Title: Visit Santa Clara: 2026 Travel Guide for Santa Clara, Panamá Oeste Province | Expedia.com

[Hotels in Santa Clara](https://expedia.com/Santa-Clara-Hotels.d553248623287315690.Travel-Guide-Hotels)[Vacation Rentals in Santa Clara](https://expedia.com/Santa-Clara-Vacation-Rentals.d553248623287315690.Travel-Guide-VacationRentals)[Flights to Santa Clara](https://expedia.com/Cheap-Flights-To-Santa-Clara.d553248623287315690.Travel-Guide-Flights)[Things to do in Santa Clara](https://expedia.com/Things-To-Do-In-Santa-Clara.d553248623287315690.Travel-Guide-Activities)[Car Rentals in Santa Clara](https://expedia.com/Car-Rentals-In-Santa-Clara.d553248623287315690.Car-Rental-Guide)[Santa Clara Vacation Packages](https://expedia.com/Santa-Clara.d553248623287315690.Destination-Travel-Guides)

# Santa Clara

## Travel Guide

![Adobe](https://images.trvl-media.com/place/553248623287315690/4fe3b50e-a6f6-406a-8784-202fa5ed50eb.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

## Visit Santa Clara

Things to do

- Santa Clara Hotel Deals
- Vacation Rentals in Santa Clara

![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama

$157 nightly

$172 total

Mar 30 - Mar 31

Total with taxes and fees

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...

9/10 Wonderful! (5,106 reviews)

Clean and comfortable room. Staff were very nice and breakfast was delicious.

Reviewed on Mar 17, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F30%2F2026&endDate=3%2F31%2F2026&selected=3900395&PinnedHotelID=3900395&HadPinnedHotel=true&regionId=553248623287315690)

![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Sheraton Grand Panama

Via Israel And 77th Street Panama City Panama

$134 nightly

$148 total

Apr 3 - Apr 4

Total with taxes and fees

Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...

8.6/10 Excellent! (1,014 reviews)

El personal de servicio excelente muy amables y te ayudaban a encontrar lugares para visitar

Reviewed on Mar 16, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F3%2F2026&endDate=4%2F4%2F2026&selected=1161&PinnedHotelID=1161&HadPinnedHotel=true&regionId=553248623287315690)

![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Via Espana 111 Panama City Panama

$103 nightly

$113 total

Mar 24 - Mar 25

Total with taxes and fees

Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...

7.8/10 Good! (1,005 reviews)

My stay here was really great. Close to everything, a safe area, wonderful happy friendly staff, awesome breakfast & the premises clean. I'll stay here again certainly.

Reviewed on Mar 15, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F24%2F2026&endDate=3%2F25%2F2026&selected=7164&PinnedHotelID=7164&HadPinnedHotel=true&regionId=553248623287315690)

[See all 1,600 properties in Santa Clara](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F18%2F2026&endDate=3%2F19%2F2026&regionId=553248623287315690)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

![Arcadia Condo Suites](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81757b88_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Arcadia Condo Suites

Calle rio mar Panama City Panamá Province

Stay at this aparthotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Popular attractions Multiplaza Pacific Mall and Avenida Balboa ...

9.4/10 Exceptional! (238 reviews)

Nice apartment in a nice location

Reviewed on Mar 15, 2026

[](https://expedia.com/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information)

![Marriott Executive Apartments Panama City, Finisterre](https://images.trvl-media.com/lodging/5000000/4960000/4959000/4958983/b4d43ebd_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Marriott Executive Apartments Panama City, Finisterre

Calle Colombia Y Ave.,3ra A Sur, Bella V Panama City Panama

Book a stay at this business-friendly aparthotel in Panama City. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the helpful staff in our ...

8.8/10 Excellent! (701 reviews)

The rooms were spacious. The housekeeping was good and attentive. Everything was fine.

Reviewed on Mar 9, 2026

[](https://expedia.com/Panama-City-Hotels-Marriott-Executive-Apartments-Panama-City.h4958983.Hotel-Information)

![Casco View Apartments](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/w846h1318x0y4-5df5c378_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Casco View Apartments

C. 16 Oeste Panama City Provincia de Panamá

Book a stay at this business-friendly condo in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Cinta Costera ...

9/10 Wonderful! (78 reviews)

Honest review of apartments clean well organized minimalist, but with ok essentials in the kitchens, paper towels., few cleaning supplies look under sink., everything neat in and order. Large sliding glass window, but the view is of interesting neighborhood) ocean (window in bedroom is to hallway) ...

