onsite golf course.

Another highly recommended option is the 4.5-star American Trade Hotel, which has a 9.4 rating. This hotel is celebrated for its friendly and helpful staff, central location, and incredible, clean rooms. Guests also enjoy the fabulous food and amazing amenities. It is just a short walk from the Museum of History Panama and the Mola Museum.

For family-friendly hotels in Panama City, consider the Sheraton Grand Panama, Radisson Hotel Panama Canal, Waldorf Astoria Panama, Renaissance Panama City Hotel, and JW Marriott Panama.

The 4-star Sheraton Grand Panama, with an 8.6 rating, offers a pool, a playground for children, and connecting rooms, along with kid's meals and cribs. It is conveniently located near Multiplaza Pacific Mall and Omar Torrijos Recreational Park. Guests frequently praise the nice, quiet rooms and the friendly staff.

The 4.5-star Radisson Hotel Panama Canal, also rated 8.6, provides a children's pool, highchairs, toys for children, and connecting rooms. It is situated close to the Marine Exhibition Center Smithsonian Institute Panama and the Biomuseo.

The 5-star Waldorf Astoria Panama, boasting a 9.0 rating, is well-equipped for families with amenities like bed guards, highchairs, complimentary rollaway extra beds and cribs, and even onsite babysitting services. It features child-friendly window designs and is located in a nice area near Multicentro Panama and Avenida Balboa. Guests consistently highlight the friendly and extremely helpful staff, as well as the spacious and clean rooms.

The 5-star Renaissance Panama City Hotel, with an 8.8 rating, offers a pool, complimentary rollaway extra beds, connecting rooms, cribs, and sofa beds, making it suitable for families. It is located near Avenida Balboa and Multicentro Panama.

The 5-star JW Marriott Panama, with a 9.0 rating, features a pool, a children's pool, complimentary rollaway extra beds, cribs, and sofa beds. It is centrally located near Multiplaza Pacific Mall and Avenida Balboa. Guests often comment on the amazing and friendly staff, beautiful rooms, and excellent food. Find more child-friendly accommodations in Panama City

For luxurious 5-star hotels in Panama City, consider The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City, and Bristol Panama, a Registry Collection Hotel.

The 5-star The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City, boasts an exceptional 9.6 rating. Guests frequently praise its amazing food and friendly staff. This hotel offers a rainfall showerhead, deep soaking bathtubs, and premium bedding for ultimate comfort. With an onsite golf course and a poolside bar, it provides excellent relaxation options, and it's less than a mile from Atrio Mall.

Another outstanding option is the 5-star Bristol Panama, a Registry Collection Hotel, with a 9.2 rating. Travelers often highlight the friendly and attentive staff, great room sizes, and delicious breakfast options. Amenities include an onsite art gallery, designer toiletries, and 24-hour room service. It is conveniently located near Avenida Balboa and Multicentro Panama, both within 0.6 miles. Find more luxury hotels in Panama City

Yes, there is an all-inclusive hotel in Panama City, Hotel Bahia Suites.

The 3.5-star Hotel Bahia Suites, with a 7.0 rating, offers an all-inclusive stay for guests. It provides convenient amenities such as a 24-hour airport shuttle, an area shuttle for exploring the surroundings, and complimentary wired and wireless internet access. Guests also benefit from free toiletries and free self-parking. This hotel is conveniently located near several points of interest, including the Museum of Natural Science, which is just 0.1 miles away, and Cinta Costera, located 0.3 miles from the property. See more all-inclusive resorts in Panama City

For an exceptional spa experience in Panama City, consider the Bristol Panama, a Registry Collection Hotel, and the Hilton Panama.

The 5-star Bristol Panama, a Registry Collection Hotel, boasts an impressive 9.2 rating. Its full-service spa offers a wide array of treatments, including Swedish massage, hot stone massage, aromatherapy treatments, and body wraps, with options for couples' treatment rooms. Guests can also enjoy body scrubs, deep tissue massage, and a sauna. It is conveniently located near Avenida Balboa and Soho City Center.

