South San Francisco Vacations from $144

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Your South San Francisco Vacation

Lock in a South San Francisco vacation package and get ready to experience the best of this lively city. Consider basing yourself in the neighborhood of Sharp Park, which is great for families, nature and golfing. Make your trip to South San Francisco even more fun by including some sightseeing. San Francisco State University, Cow Palace and Pacifica State Beach are among the major attractions worth exploring. Browse Expedia's wide range of travel options and start organizing your ideal vacation to South San Francisco now.

The Latest South San Francisco vacation packages

Price found within the past 48 hours. Click for updated prices.
Cathedral Hill Hotel

Cathedral Hill Hotel

Downtown San Francisco
Save 100% on your flight
$144
per person
Dec 20 - Dec 22
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
7.2/10 Good! (741 reviews)
The front desk gentleman is so courteous, patient and helpful!! Honestly best hotel I've stayed at in SF

Reviewed on Oct 4, 2026

The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

Union Square
Save 100% on your flight
$537
per person
Nov 11 - Nov 14
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
8.8/10 Excellent! (2,195 reviews)
Location!

Reviewed on Oct 6, 2026

Cavallo Point

Cavallo Point

Save 100% on your flight
$1,553
per person
Dec 6 - Dec 12
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
9.2/10 Wonderful! (1,003 reviews)
Merritt House Hotel

Merritt House Hotel

Old Monterey
Save 100% on your flight
$984
per person
Dec 26 - Jan 2
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
9/10 Wonderful! (1,017 reviews)
Historic building in great location. Breakfast included. Walk to the waterfront, restaurants, and shopping. Very reasonable rates. Highly recommend.

Reviewed on Oct 5, 2026

@ Marbella Lane - 3BR W/sweeping Views of Bay Area

@ Marbella Lane - 3BR W/sweeping Views of Bay Area

South San Mateo
Save 100% on your flight
$3,619
per person
Dec 26 - Jan 2
found 14 hours ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
No reviews
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Stay near popular South San Francisco attractions

San Bruno Point Park

7.8/10 (451 reviews)
Point San Bruno Park offers panoramic views of San Francisco Bay and close-up aircraft sightings from nearby SFO. Stroll the waterfront trails and find a peaceful picnic spot away from the city's bustle.
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South San Francisco Convention Center

7.8/10 (668 reviews)
The South San Francisco Conference Center offers versatile meeting spaces with modern amenities near SFO airport. Business travelers appreciate its convenient location and comprehensive event services.
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San Francisco Baking Institute

7.6/10 (423 reviews)
Explore the campus of San Francisco Baking Institute during your visit to South San Francisco. Amble around this vibrant area's seaside and enjoy its top-notch restaurants.
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See's Candies

8.0/10 (474 reviews)
This American-made chocolate factory store welcomes visitors with the intoxicating aroma of fresh confections. Customize your own box of premium candies and savor the complimentary sample that greets every guest.
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South San Francisco Hillside Sign

You can find out about the history of South San Francisco with a stop at South San Francisco Hillside Sign.
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Sign Hill Park

Explore the great outdoors at Sign Hill Park, a lovely green space in South San Francisco. Check out the shops and top-notch restaurants in this family-friendly area.
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K1 Speed San Francisco

7.6/10 (330 reviews)
Race electric go-karts at top speeds on K1 Speed's professionally designed indoor track. For the ultimate experience, arrive on weekday afternoons when the track is less crowded.
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What to do in South San Francisco

Alcatraz Inside tour with Round trip ferry & Audio App Packages

Alcatraz Inside tour with Round trip ferry & Audio App Packages

$71
per adult
94% of travellers recommend
Alcatraz Inside tour with Round trip ferry & Audio App Packages
California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

$49
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
Alcatraz Visit with Night Option and SF Bay Cruise

Alcatraz Visit with Night Option and SF Bay Cruise

$139
per adult
94% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
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South San Francisco Hotel Deals

Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North

326 S Airport Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
$83 nightly
$98 total
Nov 5 - Nov 6
Total with taxes and fees
6/10 (4,151 reviews)
"X"

