Top 10 Hotels in Murphy, MO (from $78) 2026 - Competitive Prices

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Our top choices for Murphy hotels

A modern hotel lobby with a high ceiling, a central seating area with sofas and a coffee table, and a flat-screen TV mounted on the wall.

An indoor swimming pool with a hot tub, lounge chairs, and a tiled floor.

A hotel room with a bed, a desk with a computer, a television, a sofa, and a window with a view.

A modern hotel breakfast area with a central island, buffet setup, and a large window providing a view.

1. Drury Inn & Suites Southwest St. Louis

Valley Park

Jeff

$115 nightly

$135 total

Oct 22 - Oct 23

Total with taxes and fees

A swimming pool with a metal ladder, surrounded by chairs and large windows offering a view of the sunset.

A modern dining area with multiple tables and chairs, large windows offering a view of the outdoors, and a mix of natural and artificial lighting.

A modern hotel lobby with a cityscape view, a reception desk, and ambient lighting.

A modern hotel lobby with a seating area, a desk, and large windows offering a view of the outside.

2. La Quinta Inn & Suites by Wyndham St Louis Route 66

St. Louis

Edward

$104 nightly

$117 total

Oct 18 - Oct 19

Total with taxes and fees

A hotel with a prominent tower, a fountain in the courtyard, and a well-maintained garden.

A modern bathroom with a large mirror, white vanity, and a bathtub.

A hotel room with a large bed, a bedside lamp, a telephone, a mirror, and a bathroom with a sink and towel rack.

A formal dining table set for six with a vase of white flowers, candles, and a view of buildings through large windows.

3. The Wildwood Hotel

Wildwood

Lori

$92 nightly

$107 total

Oct 26 - Oct 27

Total with taxes and fees

A modern dining area with multiple tables and chairs, recessed ceiling lights, and a kitchen in the background.

A hotel room with two beds, a desk, and a window with a view of trees.

An outdoor patio area with a fire pit, black metal chairs, and a blue umbrella.

An indoor swimming pool with tiled flooring, a pool ladder, and lounge chairs.

4. Best Western Plus Fenton

Fenton

$93 nightly

$107 total

Oct 18 - Oct 19

Total with taxes and fees

A hotel lobby with a staircase, dining area, and reception desk.

An indoor swimming pool with a tiled floor, a pool ladder, and a few chairs and tables around the pool area.

A building entrance with a black door, two potted trees, and a welcome sign.

A coffee station with two coffee machines, a shelf with coffee cups, and a storage area with boxes and a thermos.

5. Holiday Inn Express & Suites St. Louis West - Fenton by IHG

Fenton

Donna

$91 nightly

$105 total

Nov 15 - Nov 16

Total with taxes and fees

A modern interior with hanging pendant lights, large windows, and a view of the outside.

A hotel room with a flat-screen TV, a wooden cabinet, a light-colored sofa, a matching ottoman, and a small table.

A modern hotel with a covered entrance, brick facade, and a parking area.

A hotel indoor pool area with a hot tub, seating, and a view of the outdoors.

6. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Fenton

Dashaun

$89 nightly

$103 total

Nov 1 - Nov 2

Total with taxes and fees

A modern living area with a sofa, armchairs, a coffee table, and a kitchen in the background.

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

A modern living room with a sectional sofa, a round coffee table, and large windows offering a view of the city.

A modern lobby with a reception desk, seating area, and a fireplace.

7. Best Western St. Louis Inn

St. Louis

Harold

$68 nightly

$78 total

Oct 25 - Oct 26

Total with taxes and fees

A bar area with a long counter displaying numerous bottles of alcohol and several empty wine glasses lined up.

A gym with various exercise equipment, large windows, and a skylight.

A modern lobby with a grey sofa, two armchairs, a round table, and a chandelier. There are two posters on the wall and a reception desk in the background.

8. Holiday Inn St Louis SW - Route 66 by IHG

St. Louis

Eric

$113 nightly

$132 total

Nov 15 - Nov 16

Total with taxes and fees

A hotel room with a large bed, a desk, a chair, a TV, and a view of the city.

A hotel reception area with a desk, computer, printer, chairs, and a vase with flowers.

A room with a blue sofa, two cushions, a small table, and a wall-mounted light fixture.

A gym with exercise equipment, dumbbells, and motivational wall art.

9. Comfort Suites St. Louis - Sunset Hills

St. Louis

John

$118 nightly

$137 total

Oct 22 - Oct 23

Total with taxes and fees

A hotel room with two beds, a desk, a chair, a dresser, and a TV.

Two white cups of coffee on a reflective black surface with a glass of milk in the background.

A modern building with a brick facade and a green roof.

