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Central San Diego Vacation Rentals

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Check prices for these dates

In two weeks
Sep 11 - Sep 13
In two months
Oct 23 - Oct 25
In three months
Nov 20 - Nov 22
In four months
Dec 18 - Dec 20

Our top choices for Central San Diego vacation rentals

Lobby sitting area

1. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very Good, (441 reviews)
"Room was perfect for our short trip. Clean room and friendly staff."
United States
Diana
$99 nightly
The price is $112
Sep 7 - Sep 8
Total with taxes and fees
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio

2. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (191 reviews)
"Enjoyed my stay! Clean spacious room and friendly staff."
United States
omokayode
$177 nightly
The price is $200
Sep 1 - Sep 2
Total with taxes and fees
City24 Hotel Little Italy Mission Hills
Exterior

3. San Diego Centralized Retreat

San Diego Centralized Retreat
Birdland
10.0 out of 10, Exceptional, (1 review)
"A beautiful apartment! Definitely going to reserve that location for more days next time. Kitchen is great and loved having upstairs-downstairs for separate spaces when one of us was working"
United States
Margaret C.
$201 nightly
The price is $212
Aug 26 - Aug 27
Total with taxes and fees
San Diego Centralized Retreat
Living area

4. Relaxing Retreat in North Park – 3943

Relaxing Retreat in North Park – 3943
North Park
10.0 out of 10, Exceptional, (1 review)
"The stay and experience there and with the owner was absolutely great. The place was cozy and clean. He was on the spot with all needs that we're needing to be met. "
United States
Jamall D.
$236 nightly
The price is $246
Aug 26 - Aug 27
Total with taxes and fees
Relaxing Retreat in North Park – 3943
Property grounds

5. Close to Airport | Walk to Restaurants

Close to Airport | Walk to Restaurants
Middletown
8.8 out of 10, Excellent, (3 reviews)
"Exactly as advertised. Door to bathroom being shutters was an interesting decision but apart from that it was clean and in good condition and generally a good place to stay. Great location, close to a row of restaurants and can see the taxiways for San Diego international."
United States
Yan W.
$296 nightly
The price is $332
Aug 27 - Aug 28
Total with taxes and fees
Close to Airport | Walk to Restaurants
Dining

6. Private Cozy Clean, close to EVERYTHING

Private Cozy Clean, close to EVERYTHING
Mid-City
9.8 out of 10, Exceptional, (71 reviews)
"Location was perfect for daily outings in San Diego. Would stay again. "
United States
Caitlin M.
$304 nightly
The price is $339
Sep 21 - Sep 22
Total with taxes and fees
Private Cozy Clean, close to EVERYTHING
Dining

7. Explore San Diego from a Central Location with Canyon Views

Explore San Diego from a Central Location with Canyon Views
North Park
10.0 out of 10, Exceptional, (5 reviews)
"Check in was nice and easy. Hosts were very responsive and helped out with a small supply issue in minutes. The space was clean and organized and made for a great stay on my work trip."
United States
Corey M.
$271 nightly
The price is $301
Aug 26 - Aug 27
Total with taxes and fees
Explore San Diego from a Central Location with Canyon Views
Property grounds

8. Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay

Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
Old Town San Diego
10.0 out of 10, Exceptional, (301 reviews)
"Super cute, private little cottage in a great location. Loved the stay, very easy process and great host!"
United States
Ross
$181 nightly
The price is $201
Aug 31 - Sep 1
Total with taxes and fees
Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
Beach

9. Adorable 1 bedroom house 8 min from La Jolla!

Adorable 1 bedroom house 8 min from La Jolla!
Bay Ho
10.0 out of 10, Exceptional, (57 reviews)
"Fantastic place and host especially for the price"
United States
Fayaz J.
$285 nightly
The price is $317
Aug 26 - Aug 27
Total with taxes and fees
Adorable 1 bedroom house 8 min from La Jolla!
Living area

10. Central Mission Hills Condo with Spectacular Views

Central Mission Hills Condo with Spectacular Views
Mission Hills
9.8 out of 10, Exceptional, (6 reviews)
"Very beautiful and well maintained property. Plenty of space and everything you need for the stay."
United States
Katherine K.
$321 nightly
The price is $356
Sep 1 - Sep 2
Total with taxes and fees
Central Mission Hills Condo with Spectacular Views
Living area

11. Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches

Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches
Mid-City
8.0 out of 10, Very Good, (4 reviews)
"We thoroughly appreciated the communications provided by the host. Initially had a few teething issues, with the keylock code not working, and a smell in the bedroom and the living area, but this was rectified and a cleaning crew came in twice for it. Place is perfectly situated (with car use) but a bit less so if on foot, or public transportation. The laundry in the shed and the kitchen are always welcome especially as our booking was over 2 weeks long! Thanks again for a suitable stay for us!"
United States
Carlo Luis
$461 nightly
The price is $461
Sep 1 - Sep 2
Total with taxes and fees
Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches
Living area

