Title: Seneca, SC Guest Houses from $76 | Expedia.com

[Seneca Travel Guide](https://expedia.com/Seneca.dx6548)[Hotels in Seneca](https://expedia.com/Seneca-Hotels.d6548.Travel-Guide-Hotels)[Vacation Rentals in Seneca](https://expedia.com/Seneca-Vacation-Rentals.d6548.Travel-Guide-VacationRentals)[Flights to Seneca](https://expedia.com/Cheap-Flights-To-Seneca.d6548.Travel-Guide-Flights)[Car Rentals in Seneca](https://expedia.com/Car-Rentals-In-Seneca.d6548.Car-Rental-Guide)[Seneca Vacation Packages](https://expedia.com/Seneca.d6548.Destination-Travel-Guides)

![Lake Keowee South Carolina](https://images.trvl-media.com/place/6548/8356140f-bae9-4afc-8d65-c18efc5581aa.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6548/8356140f-bae9-4afc-8d65-c18efc5581aa.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

Next weekend

[Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=6548&startDate=2026-02-13&endDate=2026-02-15&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=6548&startDate=2026-02-20&endDate=2026-02-22&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In one month

[Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=6548&startDate=2026-03-06&endDate=2026-03-08&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6548&startDate=2026-04-03&endDate=2026-04-05&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

No exact matches found, but these alternatives could be just right

## Recommended hotels in Seneca

![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/db449d90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/ad742419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/6abd26aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/91e6d418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lakeside Lodge Clemson

[](https://www.expedia.com/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information)

Seneca

9.0/10

Wonderful

(1,000 reviews)

"Great place to stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gene

$123 nightly

$135 total

Feb 7 - Feb 8

Total with taxes and fees

[](https://www.expedia.com/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/81c4f249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/f6f7c8c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business center](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/16b3def6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Seneca Clemson Area US-123

[](https://www.expedia.com/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information)

Downtown

8.0/10

Very Good

(673 reviews)

"Our stay was very nice. Clean room. The outside was clean. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gayle

$84 nightly

$92 total

Feb 14 - Feb 15

Total with taxes and fees

[](https://www.expedia.com/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/w4000h2662x0y0-18bf21d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/2c84c92f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/e45ab30f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/cc35e730.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites Seneca Clemson Univ Area 

[](https://www.expedia.com/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information)

Seneca

9.4/10

Exceptional

(206 reviews)

"Spotless, friendly staff, great location. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cari

$125 nightly

$138 total

Feb 10 - Feb 11

Total with taxes and fees

[](https://www.expedia.com/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/8f736b3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/313b57b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/1436aba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/aca2d330.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Seneca-Clemson Area

[](https://www.expedia.com/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information)

Seneca

9.2/10

Wonderful

(676 reviews)

"Everything was excellent "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Debby

$119 nightly

$131 total

Feb 8 - Feb 9

Total with taxes and fees

[](https://www.expedia.com/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/d7c06df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/cf119645.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/ec2a8fca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Queen Bed (View) | Private kitchen | Mini-fridge, stovetop, cookware/dishes/utensils, paper towels](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/60991646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

[](https://www.expedia.com/Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information)

Seneca

9.8/10

Exceptional

(57 reviews)

"Excellent stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Beonca

$129 nightly

$142 total

Feb 8 - Feb 9

Total with taxes and fees

[](https://www.expedia.com/Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/83732283.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds | Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/62fa3a56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/b202edd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/590fd43d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tru by Hilton Seneca Clemson

[](https://www.expedia.com/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information)

Seneca

9.2/10

Wonderful

(805 reviews)

"Perfect stay for a weekend. Lots of shopping and restaurants nearby. Clean safe area annd the staff was wonderful!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cindy

$109 nightly

$120 total

Feb 17 - Feb 18

Total with taxes and fees

[](https://www.expedia.com/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information)

![Standard Room, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/eaa8fc9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/65f927f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/83901eb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/d223eeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Seneca-Clemson

[](https://www.expedia.com/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information)

Seneca

8.4/10

Very Good

(646 reviews)

"The stay was amazing "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tabatha

$98 nightly

$108 total

Feb 12 - Feb 13

Total with taxes and fees

[](https://www.expedia.com/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96690000/96684200/96684171/e82aa6e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/97000000/96690000/96684200/96684171/72eb904e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/97000000/96690000/96684200/96684171/7d406dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/97000000/96690000/96684200/96684171/811b8849.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Boutique hotel in historic downtown Seneca. Room #5, two King beds.