A dining area with wooden tables and chairs, a kitchen area with a coffee machine, and a brick wall.

10. Wingate by Wyndham St. Louis/Fenton Route 66

Fenton

Cooper

$79 nightly

$91 total

Oct 25 - Oct 26

Total with taxes and fees

A modern interior with a high ceiling, large windows, and a brick wall. There are orange chairs and a green sofa with orange cushions.

A modern indoor space with a large window, a seating area with sofas and chairs, and a dining area with tables and chairs.

A hotel room with a bed, a desk, a television, a sofa, and a lamp.

A modern building with a prominent entrance, large windows, and a covered parking area.

11. Pear Tree Inn St. Louis Arnold

Arnold

Lynda

$90 nightly

$104 total

Oct 21 - Oct 22

Total with taxes and fees

A spacious lobby with a high ceiling, modern lighting fixtures, a seating area with sofas and chairs, and a bar area with stools.

A modern kitchen with a sink, dishwasher, and microwave. There is a large mirror above the sink and a countertop with various items. The room has a neutral color scheme and a view of a living area with a couch and a TV.

A snack display area with various packaged snacks and a refrigerated section.

12. Hampton Inn & Suites St. Louis/South I-55

St. Louis

Kevin

$110 nightly

$126 total

Oct 25 - Oct 26

Total with taxes and fees

A lobby with a reception desk, blue sofas, a coffee table, and a plant display.

A spacious dining area with multiple tables and chairs, large windows, and ceiling lights.

A hotel room with a desk, two beds, a television, a lamp, and a cityscape painting on the wall.

A hotel room with a TV, a sofa, a small table, a lamp, and a carpeted floor.

13. Drury Inn & Suites St. Louis Arnold

Arnold

Bailey

$126 nightly

$146 total

Oct 25 - Oct 26

Total with taxes and fees

A modern kitchen with a bar area, wooden cabinets, and pendant lighting.

A modern hotel entrance with a glass canopy, large windows, and a brick facade.

A hotel room with three computer workstations, each with a monitor, keyboard, and a lamp.

A swimming pool with a tiled deck, a sunlit room with a view, and a seating area with chairs.

14. Hyatt Place St. Louis/Chesterfield

Chesterfield

Debbie

$130 nightly

$150 total

Oct 20 - Oct 21

Total with taxes and fees

A modern kitchen area with a breakfast bar, a coffee machine, and a refrigerator displaying menu options.

A hotel room with two beds, a blue sofa, a small table, and a kitchenette.

A coffee station with two coffee machines and a display of coffee pods and cups.

A Holiday Inn Express & Suites building with a brick facade, a covered entrance, and a numbered address.

15. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Chesterfield

Terry

$107 nightly

$125 total

Nov 15 - Nov 16

Total with taxes and fees

A hotel reception area with a counter, coffee machines, a refrigerated display, and artwork on the wall.

A hotel room with a bed, desk, TV, and a view of the outdoors.

A snack bar with shelves of chips, candies, and bottled water.

An indoor swimming pool with clear water, a diving board, and a seating area with tables and chairs.

16. Fairfield Inn & Suites by Marriott St. Louis Chesterfield

Chesterfield

Charles

$107 nightly

$124 total

Oct 26 - Oct 27

Total with taxes and fees

A spacious lobby with a central round table, two sofas, and a chandelier.

An indoor swimming pool area with clear signage indicating a depth of 3 feet and a no diving warning.

A hotel room with two beds, a patterned wall, and a view of the city through sheer curtains.

A buffet setup with various food items and a decorative vase of flowers.

17. Drury Plaza Hotel St. Louis Chesterfield

Chesterfield

Chasity

$130 nightly

$151 total

Oct 21 - Oct 22

Total with taxes and fees

Two people in a swimming pool with colorful inflatable rings.

A spacious lobby with a stone fireplace, a chandelier, and a staircase.

A buffet counter with a variety of food items, including pastries and beverages, and a person serving.

A hotel room with a large bed, a desk, a TV, and a view of a pool through the glass door.

18. Holiday Inn St. Louis West Six Flags by IHG

Eureka

Rob

$130 nightly

$151 total

Nov 16 - Nov 17

Total with taxes and fees

A modern kitchen with stainless steel appliances, a central island with stools, and a wine cooler.

A spacious living area with a fireplace, a television mounted above it, and a comfortable seating arrangement.

A spacious lobby with a seating area, a reception desk, and a kitchen area.

A Hilton Garden Inn with a brick facade, a covered entrance, and landscaped gardens.

19. Hilton Garden Inn Chesterfield

Chesterfield

Samantha

$105 nightly

$123 total

Nov 1 - Nov 2

Total with taxes and fees

An outdoor patio area with wicker furniture and a central fire feature.