Reviewed on Oct 6, 2026

Travelodge by Wyndham San Francisco Airport North
DoubleTree by Hilton San Francisco South Airport Blvd

DoubleTree by Hilton San Francisco South Airport Blvd

275 S Airport Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
$130 nightly
$153 total
Nov 6 - Nov 7
Total with taxes and fees
8.4/10 Very Good! (2,452 reviews)
"The room were not cleaned with care"

Reviewed on Oct 6, 2026

DoubleTree by Hilton San Francisco South Airport Blvd
Park Pointe Hotel

Park Pointe Hotel

245 S Airport Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
$122 nightly
$143 total
Oct 7 - Oct 8
Total with taxes and fees
Park Pointe Hotel
See all 4,452 properties in South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best South San Francisco Vacation Packages

South San Francisco Essential Information

Language
English
Currency
U.S dollars
Closest Airport
San Francisco Intl. Airport (SFO)
Population
67,300
Max Temp Winter
60ºF
Max Temp Summer
70ºF
Top Sights
Ocean Beach, California Academy of Sciences and San Francisco Zoo

More vacations you might like

Frequently asked questions

What types of vacation packages are available in South San Francisco?
South San Francisco, known for its family-friendly attractions and urban appeal, offers vacation packages tailored to various travel styles:
  • Budget: For value-conscious travelers, properties like Park Pointe Hotel offer a comfortable stay with free breakfast and free WiFi, with travelers often noting its clean rooms and great value.
  • Family-Friendly: A package built around a stay at Home2 Suites by Hilton San Francisco Airport North, rated 8.6 out of 10 by travelers, provides amenities like a game room and kitchenettes, with guests praising its super clean rooms and nice staff.
  • Pet-Friendly: Many hotels welcome furry companions, such as La Quinta Inn & Suites by Wyndham San Francisco Airport N, rated 7.7 out of 10 by travelers, which features an outdoor pool and free breakfast, with guests highlighting its convenient location and clean rooms.
  • Convenience: Hotels offering practical amenities for a smooth trip include Embassy Suites by Hilton San Francisco Airport Oyster Point, a 3.5-star property rated 8.6 out of 10 by travelers, which provides free breakfast, an indoor pool, and family rooms, with guests praising the free breakfast and super comfortable rooms.
  • Couples: For a romantic getaway, consider a package with a stay at AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront, a 4-star hotel rated 8.4 out of 10 by travelers, featuring a bar/lounge and an indoor pool, with guests highlighting its amazing rooms and delicious breakfast.
How can I save money on a South San Francisco vacation package?
When you bundle, you can save up to 30%*. To save money on a South San Francisco package, consider traveling during the quieter months or be flexible with your dates to find more options. Bundling your flights and hotel together often unlocks savings compared to booking separately. *Members only. Savings vary.
How much does a South San Francisco vacation package cost?
A South San Francisco vacation package typically costs around $650 per adult for a weekend trip. Lower-priced bookings start from around $400 per adult, while packages with more luxurious accommodations can reach up to $1,450.*Package prices shown are the average total cost per adult across Expedia bookings over the past year and may change depending on availability, dates, and demand.
How do I find cheap South San Francisco vacation package deals?
The cheapest South San Francisco vacation package deals can be as low as around $350 per adult for weekend trips. Separately, December and November typically have the lowest average monthly prices, around $590 to $600 per adult, both for typical 2-day trips. Bundling flights and hotel together also typically saves money on a weekend trip — nearly all South San Francisco vacation package deals include some savings versus booking separately, typically around $30 per adult. Longer, two-week trips can save even more, often around $105 per adult. Many hotels in South San Francisco also offer free breakfast, which can help stretch your budget further. Browse cheap vacation packages in South San Francisco on Expedia for current deals.*Package prices shown are the average total cost per adult across Expedia bookings over the past year and may change depending on availability, dates, and demand.
What is the best time to go to South San Francisco?
The best time to go for a South San Francisco vacation package is during July and September, which are the peak months for demand. June also sees high booking activity, making these months popular for exploring the city and its attractions.For those seeking a more budget-friendly trip, December and November typically offer lower package prices. These quieter months can still be a good time to experience South San Francisco without the peak season crowds.
