South San Francisco Vacations from $523

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Your South San Francisco Vacation

Lock in a South San Francisco vacation package and get ready to experience the best of this lively city. Consider basing yourself in the neighborhood of Sharp Park, which is great for families, nature and golfing. Make your trip to South San Francisco even more fun by including some sightseeing. San Francisco State University, Cow Palace and Pacifica State Beach are among the major attractions worth exploring. Browse Expedia's wide range of travel options and start organizing your ideal vacation to South San Francisco now.

The Latest South San Francisco vacation packages

Price found within the past 48 hours. Click for updated prices.
Cathedral Hill Hotel

Cathedral Hill Hotel

Downtown San Francisco
Save 100% on your flight
$523
per person
Oct 22 - Oct 28
found 22 hours ago
Roundtrip flight included
Atlanta (ATL) to San Francisco (SFO)
7.2/10 Good! (737 reviews)
I only stayed for two days, but the experience was disappointing. I arrived at 2:30 PM, just 30 minutes before the 3:00 PM check-in time, and had to wait standing because the reception area had no chairs. The room was never cleaned or organized during my stay. Used towels were not exchanged, but after informing the front desk, I was simply given new towels and had to carry them myself to the third floor. The Wi‑Fi was very slow, frequently disconnected, and unreliable. Overall, I do not recommend this place.

Reviewed on Sep 11, 2026

 The Huntington Hotel

The Huntington Hotel

Downtown San Francisco
Save 100% on your flight
$1,815
per person
Oct 22 - Oct 28
found 22 hours ago
Roundtrip flight included
Atlanta (ATL) to San Francisco (SFO)
9.6/10 Exceptional! (34 reviews)
Cavallo Point

Cavallo Point

Save 100% on your flight
$812
per person
Dec 4 - Dec 7
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Francisco (SFO)
9.2/10 Wonderful! (1,002 reviews)
1 Hotel San Francisco

1 Hotel San Francisco

Downtown San Francisco
Save 100% on your flight
$2,273
per person
Oct 22 - Oct 28
found 22 hours ago
Roundtrip flight included
Atlanta (ATL) to San Francisco (SFO)
9.2/10 Wonderful! (606 reviews)
Stanford Court San Francisco

Stanford Court San Francisco

Downtown San Francisco
$632
per person
Nov 25 - Nov 29
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Francisco (SFO)
9/10 Wonderful! (1,631 reviews)
The staff were so friendly and helpful, couldn’t do enough for you. The bar area is great, the rooms are comfortable and spacious. Location is right at the top of the steep hill at California St but the cable car stop is also there. The only reason I haven’t given it a 5* is the breakfast could be improved. You have to hand in a breakfast buffet voucher (pay extra for à la carte) and you are handed a plate (v old and scratched). Options are limited and no table service. You have to make your own tea in a paper cup. That doesn’t make it a luxury hotel in my view.

Reviewed on Sep 17, 2026

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Stay near popular South San Francisco attractions

San Bruno Point Park

7.8/10 (451 reviews)
Point San Bruno Park offers panoramic views of San Francisco Bay and close-up aircraft sightings from nearby SFO. Stroll the waterfront trails and find a peaceful picnic spot away from the city's bustle.
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South San Francisco Convention Center

7.8/10 (668 reviews)
The South San Francisco Conference Center offers versatile meeting spaces with modern amenities near SFO airport. Business travelers appreciate its convenient location and comprehensive event services.
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San Francisco Baking Institute

7.6/10 (423 reviews)
Explore the campus of San Francisco Baking Institute during your visit to South San Francisco. Amble around this vibrant area's seaside and enjoy its top-notch restaurants.
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See's Candies

8.0/10 (474 reviews)
This American-made chocolate factory store welcomes visitors with the intoxicating aroma of fresh confections. Customize your own box of premium candies and savor the complimentary sample that greets every guest.
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South San Francisco Hillside Sign

You can find out about the history of South San Francisco with a stop at South San Francisco Hillside Sign.
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K1 Speed San Francisco

7.6/10 (330 reviews)
Race electric go-karts at top speeds on K1 Speed's professionally designed indoor track. For the ultimate experience, arrive on weekday afternoons when the track is less crowded.
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Sign Hill Park

Explore the great outdoors at Sign Hill Park, a lovely green space in South San Francisco. Check out the shops and top-notch restaurants in this family-friendly area.
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What to do in South San Francisco

Official Alcatraz Island Prison Tour with Free App Audio Packages

Alcatraz Inside Prison Tour with Free App Audio Packages

$86
per adult
94% of travellers recommend
Alcatraz Inside Prison Tour with Free App Audio Packages
California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

$49
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
San Francisco City Lights Cruise

California Sunset Cruise (2-hours)

$58
per adult
94% of travellers recommend
California Sunset Cruise (2-hours)
See all activities in South San Francisco

South San Francisco Hotel Deals

Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North

326 S Airport Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
$71 nightly
$85 total
Sep 27 - Sep 28
Total with taxes and fees
6/10 (4,058 reviews)
"This place is horrible and expensive. The room was dirty. The lights didn’t work. The working outlet was on the door frame!!! The only working vending machine was in the lobby. The only good thing about this place is being able to park your car and take the shuttle. Will not stay here again!"

