Top 10 Hotels in Isola (from $65) 2026 - Competitive Prices

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Our top choices for Isola hotels

A poolside area with two wooden lounge chairs and a clear view of the ocean.

An open door leading to a balcony with a view of the sea, a piano, and a chair.

An outdoor seating area with two chairs and a table, overlooking a coastal landscape with trees and a view of the sea.

A spacious living room with a large sectional sofa, a glass coffee table, and multiple windows offering a view of the outdoors.

1. Galatea e Giardino delle Esperidi apartments with pool by Wonderful Italy

Syracuse

$257 nightly

$280 total

Oct 22 - Oct 23

Total with taxes and fees

A coastal terrace with wicker furniture, striped umbrellas, and a rocky backdrop.

A swimming pool with lounge chairs and umbrellas, surrounded by buildings with a staircase and a view of the city skyline.

A grand staircase with marble steps and red carpet, flanked by wooden balustrades and potted plants, leading to a room with ornate decor and a chandelier.

A grand lobby with a central red seating area, a staircase, and a high ceiling with skylights.

2. Grand Hotel Villa Politi

Grottasanta

Michelle

$86 nightly

$98 total

Nov 3 - Nov 4

Total with taxes and fees

A historic building with ornate balconies, a grand entrance, and flags of the European Union and Italy.

A grand staircase with ornate metal railings and red carpeted steps leading to a balcony area with arched doorways and a checkered floor.

A buffet with various food items and condiments.

A spacious living room with a large sofa, two armchairs, a dining area with a table and chairs, and a kitchen in the background.

3. Grande Albergo Alfeo

Santa Lucia

Anna

$80 nightly

$91 total

Nov 1 - Nov 2

Total with taxes and fees

A poolside breakfast setup with a newspaper, fruit bowl, juice, and coffee.

A terrace with outdoor seating, a table with food and drinks, and potted plants.

A spacious living area with a modern design, featuring a sofa set, a coffee table, and a bookshelf.

A modern dining area with multiple tables and chairs, a kitchen in the background, and decorative plants.

4. Albatros Hotel

Syracuse

lynda

$84 nightly

$96 total

Oct 27 - Oct 28

Total with taxes and fees

A bakery display with various baked goods and a sign indicating apple and jam cake.

A hallway with a stone wall, a wooden door, and a purple-lit wall.

An outdoor patio area with seating and potted plants, under a night sky.

5. UNA Hotels One Siracusa Wellness & SPA

Grottasanta

Tanasha

$110 nightly

$126 total

Nov 3 - Nov 4

Total with taxes and fees

A stone wall with a small pool, two white pitchers, and a vase.

A restaurant with a long counter, glass display case with food, and seating area.

An outdoor seating area with a table, a blue vase, and a white umbrella.

A modern hotel room with a bed, a desk, and a chair. There are towels on the bed and a plant on the desk.

6. CinqueSuites Ortigia

Ortigia

Dongni

$83 nightly

$94 total

Nov 3 - Nov 4

Total with taxes and fees

A historic building with a central entrance, multiple balconies, and a large potted plant in front.

A spacious living area with a large mirror, a chandelier, and a fireplace. There are multiple seating options including a sofa and chairs.

A rooftop terrace with outdoor seating, a view of the sea, and parked cars.

An interior view of a restaurant with stone arches, wooden beams, and tables set for dining.

7. Algila' Ortigia Charme Hotel

Ortigia

Rachael

$193 nightly

$224 total

Oct 31 - Nov 1

Total with taxes and fees

An outdoor swimming pool with a wooden deck, surrounded by white umbrellas and lounge chairs.

A spacious restaurant with high wooden ceilings and large windows.

A reception desk with a framed picture on the wall, a potted plant, and a sign above the desk.

A hotel room with a bed, a TV mounted on the wall, and a window with curtains.

8. Mercure Siracusa Prometeo

Neapolis

Stephanie

$80 nightly

$103 total

Nov 3 - Nov 4

Total with taxes and fees

A hotel room with a large bed, a window with a view of buildings, a bedside table with a lamp, and a mirror on the wall.

A hotel entrance with a sign reading "Hotel Como" and three flags.

