$126 Cheap Flights from Pittsburgh (PIT) to Knoxville (TYS)

View $126 flight on Wed, Dec 10, 2025Opens in a new window

Popular airlines from Pittsburgh Intl. Airport (PIT) to McGhee Tyson Airport (TYS)

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Cheap Flights from Pittsburgh to Knoxville (PIT-TYS)

Prices were available within the past 7 days and start at $126 for one-way flights and $251 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Dec 10 - Wed, Dec 17
PIT
Pittsburgh
TYS
Knoxville
$251 Roundtrip, just found
$251
Roundtrip
just found
Select American Airlines flight, departing Wed, Dec 10 from Pittsburgh to Knoxville, returning Wed, Dec 17, priced at $251 just found
Delta
Wed, Dec 10 - Wed, Dec 17
PIT
Pittsburgh
TYS
Knoxville
$251 Roundtrip, just found
$251
Roundtrip
just found
Select Delta flight, departing Wed, Dec 10 from Pittsburgh to Knoxville, returning Wed, Dec 17, priced at $251 just found
United
Wed, Dec 10 - Wed, Dec 17
PIT
Pittsburgh
TYS
Knoxville
$251 Roundtrip, just found
$251
Roundtrip
just found
Select United flight, departing Wed, Dec 10 from Pittsburgh to Knoxville, returning Wed, Dec 17, priced at $251 just found
United
Wed, Feb 18 - Tue, Feb 24
PIT
Pittsburgh
TYS
Knoxville
$253 Roundtrip, found 5 days ago
$253
Roundtrip
found 5 days ago
Select United flight, departing Wed, Feb 18 from Pittsburgh to Knoxville, returning Tue, Feb 24, priced at $253 found 5 days ago
American Airlines
Sat, Dec 13 - Tue, Dec 16
PIT
Pittsburgh
TYS
Knoxville
$255 Roundtrip, found 1 day ago
$255
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Dec 13 from Pittsburgh to Knoxville, returning Tue, Dec 16, priced at $255 found 1 day ago
United
Wed, Dec 10 - Wed, Dec 17
PIT
Pittsburgh
TYS
Knoxville
$256 Roundtrip, just found
$256
Roundtrip
just found
Select United flight, departing Wed, Dec 10 from Pittsburgh to Knoxville, returning Wed, Dec 17, priced at $256 just found
United
Wed, Feb 18 - Tue, Feb 24
PIT
Pittsburgh
TYS
Knoxville
$264 Roundtrip, found 5 days ago
$264
Roundtrip
found 5 days ago
Select United flight, departing Wed, Feb 18 from Pittsburgh to Knoxville, returning Tue, Feb 24, priced at $264 found 5 days ago
United
Wed, Feb 18 - Tue, Feb 24
PIT
Pittsburgh
TYS
Knoxville
$267 Roundtrip, found 5 days ago
$267
Roundtrip
found 5 days ago
Select United flight, departing Wed, Feb 18 from Pittsburgh to Knoxville, returning Tue, Feb 24, priced at $267 found 5 days ago
Southwest Airlines
Tue, Apr 7 - Sat, Apr 11
PIT
Pittsburgh
TYS
Knoxville
$312 Roundtrip, found 3 hours ago
$312
Roundtrip
found 3 hours ago
Select Southwest Airlines flight, departing Tue, Apr 7 from Pittsburgh to Knoxville, returning Sat, Apr 11, priced at $312 found 3 hours ago
Frontier Airlines
Mon, Dec 22 - Thu, Dec 25
PIT
Pittsburgh
TYS
Knoxville
$316 Roundtrip, found 6 days ago
$316
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Mon, Dec 22 from Pittsburgh to Knoxville, returning Thu, Dec 25, priced at $316 found 6 days ago

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Find the cheapest month to fly from Pittsburgh (PIT) to Knoxville (TYS)

April is typically the cheapest month to fly

From $198 - $418 per traveler.

Alternative airports near Knoxville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to McGhee Tyson TYS. Cheapest and Closest option available. Average driving time to city center is 22 minutes. Flights from $251
TYS
McGhee Tyson
CheapestClosest
Average driving time to city center22 min
Flights from $251
Flights from Pittsburgh (PIT) to Knoxville (TYS)
Origin airport
Pittsburgh Intl.
Destination airport
McGhee Tyson
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$250
Distance
382 mi

Pittsburgh to Knoxville Flights

The cheapest times to fly from Pittsburgh to Knoxville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Pittsburgh to Knoxville are during the month of December. You can find some of the cheapest flights from Pittsburgh to Knoxville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Pittsburgh to Knoxville

Sunday is one of the best days to book for cheap flights from Pittsburgh to Knoxville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Pittsburgh to Knoxville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Pittsburgh to Knoxville in 2025. You can also book with separate airlines for your outbound and return journeys, from $126 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Pittsburgh to Knoxville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Pittsburgh to Knoxville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Pittsburgh Intl. Airport (PIT) to McGhee Tyson Airport (TYS) cost?
Grab a cheap one-way flight from $126 or cheap return flight from $251 from Pittsburgh Intl. Airport (PIT) to McGhee Tyson Airport (TYS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Pittsburgh Intl. Airport (PIT) to McGhee Tyson Airport (TYS)?
December is the cheapest month to fly from PIT to TYS. Traveling during quieter months is often the key to landing a great deal.
What is the cheapest airline that flies from Pittsburgh Intl. Airport (PIT) to McGhee Tyson Airport (TYS)?
Use the filters on Expedia to compare different airlines and find the cheapest carrier that'll take you from PIT to TYS. Then, sort your results by "Price (lowest to highest)" to snag a great deal.
How many flights per day from Pittsburgh Intl. Airport (PIT) to McGhee Tyson Airport (TYS)?
You'll need to catch a flight with a layover if you're traveling from Pittsburgh Intl. Airport (PIT) to McGhee Tyson Airport (TYS). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to find the best option for your trip.
What day of the week has the most flights from PIT to TYS?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can vary depending on a range of factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What airline has the least delays from PIT to TYS?
Consider traveling with United Airlines if you'd like to fly straight from Pittsburgh Intl. Airport (PIT) to McGhee Tyson Airport (TYS) without any interruptions. This airline has the best track record for punctuality, with an on-time score of 100%. Want real-time updates? You can keep an eye on your flight status using the Expedia App.
What is the best time to fly from Pittsburgh Intl. Airport (PIT) to McGhee Tyson Airport (TYS)?
To avoid possible delays on the Pittsburgh Intl. Airport (PIT) to McGhee Tyson Airport (TYS) route, travel before 3 PM. Flights after this time have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Pittsburgh Intl. Airport (PIT) to McGhee Tyson Airport (TYS) last-minute?
Waiting until right before your break to book your flight from PIT to TYS often results in higher prices. While you may come across some last-minute deals, they aren't always guaranteed. Allow some flexibility in your schedule for the best chance of scoring a bargain.
Is it cheaper to book a PIT to TYS flight and hotel package?
Securing a PIT to TYS flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Choose from our extensive range of stays and then add activities, car rentals and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Pittsburgh Intl. Airport (PIT) to McGhee Tyson Airport (TYS)?
In most instances, you're able to reschedule or cancel your PIT to TYS flight. However, additional fees may apply, especially if you booked over 24 hours ago. Check your itinerary for the airline's fees and policies on flight changes, or if you need more details, head to our Customer Service portal.

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*Available to One Key members.