Reviewed on Sep 17, 2026

Travelodge by Wyndham San Francisco Airport North
Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point

250 Gateway Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
$139 nightly
$163 total
Oct 16 - Oct 17
Total with taxes and fees
8.8/10 Excellent! (1,768 reviews)
"Rooms were spacious. I wish the fridges had an actual freezer. Breakfast was delicious with lots of quick options or the made to order. The lay out was really neat too."

Reviewed on Sep 17, 2026

Embassy Suites by Hilton San Francisco Airport Oyster Point
DoubleTree by Hilton San Francisco South Airport Blvd

DoubleTree by Hilton San Francisco South Airport Blvd

275 S Airport Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
$122 nightly
$144 total
Oct 17 - Oct 18
Total with taxes and fees
DoubleTree by Hilton San Francisco South Airport Blvd
See all 4,549 properties in South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best South San Francisco Vacation Packages

South San Francisco Essential Information

Language
English
Currency
U.S dollars
Closest Airport
San Francisco Intl. Airport (SFO)
Population
67,300
Max Temp Winter
60ºF
Max Temp Summer
70ºF
Top Sights
Ocean Beach, California Academy of Sciences and San Francisco Zoo

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Frequently asked questions

How much does a South San Francisco vacation package cost?
You can grab a vacation package to this destination from $523 on Expedia. However, how much your vacation to South San Francisco costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to South San Francisco?
You're likely to find reduced prices and better availability in February, October and December. Check out our cheap South San Francisco vacation packages and you could land some great off-season discounts.
How many days is enough for South San Francisco?
With a well-organized itinerary, you can easily tick off the top South San Francisco attractions in a few days. But if you'd like to explore off the beaten track or go on day tours, think about booking your South San Francisco vacation for longer.
Is it worth booking a vacation package to South San Francisco?
It's no wonder a South San Francisco vacation is on the must-do list of many travelers. Well-known attractions like K1 Speed San Francisco are just the beginning of what you can explore here.
How to find the best South San Francisco package deals?
Finding a cheap South San Francisco package deal is a breeze with Expedia. Once you've entered your preferred dates and destination under our "Packages" tab, set your budget range, apply a few filters and browse what's available. You can tailor your search by "Property class," "Number of bedrooms," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most pocket-friendly South San Francisco package deals. Want a simple trick to get the biggest savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are generally lower.
Is it cheaper to book a South San Francisco vacation as a package?
You can enjoy significant savings on your next South San Francisco retreat by booking a tailored vacation package. Check the "Package" heading, then select your destination and travel dates to browse the best hotel and flight prices. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to South San Francisco?
Enjoy fantastic discounts by reserving your flights early with Expedia. If being spontaneous is more your thing, snap up one of our last-minute deals for an impromptu South San Francisco adventure.
How to plan a trip to South San Francisco?
  1. Choose your dates: What you'd like to do in South San Francisco and your favorite season can help you decide when to travel.
  2. Set a budget: Factor in expenses like flights, transportation and food when calculating how much to set aside for your trip to South San Francisco. Then, choose a hotel that fits your budget, whether that's an economical stay or a deluxe getaway.
  3. Organize your South San Francisco getaway with our trip planning tool: Look for and book stays and experiences all in one place. You can also collaborate with your group to plan an unforgettable trip to South San Francisco together.
  4. Determine how many days away: Start by compiling a list of the sights and activities you want to get to in South San Francisco. Then, estimate how long you'll need at each, including any travel time.
  5. Combine your hotel and flights: Epic destination, check. Length of stay, check. All that's left now is to pick a South San Francisco vacation package that brings all your bookings together.
  6. Book any excursions or activities: Now to the fun part — locking in everything you want to see and do. Explore some of the best things to do in South San Francisco in South San Francisco and book your tickets in advance to save time (and maybe some money too!).
Does Expedia offer Book Now, Pay Later South San Francisco vacation packages?
If you're anything like us, you love traveling but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can break down the overall cost of your South San Francisco trip across 3, 6 or 12 months. There are also no hidden or late payment fees, so you can snap up great vacation packages with payment plans as soon as you see them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.