A hotel room with a bed, a sofa, a desk, and a chair.

A modern hotel lobby with a reception desk, seating area, and a television screen displaying a map.

A Courtyard Marriott hotel with a parking lot and a green shuttle service.

20. Courtyard by Marriott St. Louis Chesterfield

Chesterfield

Kelly

$116 nightly

$135 total

Oct 29 - Oct 30

Total with taxes and fees

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Stay near popular attractions around Murphy

Murphy invites families and adventure seekers alike to explore its vibrant urban parks, scenic state parks, and thrilling amusement parks. Dive into a world of outdoor fun and cultural experiences that promise unforgettable memories for everyone!

A colorful LEGO display with various shapes and figures.

Magic House - St. Louis Children's Museum

9.2/10 (184 reviews)

An essential stop for families, the Magic House - St. Louis Children's Museum offers interactive exhibits and engaging activities that spark curiosity and creativity in children. Located about 8 miles from Murphy, it provides a fun-filled experience, making it an ideal destination for your family vacation.

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A river winding through a dense forest with hills in the background.

Castlewood State Park

A fascinating mix of adventure and natural beauty awaits outdoor enthusiasts at Castlewood State Park. With its stunning scenery and vibrant trails, this park offers a unique experience for those looking to explore the great outdoors. Located about 3 miles from Murphy, it’s a convenient spot for nature lovers to unwind and enjoy the landscape.

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A museum exhibit with vintage vehicles including a 1934 Ford Phalet car and a fire truck.

Museum of Transportation

5.0/10 (2 reviews)

Perfectly suited for families and culture seekers, the Museum of Transportation in Des Peres offers a captivating journey through the history of transport. Located about 6 miles from Murphy, this engaging museum showcases an impressive collection of vehicles and exhibits, making it a convenient stop for those exploring the area.

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A sculpture of large red metal structures in an open field.

Laumeier Sculpture Park

10.0/10 (1 review)

A must-see for families, Laumeier Sculpture Park offers a unique outdoor experience filled with stunning art installations nestled in nature. Located about 7 miles from Murphy, it's an easy visit that allows you to enjoy both creativity and fresh air, making it a perfect addition to your trip.

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Six Flags St. Louis

8.6/10 (618 reviews)

Set the stage for your family adventure at Six Flags St. Louis, an exciting amusement park located about 8 miles from Murphy. Enjoy thrilling rides, family-friendly attractions, and vibrant outdoor vibes that promise fun for all ages. Staying nearby makes it easy to dive into the excitement whenever you wish.

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Route 66 State Park

8.2/10 (25 reviews)

Often cited as a favorite for outdoor enthusiasts, Route 66 State Park offers adventure and scenic beauty. Just about 4 miles from Murphy, this park invites visitors to explore its unique landscapes and enjoy a day of relaxation. Staying nearby makes it easy to embrace the park’s outdoor vibes.

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Show Me

8.0/10 (2 reviews)

Ideal for families and couples seeking outdoor fun, Show Me in Eureka, Missouri, offers an exciting skiRun experience. With its welcoming atmosphere, visitors can enjoy winter activities suited for all skill levels. Located about 7 miles from Murphy, staying nearby makes it easy to access this thrilling destination.

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Lone Elk Park

9.0/10 (11 reviews)

No trip is complete without a visit to Lone Elk Park, a family-friendly reserve just 2 miles from Murphy, Missouri. Here, visitors can enjoy the beauty of nature and observe wildlife in a serene setting. Staying nearby offers easy access to this tranquil escape.

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Top Murphy Hotel Reviews

Clayton Plaza Hotel & Extended Stay

10/10 Excellent

"Have always loved this hotel and I have been staying here for 15 years. Clean, comfortable rooms, free parking and the best breakfast buffet you could ask for. The omelette bar is my favorite! Staff is always very kind and helpful."

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent

"The all day free fountain soda machine was fantastic! The view was great and overall experience was wonderful. I will stay here again!"

The Westin St. Louis

10/10 Excellent

"The bar experience left a little to be desired, but I was only there a couple times."

Pear Tree Inn St. Louis Airport

10/10 Excellent

"Nice and clean. Breakfast delicious 😋"

Live by Loews - St.Louis

10/10 Excellent

"Staff were very helpful and friendly.."

Ameristar Casino Resort and Spa

10/10 Excellent

"Very clean and professional"

Forest Park Hotel by MDR

8/10 Good

"We we ok ok ok"

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent

"Very cute hotel. Definitely would stay again. We were busy this trip so didn’t have time to check out the rooftop bar. Would have liked to have done that."

