A red train on tracks, palm trees, and modern buildings.

Central San Diego Vacation Rentals

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Check prices for these dates

In two weeks
Oct 9 - Oct 11
In two months
Nov 20 - Nov 22
In three months
Dec 18 - Dec 20
In four months
Jan 15 - Jan 17

Our top choices for Central San Diego vacation rentals

A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.

1. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (212 reviews)
"Receptionist was super nice and super helpful. The location was perfect. Everything was super close. Loved the room."
United States
Victor
$157 nightly
The price is $177
Oct 13 - Oct 14
Total with taxes and fees
City24 Hotel Little Italy Mission Hills
A spacious lobby with a sofa, chairs, a bookshelf, and a large window with a view of greenery.

2. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (473 reviews)
"It's good hotel for small day 1 to 3 nights no more then that due to the size of the room."
Canada
patrick
$97 nightly
The price is $110
Sep 29 - Sep 30
Total with taxes and fees
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
A high-rise hotel with multiple floors, a prominent sign at the top, and a well-lit facade.

3. Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,220 reviews)
"Great for traveling families."
United States
Veronica Dangerfield
$169 nightly
The price is $196
Sep 28 - Sep 29
Total with taxes and fees
Marriott Vacation Club®, San Diego
A spacious living area with a blue sofa, a glass coffee table, and a staircase leading to an upper level.

4. Winners Circle Solana Beach Del Mar Resort

Winners Circle Solana Beach Del Mar Resort
2.5 star property
Solana Beach
9.4 out of 10, Exceptional, (382 reviews)
"Great location and very nice property!"
United States
Diane
$191 nightly
The price is $216
Sep 28 - Sep 29
Total with taxes and fees
Winners Circle Solana Beach Del Mar Resort
A modern lobby with a green sofa, a wooden accent wall, and a large plant.

5. Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel
2.5 star property
Downtown San Diego
8.4 out of 10, Very good, (322 reviews)
"great stay"
United States
alex
$108 nightly
The price is $124
Sep 29 - Sep 30
Total with taxes and fees
Little Italy Inn - Limited Service Apart Hotel

6. Riviera Oaks Resort by Coolvacay

Riviera Oaks Resort by Coolvacay
3.0 star property
San Diego Country Estates
9.6 out of 10, Exceptional, (1,080 reviews)
"best place to relax, nice people"
United States
BO
$123 nightly
The price is $133
Sep 28 - Sep 29
Total with taxes and fees
Riviera Oaks Resort by Coolvacay
A rooftop pool with lounge chairs and a city skyline in the background.

7. Kasa Little Italy San Diego

Kasa Little Italy San Diego
4.5 star property
Downtown San Diego
9.6 out of 10, Exceptional, (538 reviews)
"Perfect location, great pool, beds were comfy. No complaints"
United States
Jeremy
$271 nightly
The price is $308
Oct 26 - Oct 27
Total with taxes and fees
Kasa Little Italy San Diego
A beach with a hotel in the background.

8. Coronado Beach Resort

Coronado Beach Resort
3.0 star property
Historic Downtown Coronado
9.0 out of 10, Wonderful, (825 reviews)
"The staff was wonderful and they had get togethers in the lobby and activities!"
United States
Phyllis
$209 nightly
The price is $230
Oct 25 - Oct 26
Total with taxes and fees
Coronado Beach Resort
A coastal residential area with houses, a well-maintained lawn, and a view of the ocean.

9. Wave Crest Resort

Wave Crest Resort
3.0 star property
Del Mar
9.2 out of 10, Wonderful, (159 reviews)
"wow, this is the best place ever. I had an amazing vacation. The staff was most hospitable. easy parking. I could hear the ocean at night while I slept. makes for a heavenly sleep only a 5-minute walk to the beach, but you could see the ocean from the room."
United States
Erik
$251 nightly
The price is $280
Oct 25 - Oct 26
Total with taxes and fees
Wave Crest Resort
A well-maintained garden with various plants and a lawn, surrounded by multi-story buildings with balconies.

