Central San Diego Vacation Rentals

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Check prices for these dates

In two weeks
May 8 - May 10
In two months
Jun 19 - Jun 21
In three months
Jul 17 - Jul 19
In four months
Aug 14 - Aug 16

Our top choices for Central San Diego vacation rentals

Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.8 out of 10, Exceptional, (141 reviews)
"Love the design and decor and the hotel is close to the airport ease of parking. With that being said, it can be a little loud outside but it was still a great stay overall."
United States
Rose
$181 nightly
The price is $204
Apr 26 - Apr 27
Total with taxes and fees
City24 Hotel Little Italy Mission Hills
Beach towels

Adorable 1 bedroom house 8 min from La Jolla!

Adorable 1 bedroom house 8 min from La Jolla!
Bay Ho
10.0 out of 10, Exceptional, (51 reviews)
"Sparkling clean, friendly host and thoughtful layout"
United States
Griff V.
$230 nightly
The price is $256
Apr 26 - Apr 27
Total with taxes and fees
Adorable 1 bedroom house 8 min from La Jolla!
Lobby sitting area

Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very Good, (348 reviews)
"I had a great stay here, it was quiet and the neighborhood is amazing. "
United States
Robert
$114 nightly
The price is $129
Apr 27 - Apr 28
Total with taxes and fees
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
TV

Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches

Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches
Mid-City
8.0 out of 10, Very Good, (2 reviews)
"Wir hatten eine tolle Zeit in San Diego und in der Wohnung. Die Kommunikation mit Rebecca hat super geklappt. Sie hat uns die nötigen Infos für den Check In zur rightigen Zeit gegeben und war während des Aufenthaltes sehr hilfsbereit. Die Wohnung ist für 4 Personen ausreichend groß und perfekt ausgestattet, inkl Waschmaschine und Trockner. Vor allem die Küche haben wir ausgiebig genutzt und haben sehr viel selbst gekocht. Es fehlten lediglich eine Schere und ein Gemüsemesser. Rebecca hat uns...
Germany
Hanna S.
$498 nightly
The price is $498
Apr 28 - Apr 29
Total with taxes and fees
Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches
Property grounds

Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay

Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
Old Town San Diego
10.0 out of 10, Exceptional, (279 reviews)
"We enjoyed our time in the back cottage. Everything we needed was available. We were able to just walk to so many sites and restaurants. Will definitely try to come back again! "
United States
Phillip
$206 nightly
The price is $229
Apr 27 - Apr 28
Total with taxes and fees
Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
Fridge, microwave, oven, stovetop

Beautiful Normal Heights Living

Beautiful Normal Heights Living
Mid-City
10.0 out of 10, Exceptional, (82 reviews)
"Great location, nice cozy place, had everything we needed. Would definitely stay again."
United States
Sheila S.
$286 nightly
The price is $318
Apr 26 - Apr 27
Total with taxes and fees
Beautiful Normal Heights Living
Interior

Art Gallery Family Home - Southern California Style - Excellent Location

Art Gallery Family Home - Southern California Style - Excellent Location
Linda Vista
9.8 out of 10, Exceptional, (28 reviews)
"Location and the views! The house is an easy drive to everything in San Diego. The backyard was perfect for our kids and you couldn’t beat the views. The host was very communicative and welcoming also. "
United States
Dustin B.
$472 nightly
The price is $525
Apr 28 - Apr 29
Total with taxes and fees
Art Gallery Family Home - Southern California Style - Excellent Location
Terrace/patio

Cozy 2-Bedroom Cottage Near Balboa Park

Cozy 2-Bedroom Cottage Near Balboa Park
Mid-City
9.6 out of 10, Exceptional, (5 reviews)
$270 nightly
The price is $300
Apr 27 - Apr 28
Total with taxes and fees
Cozy 2-Bedroom Cottage Near Balboa Park
Property grounds

Private Cozy Clean, close to EVERYTHING

Private Cozy Clean, close to EVERYTHING
Mid-City
9.8 out of 10, Exceptional, (62 reviews)
"Great stay! Host was responsive and house was tidy and comfortable. The yard adds an additional living space. "
United States
Helen P.
Private Cozy Clean, close to EVERYTHING
Property grounds

2 bd w/ yard in heart of Old Town-- WE LOVE PETS! Check our Insta @oldtownvacay

2 bd w/ yard in heart of Old Town-- WE LOVE PETS! Check our Insta @oldtownvacay
Old Town San Diego
10.0 out of 10, Exceptional, (212 reviews)
" The host greeted us when we got there. She is lovely. There are so many shops and restaurants walking distance and the place is nice and clean. We had a great stay, I would definitely stay again!"
United States
Deana
$191 nightly
The price is $213
May 5 - May 6
Total with taxes and fees
2 bd w/ yard in heart of Old Town-- WE LOVE PETS! Check our Insta @oldtownvacay
Beach nearby

Secluded, Charming and Unique! Spacious Apartment EXCELLENT Central Location

Secluded, Charming and Unique! Spacious Apartment EXCELLENT Central Location
Mission Valley
9.2 out of 10, Wonderful, (60 reviews)
"Great central location. The apartment has lots of character. It had the essentials for a week's stay with a family of 5 but that was with bed-sharing and couch sleeping, which is what we expected. I'd certainly stay again."
United States
Brandon
$286 nightly
The price is $318
Apr 28 - Apr 29
Total with taxes and fees
Secluded, Charming and Unique! Spacious Apartment EXCELLENT Central Location
Dining

