San Polo Vacations from $1,321

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Your San Polo Vacation

With a customized vacation package to San Polo, you'll spend less time planning and more time simply enjoying this interesting neighborhood. From its markets to its gift and craft shops, there's plenty to discover here. Hoping to explore the sights during your trip to San Polo? Be sure to stop by nearby attractions such as Rialto Bridge, St. Marks Basilica and St. Marks Square. Stop dreaming and start doing. When it's time to lock in your next vacation to San Polo, Expedia is here to help.

The Latest San Polo Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Ca' Sagredo

Ca' Sagredo

Cannaregio
$1,321
per person
Nov 25 - Nov 29
found 18 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
9.2/10 Wonderful! (523 reviews)
Eurostars Cannaregio

Eurostars Cannaregio

Cannaregio
Save 100% on your flight
$1,891
per person
Oct 10 - Oct 14
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
8.6/10 Excellent! (1,017 reviews)
Excellent room, big, clean and beautiful. Amazing breakfast. Beautiful property in and out! 10 out of 10. Excellent value for the money.

Reviewed on Aug 28, 2026

Hotel Bisanzio

Hotel Bisanzio

Castello
$1,651
per person
Oct 21 - Oct 26
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
9/10 Wonderful! (1,001 reviews)
Hotel San Moisè

Hotel San Moisè

Venice City Center
Save 100% on your flight
$1,826
per person
Oct 21 - Oct 26
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
7.8/10 Good! (749 reviews)
We expected more.

Reviewed on Aug 27, 2026

Palazzo Dei Fiori By Room Mate

Palazzo Dei Fiori By Room Mate

Venice City Center
$1,543
per person
Oct 15 - Oct 19
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
10/10 Exceptional! (86 reviews)
Exceptional Stay in the Heart of Venice We stayed at Palazzo Dei Fiori by Room Mate (early August 2026) in the Girasole apartment, and the entire experience far exceeded our expectations. The Apartment (Girasole) -Space & Layout: The 3-bedroom setup (1 king, 2 double) with 3 private bathrooms provided unmatched comfort and privacy for our group. -Views & Comfort: Beautiful canal views directly from the apartment and effective, climate-controlled air conditioning; an absolute necessity during an August stay in Venice. -Location: Perfectly situated in the city center, offering quiet surroundings while remaining just a short walk from the Grand Canal. Service & Hospitality -Seamless Arrival: Check-in was fast, straightforward, and welcoming from the moment we arrived. -Attentive Staff: The front desk team was consistently available, proactive, and genuinely eager to assist at every turn. -Coordination & Local Insight: They handled our airport transfers flawlessly, arranged seamless transport to the neighboring islands, and pointed us to fantastic local dining spots that made our trip memorable. Palazzo Dei Fiori delivered top-tier accommodations, prime location, and world-class service. We would rebook without hesitation!!

Reviewed on Aug 28, 2026

Where to stay in San Polo

Find the best San Polo areas and neighborhoods for the activities you enjoy most. Learn more about San Polo
A historic building with a dome and bell tower by the water.

Venice City Center

5 out of top 10 points of interest in this area

Discover an abundance of architectural monuments and great art by grandmasters in the heart of an Italian city built on water.

A canal with gondolas, people walking on the steps, and storefronts with signs like "Giorgio Armani".

San Marco

In the heart of Venice, this densely built area boasts iconic attractions like St Mark's Square, Saint Mark's Basilica, and the Doge's Palace. Find numerous hotels, banks, and high-end shops amid the bustling tourist scene.

A canal in Venice with colorful buildings and a bridge.

Cannaregio

Explore historic churches like Santa Maria di Nazareth and Santa Maria dei Miracoli, or admire stunning palazzos such as Ca' d'Oro and Ca' Vendramin Calergi. Enjoy morning markets, local shops, and quaint cafés in this residential, peaceful district.

A canal with a bridge, buildings with blue shutters, and a sign in Italian.

Dorsoduro

Boasting the highest land areas in Venice, this sestiere features the stunning Basilica of Santa Maria della Salute and the picturesque Zattere quay. Easily connect to San Marco via Ponte dell'Accademia.