A view from a balcony overlooking a parking area with several cars, a yellow building with arched windows, and a clock tower.

A room with a large window overlooking a street and a building with a clock tower.

9. Hotel Como

Syracuse

Yinan

$57 nightly

$65 total

Nov 1 - Nov 2

Total with taxes and fees

A poolside setting with a person relaxing, a table with a drink and fruit, and a view of the pool and chairs in the background.

A multi-story hotel with a covered entrance, a well-maintained lawn, and a classic architectural style.

A pathway leading through a garden with large planters and tall conical lights.

A courtyard with tables set up for an event, surrounded by buildings with large windows and a well-lit exterior.

10. Hotel Parco delle Fontane

Tiche

Tony

$119 nightly

$136 total

Nov 4 - Nov 5

Total with taxes and fees

A balcony with a view of the sea, featuring a metal railing and potted plants.

A view of the ocean through a balcony railing with a clear sky.

A buffet setup with various food items including meats, pastries, and bread.

An arched entrance with a wooden floor leading into a corridor.

11. Domus Mariae Albergo

Ortigia

Marino

$97 nightly

$111 total

Nov 3 - Nov 4

Total with taxes and fees

A terrace with outdoor furniture, including sofas and chairs, arranged around a central table.

A hotel room with a bed, a desk with a lamp, a television, and a window with curtains.

An arched doorway leading to a balcony with potted plants and a wooden door.

A spacious living area with a round table, wicker chairs, a striped rug, and a sofa.

12. Lanterne Magiche Ortigia

Ortigia

Pablo

$101 nightly

$115 total

Nov 2 - Nov 3

Total with taxes and fees

An outdoor dining area with white tables and chairs, a staircase leading to an upper level, and a potted plant on the staircase.

A hotel room with a large bed, a bedside table, a chair, a wardrobe, and a mirror.

A hallway with a door, wall-mounted sconces, a small table with a lamp, and a staircase leading to another room.

A narrow street with buildings on either side, featuring a row of tables and chairs on the right side, suggesting a café or restaurant setting.

13. Hotel Gargallo

Ortigia

John

$101 nightly

$115 total

Nov 1 - Nov 2

Total with taxes and fees

A nighttime pool area with lounge chairs and umbrellas, surrounded by palm trees and a building with balconies.

A modern multi-story hotel with a central atrium, glass railings, and a well-maintained lawn.

An outdoor covered patio area with tables and chairs, a stone wall, and a palm tree.

A buffet with various fruits and pastries.

14. Eureka Palace Hotel Spa

Syracuse

IKECHUKWU

$77 nightly

$88 total

Nov 2 - Nov 3

Total with taxes and fees

A hallway with a series of framed artworks on the walls, a white floor, and recessed lighting.

A modern hotel room with a large bed, a desk, and a TV mounted on the wall.

A modern room with a flat-screen TV mounted on the wall, a small white table with two chairs, and a window with curtains.

A modern room with a white table and two chairs, a wardrobe, and two framed pictures of a night scene with a moon and a boat.

15. PhotoRooms B&B

Syracuse

Shpetim

$94 nightly

$97 total

Nov 5 - Nov 6

Total with taxes and fees

A courtyard with a large tree, stone walls, and a building with a tiled roof.

A swimming pool with clear water, surrounded by a wooden deck and several lounge chairs.

A bedroom with a bed, a chair, a small table, and a suitcase.

An interior courtyard with stone flooring, wicker furniture, and a decorative metal lantern.

16. Casa di Melo - Organic Country Hotel

Syracuse

Mary

$147 nightly

$168 total

Nov 4 - Nov 5

Total with taxes and fees

A modern hotel room with a flat-screen TV mounted on a dark wall, a white desk with a remote control, a bed with a black and white patterned bedspread, and a window with curtains.

A building facade with a classical architectural style, featuring a large arched window with blue curtains, a decorative balcony railing, and intricate stone carvings.

A modern, minimalist room with a sofa, a small table, and a desk with chairs.

A double wooden door with a sign above it reading "nostos ind & breakfast."

17. Nostos rooms & Apartments

Santa Lucia

Michael

$64 nightly

$73 total

Nov 3 - Nov 4

Total with taxes and fees

A narrow street with a building featuring a pink awning and a sign for 'Aretusa Vacanze'.