2 bed, Just a few Minutes to Airport & Old Town, Great City Skyline Views

2 bed, Just a few Minutes to Airport & Old Town, Great City Skyline Views
Mission Hills
7.0 out of 10, Good, (13 reviews)
"Me and my girlfriend stayed here for a weekend to kind of just enjoy not having to be home for a weekend and staying here was very nice; the view from the living room and balcony was amazing, was close to all the hotspots in SD and just felt like a second home. I was a bit of a chaotic guest leading up to the check-in and that is because of my work but the host Daniel was very helpful and patient with my mistakes and I appreciate what he did for us."
United States
Nico E.
$367 nightly
The price is $408
Apr 27 - Apr 28
Total with taxes and fees
2 bed, Just a few Minutes to Airport & Old Town, Great City Skyline Views
1 bedroom, iron/ironing board, WiFi, bed sheets

Modern 1BR/1BA Getaway in Central San Diego – Walk to Zoo, Balboa Park & Dining

Modern 1BR/1BA Getaway in Central San Diego – Walk to Zoo, Balboa Park & Dining
University City
$285 nightly
The price is $317
May 4 - May 5
Total with taxes and fees
Modern 1BR/1BA Getaway in Central San Diego – Walk to Zoo, Balboa Park & Dining
Interior

Cozy 2Bed 1BA Bankers Hill Residence with Parking, no chores!

Cozy 2Bed 1BA Bankers Hill Residence with Parking, no chores!
Bankers Hill
9.4 out of 10, Exceptional, (46 reviews)
"Clean and cozy. "
United States
Jason B.
$392 nightly
The price is $436
Apr 26 - Apr 27
Total with taxes and fees
Cozy 2Bed 1BA Bankers Hill Residence with Parking, no chores!
Outdoor dining

Artistic + FastWi-Fi + Parking + Pets + EV Charging!

Artistic + FastWi-Fi + Parking + Pets + EV Charging!
North Park
9.8 out of 10, Exceptional, (19 reviews)
"My family of four had a wonderful week-long stay here! The apartment was clean, had everything we needed, and we appreciated the secured parking garage. The provided high chair and pack-n-play also worked very well for us. We loved being so close to San Diego's many attractions; it was easy to drive anywhere from this relatively central location. Our host was responsive, helpful, and made sure we had a great stay. We would not hesitate to book this again in the future!"
United States
Benjamin C.
$385 nightly
The price is $429
Apr 26 - Apr 27
Total with taxes and fees
Artistic + FastWi-Fi + Parking + Pets + EV Charging!
Smart TV, offices

1b1b Central Hillcrest, San Diego condo. Walkable neighborhood and central to SD

1b1b Central Hillcrest, San Diego condo. Walkable neighborhood and central to SD
Hillcrest
9.6 out of 10, Exceptional, (19 reviews)
"Great location to many desirable places like Zoo, La Holla, and downtown "
United States
Jean Pierre
$221 nightly
The price is $246
Apr 28 - Apr 29
Total with taxes and fees
1b1b Central Hillcrest, San Diego condo. Walkable neighborhood and central to SD
Private kitchen

Cozy Private Home, 10-min From DT, Beach & Parks

Cozy Private Home, 10-min From DT, Beach & Parks
Mid-City
8.2 out of 10, Very Good, (14 reviews)
"Our family stayed for spring break. We found that the location was perfect to be able to get anywhere we needed to go quite conveniently. The house was perfect for what we needed and we were always able to find a parking spot. "
United States
Leah S.
$238 nightly
The price is $265
Apr 27 - Apr 28
Total with taxes and fees
Cozy Private Home, 10-min From DT, Beach & Parks
Terrace/patio

✔Remote Work✔A/C✔200Mbps✔Kitchen✔Streaming

✔Remote Work✔A/C✔200Mbps✔Kitchen✔Streaming
University City
10.0 out of 10, Exceptional, (33 reviews)
"Great property, very well maintained & the hosts were wonderful. "
United States
Ryan B.
$511 nightly
The price is $569
Apr 26 - Apr 27
Total with taxes and fees
✔Remote Work✔A/C✔200Mbps✔Kitchen✔Streaming
Outdoor spa tub

San Diego Fun: Jacuzzi-Golf-PoolTable-GmRm!

San Diego Fun: Jacuzzi-Golf-PoolTable-GmRm!
Clairemont
8.6 out of 10, Excellent, (12 reviews)
"Great place to stay. Very clean and the area location was ideal. Easy access to stores and restaurants nearby. Plan to stay here next time when I am in San Diego."
United States
Rossana P.
$395 nightly
The price is $439
May 7 - May 8
Total with taxes and fees
San Diego Fun: Jacuzzi-Golf-PoolTable-GmRm!
Interior

North Park Penthouse~King Beds~Workspaces~Parking~Near Zoo, Balboa Park!

North Park Penthouse~King Beds~Workspaces~Parking~Near Zoo, Balboa Park!
San Diego
9.2 out of 10, Wonderful, (9 reviews)
"Location was great. Perfect place for the family on our weekend trip."
United States
Gabriel
North Park Penthouse~King Beds~Workspaces~Parking~Near Zoo, Balboa Park!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Central San Diego Hotel Reviews

Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area

Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area

10/10 Excellent
"We stayed a week at this location . The staff was so friendly and helpful. The property was clean and easy access to everything in San Diego. I would stay there again"
Duwayne 5-night trip
Posted 1 hour ago
Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area

Find out more about Central San Diego

Everything you need to know about Central San Diego vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Central San Diego vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Central San Diego vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Central San Diego vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Central San Diego. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Central San Diego in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $129 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Central San Diego rentals

At Expedia, we put the best Central San Diego vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Central San Diego rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Central San Diego vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Central San Diego. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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