What's included in a South San Francisco vacation package?
A South San Francisco vacation package lets you combine round-trip flights, hotel stays, and rental cars. As a central urban destination, South San Francisco's many hotels offer convenient amenities. For instance, most hotels provide airport shuttle service to and from San Francisco International Airport (SFO), and many also include free breakfast, which can be a practical saving during your trip.Exactly what's included will vary by hotel and package, so it's worth reviewing the details before you confirm your booking.
What's the best vacation package for South San Francisco?
For families visiting South San Francisco, a package built around a stay at Home2 Suites by Hilton San Francisco Airport North is a strong choice. Rated 8.6 out of 10 by travelers, this hotel offers amenities like a game room and kitchenettes, with guests praising its super clean rooms and nice staff.Couples looking for a comfortable stay might consider a package with AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront. This 4-star property, rated 8.4 out of 10 by travelers, features a bar/lounge and an indoor pool, with travelers highlighting its amazing rooms and delicious breakfast.Travelers seeking good value can find excellent options like Park Pointe Hotel. This hotel provides free breakfast and free WiFi, and travelers often note its clean rooms and great value, making it a solid base for exploring the area.
Is South San Francisco better suited for a beach vacation or a cultural trip?
South San Francisco is primarily a central urban destination, offering a mix of city attractions, outdoor activities, and cultural points of interest. While a select few package hotels offer ocean views, it provides easy access to the wider San Francisco Bay Area.For cultural experiences, you can explore local history through the Linden Avenue Post Office's 1930s mural or the Grand Avenue Library's WPA art collection. Outdoor enthusiasts can hike Sign Hill, which offers trails and views, or visit Oyster Point Marina/Park along the San Francisco Bay. Your South San Francisco vacation can be tailored to explore these diverse aspects.
Is South San Francisco a good choice for a family vacation package?
South San Francisco is a strong choice for family vacation packages, with some of the bookings being family trips. Many hotels cater to families, offering amenities such as family rooms, free breakfast, and indoor or outdoor pools.For example, Embassy Suites by Hilton San Francisco Airport Oyster Point, a 3.5-star property rated 8.6 out of 10 by travelers, makes a comfortable base for families with its indoor pool and family rooms, and guests frequently praise the super comfortable rooms and always smiling staff.Families can explore Golden Gate Park, about 10 miles from central South San Francisco, which offers expansive green spaces and attractions. Locally, Orange Memorial Park provides children's play equipment, sports fields, and picnic grounds for outdoor fun.
What is the best time to book a South San Francisco vacation package?
Book your South San Francisco vacation package around 2 weeks in advance. This gives you time to secure your preferred flights and hotel while rates are still competitive. Most travelers book between 1 and 5 weeks out.May, June, and August are the most popular months for South San Francisco packages, so booking earlier is advisable if you're traveling during these times.
What are the top things to do in South San Francisco?
A South San Francisco vacation offers access to a variety of attractions, from local landmarks to iconic San Francisco sights:Browse and book things to do in South San Francisco on Expedia.
How many days do you need for a South San Francisco vacation?
Most South San Francisco vacation packages last around 3 days, with most travelers choosing weekend trips. This duration allows you to explore local attractions like the South San Francisco Convention Center and Cow Palace, or venture into San Francisco to see Golden Gate Park.Nearly a third of travelers opt for week-long trips, which provide more time to delve into the wider San Francisco Bay Area, including iconic sights like Golden Gate Bridge or Pier 39. A select few choose extended stays of around two weeks for a more in-depth exploration.
Is South San Francisco a good destination for a weekend vacation?
South San Francisco is a good destination for a weekend vacation package, with most travelers choosing weekend trips. A short trip allows you to focus on local attractions such as the South San Francisco Convention Center or the Cow Palace. You can also easily venture into San Francisco for a day to visit sights like Oracle Park or Chase Center.While many travelers opt for longer stays to explore the broader Bay Area, a South San Francisco vacation can be a focused and enjoyable weekend getaway.