A narrow street with a building on the right featuring a large white planter with red flowers.

A staircase with a glass railing, a chair, and a small table with a lamp.

A narrow alleyway with buildings on either side, a street lamp, and string lights.

18. Aretusa Vacanze B&B

Ortigia

LILIYA

$103 nightly

$118 total

Nov 2 - Nov 3

Total with taxes and fees

A clear blue pool with lounge chairs and umbrellas, surrounded by palm trees and a covered seating area.

A two-story building with a beige facade, a gated entrance, and a sign that reads "KAONDIA".

A resort patio with palm trees, outdoor seating, and a pool area.

A modern hotel room with a bed, a desk, a chair, a television, and a view of the outdoors.

19. Life Hotels Kalaonda Resort

Syracuse

Hyun Jin

$98 nightly

$112 total

Oct 13 - Oct 14

Total with taxes and fees

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Stay near popular Isola attractions

Spiaggia Punta del Pero

Why not spend a lazy afternoon at Spiaggia Punta del Pero during your trip to Isola?

See properties

Top Isola Hotel Reviews

Maniace Boutique Hotel Ortigia UNA Esperienze

10/10 Excellent

"We arrived feeling stressed after the drive to the hotel! The lovely young lady on the front desk welcomed us with a warm Smile and arranged for the bartender to bring us a drink outside so we could soak up the afternoon sun and relax. We were served a delicious aperol. The decor throughout the hotel is very tasteful even the corridors to the room. Clean white walls but a hint of original brickwork showing. Comfy beds, crisp white linen. Lovely toiletries in the bathroom. Everywhere was spotless. Great breakfast and amazing service. Lovely location just opposite the pretty pebbly beach and around the corner from the lovely streets full of restaurants, shops and wonderful architecture. Would definitely return."

Hotel Porta Reale

10/10 Excellent

"Very convenient location. Right at the start of attractions. Excellent breakfast. Parking is a couple blocks away."

Lanterne Magiche Ortigia

10/10 Excellent

"I was so impressed with how spacious, clean and comfortable the rooms were, not to mention the amazing location. Staff were warm, welcoming and so helpful. I kept adding more days to my stay because I truly loved it here and felt so relaxed and at home. I will definitely be back in the future!"

Grand Hotel Villa Politi

8/10 Good

"We overall really enjoyed our 3 night stay here, and appreciated the quiet and historic charm of this hotel. It is an incredibly unique peace of property, with an attached historic Latomie that was both beautiful and intriguing—we really wished the hotel had access to explore the areas below. We also really appreciated the continental breakfast, and were surprised by other’s complaints in reviews we had read before staying here. It was the most elaborate continental breakfast we have ever experienced, with options ranging from fresh fruit, to delicious pastries, and even eggs and bacon for those with used to a more American meal. We loved the pool as well, however we were disappointed that it was only open until 7pm every day, we would have enjoyed an evening swim. The bar was also closed, though they provided service through the bar inside. We also really enjoyed the 2 for $22 aperitivo offered from the bar. The room we stayed in was small and a bit dated, but met our expectations for an older hotel. We also had issues with the AC not turning off and making our room very cold. We were able to find parking every night, however I would not describe it as a big parking lot, and it was overflowing every night with people crammed wherever they could find room."

Domus Mariae Albergo

10/10 Excellent

"Property is well located and staff was really helpful. If going in a rental, make sure you call ahead of time to register the car with the city and have a parking spot in one of the nearby garages. Parking is definitely scarce in Ortigia. The images from the hotel show a gym, that is a bit misleading."

Algila' Ortigia Charme Hotel

10/10 Excellent

"Beautiful hotel with wonderful hospitality We absolutely loved our stay at Hotel Algilà Ortigia Charme. From the moment we arrived, the staff were warm, friendly and genuinely welcoming. The hotel is full of Sicilian character and charm, and its location in Ortigia was perfect for exploring on foot. Our room was comfortable and beautifully suited to the character of the hotel, and the staff were always happy to help with recommendations and anything we needed. After travelling throughout Sicily for two weeks, what stood out most was the genuine hospitality. We felt like valued guests, not just another reservation. Algilà was exactly what we hoped for from a Sicilian hotel — charming, personal and welcoming. We would happily stay here again and highly recommend it to anyone visiting Ortigia!"