[](https://www.expedia.com/Seneca-Hotels-Boutique-Hotel-In-Historic-Downtown-Seneca-Room-5.h96684171.Hotel-Information)

Downtown

9.6/10

Exceptional

(15 reviews)

"We had a wonderful visit- clean and beautifully decorated. It was a little bit unusual to not have a window but very nice stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rachel L.

$181 nightly

$196 total

Feb 8 - Feb 9

Total with taxes and fees

[](https://www.expedia.com/Seneca-Hotels-Boutique-Hotel-In-Historic-Downtown-Seneca-Room-5.h96684171.Hotel-Information)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96690000/96683400/96683303/w1290h849x0y0-46041109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/97000000/96690000/96683400/96683303/cf717f09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/97000000/96690000/96683400/96683303/58429ce4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/97000000/96690000/96683400/96683303/8ce3646a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Boutique hotel in historic downtown Seneca. Room #4, King bed.

[](https://www.expedia.com/Seneca-Hotels-Boutique-Hotel-In-Historic-Downtown-Seneca-Room-4.h96683303.Hotel-Information)

Downtown

9.6/10

Exceptional

(18 reviews)

"Great spot! Have stayed several different times and always come back!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ashleigh G.

$183 nightly

$199 total

Feb 8 - Feb 9

Total with taxes and fees

[](https://www.expedia.com/Seneca-Hotels-Boutique-Hotel-In-Historic-Downtown-Seneca-Room-4.h96683303.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/51000000/50270000/50261400/50261396/fc19a084.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/51000000/50270000/50261400/50261396/84e2f8d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/51000000/50270000/50261400/50261396/64f3f98d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/51000000/50270000/50261400/50261396/6f1e18f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tucker Farm Cottage on Century Farm

[](https://www.expedia.com/Seneca-Hotels-Tucker-Farm-Cottage-On-Century-Farm.h50261396.Hotel-Information)

Seneca

10/10

Exceptional

(33 reviews)

"Excellent stay, beautiful area!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Barbara W.

$368 nightly

$388 total

Feb 7 - Feb 8

Total with taxes and fees

[](https://www.expedia.com/Seneca-Hotels-Tucker-Farm-Cottage-On-Century-Farm.h50261396.Hotel-Information)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/c0b82041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/c2f5c321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/5fc6414e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/f26a8dd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

###  Enjoy one of our RV units son less of a headache for you this vacation!

[](https://www.expedia.com/Seneca-Hotels-Cozy-Campground-In-Enchanting-Seneca-With-AC.h117644416.Hotel-Information)

Seneca

8.0/10

Very Good

(4 reviews)

"My partner and I stayed 5 nights and we enjoyed it so much. It's such a convenient place to reside for a get away. If you're looking for that "outback" feeling but want to be cozy; look no further. Communication was always qick with responses and was more than willing to help with anything we needed! We would definitely stay again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Denise s.

$139 nightly

$153 total

Mar 1 - Mar 2

Total with taxes and fees

[](https://www.expedia.com/Seneca-Hotels-Cozy-Campground-In-Enchanting-Seneca-With-AC.h117644416.Hotel-Information)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96690000/96683100/96683053/w1290h856x0y0-3209f519.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/97000000/96690000/96683100/96683053/1cece012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/97000000/96690000/96683100/96683053/480b48c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/97000000/96690000/96683100/96683053/783bd314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Private Room #3

[](https://www.expedia.com/Seneca-Hotels-Private-Room-3.h96683053.Hotel-Information)

Downtown

9.2/10

Wonderful

(13 reviews)

"Very clean and comfortable! Will stay again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joseph K.

