Title: Santa Cruz Resorts & Hotels with Spas from $56 - Fully Refundable Options - Expedia.com [Santa Cruz Travel Guide](https://expedia.com/Santa-Cruz.dx6297178)[Santa Cruz Hotels](https://expedia.com/Destinations-In-Santa-Cruz.d6297178.Hotel-Destinations)[Vacation Rentals in Santa Cruz](https://expedia.com/Destinations-In-Santa-Cruz.d6297178.Vacation-Rental-Destinations)[Santa Cruz Flights](https://expedia.com/Destinations-In-Santa-Cruz.d6297178.Flight-Destinations)[Car Rentals in Santa Cruz](https://expedia.com/Destinations-In-Santa-Cruz.d6297178.Car-Rental-Destinations)[Santa Cruz Vacations](https://expedia.com/Santa-Cruz.d6297178.Destination-Travel-Guides) ![San Lorenzo Cathedral which includes a church or cathedral, heritage architecture and heritage elements](https://images.trvl-media.com/place/6098830/d6a325c3-d504-4e1a-ab2b-0e430beefd40.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6098830/d6a325c3-d504-4e1a-ab2b-0e430beefd40.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in Santa Cruz ![San Lorenzo Cathedral showing a garden](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/115000/115563-Santa-Cruz.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Santa Cruz [](https://expedia.com/Santa-Cruz-Hotels-Spa-Hotel.0-0-d6053940-tSpaHotel.Travel-Guide-Filter-Hotels) ## Check availability on Santa Cruz Resorts & Hotels with Spas Tonight [Feb 18 - Feb 19](https://www.expedia.com/Hotel-Search?regionId=6297178&startDate=2026-02-18&endDate=2026-02-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 19 - Feb 20](https://www.expedia.com/Hotel-Search?regionId=6297178&startDate=2026-02-19&endDate=2026-02-20&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=6297178&startDate=2026-02-20&endDate=2026-02-22&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=6297178&startDate=2026-02-27&endDate=2026-03-01&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Cruz hotels with a spa ![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/0c12ee33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/9bf66d6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/ce43592e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/57e1e2e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel [](https://www.expedia.com/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) Santa Cruz 9.0/10 Wonderful (360 reviews) "Welcoming clean rooms, friendly staff, continental breakfast with natural drinks " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Victor $136 nightly $136 total Mar 14 - Mar 15 [](https://www.expedia.com/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) ![Massages](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/6b27e04a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/ffb227c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/d2cd08da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/9c172db1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Swissôtel Santa Cruz De La Sierra [](https://www.expedia.com/Santa-Cruz-Hotels-Swissotel-Santa-Cruz-De-La-Sierra.h60335614.Hotel-Information) Santa Cruz 9.2/10 Wonderful (83 reviews) "Beautiful hotel" ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Joanna $126 nightly $126 total Mar 5 - Mar 6 [](https://www.expedia.com/Santa-Cruz-Hotels-Swissotel-Santa-Cruz-De-La-Sierra.h60335614.Hotel-Information) ![Sauna, hot tub, steam room, massages](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/bb874c3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/98bdb5e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/97b153fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/baf4d4d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Cortez [](https://www.expedia.com/Santa-Cruz-Hotels-Hotel-Cortez.h13455822.Hotel-Information) Santa Cruz 9.2/10 Wonderful (124 reviews) "The staff and property are second to none! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cynthia $102 nightly $102 total Feb 20 - Feb 21 [](https://www.expedia.com/Santa-Cruz-Hotels-Hotel-Cortez.h13455822.Hotel-Information) ![Massage/treatment rooms](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/bdafe3cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/f930f88b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/02f3d22f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/e8e161c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Santa Cruz de la Sierra Hotel [](https://www.expedia.com/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) Santa Cruz 9.0/10 Wonderful (213 reviews) "Great hotel, food and location albeit a little expensive " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Reinaldo $115 nightly $115 total Feb 27 - Feb 28 [](https://www.expedia.com/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) ![Indoor spa tub](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/9d3a14b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/e96a8418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/0ffe84ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; garden views](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/01205665.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camino Real Hotel [](https://www.expedia.com/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) Santa Cruz 9.0/10 Wonderful (418 reviews) "Rooms were very clean and service was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JESUS $126 nightly $126 total Mar 15 - Mar 16 [](https://www.expedia.com/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/c21617f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor banquet area](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/fd471fdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/f5261f6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/630a5caa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sun Hotel [](https://www.expedia.com/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) Santa Cruz 8.2/10 Very Good (343 reviews) "Awesome place " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) John $97 nightly $97 total Feb 20 - Feb 21 [](https://www.expedia.com/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/18000000/17520000/17512600/17512569/71ca5d29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 1 Queen Bed, Bathtub | Minibar, in-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/18000000/17520000/17512600/17512569/d1ee5f39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/18000000/17520000/17512600/17512569/8d7c06c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/18000000/17520000/17512600/17512569/a80d15c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cosmopolitano Hotel Boutique [](https://www.expedia.com/Santa-Cruz-Hotels-Cosmopolitano-Hotel-Boutique.h17512569.Hotel-Information) Santa Cruz 9.2/10 Wonderful (125 reviews) "Wonderful staff, great food, big bathroom, just wonderful" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) John $71 nightly $71 total Mar 2 - Mar 3 [](https://www.expedia.com/Santa-Cruz-Hotels-Cosmopolitano-Hotel-Boutique.h17512569.