A calm lake with mountains in the background.

Agritourism Seneca Hotels

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

Next weekend
Sep 18 - Sep 20
In two weeks
Sep 25 - Sep 27
In one month
Oct 9 - Oct 11
In two months
Nov 6 - Nov 8
No exact matches found, but these alternatives could be just right

Recommended hotels in Seneca

A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.

1. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (888 reviews)
"Pleased with the entire experience!"
United States
Curtis
$114 nightly
The price is $125
Sep 27 - Sep 28
Total with taxes and fees
Tru by Hilton Seneca Clemson
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.

2. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (743 reviews)
"Great stay"
United States
kendra
$121 nightly
The price is $134
Oct 4 - Oct 5
Total with taxes and fees
Hampton Inn & Suites Seneca-Clemson Area
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

3. Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,017 reviews)
"Loved everything while there. We always look stay here"
United States
Christopher
$123 nightly
The price is $135
Sep 13 - Sep 14
Total with taxes and fees
Lakeside Lodge Clemson
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

4. Quality Inn Seneca US-123

Quality Inn Seneca US-123
2.5 star property
Seneca
8.0 out of 10, Very Good, (749 reviews)
"Every thing was good"
United States
Robert
$82 nightly
The price is $89
Sep 20 - Sep 21
Total with taxes and fees
Quality Inn Seneca US-123
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.

5. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.4 out of 10, Exceptional, (270 reviews)
"The rooms were very clean and comfortable. Breakfast was outstanding good selection. I love the tranquility of this hotel."
United States
Angela
$120 nightly
The price is $132
Sep 27 - Sep 28
Total with taxes and fees
Fairfield Inn & Suites Seneca Clemson Univ Area
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

6. Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very Good, (685 reviews)
"Friendly staff, comfortable bed"
United States
Michelle
$97 nightly
The price is $107
Sep 14 - Sep 15
Total with taxes and fees
Best Western Seneca-Clemson
A cabin with a large window, surrounded by trees.

7. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (102 reviews)
"Me and my family had a great time"
United States
Nirumol
$133 nightly
The price is $146
Sep 14 - Sep 15
Total with taxes and fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A Days Inn by Wyndham at dusk with a green roof, purple lighting, and a parking lot.

8. Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (783 reviews)
"Staff were nice and accommodating"
United States
Rosario
$80 nightly
The price is $88
Sep 13 - Sep 14
Total with taxes and fees
Days Inn by Wyndham Seneca / Clemson Area
A hallway with a wooden floor, a large mirror, and framed pictures on the walls.

9. Boutique hotel in historic downtown Seneca. Room #5, two King beds.

Boutique hotel in historic downtown Seneca. Room #5, two King beds.
Downtown
9.4 out of 10, Exceptional, (19 reviews)
"Great place to stay in Seneca. Very clean, comfortable beds, great location. Will definitely stay again!"
United States
Joseph K.
$188 nightly
The price is $204
Sep 14 - Sep 15
Total with taxes and fees
Boutique hotel in historic downtown Seneca. Room #5, two King beds.
A hallway with a wooden floor, a large mirror, and framed pictures on the walls.

10. Private Room #3

Private Room #3
Downtown
9.2 out of 10, Wonderful, (17 reviews)
"A hidden gem!"
United States
Jennifer R.
$188 nightly
The price is $204
Sep 14 - Sep 15
Total with taxes and fees
Private Room #3
A hallway with a wooden floor, a large mirror, and framed pictures on the walls.

11. Boutique hotel in historic downtown Seneca. Room #4, King bed.

Boutique hotel in historic downtown Seneca. Room #4, King bed.
Downtown
9.2 out of 10, Wonderful, (27 reviews)
"Great location and great price."
United States
Julie C.
$188 nightly
The price is $204
Sep 14 - Sep 15
Total with taxes and fees
Boutique hotel in historic downtown Seneca. Room #4, King bed.
A hallway with a wooden floor, a large mirror, and framed pictures on the walls.

12. Boutique hotel in historic downtown Seneca. Room #6, King Bed.

Boutique hotel in historic downtown Seneca. Room #6, King Bed.
Downtown
9.0 out of 10, Wonderful, (32 reviews)
"We have stayed here several times. Another great experience!"
United States
Ali R.
$188 nightly
The price is $204
Sep 13 - Sep 14
Total with taxes and fees
Boutique hotel in historic downtown Seneca. Room #6, King Bed.
A blue building with a wooden deck and two Adirondack chairs.

13. Cozy Clemson TIny House Cabin

Cozy Clemson TIny House Cabin
Seneca
10.0 out of 10, Exceptional, (3 reviews)
"The property was very clean and well maintained. The living space is large and the bathroom quite large as well. It was perfect for our needs. It is close to everything in the area. Jim was extremely helpful and super quick with his responses to our questions."
United States
Peter M.
$198 nightly
The price is $218
Sep 15 - Sep 16
Total with taxes and fees
Cozy Clemson TIny House Cabin
A RV with a covered patio area, outdoor seating, and a grill.

14. Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
Seneca
10.0 out of 10, Exceptional, (15 reviews)
"Perfect pet friendly spot to enjoy a weekend getaway! Quiet campground, homey vibe, and awesome location!"
United States
Josie G.
$183 nightly
The price is $201
Sep 14 - Sep 15
Total with taxes and fees
Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
A covered outdoor area with a wooden structure, a gravel path, and a white RV labeled 'Wilderness' in the background.

15. Camping on Fancy-Perfect for small family getaway or couples retreat!

Camping on Fancy-Perfect for small family getaway or couples retreat!
Seneca
$160 nightly
The price is $176
Sep 14 - Sep 15
Total with taxes and fees
Camping on Fancy-Perfect for small family getaway or couples retreat!
A bedroom with a bed, a television, a clock, a dresser, and a bathroom visible through an open door.

16. Peaceful 3-bedroom home 4 miles from Clemson.

Peaceful 3-bedroom home 4 miles from Clemson.
Seneca
$267 nightly
The price is $294
Sep 15 - Sep 16
Total with taxes and fees
Peaceful 3-bedroom home 4 miles from Clemson.
A single-story house with a front porch, a small garden, and a clear sky.

17. Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Downtown
10.0 out of 10, Exceptional, (22 reviews)
"Great host! We had a great experience during our stay. "
United States
David E.
$347 nightly
The price is $381
Sep 13 - Sep 14
Total with taxes and fees
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
A two-story house with a front porch, a red door, and a well-maintained lawn.

18. Walk to Boat Ramp Lake Keowee w/ Parking + Firepit

Walk to Boat Ramp Lake Keowee w/ Parking + Firepit
Seneca
$375 nightly
The price is $393
Sep 14 - Sep 15
Total with taxes and fees
Walk to Boat Ramp Lake Keowee w/ Parking + Firepit
A single-story house with a garage, a chimney, and an air conditioning unit.

19. Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University

Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University
Seneca
10.0 out of 10, Exceptional, (1 review)
"Beautiful home, no complaints."
United States
Brenda
$296 nightly
The price is $326
Sep 13 - Sep 14
Total with taxes and fees
Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Seneca Hotel Reviews

Lakeside Lodge Clemson

Lakeside Lodge Clemson

10/10 Excellent
"Always amazing"
Charles 2-night trip
Posted 9 hours ago
Lakeside Lodge Clemson

Find out more about Seneca

Seneca Farmstay information

Number of reviews
4,630
Accommodation
2 Farmstay
Lowest Price
$88
Highest Price
$393

Explore a world of travel with Expedia