12. Modern Hideaway in North Park - 3941

Modern Hideaway in North Park - 3941
North Park
10.0 out of 10, Exceptional, (2 reviews)
"Cozy spot in a convenient location. Easy fast communication with the host. Did not rent/use a car this trip, but there is a garage behind the unit with a parking space that seems vital if you’re planning to stay in this area with a vehicle."
United States
William K.
$236 nightly
The price is $246
Sep 1 - Sep 2
Total with taxes and fees
Modern Hideaway in North Park - 3941
Room

13. Stylish & Comfy Gem: Walk To Everything ~ Parking!

Stylish & Comfy Gem: Walk To Everything ~ Parking!
North Park
9.0 out of 10, Wonderful, (2 reviews)
"Great stay, very tight parking spot though!"
United States
Alana M.
$352 nightly
The price is $352
Aug 26 - Aug 27
Total with taxes and fees
Stylish & Comfy Gem: Walk To Everything ~ Parking!
Room

14. Luxury San Diego 1BR with Premium Conveniences

Luxury San Diego 1BR with Premium Conveniences
Mid-City
$248 nightly
The price is $276
Sep 9 - Sep 10
Total with taxes and fees
Luxury San Diego 1BR with Premium Conveniences
Interior

15. Classic Hillcrest Escape – Near University Heights, Balboa Park & Zoo

Classic Hillcrest Escape – Near University Heights, Balboa Park & Zoo
University Heights
10.0 out of 10, Exceptional, (3 reviews)
"The host was great. The location was great. The place was very clean, and had all the basics."
United States
Kevin A.
$346 nightly
The price is $385
Sep 8 - Sep 9
Total with taxes and fees
Classic Hillcrest Escape – Near University Heights, Balboa Park & Zoo
Beach

16. Secluded, Charming and Unique! Spacious Apartment EXCELLENT Central Location

Secluded, Charming and Unique! Spacious Apartment EXCELLENT Central Location
Mission Valley
9.2 out of 10, Wonderful, (66 reviews)
"My overall experience was excellent. The place is close by several restaurants and shops. The place was decent stay and spacious enough for 4-5 people. The host communicated outstanding and open to be available with any questions or concerns which was appreciated. "
United States
Michelle A.
$345 nightly
The price is $384
Sep 3 - Sep 4
Total with taxes and fees
Secluded, Charming and Unique! Spacious Apartment EXCELLENT Central Location
Terrace/patio

17. Cozy 2-Bedroom Cottage Near Balboa Park

Cozy 2-Bedroom Cottage Near Balboa Park
Mid-City
8.8 out of 10, Excellent, (11 reviews)
"The place was as advertised. Comfortable and good privacy in an area that at first glance, didn’t seem like it would have any"
United States
Steve F.
$259 nightly
The price is $288
Aug 26 - Aug 27
Total with taxes and fees
Cozy 2-Bedroom Cottage Near Balboa Park
Room

18. Private Entrance With Crisp Sheets And A Cozy Grotto Shower

Private Entrance With Crisp Sheets And A Cozy Grotto Shower
Mid-City
$128 nightly
The price is $142
Aug 31 - Sep 1
Total with taxes and fees
Private Entrance With Crisp Sheets And A Cozy Grotto Shower
Terrace/patio

19. Wellness Oasis—Cold Plunge, Hot tub, Sauna, AC

Wellness Oasis—Cold Plunge, Hot tub, Sauna, AC
Golden Hill
10.0 out of 10, Exceptional, (17 reviews)
"We really enjoyed our stay! Place is clean and just so calming with all the fun amenities!! Would certainly come back and stay here any time! Chelsea is very approachable and very nice."
United States
Muhib H.
$1,263 nightly
The price is $1,283
Sep 1 - Sep 2
Total with taxes and fees
Wellness Oasis—Cold Plunge, Hot tub, Sauna, AC
Living area

20. Hideaway in the heart of San Diego!

Hideaway in the heart of San Diego!
Mid-City
10.0 out of 10, Exceptional, (8 reviews)
"Very pet friendly. Parking right behind the house. Overall excellent stay."
United States
Lisa S.
$258 nightly
The price is $287
Sep 2 - Sep 3
Total with taxes and fees
Hideaway in the heart of San Diego!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Central San Diego Hotel Reviews

Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla

8/10 Good
"It was overall good."
AISHA 6-night trip
Posted 3 hours ago
Embassy Suites by Hilton San Diego La Jolla

Find out more about Central San Diego

Everything you need to know about Central San Diego vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Central San Diego vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Central San Diego vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Central San Diego vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Central San Diego. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Central San Diego in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $112 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Central San Diego rentals

At Expedia, we put the best Central San Diego vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Central San Diego rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Central San Diego vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Central San Diego. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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