Vacation Rentals in Santa Cruz

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Top Cities in Santa Cruz

Our top choices for Santa Cruz vacation rentals

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (101 reviews)
"Great Location"
United States
Blanca
$42 nightly
The price is $42
Jun 14 - Jun 15
Premium Suites Deluxe Aparthotel Equipetrol

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.8 out of 10, Excellent, (13 reviews)
"Perfect hotel"
Turkey
Yener
$46 nightly
The price is $46
Jun 6 - Jun 7
Equipetrol Suites Apart Hotel

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (102 reviews)
"Great location."
United States
Ruben
$27 nightly
The price is $27
Jun 6 - Jun 7
Apart Hotel Premium Suites Santa Cruz

Terranova Suites

Terranova Suites
3.5 star property
Santa Cruz
8.0 out of 10, Very Good, (90 reviews)
"Easy to access"
United States
Dorothy
$52 nightly
The price is $52
Jun 7 - Jun 8
Terranova Suites

Samaipata Glamping

Samaipata Glamping
3.5 star property
Samaipata
$178 nightly
The price is $178
Jun 7 - Jun 8
Samaipata Glamping

AMERICA APARTMENTS

AMERICA APARTMENTS
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1 review)
"Clean room, great staff "
Canada
Peter
$50 nightly
The price is $50
Jun 6 - Jun 7
AMERICA APARTMENTS

Casa Vida

Casa Vida
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (2 reviews)
"buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa"
Chile
FERNANDO
$92 nightly
The price is $92
Jun 6 - Jun 7
Casa Vida

Apart Hotel Toborochi

Apart Hotel Toborochi
3.0 star property
Santa Cruz
8.8 out of 10, Excellent, (60 reviews)
"Very comfortable and quiet place and very good location. "
United States
Luis
$77 nightly
The price is $77
Jul 1 - Jul 2
Apart Hotel Toborochi

POX: 24th Floor Green Tower | Luxury and Panoramic View

POX: 24th Floor Green Tower | Luxury and Panoramic View
Santa Cruz de la Sierra
$105 nightly
The price is $105
Jun 10 - Jun 11
POX: 24th Floor Green Tower | Luxury and Panoramic View

Tranquil apartment with WiFi in Santa Cruz de la Sierra

Tranquil apartment with WiFi in Santa Cruz de la Sierra
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (2 reviews)
"Zona tranquila y todo cerca supermercados tiendas etc"
Mexico
Fabricio O.
$60 nightly
The price is $60
Jun 6 - Jun 7
Tranquil apartment with WiFi in Santa Cruz de la Sierra

Santos Apartamentos

Santos Apartamentos
3.5 star property
Santa Cruz
$135 nightly
The price is $135
Jun 12 - Jun 13
Santos Apartamentos

Casa de 2 Habitaciones en zona norte

Casa de 2 Habitaciones en zona norte
Santa Cruz de la Sierra
8.0 out of 10, Very Good, (1 review)
"Muy buen departamento, bien ubicado"
United States
Elva
$59 nightly
The price is $59
Jun 6 - Jun 7
Casa de 2 Habitaciones en zona norte

Dpt TV 58" / Swimming pool / Cowork / Gym / Queen Bed

Dpt TV 58" / Swimming pool / Cowork / Gym / Queen Bed
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
$54 nightly
The price is $54
Jun 15 - Jun 16
Dpt TV 58" / Swimming pool / Cowork / Gym / Queen Bed

Menacho Apartment - Mangales Blue - Norte

Menacho Apartment - Mangales Blue - Norte
Santa Cruz de la Sierra
$33 nightly
The price is $33
Jun 9 - Jun 10
Menacho Apartment - Mangales Blue - Norte

VERONA Cabañas - Apartamento de 3 dormitorios 6

VERONA Cabañas - Apartamento de 3 dormitorios 6
Santa Cruz de la Sierra
$199 nightly
The price is $199
Jun 6 - Jun 7
VERONA Cabañas - Apartamento de 3 dormitorios 6

BEACH HOUSE 2-bedroom condo with AC, WiFi in fabulous Santa Cruz

BEACH HOUSE 2-bedroom condo with AC, WiFi in fabulous Santa Cruz
Santa Cruz de la Sierra
$130 nightly
The price is $130
Jun 7 - Jun 8
BEACH HOUSE 2-bedroom condo with AC, WiFi in fabulous Santa Cruz

Cabaña Renacer (cozy place, garden, nature, rustic, handmade, vintage)

Cabaña Renacer (cozy place, garden, nature, rustic, handmade, vintage)
Santa Cruz de la Sierra
$165 nightly
The price is $165
Jun 8 - Jun 9
Cabaña Renacer (cozy place, garden, nature, rustic, handmade, vintage)

Experience comfort, luxury and tranquility

Experience comfort, luxury and tranquility
Santa Cruz
$95 nightly
The price is $95
Jun 7 - Jun 8
Experience comfort, luxury and tranquility

Exclusive Condominium Home - Resort Style Living with Pool and Parks 🌴🏊‍♂️

Exclusive Condominium Home - Resort Style Living with Pool and Parks 🌴🏊‍♂️
Santa Cruz de la Sierra
$93 nightly
The price is $103
Jun 6 - Jun 7
Exclusive Condominium Home - Resort Style Living with Pool and Parks 🌴🏊‍♂️

Hermoso Departamento 4 Habitaciones con Baño a 10 min del Aeropuerto

Hermoso Departamento 4 Habitaciones con Baño a 10 min del Aeropuerto
Santa Cruz de la Sierra
$87 nightly
The price is $87
Jun 6 - Jun 7
Hermoso Departamento 4 Habitaciones con Baño a 10 min del Aeropuerto
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Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

Discover your perfect Santa Cruz vacation rental with Expedia

How many vacation rentals are available in Santa Cruz?


Expedia has plenty of vacation rentals to choose from in and around  Santa Cruz, so you’re guaranteed to find the right one for you. 


How much is a vacation rental in Santa Cruz?


The selection of Santa Cruz vacation rentals we have selected for you start as low as $27 per night. Entering your travel dates in the search wizard you might find even better deals!


What type of vacation rental can I get in Santa Cruz?


Vacation rentals in Santa Cruz come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of Santa Cruz vacation rentals to suit everyone. 


Why should I choose a vacation rental in Santa Cruz?


Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A Santa Cruz vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. 


How do I find the best deal on a vacation rental in Santa Cruz?


Find vacation rentals in Santa Cruz by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in Santa Cruz.  


What amenities are available in a vacation rental in Santa Cruz?


The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in Santa Cruz vacation rentals designed to suit every budget and trip type.


When is the best time to stay in a vacation rental in Santa Cruz?   


Everytime is a great time to head to Santa Cruz! Staying in a Santa Cruz vacation rentals you will always find lots going on to keep you entertained. 


Why book a vacation rental with Expedia?


Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in Santa Cruz. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect Santa Cruz vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in Santa Cruz, you can save even more.


Can I cancel my vacation rental through Expedia?  


Yes, you can cancel or change your Santa Cruz vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.