Do you need to rent a car in South San Francisco, or is public transport enough?
For a South San Francisco vacation package, public transport can be sufficient for connecting to San Francisco and the airport, but a rental car offers more flexibility for exploring the wider Bay Area. The BART system provides rapid transit service to San Francisco International Airport (SFO) and downtown San Francisco, while Caltrain offers commuter rail service between San Francisco and San Jose.Additionally, local shuttle services are available, including a South City Shuttle connecting the South San Francisco BART station to the city's downtown, and shuttles to the Oyster Point office area and Ferry Terminal. However, with major freeways like U.S. Route 101 and Interstate 280 traversing the city, a car allows for easier access to attractions spread across the region and beyond.
Are South San Francisco vacation package hotels conveniently located?
South San Francisco vacation package hotels are generally conveniently located, with many properties within easy reach of the city center. For example, Embassy Suites by Hilton San Francisco Airport Oyster Point, a 3.5-star property rated 8.6 out of 10, is about a 5-minute walk from central South San Francisco.Other options like Home2 Suites by Hilton San Francisco Airport North, rated 8.6 out of 10, are about a 10-minute walk away. Even properties like AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront, a 4-star hotel rated 8.4 out of 10, are only about 1 mile from the city center, offering good access to local points of interest.
Are there vacation package hotels in South San Francisco within walking distance of restaurants and shops?
Central South San Francisco vacation package hotels often place you within walking distance of restaurants and shops. For instance, Embassy Suites by Hilton San Francisco Airport Oyster Point, a 3.5-star property rated 8.6 out of 10, is about a 5-minute walk from central South San Francisco, where you can find dining options along Grand Avenue.Similarly, Home2 Suites by Hilton San Francisco Airport North, rated 8.6 out of 10, and Airport Inn, rated 8.5 out of 10, are both about a 10-minute walk from the city center, providing easy access to local eateries and stores. Actual walking routes may vary, so it's always a good idea to check the map for your chosen hotel.
Can I change or cancel my South San Francisco vacation package if my plans change?
Yes, you can cancel your vacation package via your itinerary page on Expedia or by contacting customer service. Remember that some packages are fully refundable, but the details vary based on each unique booking. A fully refundable package may depend on how far out from the travel dates you're canceling and what airline you are traveling with.
Do One Key members get extra savings when booking South San Francisco vacation packages?
Yes, members who join our free One Key™ travel rewards program can instantly unlock additional savings and save 10% or more on over 500,000 stays worldwide with Member Prices and over 1 million car rentals.
Does Expedia offer Book Now, Pay Later South San Francisco vacation packages?
Yes, with Expedia's Book Now, Pay Later option, powered by Affirm, you can spread the cost of your South San Francisco vacation over 3, 6, or 12 months. With no late payment fees or hidden costs, it's easy to secure your ideal vacation package as soon as you spot it.
How do I find last-minute vacation packages to South San Francisco?
To find last-minute vacation packages to South San Francisco, explore the last-minute deals section for the latest package offers, including flights, departing in the coming weeks. Being flexible with your travel dates and hotel preferences can help you secure the best prices.
How does free cancellation work on South San Francisco vacation packages?
Free cancellation on a South San Francisco vacation package depends on the specific hotel and rate combination you book. Many bookings allow free cancellation up to a stated deadline (often a few days before travel) where eligible. Read the cancellation terms carefully when reviewing the package, and visit Expedia help center for further details.
Is it cheaper to book a South San Francisco vacation as a package or separately?
Booking flights and hotels together can unlock lower overall prices. Better still, you can tailor your South San Francisco getaway to match your exact preference. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
Why should I book my South San Francisco vacation package with Expedia?
Booking your vacation package on Expedia makes it easier to get more out of your trip from the start. With a wide choice of hotels, you can compare prices, reviews and amenities all in one place, then bundle your hotel with flights which could help you save even more. Flexible booking options on selected stays also make it easier to plan with confidence.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.