South San Francisco Vacations from $391

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Your South San Francisco Vacation

Lock in a South San Francisco vacation package and get ready to experience the best of this lively city. Consider basing yourself in the neighborhood of Sharp Park, which is great for families, nature and golfing. Make your trip to South San Francisco even more fun by including some sightseeing. San Francisco State University, Cow Palace and Pacifica State Beach are among the major attractions worth exploring. Browse Expedia's wide range of travel options and start organizing your ideal vacation to South San Francisco now.

The Latest South San Francisco vacation packages

Price found within the past 48 hours. Click for updated prices.
SOMA Park Inn – Civic Center

SOMA Park Inn – Civic Center

2 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $587, price is now $391 per person
$391
per person
Jun 5 - Jun 9
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
6.8/10 (1,000 reviews)
Nice place to stay. Very friendly staff.

Reviewed on Feb 1, 2026

Vinarosa Resort & Spa

Vinarosa Resort & Spa

4 out of 5
Save 100% on your flight
Price was $1,258, price is now $718 per person
$718
per person
Jul 10 - Jul 13
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
9.4/10 Exceptional! (841 reviews)
Such a beautiful hotel! The spa was relaxing, the grounds are beautiful, the food in the restaurant was amazing! Front desk couldn’t have been any kinder and accommodating! Our room was incredible, so spacious and just felt high end! Highly recommend, I will be back for sure!

Reviewed on Apr 16, 2026

Fairmont Heritage Place, Ghirardelli Square

Fairmont Heritage Place, Ghirardelli Square

5 out of 5
Fisherman's Wharf
Save 100% on your flight
Price was $6,184, price is now $3,921 per person
$3,921
per person
Jul 2 - Jul 7
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
9.4/10 Exceptional! (393 reviews)
Nothing but great things to say about this place! So much to do and see and staff is sooo nice and helpful.

Reviewed on Apr 5, 2026

Cathedral Hill Hotel

Cathedral Hill Hotel

2 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $596, price is now $398 per person
$398
per person
Jun 5 - Jun 9
found 24 hours ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
7.2/10 Good! (680 reviews)
The experience was amazing. First time in SF. The hotel overall was clean. Offcourse outside it’s out of their control but once inside it was great. Staff is amazing. Rooms are clean and comfortable. Would definitely stay there again.

Reviewed on Apr 13, 2026

The Huntington Hotel

The Huntington Hotel

5 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $1,192, price is now $799 per person
$799
per person
Jun 6 - Jun 8
found 5 hours ago
Roundtrip flight included
Carlsbad (CLD) to San Francisco (SFO)
10/10 Exceptional! (2 reviews)
After a long hiatus, the Hunington is back, and thanks to the owners and Ken Faulk, the property is as it was in 1980 but with the addition of a lobby bar and understated elegance in the all new rooms and interiors. The Big Four looks like it was never touched. I never imagined an old hotel that everyone loved could have been brought back so elegantly.

Reviewed on Mar 27, 2026

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South San Francisco Hotel Deals

Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North

2 out of 5
326 S Airport Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
The price is $72 total per night from Apr 19 to Apr 20
$72 total
per night
Apr 19 - Apr 20
6/10 (3,485 reviews)
No parking

Reviewed on Apr 17, 2026

Travelodge by Wyndham San Francisco Airport North
Best Western Plus Grosvenor Airport Hotel

Best Western Plus Grosvenor Airport Hotel

3 out of 5
380 S Airport Boulevard South San Francisco CA
Fully refundableReserve now, pay when you stay
The price is $122 total per night from Apr 18 to Apr 19
$122 total
per night
Apr 18 - Apr 19
8.4/10 Very Good! (1,762 reviews)
I come just for the Breakfast & wonderful Staff..

