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Your West Seneca Vacation
When a city getaway is calling, answer it with a West Seneca vacation package. The neighborhood of Downtown Buffalo, which is great for nightlife, shopping and bars and pubs, makes a fantastic base for your adventures. A trip to West Seneca is a great opportunity to see the sights. Be sure to look around well-known attractions like Highmark Stadium, Buffalo and Erie County Botanical Gardens and Walden Galleria Mall. Expedia has what you need to escape your routine. Tailor your vacation to West Seneca to suit your travel style, whatever that may be.
The Latest West Seneca vacation packages

M Hotel Buffalo
Reviewed on Nov 27, 2025

Buffalo Marriott Niagara
Reviewed on Nov 13, 2025

The Richardson Hotel
Reviewed on Nov 27, 2025


Buffalo Airport Hotel
Reviewed on Nov 28, 2025
Discover the most popular places to visit in West Seneca

Highmark Stadium
Catch an event at Highmark Stadium during your trip to Orchard Park. Experience the area's entertainment choices and great live music.

University At Buffalo - North Campus
Enjoy the collegiate vibe when you visit University At Buffalo - North Campus, during your trip to Amherst. Experience the area's great live music and entertainment choices.

Buffalo Zoo
See more than 1,200 animals at this small zoo in Buffalo’s Delaware Park. Explore the rainforest building or see the big cats of the African plains.
What to do in West Seneca

Theodore Roosevelt Inaugural National Historic Site Admission and Guided Tour

Buffalo Sabres Ice Hockey Game at Keybank Center

Niagara Falls USA: Maid of the Mist & Cave Adventure
West Seneca Hotel Deals

Staybridge Suites West Seneca by IHG
It was a great setup for our family of 5 to travel. Lots of space, clean, and good location.
Reviewed on Nov 15, 2025

Country Inn & Suites by Radisson, Buffalo South I-90, NY
Nice place
Reviewed on Nov 23, 2025

Hampton Inn Buffalo South/I-90
Left early; did not have breakfast, just coffee
Reviewed on Nov 15, 2025
Find the Best West Seneca Vacation Packages
West Seneca Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Buffalo Niagara Intl. Airport (BUF) |
Population | 44,700 |
Max Temp Winter | 30ºF |
Max Temp Summer | 75ºF |
Top Sights | Buffalo Zoo, Buffalo Museum of Science and Albright - Knox Art Gallery |
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- Southgate Plaza
- Charles E. Burchfield Nature and Art Center
- Enjoy The Journey Art Gallery
- Cazenovia Golf Course
- Harvest Hill Golf Course
- Our Lady of Victory Basilica
- The Botanical Gardens
- South Park Golf Course
- Stiglmeier Park
- Lackawanna Vacations
- Reinstein Woods Nature Preserve and Environmental Education Center
- Visit Lackawanna
- Orchard Acres Park
- Highmark Stadium
- McKinley Mall
- Hennepin Park
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- Holiday Twin Rinks
- Iron Island Museum
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