$181 nightly

$196 total

Feb 8 - Feb 9

Total with taxes and fees

[](https://www.expedia.com/Seneca-Hotels-Private-Room-3.h96683053.Hotel-Information)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/56ab80ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/72b1141f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/dac98c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/79b68f69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn by Wyndham Seneca / Clemson Area

[](https://www.expedia.com/Anderson-Hotels-Days-Inn-By-Wyndham-Seneca-Clemson-Area.h14854.Hotel-Information)

Seneca

6.8/10

(725 reviews)

"Room was clean. Quiet place to rest. Lisa at the front desk was very helpful and very nice. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Teresa

$69 nightly

$76 total

Feb 8 - Feb 9

Total with taxes and fees

[](https://www.expedia.com/Anderson-Hotels-Days-Inn-By-Wyndham-Seneca-Clemson-Area.h14854.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/w1536h2048x0y0-6998e207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/405dd7c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/511c9b4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/c9812bb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Clemson TIny House Cabin

[](https://www.expedia.com/Seneca-Hotels-Cozy-Clemson-TIny-House-Cabin.h122332322.Hotel-Information)

Seneca

$200 nightly

$220 total

Feb 8 - Feb 9

Total with taxes and fees

[](https://www.expedia.com/Seneca-Hotels-Cozy-Clemson-TIny-House-Cabin.h122332322.Hotel-Information)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96690000/96684400/96684378/w1290h856x0y0-36eb931e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/97000000/96690000/96684400/96684378/0ea4c48a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/97000000/96690000/96684400/96684378/230e4003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/97000000/96690000/96684400/96684378/94a7d324.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Boutique hotel in historic downtown Seneca. Room #6, King Bed.

[](https://www.expedia.com/Seneca-Hotels-Boutique-Hotel-In-Historic-Downtown-Seneca-Room-6.h96684378.Hotel-Information)

Downtown

9.2/10

Wonderful

(24 reviews)

"Great stay. Super cute decor. Loved the location. Will be staying again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

denise n.

$183 nightly

$199 total

Feb 8 - Feb 9

Total with taxes and fees

[](https://www.expedia.com/Seneca-Hotels-Boutique-Hotel-In-Historic-Downtown-Seneca-Room-6.h96684378.Hotel-Information)

![Private kitchen](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/40d3b059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/1da4db10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/ec808a43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/45872750.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Clemson Cottage - 3.6 mi. to Memorial Stadium

[](https://www.expedia.com/Seneca-Hotels-The-Clemson-Cottage-36-Mi-To-Memorial-Stadium.h96153668.Hotel-Information)

Seneca

10/10

Exceptional

(12 reviews)

"Adorable and clean home convenient to Clemson’s campus. We enjoyed our stay and Tyler was an exceptional host! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mandy H.

$360 nightly

$396 total

Feb 8 - Feb 9

Total with taxes and fees

[](https://www.expedia.com/Seneca-Hotels-The-Clemson-Cottage-36-Mi-To-Memorial-Stadium.h96153668.Hotel-Information)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/67979a9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/c5a2afe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/4513793e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/e2588273.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

[](https://www.expedia.com/Seneca-Hotels-Cozy-Camper-In-Clemson-Hills-5-Minutes-From-Clemson-University-Pet-Friendly.h100784243.Hotel-Information)

Seneca

10/10

Exceptional

(12 reviews)

"Very clean and comfortable - very close to Clemson and easy access. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jim A.

$183 nightly

$201 total

Feb 9 - Feb 10

Total with taxes and fees

[](https://www.expedia.com/Seneca-Hotels-Cozy-Camper-In-Clemson-Hills-5-Minutes-From-Clemson-University-Pet-Friendly.h100784243.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/0834ba3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/c941d493.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/51bdec15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/ab96edf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

[](https://www.expedia.com/Seneca-Hotels-Lakefront-Tiny-Home-Retreat-On-Hartwell-Near-CU.h120082534.Hotel-Information)

Seneca

8.6/10

Excellent

(4 reviews)

"Everything was in great condition! Items provided were good quality. You can tell a lot of time and thought has been put into this property. We would love to stay again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alisa W.

