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Recommended hotels in Seneca

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (76 reviews)
"Awesome place "
United States
Jason
$139 nightly
The price is $153
Jun 7 - Jun 8
Total with taxes and fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very Good, (708 reviews)
"Clean room comfortable beds"
United States
Cheryl
$91 nightly
The price is $99
Jun 9 - Jun 10
Total with taxes and fees
Quality Inn Seneca Clemson Area US-123

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,006 reviews)
"Beautiful property and nice room."
United States
Lynzee
$123 nightly
The price is $135
Jun 7 - Jun 8
Total with taxes and fees
Lakeside Lodge Clemson

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.4 out of 10, Exceptional, (234 reviews)
"Excellent in every way … staff, room, amenities and very comfortable bed!"
United States
Sarah
$129 nightly
The price is $142
Jun 11 - Jun 12
Total with taxes and fees
Fairfield Inn & Suites Seneca Clemson Univ Area

Cozy Clemson TIny House Cabin

Cozy Clemson TIny House Cabin
Seneca
$196 nightly
The price is $216
Jun 7 - Jun 8
Total with taxes and fees
Cozy Clemson TIny House Cabin

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (845 reviews)
"Everything about this hotel was great the staff was very friendly rooms was very clean great location I highly suggest staying here"
United States
Jason
$106 nightly
The price is $116
Jul 1 - Jul 2
Total with taxes and fees
Tru by Hilton Seneca Clemson

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (752 reviews)
"Clean and comfortable "
United States
Robyn
$73 nightly
The price is $80
Jun 14 - Jun 15
Total with taxes and fees
Days Inn by Wyndham Seneca / Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (718 reviews)
"Nice staff, clean rooms, nice breakfast "
United States
Daren
$119 nightly
The price is $131
Jun 11 - Jun 12
Total with taxes and fees
Hampton Inn & Suites Seneca-Clemson Area

Boutique hotel in historic downtown Seneca. Room #6, King Bed.

Boutique hotel in historic downtown Seneca. Room #6, King Bed.
Downtown
9.2 out of 10, Wonderful, (25 reviews)
"Great stay. Super cute decor. Loved the location. Will be staying again. "
United States
denise n.
$190 nightly
The price is $206
Jun 7 - Jun 8
Total with taxes and fees
Boutique hotel in historic downtown Seneca. Room #6, King Bed.

Boutique hotel in historic downtown Seneca. Room #5, two King beds.

Boutique hotel in historic downtown Seneca. Room #5, two King beds.
Downtown
9.4 out of 10, Exceptional, (18 reviews)
"Great place to stay in Seneca. Very clean, comfortable beds, great location. Will definitely stay again!"
United States
Joseph K.
$188 nightly
The price is $204
Jun 8 - Jun 9
Total with taxes and fees
Boutique hotel in historic downtown Seneca. Room #5, two King beds.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very Good, (663 reviews)
"Friendly staff, comfortable bed"
United States
Michelle
$97 nightly
The price is $107
Jun 29 - Jun 30
Total with taxes and fees
Best Western Seneca-Clemson

Camping on Fancy-Perfect for small family getaway or couples retreat!

Camping on Fancy-Perfect for small family getaway or couples retreat!
Seneca
$152 nightly
The price is $167
Jun 8 - Jun 9
Total with taxes and fees
Camping on Fancy-Perfect for small family getaway or couples retreat!

Tucker Farm Cottage on Century Farm

Tucker Farm Cottage on Century Farm
Seneca
10.0 out of 10, Exceptional, (36 reviews)
"Excellent stay, beautiful area!"
United States
Barbara W.
$358 nightly
The price is $373
Jun 7 - Jun 8
Total with taxes and fees
Tucker Farm Cottage on Century Farm

Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
Seneca
10.0 out of 10, Exceptional, (13 reviews)
"Very clean and comfortable - very close to Clemson and easy access. "
United States
Jim A.
$183 nightly
The price is $201
Jun 8 - Jun 9
Total with taxes and fees
Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms

Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms
Seneca
10.0 out of 10, Exceptional, (24 reviews)
"Very nice accommodations and great location for stay in Clemson. "
United States
Marisa G.
$313 nightly
The price is $344
Jun 8 - Jun 9
Total with taxes and fees
Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms

Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University

Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University
Seneca
$291 nightly
The price is $320
Jun 7 - Jun 8
Total with taxes and fees
Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University

Private Room #3

Private Room #3
Downtown
9.0 out of 10, Wonderful, (15 reviews)
"Very clean and comfortable! Will stay again!"
United States
Joseph K.
$188 nightly
The price is $204
Jun 8 - Jun 9
Total with taxes and fees
Private Room #3

Boutique hotel in historic downtown Seneca. Room #4, King bed.

Boutique hotel in historic downtown Seneca. Room #4, King bed.
Downtown
9.6 out of 10, Exceptional, (21 reviews)
"Great location option for our visit to watch the Clemson game. Room was very comfortable with restaurant downstairs and fun brew pub nearby."
United States
Melissa T.
$188 nightly
The price is $204
Jun 11 - Jun 12
Total with taxes and fees
Boutique hotel in historic downtown Seneca. Room #4, King bed.

Waterfront 3br home on Lake Hartwell near Clemson

Waterfront 3br home on Lake Hartwell near Clemson
Seneca
10.0 out of 10, Exceptional, (11 reviews)
"We enjoyed our stay. Had everything we needed. "
United States
Diane S.
$479 nightly
The price is $527
Jun 7 - Jun 8
Total with taxes and fees
Waterfront 3br home on Lake Hartwell near Clemson

Carolina Cottage Retreat-12 Minutes from Clemson University

Carolina Cottage Retreat-12 Minutes from Clemson University
Seneca
$339 nightly
The price is $373
Jun 8 - Jun 9
Total with taxes and fees
Carolina Cottage Retreat-12 Minutes from Clemson University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Seneca Hotel Reviews

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Seneca Guest Houses information

Number of reviews
11,419
Accommodation
3 Guest Houses
Lowest Price
$60
Highest Price
$260

Frequently asked questions

What is the nightly rate for a guest house in Seneca?
Rates for Seneca guest houses vary, but travelers can find great-value prices from $60 with Expedia. A range of factors can affect nightly rates, such as the location, the breakfast offering, and the range of amenities. Travelers looking for a good deal should consider looking for a midweek stay, as weekend rates at Seneca guest houses tend to be higher. Remember to also use our filters to sort prices from low to high.
What's the difference between a Seneca guest house and a B&B?
A guest house in Seneca is typically a larger establishment with more rooms, offering a more hotel-like experience, and may provide additional amenities including luxury bedding. In contrast, a B&B is usually a smaller property that focuses primarily on providing a room and breakfast. A B&B is often more personal, and breakfast is typically included as part of the stay, but other services might be more limited compared to a guest house.

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