More cheap stays in Murphy

Best Western St. Louis Inn

6224 Heimos Industrial Park Dr St. Louis MO

$68 nightly

$78 total

Oct 25 - Oct 26

Total with taxes and fees

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO

$88 nightly

$104 total

Oct 21 - Oct 22

Total with taxes and fees

9.2/10 Wonderful! (3,296 reviews)

Tru By Hilton St. Louis Downtown

1221 Locus Street St. Louis MO

$93 nightly

$108 total

Nov 1 - Nov 2

Total with taxes and fees

The West End

4215 Lindell Blvd St. Louis MO

$112 nightly

$128 total

Oct 26 - Oct 27

Total with taxes and fees

8.6/10 Excellent! (685 reviews)

Hampton Inn St. Charles St. Peters

3720 W Clay St St. Charles MO

$119 nightly

$136 total

Oct 25 - Oct 26

Total with taxes and fees

8.2/10 Very Good! (1,003 reviews)

AC Hotel St. Louis Clayton

227 South Central Ave St. Louis MO

$135 nightly

$158 total

Oct 25 - Oct 26

Total with taxes and fees

Hotels in Murphy with star-rating

Frequently asked questions

What is the best area to stay in Murphy?

The best area to stay in Murphy, Missouri, is near the intersection of Manchester Road and Highway 141, offering convenient access to amenities and attractions.This area serves as a central hub for visitors, characterized by its selection of modern hotels and proximity to major roadways. Travelers will find easy access to dining, shopping, and entertainment options along Manchester Road, which runs east-west through the district. This layout makes it a practical base for exploring Murphy and the wider St. Louis metropolitan area.For families, this location is particularly advantageous due to its close proximity to Hidden Valley Ski Resort, located just a short drive away. Additionally, the nearby Myseum, with its interactive exhibits, provides an engaging experience for children, making it easy to plan family-friendly outings without extensive travel.Couples looking for a convenient and well-appointed stay will appreciate the range of hotels offering amenities like high-end fitness equipment and comfortable dining options.

When is the best time to go to Murphy?

The best time to visit Murphy, Missouri, is during the spring (April to May) and fall (September to October) months, when the weather is most pleasant for outdoor activities.During these periods, you'll experience mild temperatures and comfortable humidity levels, making it ideal for exploring local parks, hiking trails, and enjoying outdoor dining. The spring brings blooming flowers and lush greenery, while the fall offers colorful foliage, creating picturesque scenery for visitors.Families often find these seasons particularly appealing for visits to parks like Queeny Park, which offers extensive trails, playgrounds, and picnic areas without the intense heat or cold of other seasons.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Murphy.

How much is the nightly rate at a Murphy hotel?

Prices for hotels in Murphy often vary, but you can find a great deal from $78 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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Find hotels in Murphy, MO from $78

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Murphy

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Murphy hotels

1. Drury Inn & Suites Southwest St. Louis

2. La Quinta Inn & Suites by Wyndham St Louis Route 66

3. The Wildwood Hotel

4. Best Western Plus Fenton

5. Holiday Inn Express & Suites St. Louis West - Fenton by IHG

6. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

7. Best Western St. Louis Inn

8. Holiday Inn St Louis SW - Route 66 by IHG

9. Comfort Suites St. Louis - Sunset Hills

10. Wingate by Wyndham St. Louis/Fenton Route 66

11. Pear Tree Inn St. Louis Arnold

12. Hampton Inn & Suites St. Louis/South I-55

13. Drury Inn & Suites St. Louis Arnold

14. Hyatt Place St. Louis/Chesterfield

15. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

16. Fairfield Inn & Suites by Marriott St. Louis Chesterfield

17. Drury Plaza Hotel St. Louis Chesterfield

18. Holiday Inn St. Louis West Six Flags by IHG

19. Hilton Garden Inn Chesterfield

20. Courtyard by Marriott St. Louis Chesterfield

Stay near popular attractions around Murphy

Magic House - St. Louis Children's Museum

Castlewood State Park

Museum of Transportation

Laumeier Sculpture Park

Six Flags St. Louis

Route 66 State Park

Show Me

Lone Elk Park

Top Murphy Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Pear Tree Inn St. Louis Near Union Station

The Westin St. Louis

Pear Tree Inn St. Louis Airport

Live by Loews - St.Louis

Ameristar Casino Resort and Spa

Forest Park Hotel by MDR

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

More cheap stays in Murphy

Best Western St. Louis Inn

Pear Tree Inn St. Louis Airport

Tru By Hilton St. Louis Downtown

The West End

Hampton Inn St. Charles St. Peters

AC Hotel St. Louis Clayton

Hotels in Murphy with star-rating

Frequently asked questions

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