$265 nightly

$292 total

Feb 8 - Feb 9

Total with taxes and fees

[](https://www.expedia.com/Seneca-Hotels-Lakefront-Tiny-Home-Retreat-On-Hartwell-Near-CU.h120082534.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/7bfcd263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/fa054611.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/8d32bcc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, table tennis](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/1692b12e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 3-bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

[](https://www.expedia.com/Seneca-Hotels-3-Bedroom-2-Bath-Home-Located-Minutes-From-Keowee-Mariana.h118704946.Hotel-Information)

Seneca

10/10

Exceptional

(5 reviews)

"Great place with a lot close by"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Aldor D.

$289 nightly

$317 total

Feb 8 - Feb 9

Total with taxes and fees

[](https://www.expedia.com/Seneca-Hotels-3-Bedroom-2-Bath-Home-Located-Minutes-From-Keowee-Mariana.h118704946.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/e032590e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cookware/dishes/utensils, paper towels](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/bc9bfba2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/9b29fdfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/8a811318.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming 3-bedroom house with WiFi and AC in serene Seneca on Lake Hartwell

[](https://www.expedia.com/Charming-3-Bedroom-House-With-WiFi-And-AC-In-Serene-Seneca-On-Lake-Hartwell.h114542071.Hotel-Information)

Seneca

10/10

Exceptional

(9 reviews)

"We enjoyed our stay. Had everything we needed. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Diane S.

$480 nightly

$528 total

Feb 7 - Feb 8

Total with taxes and fees

[](https://www.expedia.com/Charming-3-Bedroom-House-With-WiFi-And-AC-In-Serene-Seneca-On-Lake-Hartwell.h114542071.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Seneca Hotel Reviews

![Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/8c11b789_y.jpg)

### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

10/10 Excellent

"Very clean! Cozy space. Great 24 hour getaway! "

[](https://expedia.com/Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information)

![Hampton Inn & Suites Seneca-Clemson Area](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/1436aba9_y.jpg)

### Hampton Inn & Suites Seneca-Clemson Area

10/10 Excellent

"Woman at the front desk "

[](https://expedia.com/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information)

![Lakeside Lodge Clemson](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/9732d3ff_y.jpg)

### Lakeside Lodge Clemson

10/10 Excellent

"Spotless room, great staff, and amenities"

[](https://expedia.com/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information)

![5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!](https://images.trvl-media.com/lodging/62000000/61020000/61010400/61010330/fa789e5c_y.jpg)

### 5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!

10/10 Excellent

"What a wonderful place for our family gathering. The large commons area provided beautiful views of the lake. There were a variety of places to play games and enjoy our time together."

[](https://expedia.com/Seneca-Hotels-Modern-Lakefront-Luxury-Oasis-270-Lake-Views-WDock.h61010330.Hotel-Information)

![Quality Inn Seneca Clemson Area US-123](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2_y.jpg)

### Quality Inn Seneca Clemson Area US-123

10/10 Excellent

"Our stay was very nice. Clean room. The outside was clean. "

[](https://expedia.com/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information)

![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg)

### Best Western Plus Clemson Hotel & Conference Center

10/10 Excellent

"Rooms are clean. Staff was very pleasant. "

[](https://expedia.com/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information)

![Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock](https://images.trvl-media.com/lodging/28000000/27120000/27118400/27118346/67cc829e_y.jpg)

### Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock

10/10 Excellent

"We will definitely be booking this property again. We usually have family gathering inJanuary and I think this will be our new location. It accommodated those lodging with us and who came to visit while we were there. The flow of the house and outdoors was so convenient especially for our large gathering when we roasted oysters. "

[](https://expedia.com/Seneca-Hotels-Quiet-Cove.h27118346.Hotel-Information)

![Fairfield Inn & Suites Seneca Clemson Univ Area    ](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/9fe06894_y.jpg)

### Fairfield Inn & Suites Seneca Clemson Univ Area 

10/10 Excellent

"Spotless, friendly staff, great location. "

