Resorts & Hotels with Spas in Santa Cruz from $31
Upfront pricingOur total price for your stay includes taxes and fees
Treat yourselfSave 10% or more on over 100,000 hotels worldwide with Member Prices
Be pickySearch almost a million properties worldwide
Check availability on Santa Cruz Resorts & Hotels with Spas
Our top choices for Santa Cruz hotels with a spa
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio HotelSanta Cruz
9.0 out of 10, Wonderful, (389 reviews)
- Rejuvenating sanctuary with 5 treatment rooms offers hydrotherapy and aromatherapy at this Santa Cruz hotel spa.
$127 nightly
The price is $127
Jul 26 - Jul 27
9.2 out of 10, Wonderful, (88 reviews)
- Immerse in a tranquil spa sanctuary with massage treatments, sauna sessions, and poolside relaxation at this luxury hotel in Santa Cruz.
$101 nightly
The price is $101
Aug 4 - Aug 5
9.2 out of 10, Wonderful, (146 reviews)
- Unwind in this hotel's full-service spa with sauna, steam room, and hot tub, while enjoying a beautiful garden and outdoor pool.
$122 nightly
The price is $122
Jul 24 - Jul 25
9.0 out of 10, Wonderful, (239 reviews)
- Tranquil spa sanctuary with rooftop garden offers daily massages and outdoor pool in bustling business district.
$106 nightly
The price is $106
Jul 24 - Jul 25
9.0 out of 10, Wonderful, (433 reviews)
- Relax in opulent surroundings with a full-service spa, indoor and outdoor pools with swim-up bar.
$145 nightly
The price is $145
Aug 4 - Aug 5
9.2 out of 10, Wonderful, (135 reviews)
$91 nightly
The price is $91
Jul 30 - Jul 31
8.8 out of 10, Excellent, (60 reviews)
- Revitalize with indulgent massages and poolside relaxation at this tranquil aparthotel with garden sanctuary.
$135 nightly
The price is $135
Jul 21 - Jul 22
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Santa Cruz Hotel Reviews
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
10/10 Excellent
Explore a world of travel with Expedia
- Hilton Hotels in Santa Cruz
- All-Inclusive Resorts in Santa Cruz
- Extended Stay Hotels in Santa Cruz
- Hotels with a Gym in Santa Cruz
- Adults Only Resorts & in Santa Cruz
- Hotels with Bars in Santa Cruz
- Rainforest & Jungle Hotels in Santa Cruz
- Luxury Hotels in Santa Cruz
- Hotels with Laundry Facilities in Santa Cruz
- Hotels with Free Wifi in Santa Cruz
- Hotels with Kitchenettes in Santa Cruz
- Resorts & Hotels with Spas in Santa Cruz
- Romantic Hotels in Santa Cruz
- Hotels with Hot Tubs in Santa Cruz
- Business Hotels in Santa Cruz
- Hotels with Childcare in Santa Cruz
- Hotels with Free Airport Shuttle in La Guardia
- Hotels with an Indoor Pool in Santa Cruz
- Yha Hotels in Santa Cruz
- 4 Star Hotels in Roboré
- Waterpark Hotels in Santa Cruz
- Hotels with Balconies in Santa Cruz
- Hotel Wedding Venues Hotels in Santa Cruz
- Independent Hotels in Estancia Aguas Calientes
- Casino Hotels in Santa Cruz
- Hotels with Connecting Rooms in Santa Cruz
- Hotels with a Pool in Santa Cruz
- Historic Hotels in Santa Cruz
- Pet-Friendly Hotels in Santa Cruz
- 4 Star Hotels in Santa Cruz
- Cheap Hotels in Santa Cruz
- Safari Tentalow in Santa Cruz
- San Jose de Chiquitos Hotels
- Hotels with a Pool in Samaipata
- Hotels with Suites in Santa Cruz
- Best Western Hotels in Santa Cruz
- Gay friendly Hotels in Santa Cruz
- Buena Vista Hotels
- 3 Star Hotels in Warnes
- Santa Cruz Hotels
- Samaipata Hotels
- Apartments in Santa Cruz
- Hotels with a Swim-up Bar in Santa Cruz
- Hotels with Restaurants in Santa Cruz
- Beach Hotels in Santa Cruz
- Pet-Friendly Hotels in Samaipata
- Luxury Hotels in Samaipata
- Hostels in Santa Cruz
- Hotels on the River in Santa Cruz
- Boutique Hotels in Santa Cruz
- Golf Hotels in Colinas del Urubo
- Hotel with a Concierge Hotels in Santa Cruz
- Where to stay in Buena Vista
- Visit La Guardia
- Colinas del Urubo Vacations
- Santa Cruz Vacations
- La Guardia Vacations
- Visit Santa Cruz
- Visit Concepcion
- Visit El Torno
- Visit Camiri
- San Ignacio de Velasco Vacations
- Visit Samaipata
- Visit Roboré
- Visit Puerto Quijarro
- Visit Chochis
- Visit Colinas del Urubo
- Visit Buena Vista
- Suv Car Rentals in Santa Cruz
- Convertible Car Rentals in Santa Cruz
- Europcar Rental Cars in Santa Cruz
- Car rental Puerto Quijarro
- Car rental Puerto Suarez
- Hertz Rental Cars in Santa Cruz
- Luxury Car Rentals in Santa Cruz
- Car rental Samaipata
- Enterprise Rental Cars in Santa Cruz
- Ace Rental Cars in Santa Cruz
- Car rental Santa Cruz