Another excellent choice is the 5-star Hilton Panama, with an 8.8 rating. This hotel also features a full-service spa where guests can indulge in aromatherapy treatments, hot stone massages, and Swedish massages. The spa includes a hot tub, steam room, and sauna, along with options for couples' treatment rooms, manicures, pedicures, and various body treatments like scrubs and wraps. It is situated close to Avenida Balboa. See all spa hotels in Panama City

For hotels in Panama City that offer free breakfast, consider the Sofitel Legend Casco Viejo, Panama City, the Ramada Plaza by Wyndham Panama Punta Pacifica, Plaza Paitilla Inn Hotel, The Executive Hotel, and TRYP by Wyndham Panamá Centro.

The 5-star Sofitel Legend Casco Viejo, Panama City, boasting an impressive 9.8 rating, offers complimentary breakfast for children. This luxurious hotel features an outdoor pool with sun loungers, a swim-up bar, and a poolside bar, making it a relaxing choice. It also provides a 24-hour airport shuttle service and is conveniently located near the Amador Theater and the Museum of History Panama. Guests frequently praise the attentive staff and excellent service.

The 4-star Ramada Plaza by Wyndham Panama Punta Pacifica, rated 9.6, provides free daily breakfast, including a complimentary buffet. This hotel is conveniently located with nearby outlets and even has a shopping mall on-site. Customers consistently highlight the friendly and helpful staff, as well as the spacious and clean rooms.

The 3.5-star Plaza Paitilla Inn Hotel, with a 9.4 rating, offers free daily breakfast with a complimentary buffet, along with free self-parking and free WiFi. It is situated close to Avenida Balboa and Uruguay Street, making it a great location for exploring. Guests often comment on the comfortable and clean rooms and the fabulous breakfast.

The 3.5-star The Executive Hotel, rated 9.2, includes a complimentary buffet breakfast and free daily breakfast, as well as free self-parking and free WiFi. This hotel is praised for its clean rooms and extremely helpful staff. It's located near the National Shrine of the Heart of Mary and Cinta Costera.

The 3.5-star TRYP by Wyndham Panamá Centro, with a 9.2 rating, provides free breakfast for children. This hotel offers spacious and clean rooms, and guests appreciate the friendly and helpful staff. It features a nice rooftop pool and is located in a nice area, close to the National Shrine of the Heart of Mary and Metropolitan Nature Park. Find more hotels with free breakfast in Panama City

For top pet-friendly hotels in Panama City, consider La Concordia Boutique Hotel, Summit Rainforest & Golf Resort, Riande Urban Hotel, Hotel El Panama by Faranda Grand, a member of Radisson Individuals, and Toscana Inn.

The 4-star La Concordia Boutique Hotel, with an outstanding 9.6 rating, permits both dogs and cats and offers pet grooming and pet sitting services. Guests frequently praise its beautiful, big rooms, the friendly and helpful front desk and staff, and its great location in a beautiful neighborhood. It is conveniently located near the Museum of History Panama and the Mola Museum.

The 4-star Summit Rainforest & Golf Resort, rated 8.4, welcomes dogs and provides food and water bowls. Guests often mention the delicious and good food, excellent breakfast, and beautiful location.

Another excellent option is the 3.5-star Riande Urban Hotel, which has an 8.8 rating. This hotel permits dogs and provides food and water bowls. It is praised for its friendly and great staff, comfortable and clean rooms, and excellent pool. Its convenient and amazing location is near Multicentro Panama and Multiplaza Pacific Mall.

The 4-star Hotel El Panama by Faranda Grand, a member of Radisson Individuals, with a 7.8 rating, is also pet-friendly, welcoming dogs and offering food and water bowls, as well as a dog exercise area. Guests enjoy the great and tasty breakfast, good service, and friendly and helpful staff. It's located near Multicentro Panama and Soho City Center.

Finally, the 3.5-star Toscana Inn, with a 9.0 rating, allows dogs to stay free and provides free toiletries, free WiFi, and wired internet in public areas. Travelers often highlight the friendly and helpful staff, good price, and clean rooms. It is situated near Multicentro Panama and Multiplaza Pacific Mall. See more pet-friendly hotels in Panama City

For top boutique hotels in Panama City, consider the Bristol Panama, a Registry Collection Hotel, the Riande Urban Hotel, and the Ramada Plaza by Wyndham Panama Punta Pacifica.

