Search Vacation Homes in Santa Isabel

Start date: Check-in selected.
To Date
End date: Check-out
  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals
  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings
  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
In two months
In three months
In four months

Vacation Homes in Santa Isabel

Vacation Home in Santa Isabel

10.0 out of 10, Exceptional, (1)
"Our stay at Mimi’s VRBO was unforgettable, and we’re already planning our return! After searching for the ideal family rental, we chose Mimi’s listing and it was a game-changer. Her warmth and quick responses made everything seamless. When our flight was delayed, Mimi arranged a car to get us to the property and coordinated a rental car delivery the next morning.The house is a gem in a safe, friendly neighborhood, steps from Walmart and close to dining options. Packed with kid-friendly amenities...
United States
Henry S.
$409 nightly
The price is $434
Dec 1 - Dec 2
Total with taxes and fees
Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

Vacation Home in Santa Isabel

8.8 out of 10, Excellent, (44)
"It was amazing to be in the center of the culture. Friendly neighbors! Food amazing! Beach’s all around I would definitely stay there again!!!"
United States
Claudine N.
$343 nightly
The price is $364
Dec 1 - Dec 2
Total with taxes and fees
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Vacation Home in Santa Isabel

$320 nightly
The price is $340
Dec 1 - Dec 2
Total with taxes and fees
Coming and enjoy panoramic views to mountains and sea in Santa Isabel

Vacation Home in Salinas

10.0 out of 10, Exceptional, (2)
"Felt like home beautiful super clean quiet I will definitely be back to this home in our vacations Host is amazing Thank You for sharing this beautiful house with my family "
United States
julio
$159 nightly
The price is $169
Dec 1 - Dec 2
Total with taxes and fees
Trinitarias Guest's House's pool/bar/karaoke/wifi

Vacation Home in Cidra

10.0 out of 10, Exceptional, (2)
"The location was amazing "
United States
Maria
$179 nightly
The price is $190
Dec 8 - Dec 9
Total with taxes and fees
LA CASITA DEL LAGO

Vacation Home in Cidra

10.0 out of 10, Exceptional, (3)
"We have a wonderful time! The pool and bar were perfect!"
United States
Anna D.
$240 nightly
The price is $254
Dec 2 - Dec 3
Total with taxes and fees
Cozy studio with private Pool and Bar modern amentities perfect for relaxation.

Vacation Home in Salinas

9.8 out of 10, Exceptional, (21)
"The description of the house is accurate and the cleanliness of the rental was perfect. The neighborhood was amazing with restaurants and access to the water within walking distance. "
United States
Melanie D.
$150 nightly
The price is $159
Dec 1 - Dec 2
Total with taxes and fees
A cozy place to stay walking distance from the beach and Restaurants.

Vacation Home in Salinas

7.8 out of 10, Good, (13)
"Excellent place to stay near everything in town "
United States
Mayra
$130 nightly
The price is $138
Dec 2 - Dec 3
Total with taxes and fees
Oasis Salinas

Vacation Home in Cidra

10.0 out of 10, Exceptional, (2)
"Beautiful area, great AC, clean hot tub, lovely acces to lake with paddleboat!"
United States
Elizabeth C.
$177 nightly
The price is $188
Dec 1 - Dec 2
Total with taxes and fees
HW Tiny Home Cidra

Vacation Home in Cidra

9.4 out of 10, Exceptional, (6)
"We had a great peaceful visit!"
United States
Kelly N.
$105 nightly
The price is $111
Dec 1 - Dec 2
Total with taxes and fees
Grandpa's lake house lake private access mountain view museum 1950's experience

Vacation Home in Coamo

2.0 star property
$126 nightly
The price is $133
Dec 1 - Dec 2
Total with taxes and fees
Enjoyable 2nd story, 3-bedroom house with AC in Coamo, PR

Vacation Home in Guayama

10.0 out of 10, Exceptional, (2)
"Property was so beautiful didn’t have any complains. Everything you need in one spot you’d never want to leave."
United States
Jonathan
$177 nightly
The price is $188
Dec 1 - Dec 2
Total with taxes and fees
Cozy cabin with hot water jacuzzi and AC in the mountains of Guayama.

Vacation Home in Coamo

2.0 star property
10.0 out of 10, Exceptional, (1)
"Everything was very clean and organized I got confused with the address and the owner communicated with me and directed me to the exact address when I go to Puerto Rico again I will contact them again to stay at the same place "
United States
Carlos Reyes
$126 nightly
The price is $132
Dec 5 - Dec 6
Total with taxes and fees
Nostra Casa Vagón

Vacation Home in San Ildefonso

10.0 out of 10, Exceptional, (2)
"Our host was very accommodating. We enjoyed all of the games the house had to offer. The home was beautiful and private. We would stay again!"
United States
Katherine T.
$248 nightly
The price is $263
Dec 9 - Dec 10
Total with taxes and fees
Anime Escape with Private Jacuzzi & Themed Rooms

Vacation Home in Coamo

5.4 out of 10, (3)
"The house was nice ,comfortable and community was quiet and safe. we will be back..."
United States
Kenny R.
$111 nightly
The price is $117
Dec 1 - Dec 2
Total with taxes and fees
3-bedroom house in Coamo with AC on bedroom 1

Vacation Home in Ponce

10.0 out of 10, Exceptional, (1)
"This property was convenient, super clean and had everything that we needed! "
United States
Heather L.
$199 nightly
The price is $211
Dec 9 - Dec 10
Total with taxes and fees
Spacious Retreat with Private Jacuzzi and Tropical Patio

Vacation Home in Coamo

2.0 star property
$325 nightly
The price is $325
Dec 2 - Dec 3
Total with taxes and fees
Campo 5 Retreat W/ Private Climatized Pool

Vacation Home in Ponce

$333 nightly
The price is $354
Dec 1 - Dec 2
Total with taxes and fees
Retro Resort-Style Home w/ Pool, Theater, Game Room, Mini Golf and & More

Vacation Home in Ponce

$303 nightly
The price is $322
Dec 8 - Dec 9
Total with taxes and fees
Expansive Paradise with Private Jacuzzi and Tropical Patio

Vacation Home in Ponce

10.0 out of 10, Exceptional, (1)
"The apartments were ideal for a large group of older adults. There were plenty of comfortable beds and the kitchen was good to work out of for group meals. Armando was very responsive when we had some minor issues. The location was great. The solar hot water was sometimes luke warm, but our volunteers were hot from working on repairing homes, so it wasn't a big problem. The two porches off Units 3 and 4 were a nice gathering place for a large group."
United States
Richard G.
$1,237 nightly
The price is $1,313
Dec 2 - Dec 3
Total with taxes and fees
Big House with 7 Private Apts, 10 Rooms & 17 beds
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Black Friday Sale

Limited-time deals: Save up to 50% on select hotels.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Isabel Hotel Reviews

Find out more about Santa Isabel

Santa Isabel Vacation Homes information

Number of reviews
99
Accommodation
106 Vacation Homes
Lowest Price
$111
Highest Price
$1,313

Explore a world of travel with Expedia