Grand Hotel Ortigia Siracusa

8/10 Good

"The hotel is conveniently located and balcony restaurant and bar had a great view."

Grande Albergo Alfeo

10/10 Excellent

"We enjoyed our stay"

Mangia's Brucoli, Sicily, Autograph Collection

10/10 Excellent

"Relaxing, beautiful surroundings, lots of space, never felt crowded, good choice of food venues and styles at restaurants, drinks always available."

More cheap stays in Isola

Nonna Nina

Via Beppe Montana 24 Avola SR

$62 nightly

$73 total

Oct 22 - Oct 23

Total with taxes and fees

Frequently asked questions

What's the best place for a stay in Isola?

Located 2.1 mi (3.5 km) from the heart of Isola, Algila' Ortigia Charme Hotel is a top choice for your stay based on our traveler data. Two other choices for your visit to the area are Mangia's Brucoli, Sicily, Autograph Collection and UNA Hotels One Siracusa Wellness & SPA. See all available top hotels, or vacation rentals in Isola.

What are some of the best vacation rentals that Isola has to offer?

Guest House Ortigia Calarossa: This vacation home rental outside Isola has air-conditioning and WiFi to help you feel perfectly comfortable in your new surroundings. Our travelers also rate With private tennis court, pool, 300m to the beach, WiFi, air con, max 7 guests as a favorite home for rent in Isola. See all vacation rentals in Isola.

If I need to cancel my hotel reservation in Isola, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Isola.

Where can I learn more about changing or cancelling my trip to Isola?

For additional details about rescheduling or cancelling your trip to Isola, go to https://www.expedia.com/service/.

What are some hotels with pools in Isola?

Mangia's Brucoli, Sicily, Autograph Collection: Provides 3 outdoor pools, a children's pool, and 5 restaurants. With private tennis court, pool, 300m to the beach, WiFi, air con, max 7 guests and Grand Hotel Villa Politi are a couple of other choices with an onsite pool. View all hotels with pools in Isola.

How is it to stay in Isola?

Those traveling to Isola are sure to enjoy the sights to see and things to do. In Isola, there are 17 hotels and other accommodations to choose from. Find out more about Isola.

What should I see while I'm in Isola?

A couple of favorite places to visit are Ionian Sea and Spiaggia Punta del Pero. You'll also find Tropical Aquarium of Syracuse and Cathedral of Syracuse in the area. Check out what more to see and do in Expedia's Isola guide.

What's the weather like in Isola?

The hottest months are usually August and July with an average temp of 78°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for Isola is 26 inches.

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Find hotels in Isola from $65

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Isola

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Isola hotels

1. Galatea e Giardino delle Esperidi apartments with pool by Wonderful Italy

2. Grand Hotel Villa Politi

3. Grande Albergo Alfeo

4. Albatros Hotel

5. UNA Hotels One Siracusa Wellness & SPA

6. CinqueSuites Ortigia

7. Algila' Ortigia Charme Hotel

8. Mercure Siracusa Prometeo

9. Hotel Como

10. Hotel Parco delle Fontane

11. Domus Mariae Albergo

12. Lanterne Magiche Ortigia

13. Hotel Gargallo

14. Eureka Palace Hotel Spa

15. PhotoRooms B&B

16. Casa di Melo - Organic Country Hotel

17. Nostos rooms & Apartments

18. Aretusa Vacanze B&B

19. Life Hotels Kalaonda Resort

Stay near popular Isola attractions

Spiaggia Punta del Pero

Top Isola Hotel Reviews

Maniace Boutique Hotel Ortigia UNA Esperienze

Hotel Porta Reale

Lanterne Magiche Ortigia

Grand Hotel Villa Politi

Domus Mariae Albergo

Algila' Ortigia Charme Hotel

Grand Hotel Ortigia Siracusa

Grande Albergo Alfeo

Mangia's Brucoli, Sicily, Autograph Collection

More cheap stays in Isola

Nonna Nina

Frequently asked questions

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