The 5-star Bristol Panama, a Registry Collection Hotel, boasts an exceptional 9.2 rating. This hotel is praised for its Art Deco design and offers a full-service spa with a variety of treatments, including Swedish massage, hot stone massage, and aromatherapy. Guests frequently praise the friendly and attentive staff, the spacious rooms, and the excellent breakfast. It is conveniently located near Avenida Balboa and Soho City Center.

The 3.5-star Riande Urban Hotel, with an 8.8 rating, is another excellent option. This hotel also features an Art Deco design and offers complimentary breakfast, including a club level buffet breakfast and continental options, along with free WiFi. Travelers frequently highlight the friendly staff, comfortable and clean rooms, and the excellent pool. Its location is considered convenient, close to Avenida Balboa and Luxor Towers.

The 4-star Ramada Plaza by Wyndham Panama Punta Pacifica has an outstanding 9.6 rating. This hotel features a Beaux Arts design and offers convenient on-site shopping options, including a shopping mall and gift shops. Guests consistently praise the friendly and helpful staff, the spacious and clean rooms, and the excellent breakfast buffet. See all boutique hotels in Panama City

For a romantic stay in Panama City, consider the Sofitel Legend Casco Viejo, Panama City, Hotel La Compañía Casco Antiguo, or La Isabela Suites.

The 5-star Sofitel Legend Casco Viejo, Panama City, with an impressive 9.8 rating, offers a truly luxurious experience. Couples can enjoy couples dining options, a swim-up bar, and a beautiful outdoor pool with sun loungers and a poolside bar. It's conveniently located near the Metropolitan Cathedral of Panama and the National Institute of Culture. Guests consistently praise the attentive staff, clean rooms, and excellent service.

Another excellent choice is the 4.5-star Hotel La Compañía Casco Antiguo, also rated 9.8. This hotel provides couples dining, a 24-hour airport shuttle, and premium bedding. It also features a winery with a tasting room and champagne service for a special touch. Situated close to the Metropolitan Cathedral of Panama and Palacio de las Garzas, it's admired for its excellent staff, food, and location.

For a more intimate setting, La Isabela Suites, a 3.5-star hotel with a superb 10.0 rating, is a wonderful option. This hotel offers balconies or patios, terraces, and free toiletries. Guests frequently praise the attentive and extremely helpful staff, the spacious and beautiful suites, and the wonderful amenities. It is located near the Metropolitan Cathedral of Panama and Palacio de las Garzas. See all romantic hotels in Panama City

For hotels in Panama City near Avenida Balboa, consider the Hyatt Regency Panama City, the Sofitel Legend Casco Viejo, Panama City, and La Isabela Suites.

The 4.5-star Hyatt Regency Panama City, with a superb 10.0 rating, is conveniently located just 0.7 miles from Avenida Balboa. This hotel features an outdoor pool and offers free WiFi, ensuring a comfortable stay.

Another excellent option is the 5-star Sofitel Legend Casco Viejo, Panama City, rated 9.8. While a bit further at 2.1 miles from Avenida Balboa, it offers a superb experience with an outdoor pool, a swim-up bar, and complimentary breakfast for children. The staff are frequently praised for being attentive, and the rooms are described as clean and amazing.

La Isabela Suites, a 3.5-star property with a superb 10.0 rating, is located 2.2 miles from Avenida Balboa. This hotel provides a 24-hour airport shuttle, balconies or patios, and a terrace. Guests consistently highlight the attentive and helpful staff, as well as the spacious and beautiful suites.

While Panama City is generally a year-round destination, the best time to visit is during the dry season, which runs from mid-December to mid-April. This period offers the most pleasant weather for exploring the city and its surroundings.

During the dry season, you can expect sunny days with lower humidity and minimal rainfall, making it ideal for sightseeing, walking around Casco Viejo, and enjoying outdoor activities. Temperatures are consistently warm, typically ranging from the mid-70s to high 80s Fahrenheit (24-31°C).

Travelers who prefer to avoid the peak tourist crowds and don't mind occasional rain showers might consider visiting during the shoulder months of May or early December.

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Panama City.

Prices for hotels in Panama City often vary, but you can find a great deal from $38 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.