Photo by Cindy Keese

Search Guest Houses in Seneca

Check prices for these dates

Next weekend
Aug 15 - Aug 17
In two weeks
Aug 22 - Aug 24
In one month
Sep 5 - Sep 7
In two months
Oct 3 - Oct 5

Guest Houses in Seneca

Chauga River - The Guest House - Private - Secluded
Relax in a serene riverside setting with two Adirondack chairs under a shelter.

Chauga River - The Guest House - Private - Secluded

10.0 out of 10, Exceptional, (90)
"The house was very clean and had everything we "
Chauga River - The Guest House - Private - Secluded
Peaceful Lakefront Getaway Close to Clemson
Enjoy a meal on the deck with a view of the lake and the surrounding cabin.

Peaceful Lakefront Getaway Close to Clemson

10.0 out of 10, Exceptional, (39)
"location was great, dock area a plus"
Peaceful Lakefront Getaway Close to Clemson
BEAUTIFUL GUEST HOUSE NEAR THE SMOKEY MOUNTAINS. PROPERY IS FOR VACATION.
Surrounded by lush greenery, this cabin features a wooden deck and outdoor seating area.

BEAUTIFUL GUEST HOUSE NEAR THE SMOKEY MOUNTAINS. PROPERY IS FOR VACATION.

10.0 out of 10, Exceptional, (21)
"We could not have asked for a better place to stay. Everything was clean and just as described in the listing. Sandi was the perfect host!"
BEAUTIFUL GUEST HOUSE NEAR THE SMOKEY MOUNTAINS. PROPERY IS FOR VACATION.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Seneca Hotel Reviews

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

10/10 Excellent
"The original room I got was not cleaned properly. The front dest staff Trinity took great care of me and rectified the issue swiftly and satisfactorily! New building is lovely. Room was spacious and clean. Well maintained and will stay here again. "
Hadiya 1-night trip
Posted 2 days ago
Days Inn by Wyndham Anderson

Frequently asked questions

What is the nightly rate for a guest house in Seneca?
Rates for Seneca guest houses vary, but travelers can find great-value prices with Expedia. A range of factors can affect nightly rates, such as the location, the breakfast offering, and the range of amenities. Travelers looking for a good deal should consider looking for a midweek stay, as weekend rates at Seneca guest houses tend to be higher. Remember to also use our filters to sort prices from low to high.
What's the difference between a Seneca guest house and a B&B?
A guest house in Seneca is typically a larger establishment with more rooms, offering a more hotel-like experience, and may provide additional amenities including luxury bedding. In contrast, a B&B is usually a smaller property that focuses primarily on providing a room and breakfast. A B&B is often more personal, and breakfast is typically included as part of the stay, but other services might be more limited compared to a guest house.