Find 5 Star Hotels in Santa Cruz from $64
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Marriott Santa Cruz de la Sierra Hotel

Novotel Santa Cruz De La Sierra

Radisson Hotel Santa Cruz
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Camino Real Hotel
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Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

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Marriott Santa Cruz de la Sierra Hotel

Novotel Santa Cruz De La Sierra
Find out more about Santa Cruz
Why not ask for the best of accommodations on your excursion to Santa Cruz? After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Santa Cruz so popular in the last year. There's no reason to delay a getaway to Santa Cruz any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Reserve one of our 5-star hotels in Santa Cruz and indulge in the finer things in life for a while. What are you waiting for?
Get a Great Deal on 5-Star Hotels in Santa Cruz
You'll have a fantastic time at one of these 5-star hotels. Michelin-starred restaurants, exceptional customer care, and rejuvenating spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. What creature comforts do you want in your lodging? 24-hour room service, so you can order that chocolate soufflé© in the wee hours of the morning? A mud wrap treatment that will leave you feeling great? Butler services? Whatever it is your heart desires, you're bound to find it here.
Ready for experiences outside your hotel room? Don't worry. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Santa Cruz are the perfect place to rest up after a busy day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.
Make Your Escape
The results are in, and Santa Cruz 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. It's time to plan your next great escape -- Expedia can help you land a great deal on accommodation. Choose one of the 5-star hotels in Santa Cruz today and soothe yourself in luxe surroundings tomorrow.
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