[](https://expedia.com/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information)

![Tru by Hilton Seneca Clemson](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/10f1fcf8_y.jpg)

### Tru by Hilton Seneca Clemson

10/10 Excellent

"The staff here are top tier! We had to be at a meet at the university by 6am and they made breakfast early so our kids could eat before the meet! Genuine care for their guest! Love it here! "

[](https://expedia.com/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information)

## Find out more about Seneca

## Seneca Guest Houses information

| Number of reviews | 4,935          |
| ----------------- | -------------- |
| Accommodation     | 3 Guest Houses |
| Lowest Price      | $76            |
| Highest Price     | $528           |

## Frequently asked questions

### What is the nightly rate for a guest house in Seneca?

### What's the difference between a Seneca guest house and a B&B?

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- [Flights from Toledo (TOL) to Clemson (CEU) ](https://www.expedia.com/lp/flights/tol/ceu/toledo-to-clemson)
- [Flights from Wilkes-Barre (AVP) to Clemson (CEU) ](https://www.expedia.com/lp/flights/avp/ceu/wilkes-barre-to-clemson)
- [Flights from Oakland (OAK) to Clemson (CEU) ](https://www.expedia.com/lp/flights/oak/ceu/oakland-to-clemson)
- [Flights from Orlando (SFB) to Clemson (CEU) ](https://www.expedia.com/lp/flights/sfb/ceu/orlando-to-clemson)
- [Flights from New York (NYC) to Clemson (CEU) ](https://www.expedia.com/lp/flights/nyc/ceu/new-york-to-clemson)
- [Flights from Binghamton (BGM) to Clemson (CEU) ](https://www.expedia.com/lp/flights/bgm/ceu/binghamton-to-clemson)
- [Flights from Mexico City (MEX) to Clemson (CEU) ](https://www.expedia.com/lp/flights/mex/ceu/mexico-city-to-clemson)
- [Flights from San Juan (SJU) to Clemson (CEU) ](https://www.expedia.com/lp/flights/sju/ceu/san-juan-to-clemson)
- [Flights from Gatlinburg (GKT) to Clemson (CEU) ](https://www.expedia.com/lp/flights/gkt/ceu/gatlinburg-to-clemson)
- [Flights from Panama City (PTY) to Clemson (CEU) ](https://www.expedia.com/lp/flights/pty/ceu/panama-city-to-clemson)
- [Flights from Fresno (FAT) to Clemson (CEU) ](https://www.expedia.com/lp/flights/fat/ceu/fresno-to-clemson)
- [Flights from Colorado Springs (COS) to Clemson (CEU) ](https://www.expedia.com/lp/flights/cos/ceu/colorado-springs-to-clemson)
- [Flights from Moline (MLI) to Clemson (CEU) ](https://www.expedia.com/lp/flights/mli/ceu/moline-to-clemson)
- [Flights from Tokyo (TYO) to Clemson (CEU) ](https://www.expedia.com/lp/flights/tyo/ceu/tokyo-to-clemson)
- [Flights from Sacramento (SMF) to Clemson (CEU) ](https://www.expedia.com/lp/flights/smf/ceu/sacramento-to-clemson)
- [Flights from Anderson (AND) to Clemson (CEU) ](https://www.expedia.com/lp/flights/and/ceu/anderson-to-clemson)
- [Flights from Houston (IAH) to Clemson (CEU) ](https://www.expedia.com/lp/flights/iah/ceu/houston-to-clemson)
- [Flights from Frankfurt (FRA) to Clemson (CEU) ](https://www.expedia.com/lp/flights/fra/ceu/frankfurt-to-clemson)
- [Flights from Copenhagen (CPH) to Clemson (CEU) ](https://www.expedia.com/lp/flights/cph/ceu/copenhagen-to-clemson)
- [Flights from Manchester (MAN) to Clemson (CEU) ](https://www.expedia.com/lp/flights/man/ceu/manchester-to-clemson)

- [Littlejohn Coliseum ](https://www.expedia.com/Littlejohn-Coliseum-Clemson.d6228662.Vacation-Attraction)

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