Central San Diego Vacation Rentals

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Vacation Rentals in Central San Diego

Aparthotel in Hillcrest

2.5 star property
8.4 out of 10, Very Good, (259)
"Overall good place."
United States
Isaac
Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Aparthotel in Middletown

4.5 star property
9.6 out of 10, Exceptional, (101)
"Staff was very attentive and the building was wonderful. The only reason I didn't rate 5 stars is it can be quite loud being across the street from the airport. "
United States
Michael
$165 nightly
The price is $186
Dec 11 - Dec 12
Total with taxes and fees
City24 Hotel Little Italy Mission Hills

Vacation Home in Clairemont

9.8 out of 10, Exceptional, (156)
"Great value great location."
United States
Michael D.
Family Getaway ★ Pool & Hot-tub ★ HVAC ★ 4BD & Central

Vacation Home in Mid-City

10.0 out of 10, Exceptional, (45)
"The house was perfect for our family vacation! Very close to the zoo, Balboa Park and other great San Diego spots. Will definitely stay again"
United States
Jessica C.
Fox Canyon Hideaway-San Diego

Vacation Home in Mid-City

2.0 star property
10.0 out of 10, Exceptional, (69)
"Great dog-friendly location with lots of great local dining options. Welcoming hosts, nice coffee, very comfortable home!"
United States
Erika Van Bramer Mallory R.
$286 nightly
The price is $318
Nov 30 - Dec 1
Total with taxes and fees
Beautiful Normal Heights Living

Vacation Home in North Park

5.4 out of 10, (12)
"This tri-level home was just right for our family of five. It was clean, the beds were very comfortable and we got to park in the garage. The neighborhood was quiet and the location was within 20 minutes of all our activities for the week. Our host was easy to work with. Definitely recommend :)"
United States
Tina M.
$400 nightly
The price is $445
Dec 2 - Dec 3
Total with taxes and fees
Spanish Style 3 Story House, Best Location in SD. Views of North Park, W/ AC.

Vacation Home in Bankers Hill

9.4 out of 10, Exceptional, (60)
"Great house for my brother's and I to enjoy San Diego with our families."
United States
David W.
*Charming* Family & Couples Friendly 4 BR ENTIRE HOUSE

Vacation Home in Clairemont

10.0 out of 10, Exceptional, (56)
"Todds place was really nice, and very spacious. My friends and I enjoyed our stay at the house. "
United States
jazmin A.
Newly Renovated Modern Home w/ Pool, Jacuzzi, Pool Table - Close to All

Vacation Home in Bay Ho

9.8 out of 10, Exceptional, (68)
"We were a family of 9, including a baby, that stayed for 3 nights. This home is as described with a well-maintained pool and hot tub, and multiple pool toys, that we enjoyed! The neighborhood is quiet and peaceful. It is a drive to get to local shops, restaurants, and the beach. Andrea and Tim were quick to respond to any questions and needs. Thank you for a relaxing stay!"
United States
Judy C.
Palisades By the Bay Whole House Rental

Cottage in Old Town San Diego

10.0 out of 10, Exceptional, (268)
"We enjoyed our stay. The place was perfect and there was even a dog bed, toys, and a water dish filled with water waiting for us when we got there. Within walking distance to lots of dog friendly restaurants and within a 10-15min drive to all the things we wanted to do in San Diego, including an off leash dog beach. Would stay here again."
United States
Michele S.
$217 nightly
The price is $241
Dec 1 - Dec 2
Total with taxes and fees
Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay

Apartment in Linda Vista

9.6 out of 10, Exceptional, (56)
"Great location and solid accommodations. Thank you Jimmy for a great stay!"
United States
Eric S.
The Hideaway of Silver Terrace

Vacation Home in Linda Vista

10.0 out of 10, Exceptional, (22)
"Great, HUGE property. Pictures don’t really do it justice. Nice location too."
United States
Frederick B.
San Diego Villa with pool, jacuzzi and sunset-views

Cottage in Bankers Hill

2.0 star property
9.2 out of 10, Wonderful, (5)
"Nice open living space. Clean linens and kitchen. Great space for a family! The home is close to the airport and freeway, and you can hear traffic, but it wasn't an issue as all. The kids loved watching the planes land."
United States
Katie Z.
Comfy 3bd / 2ba home steps from Little Italy

Vacation Home in Mira Mesa

9.8 out of 10, Exceptional, (37)
"Had an amazing stay"
United States
Danielle J.
Relaxing Sunny Diego Style & Working Remotely!

Apartment in Middletown

10.0 out of 10, Exceptional, (243)
"Overall very good place to stay. Close to downtown beach old town and airport. "
United States
H M.
Romantic Guest House, Spectacular Views, Close to everything , Private Hot Tub

Cottage in North Park

10.0 out of 10, Exceptional, (453)
"Great location for us."
United States
Geraldine B.
Charming cottage in North Park

Vacation Home in Serra Mesa

8.6 out of 10, Excellent, (18)
"Great for family fun. Location nesr beaches, downtown and balboa Park "
United States
Gregory H.
Entire home, Pool, Free Parking, WiFi, Pets are allowed

Vacation Home in Linda Vista

9.8 out of 10, Exceptional, (179)
"Nice place "
United States
Teresa B.
Family Game Room with Wet Bar, Pool Table/ Ping Pong Darts and more!

Condo in Hillcrest

9.4 out of 10, Exceptional, (14)
"Location was fantastic! Perfect size for 2 people needing a quick weekend getaway. Also, you won't be disappointed when getting a chance to meet Crispy the dog!"
United States
Erik W.
$221 nightly
The price is $246
Dec 9 - Dec 10
Total with taxes and fees
1b1b Central Hillcrest, San Diego condo. Walkable neighborhood and central to SD

Vacation Home in Mission Hills

9.4 out of 10, Exceptional, (211)
"Great location and great views. We enjoyed the house. "
United States
Mark S.
Luxury 5BD/4BA Mission Hills/Stunning Rooftop + Skyline Views
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Central San Diego Hotel Reviews

Find out more about Central San Diego

Everything you need to know about Central San Diego vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Central San Diego vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Central San Diego vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Central San Diego vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Central San Diego. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Central San Diego in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $186 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Central San Diego rentals

At Expedia, we put the best Central San Diego vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Central San Diego rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Central San Diego vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Central San Diego. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.