Central San Diego Vacation Rentals from $115: Search Short-Term Rentals

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Our top choices for Central San Diego vacation rentals

A spacious lobby with a sofa, chairs, a bookshelf, and a large window with a view of greenery.

1. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Hillcrest

Josh

$102 nightly

Oct 26 - Oct 27

Total with taxes and fees

A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.

2. City24 Hotel Little Italy Mission Hills

Middletown

Donavin

$157 nightly

Nov 2 - Nov 3

Total with taxes and fees

A modern fireplace with logs, surrounded by rustic decor including a potted plant and vases.

3. Large Group Wellness Retreat w Spa & Gym

University City

$1,501 nightly

Nov 13 - Nov 14

Total with taxes and fees

A high-rise hotel with multiple floors, a prominent sign at the top, and a well-lit facade.

4. Marriott Vacation Club®, San Diego

Downtown San Diego

Veronica Dangerfield

$144 nightly

Nov 9 - Nov 10

Total with taxes and fees

A spacious living area with a blue sofa, a glass coffee table, and a staircase leading to an upper level.

5. Winners Circle Solana Beach Del Mar Resort

Solana Beach

Shelly

$167 nightly

Nov 25 - Nov 26

Total with taxes and fees

6. Coronado Beach Resort

Historic Downtown Coronado

Javier

$199 nightly

Nov 15 - Nov 16

Total with taxes and fees

A modern lobby with a green sofa, a wooden accent wall, and a large plant.

7. Little Italy Inn - Limited Service Apart Hotel

Downtown San Diego

alex

$108 nightly

Oct 26 - Oct 27

Total with taxes and fees

A rooftop pool with lounge chairs and a city skyline in the background.

8. Kasa Little Italy San Diego

Downtown San Diego

Nirmeen

$268 nightly

Oct 27 - Oct 28

Total with taxes and fees

A coastal residential area with houses, a well-maintained lawn, and a view of the ocean.

9. Wave Crest Resort

Del Mar

Erik

$240 nightly

Nov 1 - Nov 2

Total with taxes and fees

10. Riviera Oaks Resort by Coolvacay

San Diego Country Estates

Kristin

$104 nightly

Oct 26 - Oct 27

Total with taxes and fees

A modern building with a unique architectural design, featuring a balcony and a wooden deck area.

11. Stroll to Shore + Mission Blvd: Dog-friendly Home

Mission Beach

$530 nightly

Oct 26 - Oct 27

Total with taxes and fees

A well-maintained garden with various plants and a lawn, surrounded by multi-story buildings with balconies.

12. San Diego Country Estates

San Diego Country Estates

Charles

$121 nightly

Oct 26 - Oct 27

Total with taxes and fees

A neatly made bed with white and gold bedding, two bedside tables with lamps, and three wall-mounted mirrors.

13. Kasa Gaslamp Quarter San Diego

Downtown San Diego

Eric

$105 nightly

Nov 23 - Nov 24

Total with taxes and fees

A living room with a white sofa, two blue armchairs, a wooden coffee table, and a painting on the wall.

14. < 2 Mi to Pacific Beach! Sunny San Diego Escape

Pacific Beach

Thomas

$676 nightly

Nov 15 - Nov 16

Total with taxes and fees

A modern living room with a grey sofa, a white coffee table, and a potted plant.

15. Rooftop w/ Views: Modern Little Italy Townhome

Downtown San Diego

$577 nightly

Nov 22 - Nov 23

Total with taxes and fees

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Top Central San Diego Hotel Reviews

Country Inn & Suites by Radisson, San Diego North, CA

10/10 Excellent

"Friendly staff. 10 of 10 recommended."

Ramada Suites by Wyndham San Diego/Hotel Circle Area

8/10 Good

"The hotel itself is old and dated; very much in need of an overhaul. Very no frills; that being said. The room was clean; the bed and pillows comfy. The small fridge kept everything cold. No lotions in the bathroom. Other guests complained of odor; our room was fresh. There was an interior hallway that had doors that remained open to the outside rooms on all the floors. That hallway had a musty smell. Again; no frills. The staff was helpful and very friendly. The breakfast is basic chain hotel fare. Waffles, eggs, sausage/ bacon. Bagels; little muffins; bread and cereal. Just the basics. My husband and I stayed a week; it was quiet; couldn't hear the freeway noise. The air conditioner worked very well. The pool was clean; we didn't use it but other guests did. The hot tub wasn't working. Parking was ample. 14.00 a night is a bit steep. Considering we only needed the room for sleep; we couldn't beat the price. That left us with more for attractions and gas."

Best Western Seven Seas

10/10 Excellent

"We like the size of the room and the parking near our door. The plants outside were very pretty and well cared for. Everything was wonderful and clean but would have enjoyed the TV more if there was a paper to show how to use the for older people to understand the TV better. But everything was the best."

Find out more about Central San Diego

Everything you need to know about Central San Diego vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Central San Diego vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Central San Diego vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Central San Diego vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Central San Diego. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Central San Diego in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $115 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Central San Diego rentals

At Expedia, we put the best Central San Diego vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Central San Diego rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Central San Diego vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Central San Diego. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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Check prices for these dates

Our top choices for Central San Diego vacation rentals

1. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

2. City24 Hotel Little Italy Mission Hills

3. Large Group Wellness Retreat w Spa & Gym

4. Marriott Vacation Club®, San Diego

5. Winners Circle Solana Beach Del Mar Resort

6. Coronado Beach Resort

7. Little Italy Inn - Limited Service Apart Hotel

8. Kasa Little Italy San Diego

9. Wave Crest Resort

10. Riviera Oaks Resort by Coolvacay

11. Stroll to Shore + Mission Blvd: Dog-friendly Home

12. San Diego Country Estates

13. Kasa Gaslamp Quarter San Diego

14. < 2 Mi to Pacific Beach! Sunny San Diego Escape

15. Rooftop w/ Views: Modern Little Italy Townhome

Find vacation rentals that suit your style

Top Central San Diego Hotel Reviews

Country Inn & Suites by Radisson, San Diego North, CA

Ramada Suites by Wyndham San Diego/Hotel Circle Area

Best Western Seven Seas

Hilton San Diego Mission Valley

The Atwood Hotel San Diego - SeaWorld/Zoo

Find out more about Central San Diego

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