10. San Diego Country Estates

San Diego Country Estates
2.5 star property
San Diego Country Estates
9.4 out of 10, Exceptional, (302 reviews)
"Clean, comfy bed, kitchen a plus, helpful staff"
United States
MARQIA
$115 nightly
The price is $122
Sep 28 - Sep 29
Total with taxes and fees
San Diego Country Estates
A kitchen with wooden cabinets, a microwave, an oven, and a large window overlooking a balcony.

11. Mt. Nebo Oasis in La Mesa w/ Wraparound Deck

Mt. Nebo Oasis in La Mesa w/ Wraparound Deck
3.0 star property
Windsor Hills
$853 nightly
The price is $939
Oct 2 - Oct 3
Total with taxes and fees
Mt. Nebo Oasis in La Mesa w/ Wraparound Deck
A neatly made bed with white and gold bedding, two bedside tables with lamps, and three wall-mounted mirrors.

12. Kasa Gaslamp Quarter San Diego

Kasa Gaslamp Quarter San Diego
3.5 star property
Downtown San Diego
7.8 out of 10, Good, (231 reviews)
"Wonderful place!"
Canada
Eric
$125 nightly
The price is $142
Sep 29 - Sep 30
Total with taxes and fees
Kasa Gaslamp Quarter San Diego
A modern building with a unique architectural design, featuring a balcony and a wooden deck area.

13. 2BR Condo Steps to the Beach & Blvd-dog-friendly

2BR Condo Steps to the Beach & Blvd-dog-friendly
3.0 star property
Mission Beach
$609 nightly
The price is $686
Sep 28 - Sep 29
Total with taxes and fees
2BR Condo Steps to the Beach & Blvd-dog-friendly
A living room with a white sofa, two blue armchairs, a wooden coffee table, and a painting on the wall.

14. < 2 Mi to Pacific Beach! Sunny San Diego Escape

< 2 Mi to Pacific Beach! Sunny San Diego Escape
3.0 star property
Pacific Beach
7.4 out of 10, Good, (3 reviews)
"Strategic location for beach, amusement parks and restaurants. Close to major freeways and airport. House has plenty of room across the three floors. Kids loved seeing the seaworld fireworks from the open air rooftop patio. This property has it all. Owner quickly addressed any of our questions and needs. "
United States
Thomas
$687 nightly
The price is $775
Sep 28 - Sep 29
Total with taxes and fees
< 2 Mi to Pacific Beach! Sunny San Diego Escape
A modern living room with a sofa, a TV, a floor lamp, and a large window offering a city view.

15. Rooftop w/ Views: Modern Little Italy Townhome

Rooftop w/ Views: Modern Little Italy Townhome
3.5 star property
Downtown San Diego
10.0 out of 10, Exceptional, (1 review)
$577 nightly
The price is $656
Oct 14 - Oct 15
Total with taxes and fees
Rooftop w/ Views: Modern Little Italy Townhome
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Central San Diego Hotel Reviews

The Atwood Hotel San Diego - SeaWorld/Zoo

The Atwood Hotel San Diego - SeaWorld/Zoo

10/10 Excellent
"We enjoyed our stay here! Right when we checked in the staff was friendly. Our room was spacious & clean. The bathroom was on the smaller side that’s the only negative if I had to say one thing. The hotel circle area is always a good location. I definitely recommend for a family stay. We loved the liquor store too for the convenience."
Karina 2-night trip
Posted 3 hours ago
The Atwood Hotel San Diego - SeaWorld/Zoo

Find out more about Central San Diego

Everything you need to know about Central San Diego vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Central San Diego vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Central San Diego vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Central San Diego vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Central San Diego. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Central San Diego in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $110 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Central San Diego rentals

At Expedia, we put the best Central San Diego vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Central San Diego rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Central San Diego vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Central San Diego. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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