Find all hotels by Best Western in Spartanburg, SC from $72

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Compare rooms and suites by Best Western in Spartanburg with rates, reviews, and availability. Most hotels are fully refundable.

"Great place to spend night when flying out of GSP. Shuttle service convenient and free hot breakfast!!"

$79 total

includes taxes & fees

May 22 - May 23

"The young lady that did my check in was incredibly friendly and customer service oriented. Very impressive!"

$86 total

includes taxes & fees

May 28 - May 29

Best Western Spartanburg Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Best Western hotels in Spartanburg, South Carolina. Known for well-appointed rooms and friendly, personalized service, each of the top Best Western Spartanburg hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Spartanburg Best Western locations may even offer extra little benefits and discounts for frequent travelers.