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Vacation Rentals in Santa Cruz

Top Cities in Santa Cruz

Our top choices for Santa Cruz vacation rentals

1. Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
8.8 out of 10, Excellent, (121 reviews)
"great place to stay!"
United States
Luisa
$41 nightly
The price is $41
Oct 25 - Oct 26
Premium Suites Deluxe Aparthotel Equipetrol

2. Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (107 reviews)
"Great location."
United States
Ruben
$23 nightly
The price is $23
Oct 24 - Oct 25
Apart Hotel Premium Suites Santa Cruz

3. Terranova Suites

Terranova Suites
3.5 star property
Santa Cruz
8.0 out of 10, Very good, (91 reviews)
"Easy to access"
United States
Dorothy
$52 nightly
The price is $52
Oct 25 - Oct 26
Terranova Suites

4. 58" TV / Swimming Pool / Coworking Space / Fitness Center / Queen-Size Bed

58" TV / Swimming Pool / Coworking Space / Fitness Center / Queen-Size Bed
Equipetrol
8.0 out of 10, Very good, (2 reviews)
$54 nightly
The price is $54
Oct 26 - Oct 27
58" TV / Swimming Pool / Coworking Space / Fitness Center / Queen-Size Bed

5. Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.8 out of 10, Excellent, (13 reviews)
"Perfect hotel"
Turkey
Yener
$51 nightly
The price is $51
Oct 24 - Oct 25
Equipetrol Suites Apart Hotel

6. AMERICA APARTMENTS

AMERICA APARTMENTS
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (3 reviews)
"Clean room, great staff "
Canada
Peter
$39 nightly
The price is $39
Oct 24 - Oct 25
AMERICA APARTMENTS

7. POX: 24th Floor, Green Tower | Luxury and Panoramic Views

POX: 24th Floor, Green Tower | Luxury and Panoramic Views
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
"Very comfortable and nice view and the super clean"
United States
Carlos
$105 nightly
The price is $105
Oct 24 - Oct 25
POX: 24th Floor, Green Tower | Luxury and Panoramic Views

8. Menacho Apartment - Mangales Blue - Norte

Menacho Apartment - Mangales Blue - Norte
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
"We arrived at 12:30 am due to our flight and I let the host know of our late arrival time. He had no problem. When checking in I made an error and I couldn’t figure out how to get there. I called the host as late as it was, he answered no problem and was super nice and helpful. He was very communicative although out our stay. Room was fully functional. Had a kitchen with all the necessary utensils, living room area with a tv and a couch that became a bed for our kids. Private master bedroom...
Canada
Evelyn
$33 nightly
The price is $33
Nov 1 - Nov 2
Menacho Apartment - Mangales Blue - Norte

9. Samaipata Glamping

Samaipata Glamping
3.0 star property
Samaipata
$44 nightly
The price is $44
Nov 2 - Nov 3
Samaipata Glamping

10. Aqua: Loft Artistico Urbano

Aqua: Loft Artistico Urbano
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
"Excellent atencion todo muy comodo bonito limpio gracias"
United States
Nestor C.
Aqua: Loft Artistico Urbano

11. Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC

Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC
Equipetrol
$48 nightly
The price is $48
Oct 27 - Oct 28
Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC

12. Apartment with a balcony, pool, fitness center, and coworking space at Equipe

Apartment with a balcony, pool, fitness center, and coworking space at Equipe
Equipetrol
$55 nightly
The price is $55
Nov 2 - Nov 3
Apartment with a balcony, pool, fitness center, and coworking space at Equipe

13. Apart Hotel Toborochi

Apart Hotel Toborochi
3.0 star property
Equipetrol
8.8 out of 10, Excellent, (61 reviews)
"Very comfortable and quiet place and very good location. "
United States
Luis
$73 nightly
The price is $73
Nov 1 - Nov 2
Apart Hotel Toborochi

14. Hermoso apartamento con dos habitaciones en la zona más segura de Santa Cruz.

Hermoso apartamento con dos habitaciones en la zona más segura de Santa Cruz.
Santa Cruz de la Sierra
$46 nightly
The price is $46
Oct 27 - Oct 28
Hermoso apartamento con dos habitaciones en la zona más segura de Santa Cruz.

15. Patio-style apartment with a private garage

Patio-style apartment with a private garage
Santa Cruz de la Sierra
$58 nightly
The price is $58
Oct 26 - Oct 27
Patio-style apartment with a private garage

16. Apartment with a workspace / pool / gym / sleeper sofa

Apartment with a workspace / pool / gym / sleeper sofa
Equipetrol
$57 nightly
The price is $57
Oct 29 - Oct 30
Apartment with a workspace / pool / gym / sleeper sofa

17. Enchanting studio with AC in Santa Cruz de la Sierra

Enchanting studio with AC in Santa Cruz de la Sierra
Equipetrol
$47 nightly
The price is $47
Oct 24 - Oct 25
Enchanting studio with AC in Santa Cruz de la Sierra

18. Beautiful Loft in a brand new Condo, 10 minutes from business center.

Beautiful Loft in a brand new Condo, 10 minutes from business center.
Santa Cruz de la Sierra
2.0 out of 10, (1 review)
$57 nightly
The price is $57
Oct 24 - Oct 25
Beautiful Loft in a brand new Condo, 10 minutes from business center.

19. Comfort in the best area of Santa Cruz—perfect for business travelers and tourists!!

Comfort in the best area of Santa Cruz—perfect for business travelers and tourists!!
Santa Cruz de la Sierra
$57 nightly
The price is $57
Oct 30 - Oct 31
Comfort in the best area of Santa Cruz—perfect for business travelers and tourists!!

20. Inspiring Views • Enveloping Comfort

Inspiring Views • Enveloping Comfort
Equipetrol
$55 nightly
The price is $55
Oct 29 - Oct 30
Inspiring Views • Enveloping Comfort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

Discover your perfect Santa Cruz vacation rental with Expedia

How many vacation rentals are available in Santa Cruz?


Expedia has plenty of vacation rentals to choose from in and around  Santa Cruz, so you’re guaranteed to find the right one for you. 


How much is a vacation rental in Santa Cruz?


The selection of Santa Cruz vacation rentals we have selected for you start as low as $23 per night. Entering your travel dates in the search wizard you might find even better deals!


What type of vacation rental can I get in Santa Cruz?


Vacation rentals in Santa Cruz come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of Santa Cruz vacation rentals to suit everyone. 


Why should I choose a vacation rental in Santa Cruz?


Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A Santa Cruz vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. 


How do I find the best deal on a vacation rental in Santa Cruz?


Find vacation rentals in Santa Cruz by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in Santa Cruz.  


What amenities are available in a vacation rental in Santa Cruz?


The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in Santa Cruz vacation rentals designed to suit every budget and trip type.


When is the best time to stay in a vacation rental in Santa Cruz?   


Everytime is a great time to head to Santa Cruz! Staying in a Santa Cruz vacation rentals you will always find lots going on to keep you entertained. 


Why book a vacation rental with Expedia?


Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in Santa Cruz. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect Santa Cruz vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in Santa Cruz, you can save even more.


Can I cancel my vacation rental through Expedia?  


Yes, you can cancel or change your Santa Cruz vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.  


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