
West Seneca Vacations from $405
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Find the right fit
Rest easy
Your West Seneca Vacation
When a city getaway is calling, answer it with a West Seneca vacation package. The neighborhood of Downtown Buffalo, which is great for nightlife, shopping and bars and pubs, makes a fantastic base for your adventures. A trip to West Seneca is a great opportunity to see the sights. Be sure to look around well-known attractions like Highmark Stadium, Buffalo and Erie County Botanical Gardens and Walden Galleria Mall. Expedia has what you need to escape your routine. Tailor your vacation to West Seneca to suit your travel style, whatever that may be.
The Latest West Seneca vacation packages

Holiday Inn Express Grand Island - Niagara Falls by IHG
Reviewed on Jul 15, 2025

Travelodge by Wyndham Niagara Falls
Reviewed on Jul 14, 2025


THE 1023 With Private Yard & Parking, Near Falls & Casino by Niagara Hospitality
Reviewed on Jun 20, 2025

Discover the most popular places to visit in West Seneca

University At Buffalo - North Campus
Explore the campus of University At Buffalo - North Campus, a top college in Amherst. Experience the area's acclaimed theater scene and entertainment choices.

Highmark Stadium
Catch an event at Highmark Stadium during your trip to Orchard Park. Experience the area's entertainment choices and great live music.

Buffalo Zoo
See more than 1,200 animals at this small zoo in Buffalo’s Delaware Park. Explore the rainforest building or see the big cats of the African plains.
What to do in West Seneca

Theodore Roosevelt Inaugural National Historic Site Admission and Guided Tour

Niagara Falls Self-Guided Driving Audio Tour from Toronto
West Seneca Hotel Deals

Country Inn & Suites by Radisson, Buffalo South I-90, NY
Reviewed on Jul 13, 2025

Buffalo Airport Hotel
Reviewed on Jul 13, 2025

M Hotel Buffalo
Reviewed on Jul 12, 2025
Find the Best West Seneca Vacation Packages
West Seneca Essential Information
Language | English |
---|---|
Currency | U.S dollars |
Closest Airport | Buffalo Niagara Intl. Airport (BUF) |
Population | 44,700 |
Max Temp Winter | 30ºF |
Max Temp Summer | 75ºF |
Top Sights | Buffalo Zoo, Buffalo Museum of Science and Albright - Knox Art Gallery |
More vacations you might like
Frequently asked questions
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Hotels near Southgate Plaza
- Hotels near Charles E. Burchfield Nature and Art Center
- Buffalo Hotels
- Hotels near East Seneca
- Hotels near Cazenovia Golf Course
- Hotels near Cazenovia Park
- Hotels near Trocaire College
- Hotels near Highmark Stadium
- Hotels near The Botanical Gardens
- Hotels near Our Lady of Victory Basilica
- Hotels near Buffalo and Erie County Botanical Gardens
- Hotels near Harvest Hill Golf Course
- Hotels near South Park Golf Course
- Lackawanna Hotels
- Hotels near Stiglmeier Park
- Motels in Lackawanna
- B&B in Lackawanna
- Cheap Hotels in Lackawanna
- Apartments in Lackawanna
- Hotels with a Pool in Lackawanna
- Hotels with Hot Tubs in Lackawanna
- Casino Hotels in Lackawanna
- Hotels on the Lake in Lackawanna
- Quiet Resorts & in Lackawanna
- Beach Hotels in Lackawanna
- 5 Star Hotels in Lackawanna
- Family Hotels in Lackawanna
- Hotels near Reinstein Woods Nature Preserve and Environmental Education Center
- Hotels near Buffalo Fire Historical Society
- Hotels near Orchard Acres Park
- Cheektowaga Hotels
- Hotels near McKinley Mall
- Cheap Hotels in Cheektowaga
- Motels in Cheektowaga
- Hotels with an Indoor Pool in Cheektowaga
- Hotels with Restaurants in Cheektowaga
- Iron Island Hotels
- Marriott Hotels & Resorts in Cheektowaga
- Pet-friendly Hotels in Cheektowaga
- Red Roof Inn Hotels in Cheektowaga
- B&B in Cheektowaga
- Extended Stay Hotels in Cheektowaga
- Luxury Hotels in Cheektowaga
- Hotel Wedding Venues Hotels in Cheektowaga
- Hotels with Kitchenettes in Cheektowaga
- Casino Hotels in Cheektowaga
- 4 Star Hotels in Cheektowaga
- Hotels with Hot Tubs in Cheektowaga
- Hotels with Connecting Rooms in Cheektowaga
- Historic Hotels in Cheektowaga
- Romantic Hotels in Cheektowaga
- Cabin Rentals in Cheektowaga
- La Quinta Inn & Suites Hotels in Cheektowaga
- Hotels with Free Breakfast in Cheektowaga
- Hotels with an Outdoor Pool in Cheektowaga
- Best Western Hotels in Cheektowaga
- Motel 6 Hotels in Cheektowaga
- Hotels with Bars in Cheektowaga
- Southgate Plaza
- Charles E. Burchfield Nature and Art Center
- Enjoy The Journey Art Gallery
- Cazenovia Golf Course
- Harvest Hill Golf Course
- Our Lady of Victory Basilica
- The Botanical Gardens
- South Park Golf Course
- Stiglmeier Park
- Lackawanna Vacations
- Reinstein Woods Nature Preserve and Environmental Education Center
- Visit Lackawanna
- Orchard Acres Park
- Highmark Stadium
- McKinley Mall
- Hennepin Park
- Cheektowaga Vacations
- Holiday Twin Rinks
- Iron Island Museum
- Blasdell Vacations
- Visit Iron Island
- Visit Cheektowaga
- Car rentals near East Seneca
- Car rentals near Blossom
- Car rentals near Lackawanna
- Car rentals near Buffalo
- Car rentals near Bellevue
- Car rentals near Cheektowaga
- Enterprise Rental Cars in Cheektowaga
- Hertz Rental Cars in Cheektowaga
- Budget Rental Cars in Cheektowaga
- Advantage Rent-A-Car Rental Cars in Cheektowaga