$543 Cheap Flights from Lisbon (LIS) to St. Louis (STL)

View $543 flight on Mon, May 18, 2026Opens in a new window

Popular airlines from Humberto Delgado Airport (LIS) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Lisbon to St. Louis (LIS-STL)

Prices were available within the past 7 days and start at $543 for one-way flights and $735 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Iberia
Thu, Dec 4 - Mon, Dec 8
LIS
Lisbon
STL
St. Louis
$735 Roundtrip, found 1 day ago
$735
Roundtrip
found 1 day ago
Select Iberia flight, departing Thu, Dec 4 from Lisbon to St. Louis, returning Mon, Dec 8, priced at $735 found 1 day ago
British Airways
Thu, Dec 4 - Mon, Dec 8
LIS
Lisbon
STL
St. Louis
$735 Roundtrip, found 1 day ago
$735
Roundtrip
found 1 day ago
Select British Airways flight, departing Thu, Dec 4 from Lisbon to St. Louis, returning Mon, Dec 8, priced at $735 found 1 day ago
American Airlines
Sat, Feb 14 - Sun, Feb 22
LIS
Lisbon
STL
St. Louis
$735 Roundtrip, found 1 day ago
$735
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Feb 14 from Lisbon to St. Louis, returning Sun, Feb 22, priced at $735 found 1 day ago
British Airways
Thu, Dec 4 - Mon, Dec 8
LIS
Lisbon
STL
St. Louis
$737 Roundtrip, found 1 day ago
$737
Roundtrip
found 1 day ago
Select British Airways flight, departing Thu, Dec 4 from Lisbon to St. Louis, returning Mon, Dec 8, priced at $737 found 1 day ago
American Airlines
Mon, Dec 1 - Mon, Dec 15
LIS
Lisbon
STL
St. Louis
$740 Roundtrip, found 4 days ago
$740
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, Dec 1 from Lisbon to St. Louis, returning Mon, Dec 15, priced at $740 found 4 days ago
British Airways
Sat, Nov 22 - Fri, Nov 28
LIS
Lisbon
STL
St. Louis
$745 Roundtrip, found 3 days ago
$745
Roundtrip
found 3 days ago
Select British Airways flight, departing Sat, Nov 22 from Lisbon to St. Louis, returning Fri, Nov 28, priced at $745 found 3 days ago
Iberia
Fri, Oct 10 - Wed, Oct 22
LIS
Lisbon
STL
St. Louis
$747 Roundtrip, found 1 day ago
$747
Roundtrip
found 1 day ago
Select Iberia flight, departing Fri, Oct 10 from Lisbon to St. Louis, returning Wed, Oct 22, priced at $747 found 1 day ago
British Airways
Thu, Dec 4 - Mon, Dec 8
LIS
Lisbon
STL
St. Louis
$749 Roundtrip, found 1 day ago
$749
Roundtrip
found 1 day ago
Select British Airways flight, departing Thu, Dec 4 from Lisbon to St. Louis, returning Mon, Dec 8, priced at $749 found 1 day ago
Lufthansa
Fri, Nov 28 - Fri, Dec 5
LIS
Lisbon
STL
St. Louis
$839 Roundtrip, found 3 days ago
$839
Roundtrip
found 3 days ago
Select Lufthansa flight, departing Fri, Nov 28 from Lisbon to St. Louis, returning Fri, Dec 5, priced at $839 found 3 days ago
United
Fri, Nov 28 - Fri, Dec 5
LIS
Lisbon
STL
St. Louis
$862 Roundtrip, found 3 days ago
$862
Roundtrip
found 3 days ago
Select United flight, departing Fri, Nov 28 from Lisbon to St. Louis, returning Fri, Dec 5, priced at $862 found 3 days ago

Frequently asked questions

How much does a flight from Humberto Delgado Airport (LIS) to Lambert-St. Louis Intl. Airport (STL) cost?
Grab a cheap one-way flight from $543 or cheap return flight from $735 from Humberto Delgado Airport (LIS) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Humberto Delgado Airport (LIS) to Lambert-St. Louis Intl. Airport (STL)?
The cheapest month to fly from LIS to STL is December, when there's less demand. Off-peak season is typically when you'll find cheap fares for travel between these airports.
What is the cheapest airline that flies from Humberto Delgado Airport (LIS) to Lambert-St. Louis Intl. Airport (STL)?
To find the cheapest airline flying from LIS to STL, use Expedia's filter tool. Tailor your search based on what's important to you, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Humberto Delgado Airport (LIS) to Lambert-St. Louis Intl. Airport (STL)?
Direct flights from Humberto Delgado Airport (LIS) to Lambert-St. Louis Intl. Airport (STL) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from LIS to STL?
Usually you'll find the widest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can vary based on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Humberto Delgado Airport (LIS) to Lambert-St. Louis Intl. Airport (STL)?
To land at Lambert-St. Louis Intl. Airport (STL) without delays, book a flight that takes off from Humberto Delgado Airport (LIS) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Humberto Delgado Airport (LIS) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Last-minute fares from LIS to STL are generally more expensive. To secure the best prices, start searching for flights as early as possible. That being said, if you're flexible with your travel plans, you may land a cheap ticket right before you leave.
Is it cheaper to book a LIS to STL flight and hotel package?
Booking a LIS to STL flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Choose from our impressive range of hotels and then add activities, flights and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Humberto Delgado Airport (LIS) to Lambert-St. Louis Intl. Airport (STL)?
Typically, you can modify or cancel your LIS to STL flight. However, additional charges may apply, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's fees and guidelines on flight changes, or if you need more details, go to our Customer Service portal.

Travel information

Travel information

Origin airport
Humberto Delgado
Destination airport
Lambert-St. Louis Intl.
Airlines serving
Aer Lingus, Air Canada, British Airways, Brussels Airlines, Finnair, Iberia, Lufthansa, Virgin Atlantic
Roundtrip price
$734
Distance
4215 mi

Book with confidence

Book with confidence

Lisbon to St. Louis Flights

The cheapest times to fly from Lisbon to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Lisbon to St. Louis are during the month of December. You can find some of the cheapest flights from Lisbon to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Lisbon to St. Louis

Sunday is one of the best days to book for cheap flights from Lisbon to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Lisbon to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Lisbon to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $543 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Lisbon to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Lisbon to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Lisbon to St. Louis Flights

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*Available to One Key members.