Reviewed on Apr 17, 2026

Best Western Plus Grosvenor Airport Hotel
DoubleTree by Hilton San Francisco South Airport Blvd

DoubleTree by Hilton San Francisco South Airport Blvd

4 out of 5
275 S Airport Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
The price is $123 total per night from Apr 25 to Apr 26
$123 total
per night
Apr 25 - Apr 26
8.4/10 Very Good! (2,233 reviews)
Room and common areas are clean. Room was updated. Sink drain seemed to have been backed up water took some time to go down and air conditioner wasn’t cooling the room but thankfully I can open the window. But being next to the airport it was loud with window open. Only stayed there for our last ...

Reviewed on Apr 17, 2026

DoubleTree by Hilton San Francisco South Airport Blvd
See all 5,070 properties in South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best South San Francisco Vacation Packages

South San Francisco Essential Information

Language
English
Currency
U.S dollars
Closest Airport
San Francisco Intl. Airport (SFO)
Population
67,300
Max Temp Winter
60ºF
Max Temp Summer
70ºF
Top Sights
Ocean Beach, California Academy of Sciences and San Francisco Zoo

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Frequently asked questions

How much does a South San Francisco vacation package cost?
You can grab a vacation package to this destination from $391 on Expedia. However, how much your vacation to South San Francisco costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to South San Francisco?
You're likely to find reduced prices and better availability in February, October and December. Check out our cheap South San Francisco vacation packages and you could land some great off-season discounts.
How many days is enough for South San Francisco?
With a well-organized itinerary, you can easily tick off the top South San Francisco attractions in a few days. But if you'd like to explore off the beaten track or go on day tours, think about booking your South San Francisco vacation for longer.
Is it worth booking a vacation package to South San Francisco?
It's no wonder a South San Francisco vacation is on the must-do list of many travelers. Well-known attractions like K1 Speed San Francisco are just the beginning of what you can explore here.
How to find the best South San Francisco package deals?
Finding a cheap South San Francisco package deal is a breeze with Expedia. Once you've entered your preferred dates and destination under our "Packages" tab, set your budget range, apply a few filters and browse what's available. You can tailor your search by "Property class," "Number of bedrooms," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most pocket-friendly South San Francisco package deals. Want a simple trick to get the biggest savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are generally lower.
Is it cheaper to book a South San Francisco vacation as a package?
You can enjoy significant savings on your next South San Francisco retreat by booking a tailored vacation package. Check the "Package" heading, then select your destination and travel dates to browse the best hotel and flight prices. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to South San Francisco?
Enjoy fantastic discounts by reserving your flights early with Expedia. If being spontaneous is more your thing, snap up one of our last-minute deals for an impromptu South San Francisco adventure.
How to plan a trip to South San Francisco?

  1. Choose your dates: What you'd like to do in South San Francisco and your favorite season can help you decide when to travel.
  2. Set a budget: Factor in expenses like flights, transportation and food when calculating how much to set aside for your trip to South San Francisco. Then, choose a hotel that fits your budget, whether that's an economical stay or a deluxe getaway.
  3. Organize your South San Francisco getaway with our trip planning tool: Look for and book stays and experiences all in one place. You can also collaborate with your group to plan an unforgettable trip to South San Francisco together.
  4. Determine how many days away: Start by compiling a list of the sights and activities you want to get to in South San Francisco. Then, estimate how long you'll need at each, including any travel time.
  5. Combine your hotel and flights: Epic destination, check. Length of stay, check. All that's left now is to pick a South San Francisco vacation package that brings all your bookings together.
  6. Book any excursions or activities: Now to the fun part — locking in everything you want to see and do. Explore some of the best things to do in South San Francisco in South San Francisco and book your tickets in advance to save time (and maybe some money too!).

Does Expedia offer Book Now, Pay Later South San Francisco vacation packages?
If you're anything like us, you love traveling but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can break down the overall cost of your South San Francisco trip across 3, 6 or 12 months. There are also no hidden or late payment fees, so you can snap up great vacation packages with payment plans as soon as you see them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.