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/0b114a98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/809a343e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/83c0e879.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/912c7493.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apart Hotel Toborochi [](https://www.expedia.com/Santa-Cruz-Hotels-Apart-Hotel-Toborochi.h10031984.Hotel-Information) Santa Cruz 8.8/10 Excellent (60 reviews) "Very comfortable and quiet place and very good location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luis $77 nightly $77 total Feb 28 - Mar 1 [](https://www.expedia.com/Santa-Cruz-Hotels-Apart-Hotel-Toborochi.h10031984.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/efaab5ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/a8bc5939.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 10:00 PM, free cabanas](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/78f237b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, minibar, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/b93ef62e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TRYP by Wyndham Santa Cruz [](https://www.expedia.com/Santa-Cruz-Hotels-TRYP-By-Wyndham-Santa-Cruz.h45617372.Hotel-Information) Santa Cruz 9.2/10 Wonderful (152 reviews) "Yes! Room was spotless. The staff are very patient and professional. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pluetina $99 nightly $99 total Feb 19 - Feb 20 [](https://www.expedia.com/Santa-Cruz-Hotels-TRYP-By-Wyndham-Santa-Cruz.h45617372.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/118000000/117980000/117976200/117976126/db53d748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/118000000/117980000/117976200/117976126/82e6695c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools](https://images.trvl-media.com/lodging/118000000/117980000/117976200/117976126/344828fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite | Down comforters, minibar, desk, laptop workspace](https://images.trvl-media.com/lodging/118000000/117980000/117976200/117976126/dd7ea04d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Prince Hotel [](https://www.expedia.com/Santa-Cruz-Hotels-Prince-Hotel.h117976126.Hotel-Information) Santa Cruz $56 nightly $56 total Feb 19 - Feb 20 [](https://www.expedia.com/Santa-Cruz-Hotels-Prince-Hotel.h117976126.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-04&endDate=2026-03-05®ionId=6297178&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=AFFINITY_SPRING_PROMO_6297178) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Santa-Cruz-Spa-Hotel.0-0-d6297178-tSpaHotel.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Santa-Cruz-Spa-Hotel.0-0-d6297178-tSpaHotel.Hotel-Filter-Destinations) ## Top Santa Cruz Hotel Reviews ![Hampton by Hilton Santa Cruz/Equipetrol, Bolivia](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/65fab765_y.jpg) ### Hampton by Hilton Santa Cruz/Equipetrol, Bolivia 10/10 Excellent "Convenient location clean rooms good breakfast with a view " [](https://expedia.com/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) ![Ibis Santa Cruz DE LA Sierra](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/53c67151_y.jpg) ### Ibis Santa Cruz DE LA Sierra 10/10 Excellent "Nice place" [](https://expedia.com/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) ![Delfines Collection Hotel By Mercure](https://images.trvl-media.com/lodging/91000000/90310000/90301900/90301892/fd3e0846_y.jpg) ### Delfines Collection Hotel By Mercure 10/10 Excellent "Rooms are always spotless good breakfasts rooftop pool with decent view " [](https://expedia.com/Santa-Cruz-Hotels-Delfines-Collection-Hotel-By-Mercure.h90301892.Hotel-Information) ![Chairú Eco Hotel](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/a88a9ace_y.jpg) ### Chairú Eco Hotel 10/10 Excellent "Staff was very courteous. They went above & beyond. Location was great!" [](https://expedia.com/Santa-Cruz-Hotels-Chairu-Eco-Hotel.h82389693.Hotel-Information) ![Camino Real Hotel](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/e96a8418_y.jpg) ### Camino Real Hotel 10/10 Excellent "Spotless, large and comfortable room was well maintained. Friendly and helpful staff. Delicious breakfast buffet. Location is near excellent shopping and dining options." [](https://expedia.com/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) ![Sun Hotel](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/d021f216_y.jpg) ### Sun Hotel 10/10 Excellent "Awesome place " [](https://expedia.com/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) ![Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/bb34bb1f_y.jpg) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel 10/10 Excellent "Welcoming clean rooms, friendly staff, continental breakfast with natural drinks " [](https://expedia.com/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) ![HOTEL OSHO](https://images.trvl-media.com/lodging/76000000/75260000/75254900/75254801/286f65b1_y.jpg) ### HOTEL OSHO 10/10 Excellent "Room was great and staff were very accommodating!" [](https://expedia.com/Santa-Cruz-Hotels-HOTEL-OSHO.h75254801.Hotel-Information) ![TRYP by Wyndham Santa Cruz](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/78f237b9_y.jpg) ### TRYP by Wyndham Santa Cruz 10/10 Excellent "Yes! Room was spotless. The staff are very patient and professional. " [](https://expedia.com/Santa-Cruz-Hotels-TRYP-By-Wyndham-Santa-Cruz.h45617372.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [Extended Stay Hotels in Santa Cruz ](https://www.expedia.com/Santa-Cruz-Hotels-Extended-Stay-Hotels.0-0-d6053940-tExtendedStayHotels.Travel-Guide-Filter-Hotels) - [Casino Hotels in Santa Cruz ](https://www.expedia.com/Santa-Cruz-Hotels-Casino-Hotel.0-0-d6053940-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Santa Cruz ](https://www.expedia.com/Santa-Cruz-Hotels-Hotels-With-Hot-Tubs.0-0-d6053940-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Santa Cruz ](https://www.expedia.com/Santa-Cruz-Hotels-Cheap-Hotels.0-0-d6053940-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels with Free Airport Shuttle in Santa Cruz ](https://www.expedia.com/Santa-Cruz-Hotels-Hotels-With-Free-Airport-Shuttle.0-0-d6053940-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in Santa Cruz ](https://www.expedia.com/Santa-Cruz-Hotels-Adults-Only-Resorts.0-0-d6053940-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - 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