Reviewed on Mar 6, 2026

[](https://expedia.com/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information)

[See all properties in Santa Clara](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&regionId=553248623287315690&sort=VACATION_RENTAL)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Check Santa Clara hotel availability

[Tonight

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248623287315690&startDate=2026-03-17&endDate=2026-03-18)[Mar 17 - Mar 18](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248623287315690&startDate=2026-03-17&endDate=2026-03-18)

[Tomorrow night

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248623287315690&startDate=2026-03-18&endDate=2026-03-19)[Mar 18 - Mar 19](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248623287315690&startDate=2026-03-18&endDate=2026-03-19)

[This weekend

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248623287315690&startDate=3%2F20%2F2026&endDate=3%2F22%2F2026)[Mar 20 - Mar 22](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248623287315690&startDate=3%2F20%2F2026&endDate=3%2F22%2F2026)

[Next weekend

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248623287315690&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026)[Mar 27 - Mar 29](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248623287315690&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026)

### Popular places to visit

#### Culebra Cut

4/5(11 reviews)

You can find out about the history of Santa Clara with a visit to Culebra Cut. Check out the casinos and top-notch restaurants in this walkable area. 

[](https://expedia.com/Culebra-Cut-Santa-Clara.d6078511.Vacation-Attraction)

### Things to do

![Monkey and Sloth Jungle Habitat Panama Tour ](https://mediaim.expedia.com/localexpert/47313144/f3dd1c31-b1f2-41ca-8793-3abcbc166e9d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Monkey and Sloth Jungle Habitat Panama Tour

$60

per adult

**100%** of travellers recommend

[](https://expedia.com/things-to-do/monkey-and-sloth-jungle-habitat-panama-tour.a47313144.activity-details)

![MiraLift](https://mediaim.expedia.com/localexpert/1116180/4f40785f-2369-4d7c-83f7-b0a5cc7ac401.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Transfer to Panama Canal (Miraflores Locks)

$14

per adult

**100%** of travellers recommend

[](https://expedia.com/things-to-do/transfer-to-panama-canal-miraflores-locks.a1116180.activity-details)

![Miraflores Visitor Center](https://mediaim.expedia.com/localexpert/46047029/083c00ba-6601-4577-82c0-65103ac0b91f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Panamá Canal and Old Town

$80

per adult

[](https://expedia.com/things-to-do/panama-canal-and-old-town.a46047029.activity-details)

![Panama Canal Tour: Miraflores Visitor Center & IMAX 3D Movie](https://mediaim.expedia.com/localexpert/46138380/1a5ce43d-e3b6-42ed-9045-7c63a1cda62d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Panama Canal Tour: Miraflores Visitor Center & IMAX - Afternoon

$35

per adult

[](https://expedia.com/things-to-do/panama-canal-tour-miraflores-visitor-center-imax-afternoon.a46138380.activity-details)

![5hour tour of Panama City and Panama Canal - Shared or Private](https://mediaim.expedia.com/localexpert/46748153/8351fdce-6999-4a6c-9037-aa2bc084f123.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### 5hour tour of Panama City and Panama Canal - Shared or Private

$65

per adult

**100%** of travellers recommend

[](https://expedia.com/things-to-do/5hour-tour-of-panama-city-and-panama-canal-shared-or-private.a46748153.activity-details)

![Panama City Tour](https://mediaim.expedia.com/localexpert/1013018/eaf5b8bd-4dd7-4f4b-9631-a757f2176e1f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Panama City Tour (Panama Canal, Old Town And Causeway)

$105

per adult

[](https://expedia.com/things-to-do/panama-city-tour-panama-canal.a1013018.activity-details)

[See all activities in Santa Clara](https://expedia.com/Things-To-Do-In-Santa-Clara.d553248623287315690.Travel-Guide-Activities)

## Cities near Santa Clara

![default](https://images.trvl-media.com/place/2897/9a0fe9cb-10b8-4a85-b416-4677f1455ea0.jpg?impolicy=fcrop&w=512&h=288&q=medium)

### Panama City

![Protected nature surrounding Gatun Lake, a freshwater artificial lake to the south of Colón, Panama. It forms a major part of the Panama Canal](https://images.trvl-media.com/place/601867/0f4b2986-19e2-41b5-93da-ec0bc70c4cc2.jpg?impolicy=fcrop&w=512&h=288&q=medium)

### Colon

![Adobe](https://images.trvl-media.com/place/6025059/97ff43ac-1acd-430b-9f47-7dcfb6cb44b8.jpg?impolicy=fcrop&w=512&h=288&q=medium)

### Gamboa

![Adobe](https://images.trvl-media.com/place/553248635921431980/08f3117c-1641-4cbd-a4d6-07c2d5757057.jpg?impolicy=fcrop&w=512&h=288&q=medium)

### Ancon

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