Vacation Rentals in Santa Cruz

Top Cities in Santa Cruz

Our top choices for Santa Cruz vacation rentals

3.5 star property
9.0 out of 10, Wonderful, (87 reviews)
"Good price, great hotel!"
United States
James
$36 nightly
The price is $36
Apr 21 - Apr 22
Premium Suites Deluxe Aparthotel Equipetrol

Aparthotel in Santa Cruz

Terranova Suites
3.5 star property
8.0 out of 10, Very Good, (90 reviews)
"Easy to access"
United States
Dorothy
$52 nightly
The price is $52
Mar 23 - Mar 24
Terranova Suites

Aparthotel in Santa Cruz

Equipetrol Suites Apart Hotel
2.5 star property
8.8 out of 10, Excellent, (13 reviews)
"Perfect hotel"
Turkey
Yener
$48 nightly
The price is $48
Mar 22 - Mar 23
Equipetrol Suites Apart Hotel

Aparthotel in Santa Cruz

Apart Hotel Toborochi
3.0 star property
8.8 out of 10, Excellent, (60 reviews)
"Very comfortable and quiet place and very good location. "
United States
Luis
Apart Hotel Toborochi

Apartment in Santa Cruz

AMERICA APARTMENTS
3.0 star property
10.0 out of 10, Exceptional, (1 review)
"Clean room, great staff "
Canada
Peter
$55 nightly
The price is $55
Mar 22 - Mar 23
AMERICA APARTMENTS
3.5 star property
8.6 out of 10, Excellent, (100 reviews)
"Place is clean , safe area , walking distance to shops "
United States
Nataly
Apart Hotel Premium Suites Santa Cruz

Apartment in Santa Cruz de la Sierra

Traveler's Hideout
10.0 out of 10, Exceptional, (1 review)
"The place was cozy, neat, and th host was very attentive and supportive. I recomend this place"
United States
Mauricio O.
$76 nightly
The price is $76
Mar 22 - Mar 23
Traveler's Hideout

Apartment in Santa Cruz de la Sierra

Apartment in Patio Design with private garage
$58 nightly
The price is $58
Mar 23 - Mar 24
Apartment in Patio Design with private garage

Apartment in Santa Cruz de la Sierra

Dpt TV 58" / Swimming pool / Cowork / Gym / Queen Bed
10.0 out of 10, Exceptional, (1 review)
$51 nightly
The price is $51
Mar 23 - Mar 24
Dpt TV 58" / Swimming pool / Cowork / Gym / Queen Bed

Apartment in Santa Cruz de la Sierra

Casa de 2 Habitaciones en zona norte
8.0 out of 10, Very Good, (1 review)
"Muy buen departamento, bien ubicado"
United States
Elva
$59 nightly
The price is $59
Mar 22 - Mar 23
Casa de 2 Habitaciones en zona norte
10.0 out of 10, Exceptional, (2 reviews)
"Zona tranquila y todo cerca supermercados tiendas etc"
Mexico
Fabricio O.
$60 nightly
The price is $60
Mar 22 - Mar 23
Tranquil apartment with WiFi in Santa Cruz de la Sierra

Apartment in Santa Cruz de la Sierra

Apartamento confortable para 2 personas
$42 nightly
The price is $42
Mar 26 - Mar 27
Apartamento confortable para 2 personas

Apartment in Santa Cruz de la Sierra

A must-see studio apartment in Sirari-Equipetrol
$58 nightly
The price is $58
Mar 27 - Mar 28
A must-see studio apartment in Sirari-Equipetrol
$48 nightly
The price is $48
Mar 23 - Mar 24
Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC
$35 nightly
The price is $35
Mar 22 - Mar 23
Chalet indept, amplio, acogedor, hermoso jardin Aire C wifi, espa.xcocinar.

Apartment in Santa Cruz de la Sierra

Luxury apartment
$45 nightly
The price is $45
Mar 23 - Mar 24
Luxury apartment

Apartment in Santa Cruz de la Sierra

de 6 a 8 Personas Cómodamente Alojadas
10.0 out of 10, Exceptional, (1 review)
"We enjoyed this apartment. The 4 bedroom and private bathrooms of this unit, work out really well for us. The building has a great security .We were also in a good location. Grocery store was in a walking distance. Junior and Moises were so helpful."
Canada
Lucy N.
$100 nightly
The price is $100
Mar 22 - Mar 23
de 6 a 8 Personas Cómodamente Alojadas

Cabin in Samaipata

Samaipata Glamping
3.5 star property
$174 nightly
The price is $174
Mar 29 - Mar 30
Samaipata Glamping
$50 nightly
The price is $50
Mar 27 - Mar 28
Cozy 2-bedroom apartment with AC, WiFi in enjoyable Santa Cruz
$60 nightly
The price is $60
Mar 22 - Mar 23
Beautiful Loft in a brand new Condo, 10 minutes from business center.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

Discover your perfect Santa Cruz vacation rental with Expedia

How many vacation rentals are available in Santa Cruz?


Expedia has plenty of vacation rentals to choose from in and around  Santa Cruz, so you’re guaranteed to find the right one for you. 


How much is a vacation rental in Santa Cruz?


The selection of Santa Cruz vacation rentals we have selected for you start as low as $35 per night. Entering your travel dates in the search wizard you might find even better deals!


What type of vacation rental can I get in Santa Cruz?


Vacation rentals in Santa Cruz come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of Santa Cruz vacation rentals to suit everyone. 


Why should I choose a vacation rental in Santa Cruz?


Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A Santa Cruz vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. 


How do I find the best deal on a vacation rental in Santa Cruz?


Find vacation rentals in Santa Cruz by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in Santa Cruz.  


What amenities are available in a vacation rental in Santa Cruz?


The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in Santa Cruz vacation rentals designed to suit every budget and trip type.


When is the best time to stay in a vacation rental in Santa Cruz?   


Everytime is a great time to head to Santa Cruz! Staying in a Santa Cruz vacation rentals you will always find lots going on to keep you entertained. 


Why book a vacation rental with Expedia?


Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in Santa Cruz. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect Santa Cruz vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in Santa Cruz, you can save even more.


Can I cancel my vacation rental through Expedia?  


Yes, you can cancel or change your Santa Cruz vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.