A narrow canal flanked by historic buildings with arched windows and balconies.

Santa Croce

1 out of top 10 points of interest in this area

In the northwestern part of Venice, Santa Croce boasts a mix of medieval charm in the east and 20th-century land reclamation in the west. Explore churches like San Giacomo dell'Orio and visit the Museum of the History of Fabric and Costume, while enjoying the convenience of Piazzale Roma's transportation hub.

San Polo Hotel Deals

Hotel Guerrato

Hotel Guerrato

Calle Drio La Scimia 240a Venice VE
Fully refundableReserve now, pay when you stay
$94 nightly
$112 total
Sep 1 - Sep 2
Total with taxes and fees
9.2/10 Wonderful! (1,000 reviews)
"The hotel was very close to boat bus,water taxi.there is no refrigerator in room and no tv.very quaint hotel and unique setting"

Reviewed on Aug 29, 2026

Hotel Guerrato
H10 Palazzo Canova

H10 Palazzo Canova

San Polo - Via Riva del Vin 744 Venice VE
$474 nightly
$532 total
Sep 1 - Sep 2
Total with taxes and fees
H10 Palazzo Canova
Hotel Palazzetto Madonna

Hotel Palazzetto Madonna

San Polo, 2902 Venice VE
$293 nightly
$333 total
Sep 1 - Sep 2
Total with taxes and fees
9.2/10 Wonderful! (1,001 reviews)
"Overall our stay was fine. The staff were friendly enough and the hotel itself was sufficient for our stay. Pros - Really yummy breakfast was included every day, the location was close to sites, restaurants, and the waterbus/vaporetto dock, and there is a garden terrace space within the hotel. Cons ..."

Reviewed on Aug 30, 2026

Hotel Palazzetto Madonna
See all 6,494 properties in San Polo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular San Polo attractions

A historic Venetian building with ornate architecture, a canal, and boats.

Palazzo Pisani Moretta

You can find out about the history of Venice with a stop at Palazzo Pisani Moretta. Visit the area's churches or amble around its marina.
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A street with trees and buildings.
Photo by Catherine Slee

Scuola Grande di San Rocco

7.6/10 (13 reviews)
You can browse the exhibits at Scuola Grande di San Rocco, a museum with a storied past, during your trip to Venice. Stroll along the area's marina or experience its acclaimed art scene.
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Rialto Market

9.0/10 (16 reviews)
You can find the perfect gifts to bring home at Rialto Market during your stay in Venice. Stroll along the marina or visit the churches in the area.
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Basilica di Santa Maria Gloriosa dei Frari

9.0/10 (345 reviews)
Find out about the history of Venice when you take a trip to Basilica di Santa Maria Gloriosa dei Frari. Visit the area's churches or amble around its marina.
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Scuola Grande di San Giovanni Evangelista

8.0/10 (1 review)
Enjoy a show at Scuola Grande di San Giovanni Evangelista, a theater with a story to tell in Venice. Stroll along the marina or visit the churches in the area.
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San Cassiano

10.0/10 (1 review)
Learn about the local history of Venice when you spend time at San Cassiano. Experience the area's acclaimed art scene and fascinating museums.
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Campo San Polo

You can learn about the history of Venice with a stop at Campo San Polo. Stroll along the marina or visit the churches in the area.
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San Toma Waterbus

10.0/10 (1 review)
Explore the waterfront of San Toma Waterbus and enjoy other activities such as boating in Venice. Discover the area's acclaimed art scene and churches.
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Things to do

Taste of Venice: Local Tapas Tastings & Wine Tour

Venice Small Group Food Tour: Venetian Tapas, Wine, Spritz & Gondola Ride

$92
per adult
96% of travellers recommend
Venice Small Group Food Tour: Venetian Tapas, Wine, Spritz & Gondola Ride
Sidewalk flanked by colorful buildings in Burano

Murano & Burano Tour

$41
per adult
90% of travellers recommend
Murano & Burano Tour
Sunset Cruise with Aperitivo & Lagoon Views

Sunset Cruise with Aperitivo & Lagoon Views

$34
per adult
Sunset Cruise with Aperitivo & Lagoon Views
See all activities in Venice

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.