Featured airlines
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 30% on select hotels after you book a flight*
Cheap Flights from San Francisco to Santiago (SFO-SCL)
Prices were available within the past 7 days and start at $262 for one-way flights and $537 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Origin airport | San Francisco Intl. |
Destination airport | Arturo Merino Benitez |
Airlines serving | Aeromexico, Air Canada, American Airlines, Copa, Delta, LATAM Airlines Group, United, avianca |
Roundtrip price | $536 |
Distance | 5921 mi |
San Francisco to Santiago Flights
Whether you’re looking for a grand adventure or just want to get away for a last-minute break, flights from San Francisco to Santiago offer the perfect respite. Not only does exploring Santiago provide the chance to make some magical memories, dip into delectable dishes, and tour the local landmarks, but the cheap airfare means you won’t bust your budget. So no matter whether your ideal itinerary involves flying one way, non-stop, or round trip, you’re bound to find flights that match your schedule on Expedia, and at prices that won’t shock your wallet.
Bagging a cheap flight from San Francisco to Santiago may mean more dollars to spend on for one-of-a-kind souvenirs when you arrive, but it doesn’t mean you have to skimp on your travel experience, as Expedia offers a sizzling selection of cheap airlines that’ll put you in your happy place on their planes, whether that’s getting lost in a hair-raising airport thriller, dreaming on the passing landscape over a glass of bubbly, or jotting down your vacation bucket list at 38,000 feet. There’s also bound to be plenty of opportunities to snap a few photos of the high life that will make your friends green with envy. After all, enjoying the journey is part of the fun.
With so many affordable flights and so many wonderful adventures awaiting you, there’s no reason to put off booking a fantastic flight from to today. So don’t leave it to the last minute to make your dream trip a reality: pack your bags with your go-to travel accessories, put together your list of must-see attractions and can’t-miss activities, and get ready to broaden your horizons – with Expedia, the wonders of Santiago are only a plane trip away. Book your travel arrangements with us today!
If you would like to book flights to Santiago more flexibly many prefer to purchase one-way tickets with options to take different airlines. A one way ticket to Santiago is $262 now!
Frequently asked questions
- Trending Routes
- Trending Flights
- Top Flights Destinations
- More Popular Airlines
- Nearby Airports
- Flights From Other Airports
- Expedia's Latest Trends
Top Routes from San Francisco
- San Francisco to Chicago (SFO - ORD)
- San Francisco to Newark (SFO - EWR)
- San Francisco to San Diego (SFO - SAN)
- San Francisco to Mexico City (SFO - MEX)
- San Francisco to Los Angeles (SFO - LAX)
- San Francisco to Hong Kong (SFO - HKG)
- San Francisco to Honolulu (SFO - HNL)
- San Francisco to New York (SFO - LGA)
- San Francisco to Boston (SFO - BOS)
- San Francisco to Manila (SFO - MNL)
- San Francisco to Delhi (SFO - DEL)
- San Francisco to San José del Cabo (SFO - SJD)
Top Routes to Santiago
- Chicago to Santiago (ORD - SCL)
- Newark to Santiago (EWR - SCL)
- Los Angeles to Santiago (LAX - SCL)
- Washington to Santiago (DCA - SCL)
- Miami to Santiago (MIA - SCL)
- New York to Santiago (LGA - SCL)
- Boston to Santiago (BOS - SCL)
- São Paulo to Santiago (GRU - SCL)
- Buenos Aires to Santiago (AEP - SCL)
- Washington to Santiago (IAD - SCL)
- New York to Santiago (JFK - SCL)
- Houston to Santiago (IAH - SCL)
Top Routes from San Francisco
- Alaska Airlines San Francisco to Chicago
- Alaska Airlines San Francisco to Newark
- Alaska Airlines San Francisco to San Diego
- Aeromexico San Francisco to Mexico City
- Alaska Airlines San Francisco to Los Angeles
- Alaska Airlines San Francisco to Honolulu
- Alaska Airlines San Francisco to Boston
- EVA Airways San Francisco to Manila
- Qatar Airways San Francisco to Delhi
- Alaska Airlines San Francisco to San José del Cabo
Top Flight Destinations
- Flights to Santiago
- Flights to San Pedro de Atacama
- Flights to Vina del Mar
- Flights to Torres del Paine
- Flights to Valparaiso
- Flights to Valle Nevado
- Flights to Hanga Roa
- Flights to Antofagasta
- Flights to Puerto Varas
- Flights to Punta Arenas
- Flights to Farellones
- Flights to Pucón
- Flights to Puerto Montt
- Flights to Concepción
- Flights to La Serena
- Flights to Iquique
- Flights to Temuco
- Flights to Valdivia
- Flights to Calama
- Flights to Santa Cruz
San Jose
Oakland
Nearby Airports
- San Carlos Airport (SQL)
- Oakland Intl. Airport (OAK)
- Norman Y. Mineta San Jose Intl. Airport (SJC)
- Buchanan Field Airport (CCR)
- Watsonville Municipal Airport (WVI)
- Stockton Municipal Airport (SCK)
- Sonoma County Airport (STS)
- Monterey Peninsula Airport (MRY)
- Salinas Municipal Airport (SNS)
- Modesto City - County Airport (MOD)