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Vacation Rentals in Santa Cruz

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Top Cities in Santa Cruz

Our top choices for Santa Cruz vacation rentals

1. Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (114 reviews)
"great place to stay!"
United States
Luisa
$34 nightly
The price is $38
Aug 27 - Aug 28
Premium Suites Deluxe Aparthotel Equipetrol

2. Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (104 reviews)
"Great location."
United States
Ruben
$27 nightly
The price is $27
Aug 15 - Aug 16
Apart Hotel Premium Suites Santa Cruz

3. Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.8 out of 10, Excellent, (13 reviews)
"Perfect hotel"
Turkey
Yener
$42 nightly
The price is $42
Aug 16 - Aug 17
Equipetrol Suites Apart Hotel

4. Terranova Suites

Terranova Suites
3.5 star property
Santa Cruz
8.0 out of 10, Very Good, (91 reviews)
"Easy to access"
United States
Dorothy
$52 nightly
The price is $52
Aug 16 - Aug 17
Terranova Suites

5. AMERICA APARTMENTS

AMERICA APARTMENTS
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (2 reviews)
"Clean room, great staff "
Canada
Peter
$34 nightly
The price is $34
Aug 17 - Aug 18
AMERICA APARTMENTS

6. Apart Hotel Toborochi

Apart Hotel Toborochi
3.0 star property
Santa Cruz
8.8 out of 10, Excellent, (60 reviews)
"Very comfortable and quiet place and very good location. "
United States
Luis
$77 nightly
The price is $77
Aug 15 - Aug 16
Apart Hotel Toborochi

7. POX: 24th Floor Green Tower | Luxury and Panoramic View

POX: 24th Floor Green Tower | Luxury and Panoramic View
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
"Very comfortable and nice view and the super clean"
United States
Carlos
$105 nightly
The price is $105
Aug 15 - Aug 16
POX: 24th Floor Green Tower | Luxury and Panoramic View

8. Casa Vida

Casa Vida
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (2 reviews)
"buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa"
Chile
FERNANDO
$75 nightly
The price is $75
Aug 16 - Aug 17
Casa Vida

9. Dpt TV 58" / Swimming pool / Cowork / Gym / Queen Bed

Dpt TV 58" / Swimming pool / Cowork / Gym / Queen Bed
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
$54 nightly
The price is $54
Aug 18 - Aug 19
Dpt TV 58" / Swimming pool / Cowork / Gym / Queen Bed

10. Aqua: Loft Artistico Urbano

Aqua: Loft Artistico Urbano
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
"Excellent atencion todo muy comodo bonito limpio gracias"
United States
Nestor C.
$68 nightly
The price is $68
Aug 15 - Aug 16
Aqua: Loft Artistico Urbano

11. POX: Green Tower 16th floor : Luxury and elegance - 2H

POX: Green Tower 16th floor : Luxury and elegance - 2H
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
"Beautiful place, excellent location."
United States
Ruben
$110 nightly
The price is $110
Aug 15 - Aug 16
POX: Green Tower 16th floor : Luxury and elegance - 2H

12. Tranquil apartment with WiFi in Santa Cruz de la Sierra

Tranquil apartment with WiFi in Santa Cruz de la Sierra
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (2 reviews)
"Zona tranquila y todo cerca supermercados tiendas etc"
Mexico
Fabricio O.
$60 nightly
The price is $60
Aug 15 - Aug 16
Tranquil apartment with WiFi in Santa Cruz de la Sierra

13. Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC

Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC
Santa Cruz de la Sierra
$50 nightly
The price is $50
Sep 5 - Sep 6
Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC

14. Casa de 2 Habitaciones en zona norte

Casa de 2 Habitaciones en zona norte
Santa Cruz de la Sierra
8.0 out of 10, Very Good, (1 review)
"Muy buen departamento, bien ubicado"
United States
Elva
$59 nightly
The price is $59
Aug 15 - Aug 16
Casa de 2 Habitaciones en zona norte

15. Samaipata Glamping

Samaipata Glamping
3.5 star property
Samaipata
$152 nightly
The price is $152
Aug 16 - Aug 17
Samaipata Glamping

16. Hermoso apartamento con dos habitaciones en la zona más segura de Santa Cruz.

Hermoso apartamento con dos habitaciones en la zona más segura de Santa Cruz.
Santa Cruz de la Sierra
$46 nightly
The price is $46
Aug 27 - Aug 28
Hermoso apartamento con dos habitaciones en la zona más segura de Santa Cruz.

17. Experience comfort, luxury and tranquility

Experience comfort, luxury and tranquility
Santa Cruz
$95 nightly
The price is $95
Aug 29 - Aug 30
Experience comfort, luxury and tranquility

18. COMODO MONOAMBIENTE EN EQUIPETROL CON PISCINA EN CONDOMINIO!

COMODO MONOAMBIENTE EN EQUIPETROL CON PISCINA EN CONDOMINIO!
Santa Cruz de la Sierra
$67 nightly
The price is $67
Aug 15 - Aug 16
COMODO MONOAMBIENTE EN EQUIPETROL CON PISCINA EN CONDOMINIO!

19. Home Office / Smart / Swimming Pool / Coworking / Gym

Home Office / Smart / Swimming Pool / Coworking / Gym
Santa Cruz de la Sierra
Home Office / Smart / Swimming Pool / Coworking / Gym

20. Menacho Apartment - Mangales Blue - Norte

Menacho Apartment - Mangales Blue - Norte
Santa Cruz de la Sierra
$32 nightly
The price is $32
Aug 16 - Aug 17
Menacho Apartment - Mangales Blue - Norte
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

Discover your perfect Santa Cruz vacation rental with Expedia

How many vacation rentals are available in Santa Cruz?


Expedia has plenty of vacation rentals to choose from in and around  Santa Cruz, so you’re guaranteed to find the right one for you. 


How much is a vacation rental in Santa Cruz?


The selection of Santa Cruz vacation rentals we have selected for you start as low as $27 per night. Entering your travel dates in the search wizard you might find even better deals!


What type of vacation rental can I get in Santa Cruz?


Vacation rentals in Santa Cruz come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of Santa Cruz vacation rentals to suit everyone. 


Why should I choose a vacation rental in Santa Cruz?


Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A Santa Cruz vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. 


How do I find the best deal on a vacation rental in Santa Cruz?


Find vacation rentals in Santa Cruz by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in Santa Cruz.  


What amenities are available in a vacation rental in Santa Cruz?


The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in Santa Cruz vacation rentals designed to suit every budget and trip type.


When is the best time to stay in a vacation rental in Santa Cruz?   


Everytime is a great time to head to Santa Cruz! Staying in a Santa Cruz vacation rentals you will always find lots going on to keep you entertained. 


Why book a vacation rental with Expedia?


Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in Santa Cruz. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect Santa Cruz vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in Santa Cruz, you can save even more.


Can I cancel my vacation rental through Expedia?  


Yes, you can cancel or change your Santa Cruz vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.  


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